-
1
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
The Huntington's Disease Collaborative Research Group
-
The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993; 72 (6): 971-983
-
(1993)
Cell
, vol.72
, Issue.6
, pp. 971-983
-
-
-
2
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
-
Nucifora Jr FC, Sasaki M, Peters MF, et al. Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science 2001; 291 (5512): 2423-2428
-
(2001)
Science
, vol.291
, Issue.5512
, pp. 2423-2428
-
-
Nucifora Jr, F.C.1
Sasaki, M.2
Peters, M.F.3
-
3
-
-
66749167799
-
Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity
-
Subramaniam S, Sixt KM, Barrow R, et al. Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity. Science 2009; 324 (5932): 1327-1330
-
(2009)
Science
, vol.324
, Issue.5932
, pp. 1327-1330
-
-
Subramaniam, S.1
Sixt, K.M.2
Barrow, R.3
-
4
-
-
33947604998
-
Complex movement behaviour and progression of Huntington's disease
-
Andrich J, Saft C, Ostholt N, et al. Complex movement behaviour and progression of Huntington's disease. Neurosci Lett 2007; 416 (3): 272-274
-
(2007)
Neurosci Lett
, vol.416
, Issue.3
, pp. 272-274
-
-
Andrich, J.1
Saft, C.2
Ostholt, N.3
-
5
-
-
33646686133
-
Functional decline due to chorea in Huntington's disease
-
Frank S, Marshall F, Plumb S, et al. Functional decline due to chorea in Huntington's disease. Neurology 2004; 62 Suppl. 5: A204
-
(2004)
Neurology
, vol.62
, Issue.SUPPL. 5
-
-
Frank, S.1
Marshall, F.2
Plumb, S.3
-
6
-
-
0037056392
-
Huntington's disease: A randomized, controlled trial using the NMDA-antagonist amantadine
-
Verhagen ML, Morris MJ, Farmer C, et al. Huntington's disease: a randomized, controlled trial using the NMDA-antagonist amantadine. Neurology 2002; 59 (5): 694-699
-
(2002)
Neurology
, vol.59
, Issue.5
, pp. 694-699
-
-
Verhagen, M.L.1
Morris, M.J.2
Farmer, C.3
-
7
-
-
0038701684
-
Huntingtin aggregation and toxicity in Huntington's disease
-
Bates G. Huntingtin aggregation and toxicity in Huntington's disease. Lancet 2003; 361 (9369): 1642-1644
-
(2003)
Lancet
, vol.361
, Issue.9369
, pp. 1642-1644
-
-
Bates, G.1
-
8
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
Arrasate M, Mitra S, Schweitzer ES, et al. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 2004; 431 (7010): 805-810
-
(2004)
Nature
, vol.431
, Issue.7010
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
-
9
-
-
0034081681
-
The pattern of neurodegeneration in Huntington's disease: A comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease
-
Glass M, Dragunow M, Faull RL. The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease. Neuroscience 2000; 97 (3): 505-519
-
(2000)
Neuroscience
, vol.97
, Issue.3
, pp. 505-519
-
-
Glass, M.1
Dragunow, M.2
Faull, R.L.3
-
10
-
-
0026717486
-
Preferential loss of striato-external pallidal projection neurons in pre-symptomatic Huntington's disease
-
Albin RL, Reiner A, Anderson KD, et al. Preferential loss of striato-external pallidal projection neurons in pre-symptomatic Huntington's disease. Ann Neurol 1992; 31 (4): 425-430
-
(1992)
Ann Neurol
, vol.31
, Issue.4
, pp. 425-430
-
-
Albin, R.L.1
Reiner, A.2
Anderson, K.D.3
-
11
-
-
0001589776
-
Differential loss of striatal projection neurons in Huntington disease
-
Reiner A, Albin RL, Anderson KD, et al. Differential loss of striatal projection neurons in Huntington disease. Proc Natl Acad Sci USA 1988; 85 (15): 5733-5737
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, Issue.15
, pp. 5733-5737
-
-
Reiner, A.1
Albin, R.L.2
Anderson, K.D.3
-
12
-
-
0032860432
-
The selective vulnerability of striatopallidal neurons
-
Mitchell IJ, Cooper AJ, Griffiths MR. The selective vulnerability of striatopallidal neurons. Prog Neurobiol 1999; 59 (6): 691-719
-
(1999)
Prog Neurobiol
, vol.59
, Issue.6
, pp. 691-719
-
-
Mitchell, I.J.1
Cooper, A.J.2
Griffiths, M.R.3
-
13
-
-
12644252940
-
Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Hunting-ton's disease
-
Antonini A, Leenders KL, Spiegel R, et al. Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Hunting-ton's disease. Brain 1996; 119 (Pt 6): 2085-2095
-
(1996)
Brain
, vol.119
, Issue.PART 6
, pp. 2085-2095
-
-
Antonini, A.1
Leenders, K.L.2
Spiegel, R.3
-
14
-
-
0030612119
-
Dopamine D1 and D2 receptor gene expression in the striatum in Huntington's disease
-
Augood SJ, Faull RL, Emson PC. Dopamine D1 and D2 receptor gene expression in the striatum in Huntington's disease. Ann Neurol 1997; 42 (2): 215-221
-
(1997)
Ann Neurol
, vol.42
, Issue.2
, pp. 215-221
-
-
Augood, S.J.1
Faull, R.L.2
Emson, P.C.3
-
15
-
-
35648963039
-
Thalamic metabolism and symptom onset in preclinical Huntington's disease
-
Feigin A, Tang C, Ma Y, et al. Thalamic metabolism and symptom onset in preclinical Huntington's disease. Brain 2007; 130 (Pt 11): 2858-2867
-
(2007)
Brain
, vol.130
, Issue.PART 11
, pp. 2858-2867
-
-
Feigin, A.1
Tang, C.2
Ma, Y.3
-
16
-
-
0032747164
-
Huntington's disease progression PET and clinical observations
-
Andrews TC, Weeks RA, Turjanski N, et al. Huntington's disease progression. PET and clinical observations. Brain 1999; 122 (Pt 12): 2353-2363
-
(1999)
Brain
, vol.122
, Issue.PART 12
, pp. 2353-2363
-
-
Andrews, T.C.1
Weeks, R.A.2
Turjanski, N.3
-
17
-
-
0029895292
-
Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease
-
Weeks RA, Piccini P, Harding AE, et al. Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease. Ann Neurol 1996; 40 (1): 49-54
-
(1996)
Ann Neurol
, vol.40
, Issue.1
, pp. 49-54
-
-
Weeks, R.A.1
Piccini, P.2
Harding, A.E.3
-
18
-
-
0032568517
-
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene
-
Cha JH, Kosinski CM, Kerner JA, et al. Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene. Proc Natl Acad Sci USA 1998; 95 (11): 6480-6485
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.11
, pp. 6480-6485
-
-
Cha, J.H.1
Kosinski, C.M.2
Kerner, J.A.3
-
19
-
-
0015790444
-
Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain
-
Perry TL, Hansen S, Kloster M. Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain. N Engl J Med 1973; 288 (7): 337-342
-
(1973)
N Engl J Med
, vol.288
, Issue.7
, pp. 337-342
-
-
Perry, T.L.1
Hansen, S.2
Kloster, M.3
-
20
-
-
62149136286
-
Functional imaging in Huntington's disease
-
Paulsen JS. Functional imaging in Huntington's disease. Exp Neurol 2009; 216 (2): 272-277
-
(2009)
Exp Neurol
, vol.216
, Issue.2
, pp. 272-277
-
-
Paulsen, J.S.1
-
21
-
-
0141432169
-
Changes in GAD67 mRNA expression evidenced by in situ hybridization in the brain of R6/2 transgenic mice
-
Gourfinkel-An I, Parain K, Hartmann A, et al. Changes in GAD67 mRNA expression evidenced by in situ hybridization in the brain of R6/2 transgenic mice. J Neuro-chem 2003; 86 (6): 1369-1378
-
(2003)
J Neuro-chem
, vol.86
, Issue.6
, pp. 1369-1378
-
-
Gourfinkel-An, I.1
Parain, K.2
Hartmann, A.3
-
22
-
-
0035180327
-
Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice
-
Nicniocaill B, Haraldsson B, Hansson O, et al. Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice. Eur J Neurosci 2001; 13 (1): 206-210
-
(2001)
Eur J Neurosci
, vol.13
, Issue.1
, pp. 206-210
-
-
Nicniocaill, B.1
Haraldsson, B.2
Hansson, O.3
-
23
-
-
0026684333
-
The epidemiology of Huntington's disease
-
Harper PS. The epidemiology of Huntington's disease. Hum Genet 1992; 89 (4): 365-376
-
(1992)
Hum Genet
, vol.89
, Issue.4
, pp. 365-376
-
-
Harper, P.S.1
-
24
-
-
0029098272
-
The epidemiology of Huntington's disease in Northern Ireland
-
Morrison PJ, Johnston WP, Nevin NC. The epidemiology of Huntington's disease in Northern Ireland. J Med Genet 1995; 32 (7): 524-530
-
(1995)
J Med Genet
, vol.32
, Issue.7
, pp. 524-530
-
-
Morrison, P.J.1
Johnston, W.P.2
Nevin, N.C.3
-
25
-
-
65649125624
-
Epidemiology of Huntington's disease in Slovenia
-
Peterlin B, Kobal J, Teran N, et al. Epidemiology of Huntington's disease in Slovenia. Acta Neurol Scand 2009; 119 (6): 371-375
-
(2009)
Acta Neurol Scand
, vol.119
, Issue.6
, pp. 371-375
-
-
Peterlin, B.1
Kobal, J.2
Teran, N.3
-
26
-
-
0024892247
-
The prevalence and patterns of care of Huntington's chorea in Grampian
-
Simpson SA, Johnston AW. The prevalence and patterns of care of Huntington's chorea in Grampian. Br J Psychiatry 1989; 155: 799-804
-
(1989)
Br J Psychiatry
, vol.155
, pp. 799-804
-
-
Simpson, S.A.1
Johnston, A.W.2
-
27
-
-
0025290717
-
Huntington's disease in Venezuela: 7 years of follow-up on symptomatic and asymptomatic individuals
-
Penney Jr JB, Young AB, Shoulson I, et al. Huntington's disease in Venezuela: 7 years of follow-up on symptomatic and asymptomatic individuals. Mov Disord 1990; 5 (2): 93-99
-
(1990)
Mov Disord
, vol.5
, Issue.2
, pp. 93-99
-
-
Penney Jr, J.B.1
Young, A.B.2
Shoulson, I.3
-
28
-
-
34250327141
-
Psychiatric and cognitive difficulties as indicators of juvenile hun-tington disease onset in 29 patients
-
Ribai P, Nguyen K, Hahn-Barma V, et al. Psychiatric and cognitive difficulties as indicators of juvenile hun-tington disease onset in 29 patients. Arch Neurol 2007; 64 (6): 813-819
-
(2007)
Arch Neurol
, vol.64
, Issue.6
, pp. 813-819
-
-
Ribai, P.1
Nguyen, K.2
Hahn-Barma, V.3
-
29
-
-
70449931956
-
Motor abnormalities in premanifest persons with Huntington's disease: The PREDICT-HD study
-
PREDICTHD Investigators of the Huntington Study Group Sep 15
-
Biglan KM, Ross CA, Langbehn DR, et al., PREDICTHD Investigators of the Huntington Study Group. Motor abnormalities in premanifest persons with Huntington's disease: the PREDICT-HD study. Mov Disord 2009 Sep 15; 24 (12): 1763-1772
-
(2009)
Mov Disord
, vol.24
, Issue.12
, pp. 1763-1772
-
-
Biglan, K.M.1
Ross, C.A.2
Langbehn, D.R.3
-
30
-
-
68249113963
-
TRACK-HD investigators. Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: Cross-sectional analysis of baseline data
-
Sep
-
Tabrizi SJ, Langbehn DR, Leavitt BR, et al., TRACK-HD investigators. Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data. Lancet Neurol 2009 Sep; 8 (9): 791-801
-
(2009)
Lancet Neurol
, vol.8
, Issue.9
, pp. 791-801
-
-
Tabrizi, S.J.1
Langbehn, D.R.2
Leavitt, B.R.3
-
31
-
-
33745865938
-
At risk for Huntington's disease: The PHAROS (Prospective Huntington at risk observational study) cohort enrolled
-
Huntington Study Group PHAROS Investigators (Shoulson I, primary author)
-
Huntington Study Group PHAROS Investigators (Shoulson I, primary author). At risk for Huntington's disease: the PHAROS (Prospective Huntington at risk observational study) cohort enrolled. Arch Neurol 2006; 63: 991-998
-
(2006)
Arch Neurol
, vol.63
, pp. 991-998
-
-
-
32
-
-
77949963765
-
-
Huntington Study Group. Cooperative Huntington's Observational Research Trial [ClinicalTrials.gov identifier NCT00313495]. US National Institutes of Health. Clinical Trials.gov [online] [Accessed 2010 Jan 26]
-
Huntington Study Group. Cooperative Huntington's Observational Research Trial [ClinicalTrials.gov identifier NCT00313495]. US National Institutes of Health. Clinical Trials.gov [online]. Available from URL: http://www.clini caltrials.gov [Accessed 2010 Jan 26]
-
-
-
-
33
-
-
33847715903
-
Verbal episodic memory declines prior to diagnosis in Huntington's disease
-
Predict-HD investigators of the Huntington Study Group Apr 9
-
Solomon AC, Stout JC, Johnson SA, et al., Predict-HD investigators of the Huntington Study Group. Verbal episodic memory declines prior to diagnosis in Huntington's disease. Neuropsychologia 2007 Apr 9; 45 (8): 1767-1776
-
(2007)
Neuropsychologia
, vol.45
, Issue.8
, pp. 1767-1776
-
-
Solomon, A.C.1
Stout, J.C.2
Johnson, S.A.3
-
34
-
-
34447620858
-
Beyond disgust: Impaired recognition of negative emotions prior to diagnosis in Huntington's disease
-
Predict-HD Investigators of the Huntington Study Group Jul
-
Johnson SA, Stout JC, Solomon AC, et al., Predict-HD Investigators of the Huntington Study Group. Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease. Brain 2007 Jul; 130 (Pt 7): 1732-1744
-
(2007)
Brain
, vol.130
, Issue.PART 7
, pp. 1732-1744
-
-
Johnson, S.A.1
Stout, J.C.2
Solomon, A.C.3
-
35
-
-
48249114740
-
Predict-HD Investigators and Coordinators of the Huntington Study Group. Detection of Huntington's disease decades before diagnosis: The Predict-HD study
-
Aug
-
Paulsen JS, Langbehn DR, Stout JC, et al., Predict-HD Investigators and Coordinators of the Huntington Study Group. Detection of Huntington's disease decades before diagnosis: the Predict-HD study. J Neurol Neurosurg Psychiatry 2008 Aug; 79 (8): 874-880
-
(2008)
J Neurol Neurosurg Psychiatry
, vol.79
, Issue.8
, pp. 874-880
-
-
Paulsen, J.S.1
Langbehn, D.R.2
Stout, J.C.3
-
36
-
-
36549036813
-
Psychiatric symptoms in Huntington's disease before diagnosis: The Predict-HD study
-
Predict-HD Investigators of the Huntington Study Group Dec 15
-
Duff K, Paulsen JS, Beglinger LJ, et al., Predict-HD Investigators of the Huntington Study Group. Psychiatric symptoms in Huntington's disease before diagnosis: the Predict-HD study. Biol Psychiatry 2007 Dec 15; 62 (12): 1341-1346
-
(2007)
Biol Psychiatry
, vol.62
, Issue.12
, pp. 1341-1346
-
-
Duff, K.1
Paulsen, J.S.2
Beglinger, L.J.3
-
37
-
-
85009332113
-
Unified Huntington's Disease Rating Scale: Reliability and consistency
-
Huntington Study Group
-
Huntington Study Group. Unified Huntington's Disease Rating Scale: reliability and consistency. Mov Disord 1996; 11 (2): 136-142
-
(1996)
Mov Disord
, vol.11
, Issue.2
, pp. 136-142
-
-
-
38
-
-
0032065590
-
Laboratory guidelines for Huntington disease genetic testing
-
The American College of Medical Genetics/American Society of Human Genetics Huntington Disease Genetic Testing Working Group. ACMG/ASHG statement
-
The American College of Medical Genetics/American Society of Human Genetics Huntington Disease Genetic Testing Working Group. ACMG/ASHG statement. Laboratory guidelines for Huntington disease genetic testing. Am J Hum Genet 1998; 62 (5): 1243-1247
-
(1998)
Am J Hum Genet
, vol.62
, Issue.5
, pp. 1243-1247
-
-
-
39
-
-
48649083048
-
Huntington's disease as caused by 34 CAG repeats
-
Andrich J, Arning L, Wieczorek S, et al. Huntington's disease as caused by 34 CAG repeats. Mov Disord 2008; 23 (6): 879-881
-
(2008)
Mov Disord
, vol.23
, Issue.6
, pp. 879-881
-
-
Andrich, J.1
Arning, L.2
Wieczorek, S.3
-
40
-
-
33847694688
-
Autopsy-proven Huntington's disease with 29 trinucleotide repeats
-
Kenney C, Powell S, Jankovic J. Autopsy-proven Huntington's disease with 29 trinucleotide repeats. Mov Disord 2007; 22 (1): 127-130
-
(2007)
Mov Disord
, vol.22
, Issue.1
, pp. 127-130
-
-
Kenney, C.1
Powell, S.2
Jankovic, J.3
-
41
-
-
0027261537
-
Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease
-
Snell RG, MacMillan JC, Cheadle JP, et al. Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease. Nat Genet 1993; 4 (4): 393-397
-
(1993)
Nat Genet
, vol.4
, Issue.4
, pp. 393-397
-
-
Snell, R.G.1
MacMillan, J.C.2
Cheadle, J.P.3
-
42
-
-
0027467546
-
Suicide risk in Huntington's disease
-
Di ML, Squitieri F, Napolitano G, et al. Suicide risk in Huntington's disease. J Med Genet 1993; 30 (4): 293-295
-
(1993)
J Med Genet
, vol.30
, Issue.4
, pp. 293-295
-
-
Di Ml Squitieri, F.1
Napolitano, G.2
-
43
-
-
41249096422
-
Symptomatic treatment of Huntington disease
-
Adam OR, Jankovic J. Symptomatic treatment of Huntington disease. Neurotherapeutics 2008; 5 (2): 181-197
-
(2008)
Neurotherapeutics
, vol.5
, Issue.2
, pp. 181-197
-
-
Adam, O.R.1
Jankovic, J.2
-
44
-
-
53049084348
-
The current clinical management of Huntington's disease
-
Phillips W, Shannon KM, Barker RA. The current clinical management of Huntington's disease. Mov Disord 2008; 23 (11): 1491-1504
-
(2008)
Mov Disord
, vol.23
, Issue.11
, pp. 1491-1504
-
-
Phillips, W.1
Shannon, K.M.2
Barker, R.A.3
-
45
-
-
52049085768
-
Pathophysiology of Huntington's disease: From huntingtin functions to potential treatments
