Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: Definition of the critical region and residues in the signal sequence

Biochemical Journal

Volumn 442, Issue 2, 2012, Pages 263-271

  Panneerselvam, Porkodi ^a,b   Singh, Laishram Pradeepkumar ^a   Ho, Bow ^c   Chen, Jianzhu ^b   Ding, Jeak Ling ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Arginine; Hydrophobic polybasic domain; Mitochondria targeting signal sequence; Sterile and HEAT armadillo motif containing protein (SARM); Toll like receptor adaptor (TLR adaptor)

Indexed keywords

AMINO ACID DERIVATIVE; ARGININE; ENHANCED GREEN FLUORESCENT PROTEIN; SELECTIVE ANDROGEN RECEPTOR MODULATOR;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; BINDING AFFINITY; HUMAN; HUMAN CELL; HYDROPHOBICITY; MITOCHONDRIAL TARGETING SIGNAL; MITOCHONDRION; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; APOPTOSIS; ARMADILLO DOMAIN PROTEINS; BIOLOGICAL TRANSPORT, ACTIVE; CYTOSKELETAL PROTEINS; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; MICE; MICROSCOPY, IMMUNOELECTRON; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NIH 3T3 CELLS; PROTEIN SORTING SIGNALS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TOLL-LIKE RECEPTORS;

EID: 84863178511     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111653     Document Type: Article

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