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Volumn 231, Issue 4, 2016, Pages 756-767

Neurotransmitters and Neuropeptides: New Players in the Control of Islet of Langerhans' Cell Mass and Function

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; ANTIDIABETIC AGENT; BROMOCRIPTINE; DIPEPTIDYL PEPTIDASE IV INHIBITOR; DOPAMINE; DOPAMINE RECEPTOR; EXENDIN 4; GLITAZONE DERIVATIVE; GLUCAGON LIKE PEPTIDE 1; GLUTAMIC ACID; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; INSULIN; LIRAGLUTIDE; NEUROPEPTIDE; NEUROPEPTIDE RECEPTOR; NEUROPEPTIDE Y; NEUROTRANSMITTER; NEUROTRANSMITTER RECEPTOR; PEPTIDE YY; SEROTONIN; VASOACTIVE INTESTINAL POLYPEPTIDE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS;

EID: 84941299782     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.25176     Document Type: Review
Times cited : (36)

References (143)
  • 1
    • 0035135592 scopus 로고    scopus 로고
    • Distribution of vasoactive intestinal polypeptide, neuropeptide-Y and substance P and their effects on insulin secretion from the in vitro pancreas of normal and diabetic rats
    • Adeghate E, Ponery AS, Pallot DJ, Singh J. 2001. Distribution of vasoactive intestinal polypeptide, neuropeptide-Y and substance P and their effects on insulin secretion from the in vitro pancreas of normal and diabetic rats. Peptides 22:99-107.
    • (2001) Peptides , vol.22 , pp. 99-107
    • Adeghate, E.1    Ponery, A.S.2    Pallot, D.J.3    Singh, J.4
  • 2
    • 79953697662 scopus 로고    scopus 로고
    • 5-HT and the immune system
    • Ahern GP. 2011. 5-HT and the immune system. Curr Opin Pharmacol 11:29-33.
    • (2011) Curr Opin Pharmacol , vol.11 , pp. 29-33
    • Ahern, G.P.1
  • 4
    • 0345700770 scopus 로고    scopus 로고
    • Characterization of vesicular glutamate transporter in pancreatic alpha- and beta-cells and its regulation by glucose
    • Bai L, Zhang X, Ghishan FK. 2003. Characterization of vesicular glutamate transporter in pancreatic alpha- and beta-cells and its regulation by glucose. Am J Physiol Gastrointest Liver Physiol 284:G808-G814.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284 , pp. G808-G814
    • Bai, L.1    Zhang, X.2    Ghishan, F.K.3
  • 5
    • 77649190704 scopus 로고    scopus 로고
    • Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells
    • Balasubramanian R, Ruiz de Azua, I, Wess J, Jacobson KA. 2010. Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells. Biochem Pharmacol 79:1317-1326.
    • (2010) Biochem Pharmacol , vol.79 , pp. 1317-1326
    • Balasubramanian, R.1    Ruiz de Azua, I.2    Wess, J.3    Jacobson, K.A.4
  • 6
    • 79952032110 scopus 로고    scopus 로고
    • The physiology, signaling, and pharmacology of dopamine receptors
    • Beaulieu JM, Gainetdinov RR. 2011. The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol Rev 63:182-217.
    • (2011) Pharmacol Rev , vol.63 , pp. 182-217
    • Beaulieu, J.M.1    Gainetdinov, R.R.2
  • 9
    • 0027302112 scopus 로고
    • Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas
    • Bertrand G, Gross R, Puech R, Loubatières-Mariani MM, Bockaert J. 1993. Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas. Eur J Pharmacol 237:45-50.
    • (1993) Eur J Pharmacol , vol.237 , pp. 45-50
    • Bertrand, G.1    Gross, R.2    Puech, R.3    Loubatières-Mariani, M.M.4    Bockaert, J.5
  • 10
    • 0028833216 scopus 로고
    • Glutamate stimulates insulin secretion and improves glucose tolerance in rats
    • Bertrand G, Puech R, Loubatieres-Mariani MM, Bockaert J. 1995. Glutamate stimulates insulin secretion and improves glucose tolerance in rats. Am J Physiol 269:E551-E556.
    • (1995) Am J Physiol , vol.269 , pp. E551-E556
    • Bertrand, G.1    Puech, R.2    Loubatieres-Mariani, M.M.3    Bockaert, J.4
  • 11
    • 0030060951 scopus 로고    scopus 로고
    • Comparative effects of PACAP and VIP on pancreatic endocrine secretions and vascular resistance in rat
    • Bertrand G, Puech R, Maisonnasse Y, Bockaert J, Loubatières-Mariani MM. 1996. Comparative effects of PACAP and VIP on pancreatic endocrine secretions and vascular resistance in rat. Br J Pharmacol 117:764-770.
    • (1996) Br J Pharmacol , vol.117 , pp. 764-770
    • Bertrand, G.1    Puech, R.2    Maisonnasse, Y.3    Bockaert, J.4    Loubatières-Mariani, M.M.5
  • 14
    • 0033305010 scopus 로고    scopus 로고
    • Molecular and functional characterization of pituitary adenylate cyclase-activating polypeptide (PACAP-38)/vasoactive intestinal polypeptide receptors in pancreatic beta-cells and effects of PACAP-38 on components of the insulin secretory system
    • Borboni P, Porzio O, Pierucci D, Cicconi S, Magnaterra R, Federici M, Sesti G, Lauro D, D'Agata V, Cavallaro S, Marlier LN. 1999. Molecular and functional characterization of pituitary adenylate cyclase-activating polypeptide (PACAP-38)/vasoactive intestinal polypeptide receptors in pancreatic beta-cells and effects of PACAP-38 on components of the insulin secretory system. Endocrinology 140:5530-5537.
