PI 3-kinase regulation of dopamine uptake

Journal of Neurochemistry

Volumn 81, Issue 4, 2002, Pages 859-869

  Carvelli, Lucia ^a   Morón, José A ^a,g   Kahlig, Kristopher M ^a   Ferrer, Jasmine V ^d   Sen, Namita ^d   Lechleiter, James D ^a   Leeb Lundberg, L M Fredrik ^b   Merrill, Gerald ^e   Lafer, Eileen M ^b   Ballou, Lisa M ^g   Shippenberg, Toni S ^c   Javitch, Jonathan A ^a,d   Lin, Richard Z ^a,f   Galli, Aurelio ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^d Brooke Army Medical Center ^*  (United States)

^e BROOKE ARMY MEDICAL CENTER   (United States)

^f SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^g NONE

Author keywords

Amphetamine; Dopamin transporter; Insulin; P1 3 kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AMPHETAMINE; DOPAMINE; DOPAMINE RECEPTOR; DOPAMINE TRANSPORTER; DYNAMIN; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; CYTOSOL; DIABETES MELLITUS; DOPAMINE UPTAKE; ENZYME ACTIVITY; ENZYME REGULATION; HYPOINSULINEMIA; INTERNALIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR SENSITIVITY; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMPHETAMINE; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE; CHROMONES; CORPUS STRIATUM; CYTOSOL; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DYNAMIN I; DYNAMINS; ENZYME INHIBITORS; GENES, DOMINANT; GTP PHOSPHOHYDROLASES; HUMANS; INSULIN; KIDNEY; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MORPHOLINES; NERVE TISSUE PROTEINS; PROTEIN TRANSPORT; RATS; RECOMBINANT FUSION PROTEINS; SYNAPTOSOMES; TRANSFECTION;

ANIMALIA;

EID: 0036316735     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00892.x     Document Type: Article

References (52)

1. Acute regulation of norepinephrine transport: I. Protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells
2. Trafficking-dependent and -independent pathways of neurotransmitter transporter regulation differentially involving p38 mitogen-activated protein kinase revealed in studies of insulin modulation of norepinephrine transport in SK-N-SH cells
3. Differential permeability of the blood-brain barrier to two pancreatic peptides: Insulin and amylin
4. The IGF-I receptor in cell growth, transformation and apoptosis
5. Protein kinase A activity may kinetically upregulate the striatal transporter for dopamine
6. Neurotransmitter transporters: Regulators of function and functional regulation
7. Changes in insulin-like growth factor 1 receptor density after transient cerebral ischemia in the rat. Lack of protection against ischemic brain damage following injection of insulin-like growth factor 1
8. Biogenic amine transporters: Regulation in flux
9. Insulin inhibits specific norepinephrine uptake in neuronal cultures from rat brain
10. Hypoinsulinemia may mediate the lowering of self-stimulation thresholds by food restriction and streptozotocin-induced diabetes
11. Insulin action and the insulin signaling network
12. Immunocytochemical localization of the dopamine transporter in human brain
13. The dopamine transporter: Immunochemical characterization and localization in brain
14. Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin
15. Induction of mutant dynamin specifically blocks endocytic coated vesicle formation
16. Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters
17. Multiple signaling pathways regulate cell surface expression and activity of the excitatory amino acid carrier 1 subtype of Glu transporter in C6 glioma
18. Protein tyrosine kinase inhibitors alter human dopamine transporter activity in Xenopus oocytes
19. Insulin signaling regulating the trafficking and plasma membrane fusion of GLUT4-containing intracellular vesicles
20. Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter
21. Endocrine regulation of neurotransmitter transporters
22. Inactivation of the dopamine transporter reveals essential roles of dopamine in the control of locomotion, psychostimulant response, and pituitary function
23. Molecular characterization of the dopamine transporter
24. Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter
25. The tonic/phasic model of dopamine system regulation: Its relevance for understanding how stimulant abuse can alter basal ganglia function
26. Addiction to cocaine and amphetamine
27. Insulin resistance, diabetes, and the insulin-regulated trafficking of GLUT-4
28. Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter
29. Roles of PI 3-kinase and Ras on insulin-stimulated glucose transport in 3T3-L1 adipocytes
30. Overexpression of catalytic subunit p110alpha of phosphatidylinositol 3-kinase increases glucose transport activity with translocation of glucose transporters in 3T3-L1 adipocytes
31. Functional regulation of gamma-aminobutyric acid transporters by direct tyrosine phosphorylation
32. Membrane trafficking of neurotransmitter transporters in the regulation of synaptic transmission
33. Levels of insulin in the brains of rats modified by chronic administration of amphetamine, haloperidol and sulpiride
34. Further analysis of the resistance of the diabetic rat to d-amphetamine
35. Dopamine D2 receptor regulation of the dopamine transporter expressed in Xenopus laevis oocytes is voltage-independent
36. Membrane trafficking regulates the activity of the human dopamine transporter
37. Food deprivation decreases mRNA and activity of the rat dopamine transporter
38. Withdrawal of repeated intravenous infusions of cocaine persistently reduces binding to dopamine transporters in the nucleus accumbens of Lewis rats
39. Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter
40. Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression
41. Insulin receptors in the brain: Structural and physiological characterization
42. Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants
43. Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein
44. 3H]spiroperidol
45. Effects of the experimental diabetes on dopamine D1 receptor-mediated locomotor-enhancing activity in mice
46. Amphetamine-induced loss of human dopamine transporter activity: An internalization-dependent and cocaine-sensitive mechanism
47. Insulin receptors and insulin action in the brain: Review and ssclinical implications
48. Relationship between an altered membrane form and a low affinity form of the beta-adrenergic receptor occurring during catecholamine-induced desensitization. Evidence for receptor internalization
49. Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes
50. Regulation of the functional activity of the human dopamine transporter by protein kinase C
51. Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization
52. Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes