메뉴 건너뛰기




Volumn 223, Issue 4, 2011, Pages 496-510

Activated oncogenic pathways and therapeutic targets in extranodal nasal-type NK/T cell lymphoma revealed by gene expression profiling

Author keywords

gene expression profiling; Myc; NF B; NK T cell lymphoma; p53; paraffin embedded tissue; survivin

Indexed keywords

AURORA A KINASE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; POLO LIKE KINASE 1; PROTEIN P53; SURVIVIN; TERAMEPROCOL;

EID: 79551696483     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2823     Document Type: Article
Times cited : (131)

References (49)
  • 2
    • 0030160493 scopus 로고    scopus 로고
    • Epstein-Barr virus in T and natural killer (NK) cell non-Hodgkin's lymphomas
    • Kanavaros P, Briere J, Emile JF, et al., Epstein-Barr virus in T and natural killer (NK) cell non-Hodgkin's lymphomas. Leukemia 1996; 10 (Suppl 2): s84-s87. (Pubitemid 126754016)
    • (1996) Leukemia , vol.10 , Issue.SUPPL. 2
    • Kanavaros, P.1    Briere, J.2    Emile, J.-F.3    Gaulard, P.4
  • 3
    • 0035815216 scopus 로고    scopus 로고
    • The latency pattern of Epstein-Barr virus infection and viral IL-10 expression in cutaneous natural killer/T-cell lymphomas
    • DOI 10.1054/bjoc.2000.1687
    • Xu ZG, Iwatsuki K, Oyama N, et al., The latency pattern of Epstein-Barr virus infection and viral IL-10 expression in cutaneous natural killer/T-cell lymphomas. Br J Cancer 2001; 84: 920-925. (Pubitemid 32385835)
    • (2001) British Journal of Cancer , vol.84 , Issue.7 , pp. 920-925
    • Xu, Z.-G.1    Iwatsuki, K.2    Oyama, N.3    Ohtsuka, M.4    Satoh, M.5    Kikuchi, S.6    Akiba, H.7    Kaneko, F.8
  • 5
    • 1642539989 scopus 로고    scopus 로고
    • P53, N- and K-Ras, and β-Catenin Gene Mutations and Prognostic Factors in Nasal NK/T-Cell Lymphoma from Hokkaido, Japan
    • DOI 10.1016/j.humpath.2003.08.025
    • Takahara M, Kishibe K, Bandoh N, et al., P53, N- and K-Ras, and beta-catenin gene mutations and prognostic factors in nasal NK/T-cell lymphoma from Hokkaido, Japan. Hum Pathol 2004; 35: 86-95. (Pubitemid 38133927)
    • (2004) Human Pathology , vol.35 , Issue.1 , pp. 86-95
    • Takahara, M.1    Kishibe, K.2    Bandoh, N.3    Nonaka, S.4    Harabuchi, Y.5
  • 7
    • 0028791591 scopus 로고
    • Frequent expression of P-glycoprotein/MDR1 by nasal T-cell lymphoma cells
    • Yamaguchi M, Kita K, Miwa H, et al., Frequent expression of P-glycoprotein/MDR1 by nasal T-cell lymphoma cells. Cancer 1995; 76: 2351-2356.
