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Volumn 34, Issue 5, 2015, Pages 432-444

Beyond TLR Signaling - The Role of SARM in Antiviral Immune Defense, Apoptosis & Development

Author keywords

antiviral; apoptosis; cell death; innate immunity; TLR adaptors; TLR signaling pathways

Indexed keywords

PROTEIN; STERILE ALPHA AND ARMADILLO MOTIF CONTAINING PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 2; UNCLASSIFIED DRUG; ARMADILLO DOMAIN PROTEIN; CYTOSKELETON PROTEIN; SARM1 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 84941881013     PISSN: 08830185     EISSN: 15635244     Source Type: Journal    
DOI: 10.3109/08830185.2015.1065826     Document Type: Review
Times cited : (29)

References (75)
  • 1
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006;124(4):783-801.
    • (2006) Cell , vol.124 , Issue.4 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 2
    • 78751560494 scopus 로고    scopus 로고
    • Pathogen recognition by the innate immune system
    • Kumar H, Kawai T, Akira S. Pathogen recognition by the innate immune system. Int Rev Immunol 2011;30(1):16-34.
    • (2011) Int Rev Immunol , vol.30 , Issue.1 , pp. 16-34
    • Kumar, H.1    Kawai, T.2    Akira, S.3
  • 3
    • 0028038426 scopus 로고
    • MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation
    • Germain RN. MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell 1994;76(2):287-299.
    • (1994) Cell , vol.76 , Issue.2 , pp. 287-299
    • Germain, R.N.1
  • 4
    • 0035367786 scopus 로고    scopus 로고
    • A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans
    • Mink M, et al. A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans. Genomics 2001;74(2):234-244.
    • (2001) Genomics , vol.74 , Issue.2 , pp. 234-244
    • Mink, M.1
  • 5
    • 0035399769 scopus 로고    scopus 로고
    • Toll receptors in innate immunity
    • Imler JL, Hoffmann JA. Toll receptors in innate immunity. Trends Cell Biol 2001;11(7):304-311.
    • (2001) Trends Cell Biol , vol.11 , Issue.7 , pp. 304-311
    • Imler, J.L.1    Hoffmann, J.A.2
  • 6
    • 77955383770 scopus 로고    scopus 로고
    • DAMPening inflammation by modulating TLR signalling
    • Piccinini AM, Midwood KS. DAMPening inflammation by modulating TLR signalling. Mediat Inflamm 2010;2010.
    • (2010) Mediat Inflamm , vol.2010
    • Piccinini, A.M.1    Midwood, K.S.2
  • 7
    • 48149096398 scopus 로고    scopus 로고
    • HMGB1: Endogenous danger signaling
    • Klune JR, et al. HMGB1: endogenous danger signaling.MolMed 2008;14(7-8):476-484.
    • (2008) MolMed , vol.14 , Issue.7-8 , pp. 476-484
    • Klune, J.R.1
  • 8
    • 34948900275 scopus 로고    scopus 로고
    • Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock
    • Vogl T, et al. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. NatMed 2007;13(9):1042-19.
    • (2007) NatMed , vol.13 , Issue.9 , pp. 1042-1119
    • Vogl, T.1
  • 9
    • 58149310977 scopus 로고    scopus 로고
    • Fatty acid-induced induction of Toll-like receptor-4/nuclear factorkappaB pathway in adipocytes links nutritional signalling with innate immunity
    • Schaeffler A, et al. Fatty acid-induced induction of Toll-like receptor-4/nuclear factorkappaB pathway in adipocytes links nutritional signalling with innate immunity. Immunology 2009;126(2):233-245.
    • (2009) Immunology , vol.126 , Issue.2 , pp. 233-245
    • Schaeffler, A.1
  • 10
    • 0037094084 scopus 로고    scopus 로고
    • Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4
    • Johnson GB, et al. Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4. J Immunol 2002;168(10):5233-5239.