    • (1999) Endocrinology , vol.140 , pp. 5530-5537
    • Borboni, P.1    Porzio, O.2    Pierucci, D.3    Cicconi, S.4    Magnaterra, R.5    Federici, M.6    Sesti, G.7    Lauro, D.8    D'Agata, V.9    Cavallaro, S.10    Marlier, L.N.11
  • 17
    • 33847342070 scopus 로고    scopus 로고
    • Corelease and Differential Exit via the Fusion Pore of GABA, Serotonin, and ATP from LDCV in Rat Pancreatic β Cells
    • Braun M, Wendt A, Karanauskaite J, Galvanovskis J, Clark A, MacDonald PE, Rorsman P. 2007. Corelease and Differential Exit via the Fusion Pore of GABA, Serotonin, and ATP from LDCV in Rat Pancreatic β Cells. J Gen Physiol 129:221-231.
    • (2007) J Gen Physiol , vol.129 , pp. 221-231
    • Braun, M.1    Wendt, A.2    Karanauskaite, J.3    Galvanovskis, J.4    Clark, A.5    MacDonald, P.E.6    Rorsman, P.7
  • 18
    • 77954252193 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells
    • Braun M, Ramracheya R, Bengtsson M, Clark A, Walker JN, Johnson PR, Rorsman P. 2010. Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells. Diabetes 59:1694-1701.
    • (2010) Diabetes , vol.59 , pp. 1694-1701
    • Braun, M.1    Ramracheya, R.2    Bengtsson, M.3    Clark, A.4    Walker, J.N.5    Johnson, P.R.6    Rorsman, P.7
  • 19
    • 42549121680 scopus 로고    scopus 로고
    • Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells
    • Burnstock G. 2008. Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells. Pharmacol Rep. 60:12-20.
    • (2008) Pharmacol Rep. , vol.60 , pp. 12-20
    • Burnstock, G.1
  • 20
    • 84862076637 scopus 로고    scopus 로고
    • Purinergic signaling in the pancreas in health and disease
    • Burnstock G, Novak I. 2012. Purinergic signaling in the pancreas in health and disease. J Endocrinol 213:123-141.
    • (2012) J Endocrinol , vol.213 , pp. 123-141
    • Burnstock, G.1    Novak, I.2
  • 24
    • 84878808238 scopus 로고    scopus 로고
    • Pharmacology, physiology, and mechanisms of incretin hormone action
    • Campbell JE, Drucker DJ. 2013. Pharmacology, physiology, and mechanisms of incretin hormone action. Cell Metab 17:819-837.
    • (2013) Cell Metab , vol.17 , pp. 819-837
    • Campbell, J.E.1    Drucker, D.J.2
  • 25
    • 84873463641 scopus 로고    scopus 로고
    • Paracrine and autocrine interactions in the human islet: more than meets the eye
    • Caicedo A. 2013. Paracrine and autocrine interactions in the human islet: more than meets the eye. Semin Cell Dev Biol 24:11-21.
    • (2013) Semin Cell Dev Biol , vol.24 , pp. 11-21
    • Caicedo, A.1
  • 26
    • 1642578979 scopus 로고    scopus 로고
    • Neuropeptide Y promotes beta-cell replication via extracellular signal-regulated kinase activation
    • Cho YR, Kim CW. 2004. Neuropeptide Y promotes beta-cell replication via extracellular signal-regulated kinase activation. Biochem Biophys Res Commun 314:773-780.
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 773-780
    • Cho, Y.R.1    Kim, C.W.2
  • 28
    • 84862737626 scopus 로고    scopus 로고
    • The potential role glutamate in the current diabetic epidemic
    • Davalli AM, Perego C, Folli F. 2012a. The potential role glutamate in the current diabetic epidemic. Acta Diabetol 49:167-183.
    • (2012) Acta Diabetol , vol.49 , pp. 167-183
    • Davalli, A.M.1    Perego, C.2    Folli, F.3
  • 29
    • 84861700104 scopus 로고    scopus 로고
    • Long-lasting remission of type 1 diabetes following treatment with topiramate for generalized seizures
    • Davalli AM, Perego C, Folli FB, Bosi E. 2012b. Long-lasting remission of type 1 diabetes following treatment with topiramate for generalized seizures. Acta Diabetol 49:75-79.
    • (2012) Acta Diabetol , vol.49 , pp. 75-79
    • Davalli, A.M.1    Perego, C.2    Folli, F.B.3    Bosi, E.4
  • 30
    • 79956188611 scopus 로고    scopus 로고
    • Bromocriptine: a sympatholytic, D2-dopamine agonist for the treatment of type 2 diabetes
    • Defronzo RA. 2011. Bromocriptine: a sympatholytic, D2-dopamine agonist for the treatment of type 2 diabetes. Diabetes Care 34:789-794.
    • (2011) Diabetes Care , vol.34 , pp. 789-794
    • Defronzo, R.A.1
  • 31
    • 77951297946 scopus 로고    scopus 로고
    • The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the alpha2-adrenergic receptors in beta cells
    • De Leeuw van Weenen JE, Parlevliet ET, Maechler P, Havekes LM, Romijn JA, Ouwens DM, Pijl H, Guigas B. 2010. The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the alpha2-adrenergic receptors in beta cells. Biochem Pharmacol 79:1827-1836.