    • (1995) Cancer , vol.76 , pp. 2351-2356
    • Yamaguchi, M.1    Kita, K.2    Miwa, H.3
  • 8
    • 33847357051 scopus 로고    scopus 로고
    • Expression of the granzyme B inhibitor PI9 predicts outcome in nasal NK/T-cell lymphoma: Results of a Western series of 48 patients treated with first-line polychemotherapy within the Groupe d'Etude des Lymphomes de l'Adulte (GELA) trials
    • DOI 10.1182/blood-2006-07-033142
    • Bossard C, Belhadj K, Reyes F, et al., Expression of the granzyme B inhibitor PI9 predicts outcome in nasal NK/T-cell lymphoma: results of a Western series of 48 patients treated with first-line polychemotherapy within the Groupe d'Etude des Lymphomes de l'Adulte (GELA) trials. Blood 2007; 109: 2183-2189. (Pubitemid 46348221)
    • (2007) Blood , vol.109 , Issue.5 , pp. 2183-2189
    • Bossard, C.1    Belhadj, K.2    Reyes, F.3    Martin-Garcia, N.4    Berger, F.5    Kummer, J.A.6    Briere, J.7    Baglin, A.-C.8    Cheze, S.9    Bosq, J.10    Ribrag, V.11    Gisselbrecht, C.12    Mounier, N.13    Gaulard, P.14
  • 9
    • 0036842241 scopus 로고    scopus 로고
    • Genetic changes in natural killer cell neoplasms
    • DOI 10.1016/S0145-2126(02)00065-6, PII S0145212602000656
    • Wong KF,. Genetic changes in natural killer cell neoplasms. Leuk Res 2002; 26: 977-978. (Pubitemid 35287205)
    • (2002) Leukemia Research , vol.26 , Issue.11 , pp. 977-978
    • Wong, K.F.1
  • 10
    • 67349138549 scopus 로고    scopus 로고
    • Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies
    • Iqbal J, Kucuk C, Deleeuw RJ, et al., Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies. Leukemia 2009; 23: 1139-1151.
    • (2009) Leukemia , vol.23 , pp. 1139-1151
    • Iqbal, J.1    Kucuk, C.2    Deleeuw, R.J.3
  • 11
    • 77949535492 scopus 로고    scopus 로고
    • Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type
    • Huang Y, de Reynies A, de Leval L, et al., Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type. Blood 2010; 115: 1226-1237.
    • (2010) Blood , vol.115 , pp. 1226-1237
    • Huang, Y.1    De Reynies, A.2    De Leval, L.3
  • 12
    • 57349090407 scopus 로고    scopus 로고
    • Gene expression in fixed tissues and outcome in hepatocellular carcinoma
    • Hoshida Y, Villanueva A, Kobayashi M, et al., Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med 2008; 359: 1995-2004.
    • (2008) N Engl J Med , vol.359 , pp. 1995-2004
    • Hoshida, Y.1    Villanueva, A.2    Kobayashi, M.3
  • 13
    • 67650002013 scopus 로고    scopus 로고
    • NF-kappaB activation through the alternative pathway correlates with chemoresistance and poor survival in extranodal NK/T-cell lymphoma, nasal type
    • Liu X, Wang B, Ma X, et al., NF-kappaB activation through the alternative pathway correlates with chemoresistance and poor survival in extranodal NK/T-cell lymphoma, nasal type. Jpn J Clin Oncol 2009; 39: 418-424.
    • (2009) Jpn J Clin Oncol , vol.39 , pp. 418-424
    • Liu, X.1    Wang, B.2    Ma, X.3
  • 14
    • 0034093625 scopus 로고    scopus 로고
    • Malignant hematopoietic cell lines: In Vitro models for the study of natural killer cell leukemia-lymphoma
    • Drexler HG, Matsuo Y,. Malignant hematopoietic cell lines: in vitro models for the study of natural killer cell leukemia-lymphoma. Leukemia 2000; 14: 777-782. (Pubitemid 30235051)
    • (2000) Leukemia , vol.14 , Issue.5 , pp. 777-782
    • Drexler, H.G.1    Matsuo, Y.2
  • 15
    • 0038353371 scopus 로고    scopus 로고
    • Immunoprofiling of cell lines derived from natural killer-cell and natural killer-like T-cell leukemia-lymphoma
    • DOI 10.1016/S0145-2126(03)00024-9
    • Matsuo Y, Drexler HG,. Immunoprofiling of cell lines derived from natural killer-cell and natural killer-like T-cell leukemia-lymphoma. Leuk Res 2003; 27: 935-945. (Pubitemid 36809090)
    • (2003) Leukemia Research , vol.27 , Issue.10 , pp. 935-945
    • Matsuo, Y.1    Drexler, H.G.2
  • 19
    • 34447628843 scopus 로고    scopus 로고
    • Pathway mapping tools for analysis of high content data
    • Ekins S, Nikolsky Y, Bugrim A, et al., Pathway mapping tools for analysis of high content data. Methods Mol Biol 2007; 356: 319-350.
