SAM as a protein interaction domain involved in developmental regulation

Protein Science

Volumn 6, Issue 1, 1997, Pages 249-253

  Schultz, Jörg ^a   Ponting, Christopher P ^b   Hofmann, Kay ^c   Bork, Peer ^a,d  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

alignment; EPH receptor protein tyrosine kinases; homology search; protein binding; SAM

Indexed keywords

PROTEIN TYROSINE KINASE;

AMINO ACID SEQUENCE; ARTICLE; DROSOPHILA; EUKARYOTE; GENETIC REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

EID: 0031022602     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560060128     Document Type: Article

References (36)

1. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. 1990. Basic local alignment search tool. J Mol Biol 215:403-410.
2. Bardwell L, Cook JG, Inouye CJ, Thorner J. 1994. Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae. Dev Biol 166:363-379.
3. Barr MM, Tu H, van Aelst L, Wigler M. 1996. Identification of Ste4 as a potential regulator of Byr2 in the sexual response pathway of Schizosaccharomyces pombe. Mol Cell Biol 16:5597-5603.
4. Bender L, Lo HS, Lee H, Kokojan V, Petersen J, Bender A. 1996. Associations among PH and SH3 domain-containing proteins and Rho-type GTPases in yeast. J Cell Biol 133:879-894.
5. Birney E, Thompson JD, Gibson TJ. 1996. PairWise and SearchWise: Finding the optimal alignment in a simultaneous comparison of a protein profile against all DNA translation frames. Nucleic Acids Res 24:2730-2739.
6. Bork P, Gibson T. 1996. Applying motif and profile searches. Meth Enzymol 266:162-184.
7. Bornemann D, Miller E, Simon J. 1996. The Drosophila Polycomb group gene Sex comb on midleg (Scm) encodes a zinc finger protein with similarity to polyhomeotic protein. Development 122:1621-1630.
8. DeCamillis M, Cheng NS, Pierre D, Brock HW. 1992. The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb. Genes Dev 6:223-232.
9. van der Geer P, Hunter T, Lindberg RA. 1994. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu Rev Cell Biol 10:251-337.
10. Gribskov M, McLachlan AD, Eisenberg D. 1987. Profile analysis: Detection of distantly related proteins. Proc Natl Acad Sci USA 84:4355-4358.
11. Hirai H, Maru Y, Hagiwara K, Nishida J, Takaku F. 1987. A novel putative tyrosine kinase receptor encoded by the eph gene. Science 238:1717-1720.
12. Holland SJ, Gale NW, Mbamalu G, Yancopoulos GD, Henkemeyer M, Pawson T. 1996. Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands. Nature 383:122-125.
13. Hynes RO, Lander AD. 1992. Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons. Cell 68:303-322.
14. Iwase T, Tanaka M, Suzuki M, Naito Y, Sugimura H, Kino I. 1993. Identification of protein-tyrosine kinase genes preferentially expressed in embryo stomach and gastric cancer. Biochem Biophys Res Commun 194:698-705.
15. Jackman JK, Motto DG, Sun Q, Tanemoto M, Turck CW, Peltz GA, Koretzky GA, Findell PR. 1995. Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells. J Biol Chem 270:7029-7032.
16. Karin M. 1992. Signal transduction from cell surface to nucleus in development and disease. FASEB J 6:2581-2590.
17. Kiyokawa E, Takai S, Tanaka M, Iwase T, Suzuki M, Xiang YY, Naito Y, Yamada K, Sugimura H, Kino I. 1994. Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors. Cancer Res 54:3645-3650.
18. Mahone M, Saffman EE, Lasko PF. 1995. Localized Bicaudal-C RNA encodes a protein containing a KH domain, the RNA binding motif of FMR1. EMBO J 14:2043-2055.
19. Marcus S, Polverino A, Barr M, Wigler M. 1994. Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module. Proc Natl Acad Sci USA 97:7762-7766.
20. Matsui Y, Matsui R, Akada R, Toh-e A. 1996. Yeast src homology region 3 domain-binding proteins involved in bud formation. J Cell Biol 133:865-878.
21. Neiman AM, Stevenson BJ, Xu HP, Sprague GFJ, Herskowitz I, Wigler M, Marcus S. 1993. Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms. Mol Biol Cell 4:107-120.
22. Nomura M, Takihara Y, Shimada K. 1994. Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: One of the early inducible clones encodes a novel protein sharing several highly homologous regions with a Drosophila Polyhomeotic protein. Differentiation 57:39-50.
23. Pandey A, Duan H, Dixit VM. 1995. Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase. J Biol Chem 270:19201-19204.
24. Ponting CP. 1995. SAM: A novel motif in yeast sterile and Drosophila polyhomeotic proteins. Protein Sci 4:1928-1930.
25. Ponting CP, Benjamin DR. 1996. A novel family of ras binding domains. Trends Biochem Sci (in press).
26. Ponting CP, Phillips C. 1995. DHR domains in syntrophins, neuronal NO synthases and other intracellular proteins. Trends Biochem Sci 20:102-103.
27. Rost B, Sander C, Schneider R. 1994. PHD - An automatic mail server for protein secondary structure prediction. Comput Appl Biosci 10:53-60.
28. Sakane F, Imai S, Wada I, Kanoh H. 1996. Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases. J Biol Chem 271:8394-8401.
29. Schupbach T, Wieschaus E. 1991. Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology. Genetics 129:1119-1136.
30. Serra-Pages C, Kedersha NL, Fazikas L, Medley Q, Debant A, Streuli M. 1995. The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions. EMBO J 14:2827-2838.
31. Stein E, Cerretti DP, Daniel TO. 1996. Ligand activation of ELK receptor tyrosine kinase promotes its association with GrblO and Grb2 in vascular endothelial cells. J Biol Chem 277:23588-23593.
32. Tan JL, Spudich JA. 1990. Developmentally regulated protein-tyrosine kinase genes in Dictyostelium discoideum. Mol Cell Biol 10:3578-3583.
33. Thompson JD, Higgins DG, Gibson TJ. 1994. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673-4680.
34. Tuzi NL, Gullick WJ. 1994. eph, the largest known family of putative growth factor receptors. Br J Cancer 69:417-421.
35. Valenzuela DM, Rojas E, Griffiths JA, Compton DL, Gisser M, Ip NY, Goldfarb M, Yancopoulos GD. 1995. Identification of full-length and truncated forms of Ehk-3, a novel member of the Eph receptor tyrosine kinase family. Oncogene 10:1573-1580.
36. Xu Q, Alldus G, Macdonald R, Wilkinson DG, Holder N. 1996. Function of the Eph-related kinase rtkl in patterning of the zebrafish forebrain. Nature 381:391-322.