    • (2010) Biochem Pharmacol , vol.79 , pp. 1827-1836
    • De Leeuw van Weenen, J.E.1    Parlevliet, E.T.2    Maechler, P.3    Havekes, L.M.4    Romijn, J.A.5    Ouwens, D.M.6    Pijl, H.7    Guigas, B.8
  • 33
    • 0015134317 scopus 로고
    • Monoamines in the pancreatic islets of the mouse
    • Ekholm R, Ericson LE, Lundquist I. 1971. Monoamines in the pancreatic islets of the mouse. Diabetologia 7:339-348.
    • (1971) Diabetologia , vol.7 , pp. 339-348
    • Ekholm, R.1    Ericson, L.E.2    Lundquist, I.3
  • 35
    • 0036828227 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
    • Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U, Perfetti R. 2002. Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 143:4397-4408.
    • (2002) Endocrinology , vol.143 , pp. 4397-4408
    • Farilla, L.1    Hui, H.2    Bertolotto, C.3    Kang, E.4    Bulotta, A.5    Di Mario, U.6    Perfetti, R.7
  • 37
    • 0030953398 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans
    • Filipsson K, Tornøe K, Holst J, Ahrén B. 1997. Pituitary adenylate cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans. J Clin Endocrinol Metab 82:3093-3098.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3093-3098
    • Filipsson, K.1    Tornøe, K.2    Holst, J.3    Ahrén, B.4
  • 38
    • 0035461315 scopus 로고    scopus 로고
    • The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function
    • Filipsson K, Kvist-Reimer M, Ahrén B. 2001. The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function. Diabetes 50:1959-1969.
    • (2001) Diabetes , vol.50 , pp. 1959-1969
    • Filipsson, K.1    Kvist-Reimer, M.2    Ahrén, B.3
  • 39
    • 0037850667 scopus 로고    scopus 로고
    • Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes
    • Fineman MS, Bicsak TA, Shen LZ, Taylor K, Gaines E, Varns A, Kim D, Baron AD. 2003. Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes. Diabetes Care 26:2370-2377.
    • (2003) Diabetes Care , vol.26 , pp. 2370-2377
    • Fineman, M.S.1    Bicsak, T.A.2    Shen, L.Z.3    Taylor, K.4    Gaines, E.5    Varns, A.6    Kim, D.7    Baron, A.D.8
  • 41
    • 81555228394 scopus 로고    scopus 로고
    • Potential use of exenatide for the treatment of obesity
    • Folli F, Guardado Mendoza R. 2011. Potential use of exenatide for the treatment of obesity. Expert Opin Investig Drugs. 20:1717-1722.
    • (2011) Expert Opin Investig Drugs , vol.20 , pp. 1717-1722
    • Folli, F.1    Guardado Mendoza, R.2
  • 43
    • 84867123030 scopus 로고    scopus 로고
    • Glucagon secretion and signaling in the development of diabetes
    • Gaisano HY, Macdonald PE, Vranic M. 2012. Glucagon secretion and signaling in the development of diabetes. Front Physiol 3:349.
    • (2012) Front Physiol , vol.3 , pp. 349
    • Gaisano, H.Y.1    Macdonald, P.E.2    Vranic, M.3
  • 48
    • 38049134861 scopus 로고    scopus 로고
    • Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis
    • Gauthier BR, Duhamel DL, Iezzi M, Theander S, Saltel F, Fukuda M, Wehrle-Haller B, Wollheim CB. 2008. Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis. FASEB J 22:194-206.
    • (2008) FASEB J , vol.22 , pp. 194-206
    • Gauthier, B.R.1    Duhamel, D.L.2    Iezzi, M.3    Theander, S.4    Saltel, F.5    Fukuda, M.6    Wehrle-Haller, B.7    Wollheim, C.B.8
  • 49
    • 0036311144 scopus 로고    scopus 로고
    • Molecular determinants of regulated exocytosis
    • Gerber SH, Südhof TC. 2002. Molecular determinants of regulated exocytosis. Diabetes 51:S3-11.
    • (2002) Diabetes , vol.51 , pp. S3-11
    • Gerber, S.H.1    Südhof, T.C.2
  • 51
    • 67650659532 scopus 로고    scopus 로고
    • Purinergic P2 × 7 receptors regulate secretion of interleukin-1 receptor antagonist and beta cell function and survival
    • Glas R, Sauter NS, Schulthess FT, Shu L, Oberholzer J, Maedler K. 2009. Purinergic P2 × 7 receptors regulate secretion of interleukin-1 receptor antagonist and beta cell function and survival. Diabetologia 52:1579-1588.
    • (2009) Diabetologia , vol.52 , pp. 1579-1588
    • Glas, R.1    Sauter, N.S.2    Schulthess, F.T.3    Shu, L.4    Oberholzer, J.5    Maedler, K.6
  • 52
    • 34248333311 scopus 로고    scopus 로고
    • Therapeutical approaches of vasoactive intestinal peptide as a pleiotropic immunomodulator
    • Gonzalez-Rey E, Varela N, Chorny A, Delgado M. 2007. Therapeutical approaches of vasoactive intestinal peptide as a pleiotropic immunomodulator. Curr Pharm Des 13:1113-1139.
    • (2007) Curr Pharm Des , vol.13 , pp. 1113-1139
    • Gonzalez-Rey, E.1    Varela, N.2    Chorny, A.3    Delgado, M.4
  • 55
    • 0033982353 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide in intrinsic and extrinsic nerves of the rat pancreas
    • Hannibal J, Fahrenkrug J. 2000. Pituitary adenylate cyclase-activating polypeptide in intrinsic and extrinsic nerves of the rat pancreas. Cell Tissue Res. 299:59-70.