-
Roze E, Saudou F, Caboche J. Pathophysiology of Huntington's disease: from huntingtin functions to potential treatments. Curr Opin Neurol 2008; 21 (4): 497-503
-
(2008)
Curr Opin Neurol
, vol.21
, Issue.4
, pp. 497-503
-
-
Roze, E.1
Saudou, F.2
Caboche, J.3
-
46
-
-
44449131447
-
Huntington's disease: From pathology and genetics to potential therapies
-
Imarisio S, Carmichael J, Korolchuk V, et al. Huntington's disease: from pathology and genetics to potential therapies. Biochem J 2008; 412: 191-209
-
(2008)
Biochem J
, vol.412
, pp. 191-209
-
-
Imarisio, S.1
Carmichael, J.2
Korolchuk, V.3
-
47
-
-
33846225133
-
Huntington's disease
-
Walker FO. Huntington's disease. Lancet 2007; 369 (9557): 218-228
-
(2007)
Lancet
, vol.369
, Issue.9557
, pp. 218-228
-
-
Walker, F.O.1
-
48
-
-
68249146267
-
Treatment of hyperkinetic movement disorders
-
Jankovic J. Treatment of hyperkinetic movement disorders. Lancet Neurol 2009; 8 (9): 844-856
-
(2009)
Lancet Neurol
, vol.8
, Issue.9
, pp. 844-856
-
-
Jankovic, J.1
-
49
-
-
33745759912
-
Pharmacological management of Huntington's disease: An evidence-based review
-
Bonelli RM, Wenning GK. Pharmacological management of Huntington's disease: an evidence-based review. Curr Pharm Des 2006; 12 (21): 2701-2720
-
(2006)
Curr Pharm des
, vol.12
, Issue.21
, pp. 2701-2720
-
-
Bonelli, R.M.1
Wenning, G.K.2
-
50
-
-
34147207888
-
Huntington's disease: Clinical characteristics, pathogenesis and therapies
-
Nakamura K, Aminoff MJ. Huntington's disease: clinical characteristics, pathogenesis and therapies. Drugs Today (Barc) 2007; 43 (2): 97-116
-
(2007)
Drugs Today (Barc)
, vol.43
, Issue.2
, pp. 97-116
-
-
Nakamura, K.1
Aminoff, M.J.2
-
51
-
-
30344476118
-
Pharmaceutical, cellular and genetic therapies for Huntington's disease
-
Handley OJ, Naji JJ, Dunnett SB, et al. Pharmaceutical, cellular and genetic therapies for Huntington's disease. Clin Sci (Lond) 2006; 110 (1): 73-88
-
(2006)
Clin Sci (Lond)
, vol.110
, Issue.1
, pp. 73-88
-
-
Handley, O.J.1
Naji, J.J.2
Dunnett, S.B.3
-
52
-
-
1842854595
-
A review of the treatment options for Huntington's disease
-
Bonelli RM, Hofmann P. A review of the treatment options for Huntington's disease. Expert Opin Pharmacother 2004; 5 (4): 767-776
-
(2004)
Expert Opin Pharmacother
, vol.5
, Issue.4
, pp. 767-776
-
-
Bonelli, R.M.1
Hofmann, P.2
-
53
-
-
0037286917
-
Therapeutic options for Huntington's disease
-
Grimbergen YA, Roos RA. Therapeutic options for Huntington's disease. Curr Opin Investig Drugs 2003; 4 (1): 51-54
-
(2003)
Curr Opin Investig Drugs
, vol.4
, Issue.1
, pp. 51-54
-
-
Grimbergen, Y.A.1
Roos, R.A.2
-
54
-
-
0020510988
-
Differential interactions of phencyclidine with tetrabenazine and reserpine affecting intraneuronal dopamine
-
Bagchi SP. Differential interactions of phencyclidine with tetrabenazine and reserpine affecting intraneuronal dopamine. Biochem Pharmacol 1983; 32 (19): 2851-2856
-
(1983)
Biochem Pharmacol
, vol.32
, Issue.19
, pp. 2851-2856
-
-
Bagchi, S.P.1
-
55
-
-
0021251068
-
Tetrabenazine-induced depletion of brain monoamines: Mechanism by which desmethylimipramine protects cortical norepine-phrine
-
Pettibone DJ, Pflueger AB, Totaro JA. Tetrabenazine-induced depletion of brain monoamines: mechanism by which desmethylimipramine protects cortical norepine-phrine. Eur J Pharmacol 1984; 102 (3-4): 431-436
-
(1984)
Eur J Pharmacol
, vol.102
, Issue.3-4
, pp. 431-436
-
-
Pettibone, D.J.1
Pflueger, A.B.2
Totaro, J.A.3
-
56
-
-
0023236626
-
Concentration-effect relationships of tetrabenazine and dihydrotetrabenazine in the rat
-
Mehvar R, Jamali F. Concentration-effect relationships of tetrabenazine and dihydrotetrabenazine in the rat. J Pharm Sci 1987; 76 (6): 461-465
-
(1987)
J Pharm Sci
, vol.76
, Issue.6
, pp. 461-465
-
-
Mehvar, R.1
Jamali, F.2
-
57
-
-
0029056219
-
Regional distribution of monoamine vesicular uptake sites in the mesencephalon of control subjects and patients with Parkinson's disease: A postmortem study using tritiated tetrabenazine
-
Thibaut F, Faucheux BA, Marquez J, et al. Regional distribution of monoamine vesicular uptake sites in the mesencephalon of control subjects and patients with Parkinson's disease: a postmortem study using tritiated tetrabenazine. Brain Res 1995; 692 (1-2): 233-243
-
(1995)
Brain Res
, vol.692
, Issue.1-2
, pp. 233-243
-
-
Thibaut, F.1
Faucheux, B.A.2
Marquez, J.3
-
58
-
-
33847694844
-
Short-term effects of tetrabenazine on chorea associated with Huntington's disease
-
Kenney C, Hunter C, Davidson A, et al. Short-term effects of tetrabenazine on chorea associated with Huntington's disease. Mov Disord 2007; 22 (1): 10-13
-
(2007)
Mov Disord
, vol.22
, Issue.1
, pp. 10-13
-
-
Kenney, C.1
Hunter, C.2
Davidson, A.3
-
59
-
-
0021288772
-
Reserpine binding to bovine chromaffin granule membranes Characterization and comparison with dihydrotetrabenazine binding
-
Scherman D, Henry JP. Reserpine binding to bovine chromaffin granule membranes. Characterization and comparison with dihydrotetrabenazine binding. Mol Pharmacol 1984; 25 (1): 113-122
-
(1984)
Mol Pharmacol
, vol.25
, Issue.1
, pp. 113-122
-
-
Scherman, D.1
Henry, J.P.2
-
60
-
-
0023093007
-