    • (2002) J Immunol , vol.168 , Issue.10 , pp. 5233-5239
    • Johnson, G.B.1
  • 11
    • 1842477469 scopus 로고    scopus 로고
    • mRNA is an endogenous ligand for Toll-like receptor 3
    • Kariko K, et al. mRNA is an endogenous ligand for Toll-like receptor 3. J Biol Chem 2004;279(13):12542-12550.
    • (2004) J Biol Chem , vol.279 , Issue.13 , pp. 12542-12550
    • Kariko, K.1
  • 12
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill LA, Bowie AG. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 2007;7(5):353-564.
    • (2007) Nat Rev Immunol , vol.7 , Issue.5 , pp. 353-564
    • O'Neill, L.A.1    Bowie, A.G.2
  • 13
    • 3142654210 scopus 로고    scopus 로고
    • Inferences, questions and possibilities in Toll-like receptor signalling
    • Beutler B. Inferences, questions and possibilities in Toll-like receptor signalling. Nature 2004;430(6996):257-263.
    • (2004) Nature , vol.430 , Issue.6996 , pp. 257-263
    • Beutler, B.1
  • 14
    • 0034597766 scopus 로고    scopus 로고
    • Structuralbasis for signal transductionby theToll/interleukin-1 receptordomains
    • XuY, et al. Structuralbasis for signal transductionby theToll/interleukin-1 receptordomains.Nature 2000;408(6808):111-115.
    • (2000) Nature , vol.408 , Issue.6808 , pp. 111-115
    • Xu, Y.1
  • 15
    • 40949134086 scopus 로고    scopus 로고
    • TRAMcouples endocytosis of Toll-like receptor 4 to the induction of interferon-beta
    • Kagan JC, et al. TRAMcouples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat Immunol 2008;9(4):361-368.
    • (2008) Nat Immunol , vol.9 , Issue.4 , pp. 361-368
    • Kagan, J.C.1
  • 16
    • 0035817925 scopus 로고    scopus 로고
    • Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
    • Fitzgerald KA, et al. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 2001;413(6851):78-83.
    • (2001) Nature , vol.413 , Issue.6851 , pp. 78-83
    • Fitzgerald, K.A.1
  • 17
    • 0035555301 scopus 로고    scopus 로고
    • TIRAP: An adapter molecule in the Toll signaling pathway
    • Horng T, Barton GM, Medzhitov R. TIRAP: an adapter molecule in the Toll signaling pathway. Nat Immunol 2001;2(9):835-841.
    • (2001) Nat Immunol , vol.2 , Issue.9 , pp. 835-841
    • Horng, T.1    Barton, G.M.2    Medzhitov, R.3
  • 18
    • 0037153191 scopus 로고    scopus 로고
    • Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
    • Yamamoto M, et al. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 2002;420(6913):324-329.
    • (2002) Nature , vol.420 , Issue.6913 , pp. 324-329
    • Yamamoto, M.1
  • 19
    • 0042591216 scopus 로고    scopus 로고
    • TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling
    • Bin LH, Xu LG, Shu HB. TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. J Biol Chem 2003;278(27):24526-24532.
    • (2003) J Biol Chem , vol.278 , Issue.27 , pp. 24526-24532
    • Bin, L.H.1    Xu, L.G.2    Shu, H.B.3
  • 20
    • 0141959224 scopus 로고    scopus 로고
    • LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF
    • Fitzgerald KA, et al. LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF. J ExpMed 2003;198(7):1043-1055.
    • (2003) J ExpMed , vol.198 , Issue.7 , pp. 1043-1055
    • Fitzgerald, K.A.1
  • 21
    • 0043176281 scopus 로고    scopus 로고
    • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
    • Yamamoto M, et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 2003;301(5633):640-643.
    • (2003) Science , vol.301 , Issue.5633 , pp. 640-643
    • Yamamoto, M.1
  • 22
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • Kawai T, et al. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 1999;11(1):115-122.
    • (1999) Immunity , vol.11 , Issue.1 , pp. 115-122
    • Kawai, T.1
  • 23
    • 70350026642 scopus 로고    scopus 로고
    • A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling
    • Nagpal K, et al. A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling. J Biol Chem 2009;284(38):25742-25748.