    • (2000) Cell Tissue Res , vol.299 , pp. 59-70
    • Hannibal, J.1    Fahrenkrug, J.2
  • 57
    • 0037449745 scopus 로고    scopus 로고
    • Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers glutamatergic signal transmission in islet of Langerhans
    • Hayashi M, Yamada H, Uehara S, Morimoto R, Muroyama A, Yatsushiro S, Takeda J, Yamamoto A, Moriyama Y. 2003a. Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers glutamatergic signal transmission in islet of Langerhans. J Biol Chem 278:1966-1974.
    • (2003) J Biol Chem , vol.278 , pp. 1966-1974
    • Hayashi, M.1    Yamada, H.2    Uehara, S.3    Morimoto, R.4    Muroyama, A.5    Yatsushiro, S.6    Takeda, J.7    Yamamoto, A.8    Moriyama, Y.9
  • 58
    • 0043268762 scopus 로고    scopus 로고
    • Vesicular inhibitory amino acid transporter is present in glucagon-containing secretory granules in alphaTC6 cells, mouse clonal alpha-cells, and alpha-cells of islets of Langerhans
    • Hayashi M, Otsuka M, Morimoto R, Muroyama A, Uehara S, Yamamoto A, Moriyama Y. 2003. Vesicular inhibitory amino acid transporter is present in glucagon-containing secretory granules in alphaTC6 cells, mouse clonal alpha-cells, and alpha-cells of islets of Langerhans. Diabetes 52:2066-2074.
    • (2003) Diabetes , vol.52 , pp. 2066-2074
    • Hayashi, M.1    Otsuka, M.2    Morimoto, R.3    Muroyama, A.4    Uehara, S.5    Yamamoto, A.6    Moriyama, Y.7
  • 59
    • 0030975613 scopus 로고    scopus 로고
    • Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas
    • Heller RS, Kieffer TJ, Habener JF. 1997. Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas. Diabetes 46:785-791.
    • (1997) Diabetes , vol.46 , pp. 785-791
    • Heller, R.S.1    Kieffer, T.J.2    Habener, J.F.3
  • 60
    • 0034007213 scopus 로고    scopus 로고
    • Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets
    • Iismaa TP, Kerr EA, Wilson JR, Carpenter L, Sims N, Biden TJ. 2000. Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets. Diabetes 49:392-398.
    • (2000) Diabetes , vol.49 , pp. 392-398
    • Iismaa, T.P.1    Kerr, E.A.2    Wilson, J.R.3    Carpenter, L.4    Sims, N.5    Biden, T.J.6
  • 63
    • 0025719222 scopus 로고
    • Peptide contents of neuropeptide Y, vasoactive intestinal polypeptide, and beta-calcitonin gene-related peptide and their messenger ribonucleic acids after dexamethasone treatment in the isolated rat islets of Langerhans
    • Jamal H, Jones PM, Byrne J, Suda K, Ghatei MA, Kanse SM, Bloom SR. 1991. Peptide contents of neuropeptide Y, vasoactive intestinal polypeptide, and beta-calcitonin gene-related peptide and their messenger ribonucleic acids after dexamethasone treatment in the isolated rat islets of Langerhans. Endocrinology 129:3372-3380.
    • (1991) Endocrinology , vol.129 , pp. 3372-3380
    • Jamal, H.1    Jones, P.M.2    Byrne, J.3    Suda, K.4    Ghatei, M.A.5    Kanse, S.M.6    Bloom, S.R.7
  • 64
    • 79952192382 scopus 로고    scopus 로고
    • Immune cell regulation by autocrine purinergic signalling
    • Junger WG. 2011. Immune cell regulation by autocrine purinergic signalling. Nat Rev Immunol 11:201-212.
    • (2011) Nat Rev Immunol , vol.11 , pp. 201-212
    • Junger, W.G.1
  • 65
    • 77953438340 scopus 로고    scopus 로고
    • Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic α-cells in mouse models of ß-cell regeneration
    • Kilimnik G, Kim A, Steiner DF, Friedman TC, Hara M. 2010. Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic α-cells in mouse models of ß-cell regeneration. Islets 2:149-155.
    • (2010) Islets , vol.2 , pp. 149-155
    • Kilimnik, G.1    Kim, A.2    Steiner, D.F.3    Friedman, T.C.4    Hara, M.5
  • 66
    • 84868196557 scopus 로고    scopus 로고
    • Paracrine interactions within islets of Langerhans
    • Koh DS, Cho JH, Chen L. 2012. Paracrine interactions within islets of Langerhans. J Mol Neurosci 48:429-440.
    • (2012) J Mol Neurosci , vol.48 , pp. 429-440
    • Koh, D.S.1    Cho, J.H.2    Chen, L.3
  • 67
    • 0030590483 scopus 로고    scopus 로고
    • Structural diversity of receptors for neuropeptides Y, peptide YY and pancreatic polypeptide
    • Larhammar D. 1996. Structural diversity of receptors for neuropeptides Y, peptide YY and pancreatic polypeptide. Regul Pept 65:165-174.
    • (1996) Regul Pept , vol.65 , pp. 165-174
    • Larhammar, D.1
  • 68
    • 33847686231 scopus 로고    scopus 로고
    • Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid
    • Ligon B, Yang J, Morin SB, Ruberti MF, Steer ML. 2007. Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid. Diabetologia 50:764-773.