Pharmacokinetics of tetrabenazine and its major metabolite in man and rat Bioavailability and dose dependency studies
-
Mehvar R, Jamali F, Watson MW, et al. Pharmacokinetics of tetrabenazine and its major metabolite in man and rat. Bioavailability and dose dependency studies. Drug Metab Dispos 1987; 15 (2): 250-255
-
(1987)
Drug Metab Dispos
, vol.15
, Issue.2
, pp. 250-255
-
-
Mehvar, R.1
Jamali, F.2
Watson, M.W.3
-
61
-
-
0019801780
-
Determination of therapeutic plasma concentrations of tetrabenazine and an active metabolite by high-performance liquid chro-matography
-
Roberts MS, Watson HM, McLean S, et al. Determination of therapeutic plasma concentrations of tetrabenazine and an active metabolite by high-performance liquid chro-matography. J Chromatogr 1981; 226 (1): 175-182
-
(1981)
J Chromatogr
, vol.226
, Issue.1
, pp. 175-182
-
-
Roberts, M.S.1
Watson, H.M.2
McLean, S.3
-
62
-
-
0022647428
-
The pharmacokinetics of tetrabenazine and its hydroxy metabolite in patients treated for involuntary movement disorders
-
Roberts MS, McLean S, Millingen KS, et al. The pharmacokinetics of tetrabenazine and its hydroxy metabolite in patients treated for involuntary movement disorders. Eur J Clin Pharmacol 1986; 29 (6): 703-708
-
(1986)
Eur J Clin Pharmacol
, vol.29
, Issue.6
, pp. 703-708
-
-
Roberts, M.S.1
McLean, S.2
Millingen, K.S.3
-
63
-
-
33645798913
-
Tetrabenazine as antichorea therapy in Huntington disease: A randomized controlled trial
-
Huntington Study Group
-
Huntington Study Group. Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial. Neurology 2006; 66 (3): 366-372
-
(2006)
Neurology
, vol.66
, Issue.3
, pp. 366-372
-
-
-
64
-
-
0031029072
-
Long-term effects of tetrabenazine in hyperkinetic movement disorders
-
Jankovic J, Beach J. Long-term effects of tetrabenazine in hyperkinetic movement disorders. Neurology 1997; 48 (2): 358-362
-
(1997)
Neurology
, vol.48
, Issue.2
, pp. 358-362
-
-
Jankovic, J.1
Beach, J.2
-
65
-
-
33847731495
-
Long-term tolerability of tetrabenazine in the treatment of hyperkinetic movement disorders
-
Kenney C, Hunter C, Jankovic J. Long-term tolerability of tetrabenazine in the treatment of hyperkinetic movement disorders. Mov Disord 2007; 22 (2): 193-197
-
(2007)
Mov Disord
, vol.22
, Issue.2
, pp. 193-197
-
-
Kenney, C.1
Hunter, C.2
Jankovic, J.3
-
66
-
-
59849086625
-
The long-term effect of tetrabenazine in the management of Huntington disease
-
Fasano A, Cadeddu F, Guidubaldi A, et al. The long-term effect of tetrabenazine in the management of Huntington disease. Clin Neuropharmacol 2008; 31 (6): 313-318
-
(2008)
Clin Neuropharmacol
, vol.31
, Issue.6
, pp. 313-318
-
-
Fasano, A.1
Cadeddu, F.2
Guidubaldi, A.3
-
67
-
-
74549128476
-
Tetrabenazine as anti-chorea therapy in Huntington disease: An open-label continuation study
-
Huntington Study Group/Tetra-HD Investigators Dec 18
-
Huntington Study Group/Tetra-HD Investigators. Tetrabenazine as anti-chorea therapy in Huntington disease: an open-label continuation study. BMC Neurol 2009 Dec 18; 9 62.
-
(2009)
BMC Neurol
, vol.9
, pp. 62
-
-
-
68
-
-
0021175970
-
A double blind trial of sulpiride in Huntington's disease and tardive dyskinesia
-
Quinn N, Marsden CD. A double blind trial of sulpiride in Huntington's disease and tardive dyskinesia. J Neurol Neurosurg Psychiatry 1984; 47 (8): 844-847
-
(1984)
J Neurol Neurosurg Psychiatry
, vol.47
, Issue.8
, pp. 844-847
-
-
Quinn, N.1
Marsden, C.D.2
-
69
-
-
0021733679
-
Tiapride versus placebo: A double-blind comparative study in the management of Huntington's chorea
-
Deroover J, Baro F, Bourguignon RP, et al. Tiapride versus placebo: a double-blind comparative study in the management of Huntington's chorea. Curr Med Res Opin 1984; 9 (5): 329-338
-
(1984)
Curr Med Res Opin
, vol.9
, Issue.5
, pp. 329-338
-
-
Deroover, J.1
Baro, F.2
Bourguignon, R.P.3
-
70
-
-
0016799879
-
A double blind trial of lithium carbonate and haloperidol in Huntington's chorea
-
Leonard DP, Kidson MA, Brown JG, et al. A double blind trial of lithium carbonate and haloperidol in Huntington's chorea. Aust N Z J Psychiatry 1975; 9 (2): 115-118
-
(1975)
Aust N Z J Psychiatry
, vol.9
, Issue.2
, pp. 115-118
-
-
Leonard, D.P.1
Kidson, M.A.2
Brown, J.G.3
-
71
-
-
0023868584
-
Serum haloperidol concentration and choreiform movements in Hunting-ton's disease
-
Barr AN, Fischer JH, Koller WC, et al. Serum haloperidol concentration and choreiform movements in Hunting-ton's disease. Neurology 1988; 38 (1): 84-88
-
(1988)
Neurology
, vol.38
, Issue.1
, pp. 84-88
-
-
Barr, A.N.1
Fischer, J.H.2
Koller, W.C.3
-
74
-
-
0036276160
-
Olanzapine in Huntington's disease
-
Paleacu D, Anca M, Giladi N. Olanzapine in Huntington's disease. Acta Neurol Scand 2002; 105 (6): 441-444
-
(2002)
Acta Neurol Scand
, vol.105
, Issue.6
, pp. 441-444
-
-
Paleacu, D.1
Anca, M.2
Giladi, N.3
-
76
-
-
0033000665
-
The use of olanzapine for movement disorder in Huntington's disease: A first case report
-
Dipple HC. The use of olanzapine for movement disorder in Huntington's disease: a first case report. J Neurol Neurosurg Psychiatry 1999; 67 (1): 123-124
-
(1999)
J Neurol Neurosurg Psychiatry
, vol.67
, Issue.1
, pp. 123-124
-
-
Dipple, H.C.1
-
77
-
-
33746687898
-
Clinical experience with risperidone and memantine in the treatment of Huntington's disease