    • (2009) J Biol Chem , vol.284 , Issue.38 , pp. 25742-25748
    • Nagpal, K.1
  • 24
    • 0037153130 scopus 로고    scopus 로고
    • The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
    • Horng T, et al. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 2002;420(6913):329-333.
    • (2002) Nature , vol.420 , Issue.6913 , pp. 329-333
    • Horng, T.1
  • 25
    • 0347480221 scopus 로고    scopus 로고
    • Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish
    • Meijer AH, et al. Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish.Mol Immunol 2004;40(11):773-783.
    • (2004) Mol Immunol , vol.40 , Issue.11 , pp. 773-783
    • Meijer, A.H.1
  • 26
    • 0346849669 scopus 로고    scopus 로고
    • Toll-like receptor gene family and TIR-domain adapters in Danio rerio
    • Jault C, Pichon L, Chluba J. Toll-like receptor gene family and TIR-domain adapters in Danio rerio. Mol Immunol 2004;40(11):759-771.
    • (2004) Mol Immunol , vol.40 , Issue.11 , pp. 759-771
    • Jault, C.1    Pichon, L.2    Chluba, J.3
  • 27
    • 2442664007 scopus 로고    scopus 로고
    • TLR-independent control of innateimmunity inCaenorhabditis elegansby the TIR domain adaptor protein TIR-1, an ortholog of human SARM
    • CouillaultC, et al.TLR-independent control of innateimmunity inCaenorhabditis elegansby the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nature Immunol 2004;5(5):488-494.
    • (2004) Nature Immunol , vol.5 , Issue.5 , pp. 488-494
    • Couillault, C.1
  • 28
    • 38949205955 scopus 로고    scopus 로고
    • SARM: A novel Toll-like receptor adaptor, is functionally conserved fromarthropod to human
    • Belinda LW, et al. SARM: a novel Toll-like receptor adaptor, is functionally conserved fromarthropod to human.Mol Immunol 2008;45(6):1732-1742.
    • (2008) Mol Immunol , vol.45 , Issue.6 , pp. 1732-1742
    • Belinda, L.W.1
  • 29
    • 84873557128 scopus 로고    scopus 로고
    • Litopenaeus vannamei sterile-alpha and armadillo motif containing protein (LvSARM) is involved in regulation of Penaeidins and antilipopolysaccharide factors
    • Wang PH, et al. Litopenaeus vannamei sterile-alpha and armadillo motif containing protein (LvSARM) is involved in regulation of Penaeidins and antilipopolysaccharide factors. PLoS One 2013;8(2):e52088.
    • (2013) PLoS One , vol.8 , Issue.2 , pp. e52088
    • Wang, P.H.1
  • 30
    • 85027940931 scopus 로고    scopus 로고
    • Molecular characterization of porcine SARM1 and its role in regulating TLRs signaling during highly pathogenic porcine reproductive and respiratory syndromevirus infection in vivo
    • Zhou X, et al.Molecular characterization of porcine SARM1 and its role in regulating TLRs signaling during highly pathogenic porcine reproductive and respiratory syndromevirus infection in vivo.Dev Comp Immunol 2013;39(1-2):117-26.
    • (2013) Dev Comp Immunol , vol.39 , Issue.1-2 , pp. 117-126
    • Zhou, X.1
  • 31
    • 79951943072 scopus 로고    scopus 로고
    • TIR domain-containing adaptor SARMis a late addition to the ongoingmicrobe-host dialog
    • ZhangQ, et al. TIR domain-containing adaptor SARMis a late addition to the ongoingmicrobe-host dialog. Dev Comp Immunol 2011;35(4):461-468.