    • (2007) Diabetologia , vol.50 , pp. 764-773
    • Ligon, B.1    Yang, J.2    Morin, S.B.3    Ruberti, M.F.4    Steer, M.L.5
  • 69
    • 0022979983 scopus 로고
    • Aromatic-L-amino-acid decarboxylase activity in mouse pancreatic islets
    • Lindström P. 1986. Aromatic-L-amino-acid decarboxylase activity in mouse pancreatic islets. Biochim Biophys Acta 884:276-281.
    • (1986) Biochim Biophys Acta , vol.884 , pp. 276-281
    • Lindström, P.1
  • 70
    • 0020026919 scopus 로고
    • Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem
    • Lund PK, Goodman RH, Dee PC, Habener JF. 1982. Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem. Proc Natl Acad Sci USA 79:345-349.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 345-349
    • Lund, P.K.1    Goodman, R.H.2    Dee, P.C.3    Habener, J.F.4
  • 71
    • 0025883235 scopus 로고
    • Effect of L-dopa administration on islet monoamine oxidase activity and glucose-induced insulin release in the mouse
    • Lundquist I, Panagiotidis G, Stenstrom A. 1991. Effect of L-dopa administration on islet monoamine oxidase activity and glucose-induced insulin release in the mouse. Pancreas 6:522-527.
    • (1991) Pancreas , vol.6 , pp. 522-527
    • Lundquist, I.1    Panagiotidis, G.2    Stenstrom, A.3
  • 72
    • 53749089676 scopus 로고    scopus 로고
    • Crosstalk of vascular 5-HT1 receptors with other receptors: Clinical implications
    • Maassen VanDenBrink A, Centurión D, Villalón CM. 2008. Crosstalk of vascular 5-HT1 receptors with other receptors: Clinical implications. Neuropharmacology 55:986-993.
    • (2008) Neuropharmacology , vol.55 , pp. 986-993
    • Maassen VanDenBrink, A.1    Centurión, D.2    Villalón, C.M.3
  • 73
    • 33748946239 scopus 로고    scopus 로고
    • Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β cells
    • MacDonald P, Braun M, Galvanovskis J, Rorsman P. 2006. Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β cells. Cell Metabolism 4:283-290.
    • (2006) Cell Metabolism , vol.4 , pp. 283-290
    • MacDonald, P.1    Braun, M.2    Galvanovskis, J.3    Rorsman, P.4
  • 75
    • 0033540037 scopus 로고    scopus 로고
    • Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis
    • Maechler P, Wollheim CB. 1999. Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis. Nature 402:685-689.
    • (1999) Nature , vol.402 , pp. 685-689
    • Maechler, P.1    Wollheim, C.B.2
  • 77
    • 0028349215 scopus 로고
    • Processing and metabolism of peptide-YY: Pivotal roles of dipeptidylpeptidase-IV, aminopeptidase-P, and endopeptidase-24. 11
    • Medeiros MD, Turner AJ. 1994. Processing and metabolism of peptide-YY: Pivotal roles of dipeptidylpeptidase-IV, aminopeptidase-P, and endopeptidase-24. 11. Endocrinology 134:2088-2094.
    • (1994) Endocrinology , vol.134 , pp. 2088-2094
    • Medeiros, M.D.1    Turner, A.J.2
  • 79
    • 0024498654 scopus 로고
    • Metabolite-regulated ATP-sensitive K+ channel in human pancreatic islet cells
    • Misler S, Gee WM, Gillis KD, Scharp DW, Falke LC. 1989. Metabolite-regulated ATP-sensitive K+ channel in human pancreatic islet cells. Diabetes 38:422-427.
    • (1989) Diabetes , vol.38 , pp. 422-427
    • Misler, S.1    Gee, W.M.2    Gillis, K.D.3    Scharp, D.W.4    Falke, L.C.5
  • 80
    • 13344293675 scopus 로고    scopus 로고
    • Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells
    • Moens K, Heimberg H, Flamez D, Huypens P, Quartier E, Ling Z, Pipeleers D, Gremlich S, Thorens B, Schuit F. 1996. Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. Diabetes 45:257-261.
    • (1996) Diabetes , vol.45 , pp. 257-261
    • Moens, K.1    Heimberg, H.2    Flamez, D.3    Huypens, P.4    Quartier, E.5    Ling, Z.6    Pipeleers, D.7    Gremlich, S.8    Thorens, B.9    Schuit, F.10
  • 82
    • 0031797940 scopus 로고    scopus 로고
    • Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenyl cyclase in RIN 5AH rat insulinoma cells
    • Morgan DG, Kulkarni RN, Hurley JD, Wang ZL, Wang RM, Ghatei MA, Karlsen AE, Bloom SR, Smith DM. 1998. Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenyl cyclase in RIN 5AH rat insulinoma cells. Diabetologia 41:1482-1491.
    • (1998) Diabetologia , vol.41 , pp. 1482-1491
    • Morgan, D.G.1    Kulkarni, R.N.2    Hurley, J.D.3    Wang, Z.L.4    Wang, R.M.5    Ghatei, M.A.6    Karlsen, A.E.7    Bloom, S.R.8    Smith, D.M.9
  • 83
    • 0141987898 scopus 로고    scopus 로고
    • Glutamate-mediated signaling in the islets of Langerhans: a thread entangled
    • Moriyama Y, Hayashi M. 2003. Glutamate-mediated signaling in the islets of Langerhans: a thread entangled. Trends Pharmacol Sci 24:511-517.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 511-517
    • Moriyama, Y.1    Hayashi, M.2
  • 85
    • 0028845585 scopus 로고
    • Neuropeptide Y is expressed in subpopulations of insulin- and non-insulin-producing islet cells in the rat after dexamethasone treatment: A combined immunocytochemical and in situ hybridisation study
    • Myrsén U, Ahrén B, Sundler F. 1995. Neuropeptide Y is expressed in subpopulations of insulin- and non-insulin-producing islet cells in the rat after dexamethasone treatment: A combined immunocytochemical and in situ hybridisation study. Regul Pept 60:19-31.
