-
1
-
-
0035135592
-
Distribution of vasoactive intestinal polypeptide, neuropeptide-Y and substance P and their effects on insulin secretion from the in vitro pancreas of normal and diabetic rats
-
Adeghate E, Ponery AS, Pallot DJ, Singh J. 2001. Distribution of vasoactive intestinal polypeptide, neuropeptide-Y and substance P and their effects on insulin secretion from the in vitro pancreas of normal and diabetic rats. Peptides 22:99-107.
-
(2001)
Peptides
, vol.22
, pp. 99-107
-
-
Adeghate, E.1
Ponery, A.S.2
Pallot, D.J.3
Singh, J.4
-
2
-
-
79953697662
-
5-HT and the immune system
-
Ahern GP. 2011. 5-HT and the immune system. Curr Opin Pharmacol 11:29-33.
-
(2011)
Curr Opin Pharmacol
, vol.11
, pp. 29-33
-
-
Ahern, G.P.1
-
3
-
-
84862001481
-
Adenosine signaling promotes regeneration of pancreatic b cells in vivo
-
Andersson O, Adams BA, Yoo D, Ellis GC, Gut P, Anderson RM, German MS, Stainier DY. 2012. Adenosine signaling promotes regeneration of pancreatic b cells in vivo. Cell Metab 15:885-894.
-
(2012)
Cell Metab
, vol.15
, pp. 885-894
-
-
Andersson, O.1
Adams, B.A.2
Yoo, D.3
Ellis, G.C.4
Gut, P.5
Anderson, R.M.6
German, M.S.7
Stainier, D.Y.8
-
4
-
-
0345700770
-
Characterization of vesicular glutamate transporter in pancreatic alpha- and beta-cells and its regulation by glucose
-
Bai L, Zhang X, Ghishan FK. 2003. Characterization of vesicular glutamate transporter in pancreatic alpha- and beta-cells and its regulation by glucose. Am J Physiol Gastrointest Liver Physiol 284:G808-G814.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
, pp. G808-G814
-
-
Bai, L.1
Zhang, X.2
Ghishan, F.K.3
-
5
-
-
77649190704
-
Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells
-
Balasubramanian R, Ruiz de Azua, I, Wess J, Jacobson KA. 2010. Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells. Biochem Pharmacol 79:1317-1326.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 1317-1326
-
-
Balasubramanian, R.1
Ruiz de Azua, I.2
Wess, J.3
Jacobson, K.A.4
-
6
-
-
79952032110
-
The physiology, signaling, and pharmacology of dopamine receptors
-
Beaulieu JM, Gainetdinov RR. 2011. The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol Rev 63:182-217.
-
(2011)
Pharmacol Rev
, vol.63
, pp. 182-217
-
-
Beaulieu, J.M.1
Gainetdinov, R.R.2
-
8
-
-
0029884701
-
Presence of neuropeptide Y and its messenger ribonucleic acid in human islets: evidence for a possible paracrine role
-
Bennet WM, Wang ZL, Jones PM, Wang RM, James RF, London NJ, Ghatei MA, Bloom SR. 1996. Presence of neuropeptide Y and its messenger ribonucleic acid in human islets: evidence for a possible paracrine role. J Clin Endocrinol Metab 81:2117-2120.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 2117-2120
-
-
Bennet, W.M.1
Wang, Z.L.2
Jones, P.M.3
Wang, R.M.4
James, R.F.5
London, N.J.6
Ghatei, M.A.7
Bloom, S.R.8
-
9
-
-
0027302112
-
Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas
-
Bertrand G, Gross R, Puech R, Loubatières-Mariani MM, Bockaert J. 1993. Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas. Eur J Pharmacol 237:45-50.
-
(1993)
Eur J Pharmacol
, vol.237
, pp. 45-50
-
-
Bertrand, G.1
Gross, R.2
Puech, R.3
Loubatières-Mariani, M.M.4
Bockaert, J.5
-
10
-
-
0028833216
-
Glutamate stimulates insulin secretion and improves glucose tolerance in rats
-
Bertrand G, Puech R, Loubatieres-Mariani MM, Bockaert J. 1995. Glutamate stimulates insulin secretion and improves glucose tolerance in rats. Am J Physiol 269:E551-E556.
-
(1995)
Am J Physiol
, vol.269
, pp. E551-E556
-
-
Bertrand, G.1
Puech, R.2
Loubatieres-Mariani, M.M.3
Bockaert, J.4
-
11
-
-
0030060951
-
Comparative effects of PACAP and VIP on pancreatic endocrine secretions and vascular resistance in rat
-
Bertrand G, Puech R, Maisonnasse Y, Bockaert J, Loubatières-Mariani MM. 1996. Comparative effects of PACAP and VIP on pancreatic endocrine secretions and vascular resistance in rat. Br J Pharmacol 117:764-770.
-
(1996)
Br J Pharmacol
, vol.117
, pp. 764-770
-
-
Bertrand, G.1
Puech, R.2
Maisonnasse, Y.3
Bockaert, J.4
Loubatières-Mariani, M.M.5
-
12
-
-
0018841085
-
The location of VIP in the pancreas of man and rat
-
Bishop AE, Polak JM, Green IC, Bryant MG, Bloom SR. 1980. The location of VIP in the pancreas of man and rat. Diabetologia 18:73-78.