    • (2011) Dev Comp Immunol , vol.35 , Issue.4 , pp. 461-468
    • Zhang, Q.1
  • 32
    • 33748871187 scopus 로고    scopus 로고
    • Thehuman adaptor SARM negatively regulates adaptor protein TRIF-dependent Tolllike receptor signaling
    • CartyM, et al.Thehuman adaptor SARM negatively regulates adaptor protein TRIF-dependent Tolllike receptor signaling. Nat Immunol 2006;7(10):1074-1081.
    • (2006) Nat Immunol , vol.7 , Issue.10 , pp. 1074-1081
    • Carty, M.1
  • 33
    • 77953315434 scopus 로고    scopus 로고
    • SARM inhibits both TRIF- and MyD88-mediated AP-1 activation
    • Peng J, et al. SARM inhibits both TRIF- and MyD88-mediated AP-1 activation. Eur J Immunol 2010;40(6):1738-1747.
    • (2010) Eur J Immunol , vol.40 , Issue.6 , pp. 1738-1747
    • Peng, J.1
  • 34
    • 77953642433 scopus 로고    scopus 로고
    • AmphioxusSARMinvolved in neural developmentmay function as a suppressor of TLR signaling
    • Yuan S, et al. AmphioxusSARMinvolved in neural developmentmay function as a suppressor of TLR signaling. J Immunol 2010;184(12):6874-6881.
    • (2010) J Immunol , vol.184 , Issue.12 , pp. 6874-6881
    • Yuan, S.1
  • 35
    • 2342475724 scopus 로고    scopus 로고
    • Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response
    • Liberati NT, et al. Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. Proc Natl Acad Sci USA 2004;101(17): 6593-6598.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.17 , pp. 6593-6598
    • Liberati, N.T.1
  • 36
    • 34548424488 scopus 로고    scopus 로고
    • MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival
    • Kim Y, et al. MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival. J ExpMed 2007;204(9):2063-2074.
    • (2007) J ExpMed , vol.204 , Issue.9 , pp. 2063-2074
    • Kim, Y.1
  • 37
    • 69449098052 scopus 로고    scopus 로고
    • The immune adaptormolecule SARMmodulates tumor necrosis factor alpha production and microglia activation in the brainstem and restrictsWest Nile Virus pathogenesis
    • Szretter KJ, et al. The immune adaptormolecule SARMmodulates tumor necrosis factor alpha production and microglia activation in the brainstem and restrictsWest Nile Virus pathogenesis. J Virol 2009;83(18):9329-9338.
    • (2009) J Virol , vol.83 , Issue.18 , pp. 9329-9338
    • Szretter, K.J.1
  • 38
    • 84901267655 scopus 로고    scopus 로고
    • SARM Regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter
    • Gurtler C, et al. SARM Regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter. J Immunol 2014;192(10):4821-4832.
    • (2014) J Immunol , vol.192 , Issue.10 , pp. 4821-4832
    • Gurtler, C.1
  • 39
    • 84873723800 scopus 로고    scopus 로고
    • T-cell death following immune activation is mediated by mitochondrialocalized SARM
    • Panneerselvam P, et al. T-cell death following immune activation is mediated by mitochondrialocalized SARM. Cell Death Differ 2013;20(3):478-489.
    • (2013) Cell Death Differ , vol.20 , Issue.3 , pp. 478-489
    • Panneerselvam, P.1
  • 40
    • 84863178511 scopus 로고    scopus 로고
    • Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: Definition of the critical region and residues in the signal sequence
    • Panneerselvam P, et al. Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence. Biochem J 2012a;442(2):263-271.
    • (2012) Biochem J , vol.442 , Issue.2 , pp. 263-271
    • Panneerselvam, P.1
  • 41
    • 0028266975 scopus 로고
    • A repeating amino acid motif shared by proteins with diverse cellular roles
    • Peifer M, Berg S, Reynolds AB. A repeating amino acid motif shared by proteins with diverse cellular roles. Cell 1994;76(5):789-791.
    • (1994) Cell , vol.76 , Issue.5 , pp. 789-791
    • Peifer, M.1    Berg, S.2    Reynolds, A.B.3
  • 42
    • 0142106808 scopus 로고    scopus 로고
    • Armadillo repeat proteins: Beyond the animal kingdom
    • Coates JC. Armadillo repeat proteins: beyond the animal kingdom. Trends Cell Biol 2003;13(9):463-471.