    • (1995) Regul Pept , vol.60 , pp. 19-31
    • Myrsén, U.1    Ahrén, B.2    Sundler, F.3
  • 86
    • 78349310241 scopus 로고    scopus 로고
    • Intra-islet PACAP protects pancreatic β-cells against glucotoxicity and lipotoxicity
    • Nakata M, Shintani N, Hashimoto H, Baba A, Yada T. 2010. Intra-islet PACAP protects pancreatic β-cells against glucotoxicity and lipotoxicity. J Mol Neurosci 42:404-410.
    • (2010) J Mol Neurosci , vol.42 , pp. 404-410
    • Nakata, M.1    Shintani, N.2    Hashimoto, H.3    Baba, A.4    Yada, T.5
  • 92
    • 0036721026 scopus 로고    scopus 로고
    • Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4
    • Perry T, Haughey NJ, Mattson MP, Egan JM, Greig NH. 2002. Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4. J Pharmacol Exp Ther 302:881-888.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 881-888
    • Perry, T.1    Haughey, N.J.2    Mattson, M.P.3    Egan, J.M.4    Greig, N.H.5
  • 93
    • 62649114002 scopus 로고    scopus 로고
    • P2 purinergic signaling in the pancreatic beta-cell: control of insulin secretion and pharmacology
    • Petit P, Lajoix AD, Gross R. 2009. P2 purinergic signaling in the pancreatic beta-cell: control of insulin secretion and pharmacology. Eur J Pharm Sci 37:67-75.
    • (2009) Eur J Pharm Sci , vol.37 , pp. 67-75
    • Petit, P.1    Lajoix, A.D.2    Gross, R.3
  • 95
    • 0037447728 scopus 로고    scopus 로고
    • PACAP is expressed in secretory granules of insulin and glucagon cells in human and rodent pancreas. Evidence for generation of cAMP compartments uncoupled from hormone release in diabetic islets
    • Portela-Gomes GM, Lukinius A, Ljungberg O, Efendic S, Ahrén B, Abdel-Halim SM. 2003. PACAP is expressed in secretory granules of insulin and glucagon cells in human and rodent pancreas. Evidence for generation of cAMP compartments uncoupled from hormone release in diabetic islets. Regul Pept 113:31-39.
    • (2003) Regul Pept , vol.113 , pp. 31-39
    • Portela-Gomes, G.M.1    Lukinius, A.2    Ljungberg, O.3    Efendic, S.4    Ahrén, B.5    Abdel-Halim, S.M.6
  • 97
    • 0025875235 scopus 로고
    • GABA and pancreatic beta-cells: Colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion
    • Reetz A, Solimena M, Matteoli M, Folli F, Takei K, De Camilli P. 1991. GABA and pancreatic beta-cells: Colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion. EMBO J 10:1275-1284.
    • (1991) EMBO J , vol.10 , pp. 1275-1284
    • Reetz, A.1    Solimena, M.2    Matteoli, M.3    Folli, F.4    Takei, K.5    De Camilli, P.6
  • 103
    • 84873670723 scopus 로고    scopus 로고
    • Regulation of insulin secretion in human pancreatic islets
    • Rorsman P, Braun M. 2013. Regulation of insulin secretion in human pancreatic islets. Annu Rev Physiol 75:155-179.
    • (2013) Annu Rev Physiol , vol.75 , pp. 155-179
    • Rorsman, P.1    Braun, M.2
  • 104
    • 34249899669 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of topiramate controlled release in the treatment of obese type 2 diabetic patients
    • OBD-202 Study Group
    • Rosenstock J, Hollander P, Gadde KM, Sun X, Strauss R, Leung A, OBD-202 Study Group. 2007. A randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of topiramate controlled release in the treatment of obese type 2 diabetic patients. Diabetes Care 30:1480-1486.
    • (2007) Diabetes Care , vol.30 , pp. 1480-1486
    • Rosenstock, J.1    Hollander, P.2    Gadde, K.M.3    Sun, X.4    Strauss, R.5    Leung, A.6
  • 105
    • 27744588806 scopus 로고    scopus 로고
    • Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion
    • Rubì B, Ljubicic S, Pournourmohammadi S, Carobbio S, Armanet M, Bartley C, Maechler P. 2005. Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion. J Biol Chem 280:36824-36832.
    • (2005) J Biol Chem , vol.280 , pp. 36824-36832
    • Rubì, B.1    Ljubicic, S.2    Pournourmohammadi, S.3    Carobbio, S.4    Armanet, M.5    Bartley, C.6    Maechler, P.7
  • 106
    • 33744492048 scopus 로고    scopus 로고
    • Insulin vesicle release: walk, kiss, pause then run
    • Rutter GA, Hill EV. 2006. Insulin vesicle release: walk, kiss, pause then run. Physiology 21:189-196.
    • (2006) Physiology , vol.21 , pp. 189-196
    • Rutter, G.A.1    Hill, E.V.2
  • 111
    • 0031922709 scopus 로고    scopus 로고
    • Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling
    • Scrocchi LA, Marshall BA, Cook SM, Brubaker PL, Drucker DJ. 1998. Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling. Diabetes 47:632-639.