    • (2007) Methods Mol Biol , vol.356 , pp. 319-350
    • Ekins, S.1    Nikolsky, Y.2    Bugrim, A.3
  • 20
    • 33751419806 scopus 로고    scopus 로고
    • The incidence and anatomic site specificity of chromosomal translocations in primary extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in North America
    • DOI 10.1097/01.pas.0000213275.60962.2a, PII 0000047820061200000007
    • Remstein ED, Dogan A, Einerson RR, et al., The incidence and anatomic site specificity of chromosomal translocations in primary extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in North America. Am J Surg Pathol 2006; 30: 1546-1553. (Pubitemid 44815508)
    • (2006) American Journal of Surgical Pathology , vol.30 , Issue.12 , pp. 1546-1553
    • Remstein, E.D.1    Dogan, A.2    Einerson, R.R.3    Paternoster, S.F.4    Fink, S.R.5    Law, M.6    Dewald, G.W.7    Kurtin, P.J.8
  • 21
    • 0032080335 scopus 로고    scopus 로고
    • Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting
    • DOI 10.1074/jbc.273.18.11177
    • Ambrosini G, Adida C, Sirugo G, et al., Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting. J Biol Chem 1998; 273: 11177-11182. (Pubitemid 28204967)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.18 , pp. 11177-11182
    • Ambrosini, G.1    Adida, C.2    Sirugo, G.3    Altieri, D.C.4
  • 24
    • 33645316142 scopus 로고    scopus 로고
    • Targeting polo-like kinase 1 for cancer therapy
    • Strebhardt K, Ullrich A,. Targeting polo-like kinase 1 for cancer therapy. Nature Rev Cancer 2006; 6: 321-330.
    • (2006) Nature Rev Cancer , vol.6 , pp. 321-330
    • Strebhardt, K.1    Ullrich, A.2
  • 25
    • 60749109846 scopus 로고    scopus 로고
    • Cell cycle, CDKs and cancer: A changing paradigm
    • Malumbres M, Barbacid M, Cell cycle, CDKs and cancer: a changing paradigm. Nature Rev Cancer 2009; 9: 153-166.
    • (2009) Nature Rev Cancer , vol.9 , pp. 153-166
    • Malumbres, M.1    Barbacid, M.2
  • 27
    • 79551712038 scopus 로고    scopus 로고
    • Predicting the oncogenic pathway activities of individual samples from microarray gene expression profiles
    • Hangzhou, China
    • Huang G, Chng WJ,. Predicting the oncogenic pathway activities of individual samples from microarray gene expression profiles. In 2009 International Workshop on Computational and Integrative Biology (CIB 2009), Hangzhou, China, 2009; 20-25.
    • (2009) 2009 International Workshop on Computational and Integrative Biology (CIB 2009) , pp. 20-25
    • Huang, G.1    Chng, W.J.2
  • 28
    • 28544444488 scopus 로고    scopus 로고
    • Natural killer-cell malignancies: Diagnosis and treatment
    • Kwong YL,. Natural killer-cell malignancies: diagnosis and treatment. Leukemia 2005; 19: 2186-2194.
    • (2005) Leukemia , vol.19 , pp. 2186-2194
    • Kwong, Y.L.1
  • 29
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li Q, Verma IM,. NF-kappaB regulation in the immune system. Nature Rev Immunol 2002; 2: 725-734.
    • (2002) Nature Rev Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 30
    • 33947605546 scopus 로고    scopus 로고
    • NF-kappa B signaling and carcinogenesis
    • Okamoto T, Sanda T, Asamitsu K,. NF-kappa B signaling and carcinogenesis. Curr Pharm Des 2007; 13: 447-462.
    • (2007) Curr Pharm des , vol.13 , pp. 447-462
    • Okamoto, T.1    Sanda, T.2    Asamitsu, K.3
  • 31
    • 0034518556 scopus 로고    scopus 로고
    • Constitutive expression of NF-κB is a characteristic feature of mycosis fungoides: Implications for apoptosis resistance and pathogenesis
    • DOI 10.1053/hupa.2000.20370
    • Izban KF, Ergin M, Qin JZ, et al., Constitutive expression of NF-kappa B is a characteristic feature of mycosis fungoides: implications for apoptosis resistance and pathogenesis. Hum Pathol 2000; 31: 1482-1490. (Pubitemid 32047000)
    • (2000) Human Pathology , vol.31 , Issue.12 , pp. 1482-1490
    • Izban, K.F.1    Ergin, M.2    Qin, J.-Z.3    Martinez, R.L.4    Pooley Jr., R.J.5    Saeed, S.6    Alkan, S.7
  • 33
    • 27744548150 scopus 로고    scopus 로고
    • Effects of nuclear factor-κB inhibitors and its implication on natural killer T-cell lymphoma cells
    • DOI 10.1111/j.1365-2141.2005.05720.x
    • Kim K, Ryu K, Ko Y, et al., Effects of nuclear factor-kappaB inhibitors and its implication on natural killer T-cell lymphoma cells. Br J Haematol 2005; 131: 59-66. (Pubitemid 43899708)
    • (2005) British Journal of Haematology , vol.131 , Issue.1 , pp. 59-66
    • Kim, K.1    Ryu, K.2    Ko, Y.3    Park, C.4
  • 35
    • 34347400984 scopus 로고    scopus 로고
    • Proteasome inhibitor bortezomib-induced apoptosis in natural killer (NK) - Cell leukemia and lymphoma: An in vitro and in vivo preclinical evaluation [2]
    • DOI 10.1182/blood-2007-02-072900
    • Shen L, Au WY, Guo T, et al., Proteasome inhibitor bortezomib-induced apoptosis in natural killer (NK)-cell leukemia and lymphoma: an in vitro and in vivo preclinical evaluation. Blood 2007; 110: 469-470. (Pubitemid 47026871)
    • (2007) Blood , vol.110 , Issue.1 , pp. 469-470
    • Shen, L.1    Au, W.-Y.2    Guo, T.3    Wong, K.-Y.4    Wong, M.L.5    Tsuchiyama, J.6    Yuen, P.-W.7    Kwong, Y.-L.8    Liang, R.H.9    Srivastava, G.10
  • 37
    • 66649127621 scopus 로고    scopus 로고
    • Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma
    • Compagno M, Lim WK, Grunn A, et al., Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma. Nature 2009; 459: 717-721.
    • (2009) Nature , vol.459 , pp. 717-721
    • Compagno, M.1    Lim, W.K.2    Grunn, A.3
  • 38
  • 40
  • 41
    • 65349124094 scopus 로고    scopus 로고
    • C-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells
    • Faumont N, Durand-Panteix S, Schlee M, et al., c-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells. J Virol 2009; 83: 5014-5027.