    • (2003) Trends Cell Biol , vol.13 , Issue.9 , pp. 463-471
    • Coates, J.C.1
  • 43
    • 0029091904 scopus 로고
    • SAM: A novel motif in yeast sterile and Drosophila polyhomeotic proteins
    • Ponting CP. SAM: a novel motif in yeast sterile and Drosophila polyhomeotic proteins. Protein Sci 1995;4(9):1928-1930.
    • (1995) Protein Sci , vol.4 , Issue.9 , pp. 1928-1930
    • Ponting, C.P.1
  • 44
    • 0031022602 scopus 로고    scopus 로고
    • SAM as a protein interaction domain involved in developmental regulation
    • Schultz J, et al. SAM as a protein interaction domain involved in developmental regulation. Protein Sci 1997;6(1):249-253.
    • (1997) Protein Sci , vol.6 , Issue.1 , pp. 249-253
    • Schultz, J.1
  • 45
    • 0344196904 scopus 로고    scopus 로고
    • SAM domains: Uniform structure, diversity of function
    • Kim CA, Bowie JU. SAM domains: uniform structure, diversity of function. Trends Biochem Sci 2003;28(12):625-628.
    • (2003) Trends Biochem Sci , vol.28 , Issue.12 , pp. 625-628
    • Kim, C.A.1    Bowie, J.U.2
  • 46
    • 12144283454 scopus 로고    scopus 로고
    • A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling
    • Chuang CF, Bargmann CI. A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Genes Dev 2005;19(2): 270-281.
    • (2005) Genes Dev , vol.19 , Issue.2 , pp. 270-281
    • Chuang, C.F.1    Bargmann, C.I.2
  • 47
    • 84866147760 scopus 로고    scopus 로고
    • The microRNA mir-71 inhibits calcium signaling by targeting the TIR-1/Sarm1 adaptor protein to control stochastic L/R neuronal asymmetry in C
    • Hsieh YW, Chang C, Chuang CF. The microRNA mir-71 inhibits calcium signaling by targeting the TIR-1/Sarm1 adaptor protein to control stochastic L/R neuronal asymmetry in C. elegans. PLoS Genet 2012;8(8):e1002864.
    • (2012) Elegans. PLoS Genet , vol.8 , Issue.8 , pp. e1002864
    • Hsieh, Y.W.1    Chang, C.2    Chuang, C.F.3
  • 48
    • 79958191516 scopus 로고    scopus 로고
    • Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology
    • Chen CY, et al. Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology. J Cell Biol 2011;193(4):769-784.
    • (2011) J Cell Biol , vol.193 , Issue.4 , pp. 769-784
    • Chen, C.Y.1
  • 49
    • 84884494185 scopus 로고    scopus 로고
    • SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria
    • Murata H, et al. SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. Mol Biol Cell 2013;24(18):2772-2784.
    • (2013) Mol Biol Cell , vol.24 , Issue.18 , pp. 2772-2784
    • Murata, H.1
  • 50
    • 84876765376 scopus 로고    scopus 로고
    • Activation of the innate signalingmoleculeMAVS by Bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death
    • Mukherjee P, et al. Activation of the innate signalingmoleculeMAVS by Bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death. Immunity 2013;38(4):705-716.
    • (2013) Immunity , vol.38 , Issue.4 , pp. 705-716
    • Mukherjee, P.1
  • 51
    • 0032054648 scopus 로고    scopus 로고
    • Severe energy impairment consequent to inactivation ofmitochondrial ATP synthase as an early event in cell death: A mechanism for the selective sensitivity to H2O2 of differentiating erythroleukemia cells
    • Comelli M, LonderoD,Mavelli I. Severe energy impairment consequent to inactivation ofmitochondrial ATP synthase as an early event in cell death: a mechanism for the selective sensitivity to H2O2 of differentiating erythroleukemia cells. Free Radic BiolMed 1998;24(6):924-932.
