Severe energy impairment consequent to inactivation of mitochondrial ATP synthase as an early event in cell death: A mechanism for the selective sensitivity to H2O2 of differentiating erythroleukemia cells

Free Radical Biology and Medicine

Volumn 24, Issue 6, 1998, Pages 924-932

  Comelli, Marina ^a   Londero, Donatella ^b   Mavelli, Irene ^a  

^a UNIVERSITY OF UDINE   (Italy)

^b SANTA MARIA DELLA MISERICORDIA UNIVERSITY HOSPITAL   (Italy)

Author keywords

ATP; Cell death; Erythroid differentiation; Free radicals; Hydrogen peroxide; Iron overload; Mitochondrial ATP synthase; Oligomycin

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; CHELATING AGENT; HEME; HEXAMETHYLENEBISACETAMIDE; HYDROGEN PEROXIDE; IRON; IRON BINDING PROTEIN; MALONALDEHYDE; OLIGOMYCIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SCAVENGER;

AGING; ANIMAL CELL; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME INACTIVATION; ERYTHROLEUKEMIA CELL; HEME SYNTHESIS; IRON OVERLOAD; LIPID PEROXIDATION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALIA;

EID: 0032054648     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00373-0     Document Type: Article

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