-
Cankurtaran ES, Ozalp E, Soygur H, et al. Clinical experience with risperidone and memantine in the treatment of Huntington's disease. J Natl Med Assoc 2006; 98 (8): 1353-1355
-
(2006)
J Natl Med Assoc
, vol.98
, Issue.8
, pp. 1353-1355
-
-
Cankurtaran, E.S.1
Ozalp, E.2
Soygur, H.3
-
78
-
-
0036038875
-
Risperidone in chorea and psychosis of Huntington's disease
-
Erdemoglu AK, Boratav C. Risperidone in chorea and psychosis of Huntington's disease. Eur J Neurol 2002; 9 (2): 182-183
-
(2002)
Eur J Neurol
, vol.9
, Issue.2
, pp. 182-183
-
-
Erdemoglu, A.K.1
Boratav, C.2
-
79
-
-
0031708158
-
Use of risperidone in psychosis associated with Huntington's disease
-
Madhusoodanan S, Brenner R. Use of risperidone in psychosis associated with Huntington's disease. Am J Geriatr Psychiatry 1998; 6 (4): 347-349
-
(1998)
Am J Geriatr Psychiatry
, vol.6
, Issue.4
, pp. 347-349
-
-
Madhusoodanan, S.1
Brenner, R.2
-
80
-
-
0030938246
-
Risperidone in treatment of choreoathetosis of Huntington's disease
-
Parsa MA, Szigethy E, Voci JM, et al. Risperidone in treatment of choreoathetosis of Huntington's disease. J Clin Psychopharmacol 1997; 17 (2): 134-135
-
(1997)
J Clin Psychopharmacol
, vol.17
, Issue.2
, pp. 134-135
-
-
Parsa, M.A.1
Szigethy, E.2
Voci, J.M.3
-
81
-
-
29544445190
-
Quetiapine in the treatment of behavioral disturbances in patients with Huntington's disease
-
Alpay M, Koroshetz WJ. Quetiapine in the treatment of behavioral disturbances in patients with Huntington's disease. Psychosomatics 2006; 47 (1): 70-72
-
(2006)
Psychosomatics
, vol.47
, Issue.1
, pp. 70-72
-
-
Alpay, M.1
Koroshetz, W.J.2
-
82
-
-
3042733763
-
Quetiapine in the management of psychosis secondary to Huntington's disease: A case report
-
Seitz DP, Millson RC. Quetiapine in the management of psychosis secondary to Huntington's disease: a case report. Can J Psychiatry 2004; 49 (6): 413
-
(2004)
Can J Psychiatry
, vol.49
, Issue.6
, pp. 413
-
-
Seitz, D.P.1
Millson, R.C.2
-
83
-
-
0036041559
-
Quetiapine in Huntington's disease: A first case report
-
Bonelli RM, Niederwieser G. Quetiapine in Huntington's disease: a first case report. J Neurol 2002; 249 (8): 1114-1115
-
(2002)
J Neurol
, vol.249
, Issue.8
, pp. 1114-1115
-
-
Bonelli, R.M.1
Niederwieser, G.2
-
84
-
-
0030790234
-
Clozapine versus placebo in Huntington's disease: A double blind randomised comparative study
-
van Vugt JP, Siesling S, Vergeer M, et al. Clozapine versus placebo in Huntington's disease: a double blind randomised comparative study. J Neurol Neurosurg Psychiatry 1997; 63 (1): 35-39
-
(1997)
J Neurol Neurosurg Psychiatry
, vol.63
, Issue.1
, pp. 35-39
-
-
Van Vugt, J.P.1
Siesling, S.2
Vergeer, M.3
-
85
-
-
70449710919
-
Aripiprazole in the treatment of Huntington's disease: A case series
-
Ciammola A, Sassone J, Colciago C, et al. Aripiprazole in the treatment of Huntington's disease: a case series. Neuropsychiatr Dis Treat 2009; 5: 1-4
-
(2009)
Neuropsychiatr Dis Treat
, vol.5
, pp. 1-4
-
-
Ciammola, A.1
Sassone, J.2
Colciago, C.3
-
86
-
-
61449249292
-
Treatment of the symptoms of Huntington's disease: Preliminary results comparing aripiprazole and tetrabenazine
-
Brusa L, Orlacchio A, Moschella V, et al. Treatment of the symptoms of Huntington's disease: preliminary results comparing aripiprazole and tetrabenazine. Mov Disord 2009; 24 (1): 126-129
-
(2009)
Mov Disord
, vol.24
, Issue.1
, pp. 126-129
-
-
Brusa, L.1
Orlacchio, A.2
Moschella, V.3
-
87
-
-
51349084524
-
Aripiprazole effects on psychosis and chorea in a patient with Huntington's disease
-
Lin WC, Chou YH. Aripiprazole effects on psychosis and chorea in a patient with Huntington's disease. Am J Psychiatry 2008; 165 (9): 1207-1208
-
(2008)
Am J Psychiatry
, vol.165
, Issue.9
, pp. 1207-1208
-
-
Lin, W.C.1
Chou, Y.H.2
-
88
-
-
0036757043
-
Amantadine in Huntington's disease: Open-label video-blinded study
-
Lucetti C, Gambaccini G, Bernardini S, et al. Amantadine in Huntington's disease: open-label video-blinded study. Neurol Sci 2002; 23 Suppl. 2: S83-4
-
(2002)
Neurol Sci
, vol.23
, Issue.SUPPL. 2
-
-
Lucetti, C.1
Gambaccini, G.2
Bernardini, S.3
-
89
-
-
0023231127
-
Adverse behavioral effects of amantadine therapy in Huntington's disease
-
Stewart JT. Adverse behavioral effects of amantadine therapy in Huntington's disease. South Med J 1987; 80 (10): 1324-1325
-
(1987)
South Med J
, vol.80
, Issue.10
, pp. 1324-1325
-
-
Stewart, J.T.1
-
90
-
-
0345600893
-
Dosage effects of riluzole in Huntington's disease: A multicenter placebo-controlled study
-
Dosage effects of riluzole in Huntington's disease: a multicenter placebo-controlled study. Neurology 2003; 61 (11): 1551-1556
-
(2003)
Neurology
, vol.61
, Issue.11
, pp. 1551-1556
-
-
-
91
-
-
34948838383
-
Riluzole in Huntington's disease: A 3-year, randomized controlled study
-
Landwehrmeyer GB, Dubois B, de Yebenes JG, et al. Riluzole in Huntington's disease: a 3-year, randomized controlled study. Ann Neurol 2007; 62 (3): 262-272
-
(2007)
Ann Neurol
, vol.62
, Issue.3
, pp. 262-272
-
-
Landwehrmeyer, G.B.1
Dubois, B.2
De Yebenes, J.G.3
-
92
-
-
0017252399
-
Clonazepam in the treatment of choreiform activity
-
Peiris JB, Boralessa H, Lionel ND. Clonazepam in the treatment of choreiform activity. Med J Aust 1976; 1 (8): 225-227