    • (1998) Free Radic BiolMed , vol.24 , Issue.6 , pp. 924-932
    • Comelli, M.1    Londero, D.2    Mavelli, I.3
  • 52
    • 3042853063 scopus 로고    scopus 로고
    • C-reactive protein: A predominant LPS-binding acute phase protein responsive to Pseudomonas infection
    • Ng PM, et al.C-reactive protein: a predominant LPS-binding acute phase protein responsive to Pseudomonas infection. J Endotoxin Res 2004;10(3):163-174.
    • (2004) J Endotoxin Res , vol.10 , Issue.3 , pp. 163-174
    • Ng, P.M.1
  • 53
    • 27844477305 scopus 로고    scopus 로고
    • Spatial and temporal coordination of expression of immune response genes during Pseudomonas infection of horseshoe crab, Carcinoscorpius rotundicauda
    • Ding JL, et al. Spatial and temporal coordination of expression of immune response genes during Pseudomonas infection of horseshoe crab, Carcinoscorpius rotundicauda. Genes Immun 2005;6(7):557-574.
    • (2005) Genes Immun , vol.6 , Issue.7 , pp. 557-574
    • Ding, J.L.1
  • 54
    • 79959424118 scopus 로고    scopus 로고
    • Burkholderia pseudomallei-induced expression of a negative regulator, sterile-alpha and Armadillo motif-containing protein, in mouse macrophages: A possible mechanism for suppression of the MyD88-independent pathway
    • Pudla M, Limposuwan K, Utaisincharoen P. Burkholderia pseudomallei-induced expression of a negative regulator, sterile-alpha and Armadillo motif-containing protein, in mouse macrophages: a possible mechanism for suppression of the MyD88-independent pathway. Infect Immun 2011;79(7):2921-2927.
    • (2011) Infect Immun , vol.79 , Issue.7 , pp. 2921-2927
    • Pudla, M.1    Limposuwan, K.2    Utaisincharoen, P.3
  • 55
    • 84896959806 scopus 로고    scopus 로고
    • Resveratrol inhibits the TRIF-dependent pathway by upregulating sterile alpha and armadillo motif protein, contributing to anti-inflammatory effects after respiratory syncytial virus infection
    • Liu T, et al. Resveratrol inhibits the TRIF-dependent pathway by upregulating sterile alpha and armadillo motif protein, contributing to anti-inflammatory effects after respiratory syncytial virus infection. J Virol 2014;88(8):4229-4236.
    • (2014) J Virol , vol.88 , Issue.8 , pp. 4229-4236
    • Liu, T.1
  • 56
    • 79551696483 scopus 로고    scopus 로고
    • Activated oncogenic pathways and therapeutic targets in extranodal nasal-type NK/T cell lymphoma revealed by gene expression profiling
    • Ng SB, et al. Activated oncogenic pathways and therapeutic targets in extranodal nasal-type NK/T cell lymphoma revealed by gene expression profiling. J Pathol 2011;223(4):496-510.
    • (2011) J Pathol , vol.223 , Issue.4 , pp. 496-510
    • Ng, S.B.1
  • 57
    • 84892694863 scopus 로고    scopus 로고
    • Neuronally-expressed Sarm1 regulates expression of inflammatory and antiviral cytokines in brains
    • Lin CW, et al. Neuronally-expressed Sarm1 regulates expression of inflammatory and antiviral cytokines in brains. Innate Immun 2014;20(2):161-172.
    • (2014) Innate Immun , vol.20 , Issue.2 , pp. 161-172
    • Lin, C.W.1
  • 58
    • 84880117379 scopus 로고    scopus 로고
    • SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection
    • Hou YJ, et al. SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection. J Immunol 2013;191(2):875-883.