    • (2009) J Virol , vol.83 , pp. 5014-5027
    • Faumont, N.1    Durand-Panteix, S.2    Schlee, M.3
  • 42
    • 35948959024 scopus 로고    scopus 로고
    • The universal character of the tumor-associated antigen survivin
    • DOI 10.1158/1078-0432.CCR-07-0686
    • Andersen MH, Svane IM, Becker JC, et al., The universal character of the tumor-associated antigen survivin. Clin Cancer Res 2007; 13: 5991-5994. (Pubitemid 350075053)
    • (2007) Clinical Cancer Research , vol.13 , Issue.20 , pp. 5991-5994
    • Andersen, M.H.1    Svane, I.2    Becker, J.C.3    Straten, P.T.4
  • 43
    • 38949212974 scopus 로고    scopus 로고
    • Thrombospondin-1 (TSP-1) and Survivin (S) expression in non-Hogkin's lymphomas
    • DOI 10.1016/j.leukres.2007.06.024, PII S0145212607002603
    • Paydas S, Ergin M, Erdogan S, et al., Thrombospondin-1 (TSP-1) and survivin (S) expression in non-Hogkin's lymphomas. Leuk Res 2008; 32: 243-250. (Pubitemid 351215546)
    • (2008) Leukemia Research , vol.32 , Issue.2 , pp. 243-250
    • Paydas, S.1    Ergin, M.2    Erdogan, S.3    Seydaoglu, G.4    Yavuz, S.5    Disel, U.6
  • 44
    • 38849209818 scopus 로고    scopus 로고
    • Survivin repression by p53, Rb and E2F2 in normal human melanocytes
    • DOI 10.1093/carcin/bgm219
    • Raj D, Liu T, Samadashwily G, et al., Survivin repression by p53, Rb and E2F2 in normal human melanocytes. Carcinogenesis 2008; 29: 194-201. (Pubitemid 351201759)
    • (2008) Carcinogenesis , vol.29 , Issue.1 , pp. 194-201
    • Raj, D.1    Liu, T.2    Samadashwily, G.3    Li, F.4    Grossman, D.5
  • 45
    • 65449117656 scopus 로고    scopus 로고
    • Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML
    • Zhou J, Bi C, Janakakumara JV, et al., Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML. Blood 2009; 113: 4052-4062.
    • (2009) Blood , vol.113 , pp. 4052-4062
    • Zhou, J.1    Bi, C.2    Janakakumara, J.V.3
  • 46
    • 43549087444 scopus 로고    scopus 로고
    • PRDM1 is involved in chemoresistance of T-cell lymphoma and down-regulated by the proteasome inhibitor
    • Zhao WL, Liu YY, Zhang QL, et al., PRDM1 is involved in chemoresistance of T-cell lymphoma and down-regulated by the proteasome inhibitor. Blood 2008; 111: 3867-3871.
    • (2008) Blood , vol.111 , pp. 3867-3871
    • Zhao, W.L.1    Liu, Y.Y.2    Zhang, Q.L.3
  • 47
    • 17044386646 scopus 로고    scopus 로고
    • Regulatory events in early and late B-cell differentiation
    • Johnson K, Shapiro-Shelef M, Tunyaplin C, et al., Regulatory events in early and late B-cell differentiation. Mol Immunol 2005; 42: 749-761.
    • (2005) Mol Immunol , vol.42 , pp. 749-761
    • Johnson, K.1    Shapiro-Shelef, M.2    Tunyaplin, C.3
  • 48
    • 0030950523 scopus 로고    scopus 로고
    • Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation
    • DOI 10.1126/science.276.5312.596
    • Lin Y, Wong K, Calame K,. Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. Science 1997; 276: 596-599. (Pubitemid 27193684)
    • (1997) Science , vol.276 , Issue.5312 , pp. 596-599
    • Lin, Y.1    Wong, K.-K.2    Calame, K.3
  • 49
    • 70350234507 scopus 로고    scopus 로고
    • Survivin: A new target for anti-cancer therapy
    • Ryan BM, O'Donovan N, Duffy MJ,. Survivin: a new target for anti-cancer therapy. Cancer Treat Rev 2009; 35: 553-562.
    • (2009) Cancer Treat Rev , vol.35 , pp. 553-562
    • Ryan, B.M.1    O'Donovan, N.2    Duffy, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.