-
(1976)
Med J Aust
, vol.1
, Issue.8
, pp. 225-227
-
-
Peiris, J.B.1
Boralessa, H.2
Lionel, N.D.3
-
93
-
-
0020612106
-
Acute treatment of Huntington's chorea with lisuride
-
Frattola L, Albizzati MG, Alemani A, et al. Acute treatment of Huntington's chorea with lisuride. J Neurol Sci 1983; 59 (2): 247-253
-
(1983)
J Neurol Sci
, vol.59
, Issue.2
, pp. 247-253
-
-
Frattola, L.1
Albizzati, M.G.2
Alemani, A.3
-
94
-
-
38549166606
-
Short-term continuous infusion of apomorphine hydrochloride for treatment of Huntington's chorea: A double blind, randomized crossover trial
-
Vitale C, Marconi S, Di ML, et al. Short-term continuous infusion of apomorphine hydrochloride for treatment of Huntington's chorea: a double blind, randomized crossover trial. Mov Disord 2007; 22 (16): 2359-2364
-
(2007)
Mov Disord
, vol.22
, Issue.16
, pp. 2359-2364
-
-
Vitale, C.1
Marconi Di S, M.L.2
-
95
-
-
0018100179
-
Apomorphine hydrochloride-induced improvement in Huntington's chorea: Stimulation of dopamine receptor
-
Corsini GU, Onali P, Masala C, et al. Apomorphine hydrochloride-induced improvement in Huntington's chorea: stimulation of dopamine receptor. Arch Neurol 1978; 35 (1): 27-30
-
(1978)
Arch Neurol
, vol.35
, Issue.1
, pp. 27-30
-
-
Corsini, G.U.1
Onali, P.2
Masala, C.3
-
96
-
-
0016158978
-
Huntington's chorea: The rigid form (Westphal variant) treated with levodopa
-
Low PA, Allsop JL, Halmagyi GM. Huntington's chorea: the rigid form (Westphal variant) treated with levodopa. Med J Aust 1974; 1 (11): 393-394
-
(1974)
Med J Aust
, vol.1
, Issue.11
, pp. 393-394
-
-
Low, P.A.1
Allsop, J.L.2
Halmagyi, G.M.3
-
97
-
-
0015691076
-
Huntington's chorea-the rigid form (Westphal variant) treated with l-DOPA: A case report
-
Low PA, Allsop JL. Huntington's chorea-the rigid form (Westphal variant) treated with l-DOPA: a case report. Proc Aust Assoc Neurol 1973; 10 (0): 45-46
-
(1973)
Proc Aust Assoc Neurol
, vol.10
, Issue.0
, pp. 45-46
-
-
Low, P.A.1
Allsop, J.L.2
-
98
-
-
3042590648
-
Amantadine in the akinetic-rigid variant of Huntington's disease
-
Magnet MK, Bonelli RM, Kapfhammer HP. Amantadine in the akinetic-rigid variant of Huntington's disease. Ann Pharmacother 2004; 38 (7-8): 1194-1196
-
(2004)
Ann Pharmacother
, vol.38
, Issue.7-8
, pp. 1194-1196
-
-
Magnet, M.K.1
Bonelli, R.M.2
Kapfhammer, H.P.3
-
99
-
-
0036182828
-
Pramipexole ameliorates neurologic and psychiatric symptoms in a Westphal variant of Huntington's disease
-
Bonelli RM, Niederwieser G, Diez J, et al. Pramipexole ameliorates neurologic and psychiatric symptoms in a Westphal variant of Huntington's disease. Clin Neuro-pharmacol 2002; 25 (1): 58-60
-
(2002)
Clin Neuro-pharmacol
, vol.25
, Issue.1
, pp. 58-60
-
-
Bonelli, R.M.1
Niederwieser, G.2
Diez, J.3
-
100
-
-
0343340024
-
Bruxism in Huntington's disease
-
Tan EK, Jankovic J, Ondo W. Bruxism in Huntington's disease. Mov Disord 2000; 15 (1): 171-173
-
(2000)
Mov Disord
, vol.15
, Issue.1
, pp. 171-173
-
-
Tan, E.K.1
Jankovic, J.2
Ondo, W.3
-
101
-
-
2342598416
-
Experimental therapeutics in transgenic mouse models of Huntington's disease
-
Beal MF, Ferrante RJ. Experimental therapeutics in transgenic mouse models of Huntington's disease. Nat Rev Neurosci 2004; 5 (5): 373-384
-
(2004)
Nat Rev Neurosci
, vol.5
, Issue.5
, pp. 373-384
-
-
Beal, M.F.1
Ferrante, R.J.2
-
102
-
-
18844447024
-
Translating therapies for Huntington's disease from genetic animal models to clinical trials
-
Hersch SM, Ferrante RJ. Translating therapies for Huntington's disease from genetic animal models to clinical trials. NeuroRx 2004; 1 (3): 298-306
-
(2004)
NeuroRx
, vol.1
, Issue.3
, pp. 298-306
-
-
Hersch, S.M.1
Ferrante, R.J.2
-
103
-
-
33644927838
-
Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG
-
Hersch SM, Gevorkian S, Marder K, et al. Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG. Neurology 2006; 66 (2): 250-252
-
(2006)
Neurology
, vol.66
, Issue.2
, pp. 250-252
-
-
Hersch, S.M.1
Gevorkian, S.2
Marder, K.3
-
104
-
-
85009226418
-
A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease
-
Huntington Study Group
-
Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001; 57 (3): 397-404
-
(2001)
Neurology
, vol.57
, Issue.3
, pp. 397-404
-
-
-
105
-
-
33750837262
-
Nabilone could treat chorea and irritability in Huntington's disease
-
Curtis A, Rickards H. Nabilone could treat chorea and irritability in Huntington's disease. J Neuropsychiatry Clin Neurosci 2006; 18 (4): 553-554
-
(2006)
J Neuropsychiatry Clin Neurosci
, vol.18
, Issue.4
, pp. 553-554
-
-
Curtis, A.1
Rickards, H.2
-
106
-
-
0025837207
-
Controlled clinical trial of cannabidiol in Huntington's disease
-
Consroe P, Laguna J, Allender J, et al. Controlled clinical trial of cannabidiol in Huntington's disease. Pharmacol Biochem Behav 1991; 40 (3): 701-708
-
(1991)
Pharmacol Biochem Behav
, vol.40
, Issue.3
, pp. 701-708
-
-
Consroe, P.1
Laguna, J.2
Allender, J.3
-
107
-
-
0345237253
-
Nabilone increases choreatic movements in Huntington's disease
-
Muller-Vahl KR, Schneider U, Emrich HM. Nabilone increases choreatic movements in Huntington's disease. Mov Disord 1999; 14 (6): 1038-1040
-
(1999)
Mov Disord
, vol.14
, Issue.6
, pp. 1038-1040
-
-
Muller-Vahl, K.R.1