    • (2013) J Immunol , vol.191 , Issue.2 , pp. 875-883
    • Hou, Y.J.1
  • 59
    • 79953191495 scopus 로고    scopus 로고
    • Regulation of anoxic death in Caenorhabditis elegans by mammalian apoptosis signal-regulating kinase (ASK) family proteins
    • Hayakawa T, et al. Regulation of anoxic death in Caenorhabditis elegans by mammalian apoptosis signal-regulating kinase (ASK) family proteins. Genetics 2011;187(3):785-792.
    • (2011) Genetics , vol.187 , Issue.3 , pp. 785-792
    • Hayakawa, T.1
  • 60
    • 72649094825 scopus 로고    scopus 로고
    • Tissue-specific activities of an immune signaling module regulate physiological responses to pathogenic and nutritional bacteria in C
    • Shivers RP, et al. Tissue-specific activities of an immune signaling module regulate physiological responses to pathogenic and nutritional bacteria in C. elegans. CellHostMicrobe 2009;6(4):321-330.
    • (2009) Elegans. CellHostMicrobe , vol.6 , Issue.4 , pp. 321-330
    • Shivers, R.P.1
  • 61
    • 84864332905 scopus 로고    scopus 로고
    • DSarm/Sarm1 is required for activation of an injury-induced axon death pathway
    • Osterloh JM, et al. dSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science 2012;337(6093):481-484.
    • (2012) Science , vol.337 , Issue.6093 , pp. 481-484
    • Osterloh, J.M.1
  • 62
    • 84876491616 scopus 로고    scopus 로고
    • Excitotoxicity upregulates SARM1 protein expression and promotes Wallerian-like degeneration of retinal ganglion cells and their axons
    • Massoll C, Mando W, Chintala SK. Excitotoxicity upregulates SARM1 protein expression and promotes Wallerian-like degeneration of retinal ganglion cells and their axons. Invest Ophthalmol Vis Sci 2013;54(4):2771-2780.
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , Issue.4 , pp. 2771-2780
    • Massoll, C.1    Mando, W.2    Chintala, S.K.3
  • 63
    • 84905916117 scopus 로고    scopus 로고
    • Ubiquitination by SAG regulates macrophage survival/death and immune response during infection
    • Chang SC, Ding JL. Ubiquitination by SAG regulates macrophage survival/death and immune response during infection. Cell Death Differ 2014;21(9):1388-1398.
    • (2014) Cell Death Differ , vol.21 , Issue.9 , pp. 1388-1398
    • Chang, S.C.1    Ding, J.L.2
  • 64
    • 84903954827 scopus 로고    scopus 로고
    • Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons
    • Summers DW, DiAntonio A,Milbrandt J.Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons. J Neurosci 2014;34(28):9338-9350.
    • (2014) J Neurosci , vol.34 , Issue.28 , pp. 9338-9350
    • Summers, D.W.1    DiAntonio, A.2    Milbrandt, J.3
  • 65
    • 84884901353 scopus 로고    scopus 로고
    • UXT plays dual opposing roles on SARM-induced apoptosis
    • Sethurathinam S, et al. UXT plays dual opposing roles on SARM-induced apoptosis. FEBS Lett 2013;587(20):3296-302.
    • (2013) FEBS Lett , vol.587 , Issue.20 , pp. 3296-3302
    • Sethurathinam, S.1
  • 66
    • 0029730738 scopus 로고    scopus 로고
    • A conserved signaling pathway: The Drosophila toll-dorsal pathway
    • Belvin,MP, Anderson KV. A conserved signaling pathway: the Drosophila toll-dorsal pathway. Ann Rev Cell Dev Biol 1996;12:393-416.
    • (1996) Ann Rev Cell Dev Biol , vol.12 , pp. 393-416
    • Belvin, M.P.1    Anderson, K.V.2
  • 67
    • 84896703127 scopus 로고    scopus 로고
    • Sarm1, aneuronalinflammatory regulator, controls social interaction, associative memory and cognitive flexibility in mice
    • LinCW,Hsueh YP. Sarm1, aneuronalinflammatory regulator, controls social interaction, associative memory and cognitive flexibility in mice. Brain Behav immun 2014;37:142-151.