    • (1998) Diabetes , vol.47 , pp. 632-639
    • Scrocchi, L.A.1    Marshall, B.A.2    Cook, S.M.3    Brubaker, P.L.4    Drucker, D.J.5
  • 112
    • 33646857967 scopus 로고    scopus 로고
    • Dopaminergic regulation of glucose-induced insulin secretion through dopamine D2 receptors in the pancreatic islets in vitro
    • Shankar E, Santhosh KT, Paulose CS. 2006. Dopaminergic regulation of glucose-induced insulin secretion through dopamine D2 receptors in the pancreatic islets in vitro. IUBMB Life. 58:157-163.
    • (2006) IUBMB Life. , vol.58 , pp. 157-163
    • Shankar, E.1    Santhosh, K.T.2    Paulose, C.S.3
  • 113
  • 115
    • 0035313223 scopus 로고    scopus 로고
    • Glutamate signaling in non-neuronal tissues
    • Skerry TM, Genever PG. 2001. Glutamate signaling in non-neuronal tissues. Trends Pharmacol Sci 22:174-181.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 174-181
    • Skerry, T.M.1    Genever, P.G.2
  • 117
    • 77955551862 scopus 로고    scopus 로고
    • Voltage-dependent K(+) channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans
    • Spigelman AF, Dai X, MacDonald PE. 2010. Voltage-dependent K(+) channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans. Diabetologia 53:1917-1926.
    • (2010) Diabetologia , vol.53 , pp. 1917-1926
    • Spigelman, A.F.1    Dai, X.2    MacDonald, P.E.3
  • 118
    • 0026505528 scopus 로고
    • The vascular order of islet cellular perfusion in the human pancreas
    • Stagner JI, Samols E. 1992. The vascular order of islet cellular perfusion in the human pancreas. Diabetes 41:93-97.
    • (1992) Diabetes , vol.41 , pp. 93-97
    • Stagner, J.I.1    Samols, E.2
  • 119
    • 79960262492 scopus 로고    scopus 로고
    • Management of type 2 diabetes: new and future developments in treatment
    • Tahrani AA, Bailey CJ, Del Prato S, Barnett AH. 2011. Management of type 2 diabetes: new and future developments in treatment. Lancet 378:182-197.
    • (2011) Lancet , vol.378 , pp. 182-197
    • Tahrani, A.A.1    Bailey, C.J.2    Del Prato, S.3    Barnett, A.H.4
  • 120
    • 0019944850 scopus 로고
    • Neuropeptide Y a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide
    • Tatemoto K, Carlquist M, Mutt V. 1982. Neuropeptide Y a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide. Nature 296:659-660.
    • (1982) Nature , vol.296 , pp. 659-660
    • Tatemoto, K.1    Carlquist, M.2    Mutt, V.3
  • 121
    • 0027265223 scopus 로고
    • A gamma-aminobutyric acid transporter driven by a proton pump is present in synaptic-like microvesicles of pancreatic beta cells
    • Thomas-Reetz A, Hell JW, During MJ, Walch-Solimena C, Jahn R, De Camilli P. 1993. A gamma-aminobutyric acid transporter driven by a proton pump is present in synaptic-like microvesicles of pancreatic beta cells. Proc Natl Acad Sci USA 90:5317-5321.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5317-5321
    • Thomas-Reetz, A.1    Hell, J.W.2    During, M.J.3    Walch-Solimena, C.4    Jahn, R.5    De Camilli, P.6
  • 122
    • 80053078763 scopus 로고    scopus 로고
    • Oral treatment with gamma-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice
    • Tian J, Dang HN, Yong J, Kaufman DL. 2011. Oral treatment with gamma-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice. PLoS ONE 6:e25338.
    • (2011) PLoS ONE , vol.6 , pp. e25338
    • Tian, J.1    Dang, H.N.2    Yong, J.3    Kaufman, D.L.4
  • 123
    • 84891715964 scopus 로고    scopus 로고
    • γ-Aminobutyric acid regulates both the survival and replication of human β-cells
    • Tian J, Dang H, Chen Z, Guan A, Jin Y, Atkinson MA, Kaufman DL. 2013. γ-Aminobutyric acid regulates both the survival and replication of human β-cells. Diabetes 62:3760-3765.
    • (2013) Diabetes , vol.62 , pp. 3760-3765
    • Tian, J.1    Dang, H.2    Chen, Z.3    Guan, A.4    Jin, Y.5    Atkinson, M.A.6    Kaufman, D.L.7
  • 126
    • 1842423000 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor type 4 is involved in autoinhibitory cascade for glucagon secretion by alpha-cells of islet of Langerhans
    • Uehara S, Muroyama A, Echigo N, Morimoto R, Otsuka M, Yatsushiro S, Moriyama Y. 2004. Metabotropic glutamate receptor type 4 is involved in autoinhibitory cascade for glucagon secretion by alpha-cells of islet of Langerhans. Diabetes 53:998-1006.
    • (2004) Diabetes , vol.53 , pp. 998-1006
    • Uehara, S.1    Muroyama, A.2    Echigo, N.3    Morimoto, R.4    Otsuka, M.5    Yatsushiro, S.6    Moriyama, Y.7
  • 127
    • 84868129185 scopus 로고    scopus 로고
    • Dopamine synthesis and D3 receptor activation in pancreatic β-cells regulates insulin secretion and intracellular [Ca(2+)] oscillations
    • Ustione A, Piston DW. 2012. Dopamine synthesis and D3 receptor activation in pancreatic β-cells regulates insulin secretion and intracellular [Ca(2+)] oscillations. Mol Endocrinol 11:1928-1940.