Schneider, U.2
Emrich, H.M.3
-
108
-
-
70049091196
-
Therapeutic interventions for disease progression in Huntington's disease
-
Mestre T, Ferreira J, Coelho MM, et al. Therapeutic interventions for disease progression in Huntington's disease. Cochrane Database Syst Rev 2009; (3): CD006455
-
(2009)
Cochrane Database Syst Rev
, vol.3
-
-
Mestre, T.1
Ferreira, J.2
Coelho, M.M.3
-
109
-
-
77950018633
-
-
Massachusetts General Hospital. Creatine Safety and Tolerability in Premanifest HD [ClinicalTrials.gov identifier NCT00592995]. US National Institutes of Health. Clinical Trials.gov [online] [Accessed 2010 Jan 26]
-
Massachusetts General Hospital. Creatine Safety and Tolerability in Premanifest HD [ClinicalTrials.gov identifier NCT00592995]. US National Institutes of Health. Clinical Trials.gov [online]. Available from URL: http:// www.clinicaltrials.gov [Accessed 2010 Jan 26]
-
-
-
-
110
-
-
41249101172
-
Neuroprotection for Huntington's disease: Ready, set, slow
-
Hersch SM, Rosas HD. Neuroprotection for Huntington's disease: ready, set, slow. Neurotherapeutics 2008; 5 (2): 226-236
-
(2008)
Neurotherapeutics
, vol.5
, Issue.2
, pp. 226-236
-
-
Hersch, S.M.1
Rosas, H.D.2
-
111
-
-
0032693984
-
Long-lasting improvement following (-)-OSU6162 in a patient with Huntington's disease
-
Tedroff J, Ekesbo A, Sonesson C, et al. Long-lasting improvement following (-)-OSU6162 in a patient with Huntington's disease. Neurology 1999; 53 (7): 1605-1606
-
(1999)
Neurology
, vol.53
, Issue.7
, pp. 1605-1606
-
-
Tedroff, J.1
Ekesbo, A.2
Sonesson, C.3
-
112
-
-
61449249687
-
Randomized controlled trial of ethyl-eicosapentaenoic acid in Huntington disease: The TREND-HD study
-
Huntington Study Group TREND-HD Investigators
-
Huntington Study Group TREND-HD Investigators. Randomized controlled trial of ethyl-eicosapentaenoic acid in Huntington disease: the TREND-HD study. Arch Neurol 2008; 65 (12): 1582-1589
-
(2008)
Arch Neurol
, vol.65
, Issue.12
, pp. 1582-1589
-
-
-
113
-
-
77949970968
-
PHEND-HD: A safety, tolerability, and biomarker study of phenylbutyrate in symptomatic HD [abstract]
-
Huntington Study Group
-
Huntington Study Group. PHEND-HD: a safety, tolerability, and biomarker study of phenylbutyrate in symptomatic HD [abstract]. Neurotherapeutics 2008; 5 (2): 363
-
(2008)
Neurotherapeutics
, vol.5
, Issue.2
, pp. 363
-
-
-
114
-
-
77950009211
-
A phase 2 trial of minocycline in Huntington's disease [abstract]
-
Huntington Study Group
-
Huntington Study Group. A phase 2 trial of minocycline in Huntington's disease [abstract]. Mov Disord 2009; 24 Suppl. 1: S164
-
(2009)
Mov Disord
, vol.24
, Issue.SUPPL. 1
-
-
-
115
-
-
65549091910
-
Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases
-
Yang L, Calingasan NY, Wille EJ, et al. Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases. J Neurochem 2009; 109 (5): 1427-1439
-
(2009)
J Neurochem
, vol.109
, Issue.5
, pp. 1427-1439
-
-
Yang, L.1
Calingasan, N.Y.2
Wille, E.J.3
-
116
-
-
41549114279
-
The role of autophagylysosome pathway in neurodegeneration associated with Parkinson's disease
-
Pan T, Kondo S, Le W, et al. The role of autophagylysosome pathway in neurodegeneration associated with Parkinson's disease. Brain 2008; 131 (Pt 8): 1969-1978
-
(2008)
Brain
, vol.131
, Issue.PART 8
, pp. 1969-1978
-
-
Pan, T.1
Kondo Le S, W.2
-
117
-
-
44049085489
-
Therapeutic potential of fluoxetine in neurological disorders
-
Mostert JP, Koch MW, Heerings M, et al. Therapeutic potential of fluoxetine in neurological disorders. CNS Neurosci Ther 2008; 14 (2): 153-164
-
(2008)
CNS Neurosci Ther
, vol.14
, Issue.2
, pp. 153-164
-
-
Mostert, J.P.1
Koch, M.W.2
Heerings, M.3
-
118
-
-
77949937002
-
-
US National Institutes of Health. ClinicalTrials.gov [online] [Accessed 2010 Jan 26]
-
US National Institutes of Health. ClinicalTrials.gov [online]. Available from URL http://www.clinicaltrials.gov [Accessed 2010 Jan 26]
-
-
-
-
119
-
-
76149084493
-
A randomized placebo-controlled trial of latrepirdine in Huntington disease
-
Kieburtz K, McDermott MP, Voss TS, et al. A randomized, placebo-controlled trial of latrepirdine in Huntington disease. Arch Neurol 2010; 67 (2): 154-160
-
(2010)
Arch Neurol
, vol.67
, Issue.2
, pp. 154-160
-
-
Kieburtz, K.1
McDermott, M.P.2
Voss, T.S.3
-
120
-
-
58149343340
-
Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease
-
Wang X, Zhu S, Pei Z, et al. Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease. J Neurosci 2008; 28 (38): 9473-9485
-
(2008)
J Neurosci
, vol.28
, Issue.38
, pp. 9473-9485
-
-
Wang, X.1
Zhu, S.2
Pei, Z.3
-
121
-
-
33745003424
-
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin
-
Graham RK, Deng Y, Slow EJ, et al. Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin. Cell 2006; 125 (6): 1179-1191
-
(2006)
Cell
, vol.125
, Issue.6
, pp. 1179-1191
-
-
Graham, R.K.1
Deng, Y.2
Slow, E.J.3
-
122
-
-
34249715853
-
Huntingtin interacting proteins are genetic modifiers of neurodegen-eration
-
May 11
-
Kaltenbach LS, Romero E, Becklin RR, et al. Huntingtin interacting proteins are genetic modifiers of neurodegen-eration. PLoS Genet 2007 May 11; 3 (5): e82
-
(2007)
PLoS Genet
, vol.3
, Issue.5
-
-
Kaltenbach, L.S.1
Romero, E.2
Becklin, R.R.3
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