    • (2014) Brain Behav Immun , vol.37 , pp. 142-151
    • Lin, C.W.1    Hsueh, Y.P.2
  • 68
    • 36348932053 scopus 로고    scopus 로고
    • Retinoschisin (RS1), the protein encoded by theX-linked retinoschisis gene, is anchored to the surface of retinal photoreceptor and bipolar cells through its interactions with a Na/K ATPase-SARM1 complex
    • Molday LL,WuWW,MoldayRS.Retinoschisin (RS1), the protein encoded by theX-linked retinoschisis gene, is anchored to the surface of retinal photoreceptor and bipolar cells through its interactions with a Na/K ATPase-SARM1 complex. J Biol Chem 2007;282(45):32792-32801.
    • (2007) J Biol Chem , vol.282 , Issue.45 , pp. 32792-32801
    • Molday, L.L.1    Wu, W.W.2    Molday, R.S.3
  • 69
    • 2342425038 scopus 로고    scopus 로고
    • Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport
    • Tatebayashi Y, et al. Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport. J Cell Sci 2004;117(Pt 9):1653-1663.
    • (2004) J Cell Sci , vol.117 , pp. 1653-1663
    • Tatebayashi, Y.1
  • 70
    • 7244242456 scopus 로고    scopus 로고
    • Beta-actin is required for mitochondria clustering and ROS generation in TNF-induced, caspase-independent cell death
    • Li J, et al. Beta-actin is required for mitochondria clustering and ROS generation in TNF-induced, caspase-independent cell death. J Cell Sci 2004;117(Pt 20):4673-4680.
    • (2004) J Cell Sci , vol.117 , pp. 4673-4680
    • Li, J.1
  • 71
    • 34447634288 scopus 로고    scopus 로고
    • UXT (Ubiquitously Expressed Transcript) causes mitochondrial aggregation
    • Moss TN, et al. UXT (Ubiquitously Expressed Transcript) causes mitochondrial aggregation. In vitro cellular & developmental biology. Animal 2007;43(3-4):139-146.
    • (2007) Vitro Cellular & Developmental Biology. Animal , vol.43 , Issue.3-4 , pp. 139-146
    • Moss, T.N.1
  • 72
    • 12144283454 scopus 로고    scopus 로고
    • A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1MAPKKK signaling
    • Chuang CF, Bargmann CI. A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1MAPKKK signaling. Genes Dev 2005;19(2):270-281.
    • (2005) Genes Dev , vol.19 , Issue.2 , pp. 270-281
    • Chuang, C.F.1    Bargmann, C.I.2
  • 73
    • 77953315434 scopus 로고    scopus 로고
    • SARM inhibits both TRIF- and MyD88-mediated AP-1 activation
    • Peng J, et al. SARM inhibits both TRIF- and MyD88-mediated AP-1 activation. Eur J Immunol 2010;40(6):1738-1747.
    • (2010) Eur J Immunol , vol.40 , Issue.6 , pp. 1738-1747
    • Peng, J.1
  • 74
    • 50349093261 scopus 로고    scopus 로고
    • Themitochondrial antiviral signaling protein,MAVS, is cleaved during apoptosis
    • Scott I, Norris KL.Themitochondrial antiviral signaling protein,MAVS, is cleaved during apoptosis. Bioch Biophys Res Commun 2008;375(1):101-106.
    • (2008) Bioch Biophys Res Commun , vol.375 , Issue.1 , pp. 101-106
    • Scott, I.1    Norris, K.L.2
  • 75
    • 33847672241 scopus 로고    scopus 로고
    • NF-kappaB activation by the Toll-IL-1 receptordomain proteinMyD88 adapter-like is regulated by caspase-1
    • Miggin SM, et al.NF-kappaB activation by the Toll-IL-1 receptordomain proteinMyD88 adapter-like is regulated by caspase-1. Proc Natl Acad Sci USA 2007;104(9):3372-3377.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.9 , pp. 3372-3377
    • Miggin, S.M.1


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