    • (2012) Mol Endocrinol , vol.11 , pp. 1928-1940
    • Ustione, A.1    Piston, D.W.2
  • 129
    • 12144283149 scopus 로고    scopus 로고
    • Comparison of cellular and medium insulin and GABA content as markers for living beta-cells
    • Wang C, Ling Z, Pipeleers D. 2005. Comparison of cellular and medium insulin and GABA content as markers for living beta-cells. Am J Physiol Endocrinol Metab 288:E307-E313.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. E307-E313
    • Wang, C.1    Ling, Z.2    Pipeleers, D.3
  • 131
    • 0030470550 scopus 로고    scopus 로고
    • Multiple human receptors for pituitary adenylyl cyclase-activating polypeptide and vasoactive intestinal peptide are expressed in a tissue-specific manner
    • Wei Y, Mojsov S. 1996. Multiple human receptors for pituitary adenylyl cyclase-activating polypeptide and vasoactive intestinal peptide are expressed in a tissue-specific manner. Ann N Y Acad Sci 805:624-627.
    • (1996) Ann N Y Acad Sci , vol.805 , pp. 624-627
    • Wei, Y.1    Mojsov, S.2
  • 132
    • 84856655849 scopus 로고    scopus 로고
    • Activation of muscarinic receptors by non-neuronal acetylcholine
    • Wessler IK, Kirkpatrick CJ. 2012. Activation of muscarinic receptors by non-neuronal acetylcholine. Handb Exp Pharmacol 208:469-491.
    • (2012) Handb Exp Pharmacol , vol.208 , pp. 469-491
    • Wessler, I.K.1    Kirkpatrick, C.J.2
  • 133
    • 79955768520 scopus 로고    scopus 로고
    • Pancreatic beta cells synthesize neuropeptide Y and can rapidly release peptide co-transmitters
    • Whim MD. 2011. Pancreatic beta cells synthesize neuropeptide Y and can rapidly release peptide co-transmitters. PLoS ONE 6:e19478.
    • (2011) PLoS ONE , vol.6 , pp. e19478
    • Whim, M.D.1
  • 135
    • 35748962950 scopus 로고    scopus 로고
    • A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice
    • Wideman RD, Covey SD, Webb GC, Drucker DJ, Kieffer TJ. 2007. A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice. Diabetes 56:2744-2752.
    • (2007) Diabetes , vol.56 , pp. 2744-2752
    • Wideman, R.D.1    Covey, S.D.2    Webb, G.C.3    Drucker, D.J.4    Kieffer, T.J.5
  • 137
    • 0028054862 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells
    • Yada T, Sakurada M, Ihida K, Nakata M, Murata F, Arimura A, Kikuchi M. 1994. Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells. J Biol Chem 269:1290-1293.
    • (1994) J Biol Chem , vol.269 , pp. 1290-1293
    • Yada, T.1    Sakurada, M.2    Ihida, K.3    Nakata, M.4    Murata, F.5    Arimura, A.6    Kikuchi, M.7
  • 138
    • 0031449347 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet substance serving as an intra-islet amplifier of glucose-induced insulin secretion in rats
    • Yada T, Sakurada M, Ishihara H, Nakata M, Shioda S, Yaekura K, Hamakawa N, Yanagida K, Kikuchi M, Oka Y. 1997. Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet substance serving as an intra-islet amplifier of glucose-induced insulin secretion in rats. J Physiol 505:319-328.
    • (1997) J Physiol , vol.505 , pp. 319-328
    • Yada, T.1    Sakurada, M.2    Ishihara, H.3    Nakata, M.4    Shioda, S.5    Yaekura, K.6    Hamakawa, N.7    Yanagida, K.8    Kikuchi, M.9    Oka, Y.10
  • 139
    • 7044222788 scopus 로고    scopus 로고
    • Cytosolic Ca2+ responses to sub-picomolar and nanomolar PACAP in pancreatic beta-cells are mediated by VPAC2 and PAC1 receptors
    • Yamada H, Watanabe M, Yada T. 2004. Cytosolic Ca2+ responses to sub-picomolar and nanomolar PACAP in pancreatic beta-cells are mediated by VPAC2 and PAC1 receptors. Regul Pept 123:147-153.
    • (2004) Regul Pept , vol.123 , pp. 147-153
    • Yamada, H.1    Watanabe, M.2    Yada, T.3
  • 141
    • 12944302589 scopus 로고    scopus 로고
    • Evidence for functional nicotinic receptors on pancreatic beta cells
    • Yoshikawa H, Hellström-Lindahl E, Grill V. 2005. Evidence for functional nicotinic receptors on pancreatic beta cells. Metabolism 54:247-254.
    • (2005) Metabolism , vol.54 , pp. 247-254
    • Yoshikawa, H.1    Hellström-Lindahl, E.2    Grill, V.3
  • 143
    • 84937904927 scopus 로고    scopus 로고
    • Pancreatic endocrine effects of dopamine receptors in human islet cells
    • Zhang Y, Zheng R, Meng X, Wang L, Liu L, Gao Y. 2015. Pancreatic endocrine effects of dopamine receptors in human islet cells. Pancreas 44:925-929.
    • (2015) Pancreas , vol.44 , pp. 925-929
    • Zhang, Y.1    Zheng, R.2    Meng, X.3    Wang, L.4    Liu, L.5    Gao, Y.6


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