-
(1980)
Diabetologia
, vol.18
, pp. 73-78
-
-
Bishop, A.E.1
Polak, J.M.2
Green, I.C.3
Bryant, M.G.4
Bloom, S.R.5
-
13
-
-
38349016310
-
GABAB receptors and glucose homeostasis: evaluation in GABAB receptor knockout mice
-
Bonaventura MM, Catalano PN, Chamson-Reig A, Arany E, Hill D, Bettler B, Saravia F, Libertun C, Lux-Lantos VA. 2008. GABAB receptors and glucose homeostasis: evaluation in GABAB receptor knockout mice. Am J Physiol Endocrinol Metab 294:E157-E167.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
, pp. E157-E167
-
-
Bonaventura, M.M.1
Catalano, P.N.2
Chamson-Reig, A.3
Arany, E.4
Hill, D.5
Bettler, B.6
Saravia, F.7
Libertun, C.8
Lux-Lantos, V.A.9
-
14
-
-
0033305010
-
Molecular and functional characterization of pituitary adenylate cyclase-activating polypeptide (PACAP-38)/vasoactive intestinal polypeptide receptors in pancreatic beta-cells and effects of PACAP-38 on components of the insulin secretory system
-
Borboni P, Porzio O, Pierucci D, Cicconi S, Magnaterra R, Federici M, Sesti G, Lauro D, D'Agata V, Cavallaro S, Marlier LN. 1999. Molecular and functional characterization of pituitary adenylate cyclase-activating polypeptide (PACAP-38)/vasoactive intestinal polypeptide receptors in pancreatic beta-cells and effects of PACAP-38 on components of the insulin secretory system. Endocrinology 140:5530-5537.
-
(1999)
Endocrinology
, vol.140
, pp. 5530-5537
-
-
Borboni, P.1
Porzio, O.2
Pierucci, D.3
Cicconi, S.4
Magnaterra, R.5
Federici, M.6
Sesti, G.7
Lauro, D.8
D'Agata, V.9
Cavallaro, S.10
Marlier, L.N.11
-
15
-
-
77951853210
-
Unique arrangement of alpha- and beta-cells in human islets of Langerhans
-
Bosco D, Armanet M, Morel P, Niclauss N, Sgroi A, Muller YD, Giovannoni L, Parnaud G, Berney T. 2010. Unique arrangement of alpha- and beta-cells in human islets of Langerhans. Diabetes 59:1202-1210.
-
(2010)
Diabetes
, vol.59
, pp. 1202-1210
-
-
Bosco, D.1
Armanet, M.2
Morel, P.3
Niclauss, N.4
Sgroi, A.5
Muller, Y.D.6
Giovannoni, L.7
Parnaud, G.8
Berney, T.9
-
16
-
-
1442358665
-
Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic β-cells
-
Braun M, Wendt A, Birnir B, Broman J, Eliasson L, Galvanovskis J, Gromada J, Mulder H, Rorsman P. 2004. Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic β-cells. J Gen Physiol 123:191-204.
-
(2004)
J Gen Physiol
, vol.123
, pp. 191-204
-
-
Braun, M.1
Wendt, A.2
Birnir, B.3
Broman, J.4
Eliasson, L.5
Galvanovskis, J.6
Gromada, J.7
Mulder, H.8
Rorsman, P.9
-
17
-
-
33847342070
-
Corelease and Differential Exit via the Fusion Pore of GABA, Serotonin, and ATP from LDCV in Rat Pancreatic β Cells
-
Braun M, Wendt A, Karanauskaite J, Galvanovskis J, Clark A, MacDonald PE, Rorsman P. 2007. Corelease and Differential Exit via the Fusion Pore of GABA, Serotonin, and ATP from LDCV in Rat Pancreatic β Cells. J Gen Physiol 129:221-231.
-
(2007)
J Gen Physiol
, vol.129
, pp. 221-231
-
-
Braun, M.1
Wendt, A.2
Karanauskaite, J.3
Galvanovskis, J.4
Clark, A.5
MacDonald, P.E.6
Rorsman, P.7
-
18
-
-
77954252193
-
Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells
-
Braun M, Ramracheya R, Bengtsson M, Clark A, Walker JN, Johnson PR, Rorsman P. 2010. Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells. Diabetes 59:1694-1701.
-
(2010)
Diabetes
, vol.59
, pp. 1694-1701
-
-
Braun, M.1
Ramracheya, R.2
Bengtsson, M.3
Clark, A.4
Walker, J.N.5
Johnson, P.R.6
Rorsman, P.7
-
19
-
-
42549121680
-
Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells
-
Burnstock G. 2008. Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells. Pharmacol Rep. 60:12-20.
-
(2008)
Pharmacol Rep.
, vol.60
, pp. 12-20
-
-
Burnstock, G.1
-
20
-
-
84862076637
-
Purinergic signaling in the pancreas in health and disease
-
Burnstock G, Novak I. 2012. Purinergic signaling in the pancreas in health and disease. J Endocrinol 213:123-141.
-
(2012)
J Endocrinol
, vol.213
, pp. 123-141
-
-
Burnstock, G.1
Novak, I.2
-
21
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. 2003. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 52:102-110.
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
22
-
-
33144467088
-
The unique cytoarchitecture of human pancreatic islets has implications for islet cell function
-
Cabrera O, Berman DM, Kenyon NS, Ricordi C, Berggren PO, Caicedo A. 2006. The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci USA 103:2334-2339.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2334-2339
-
-
Cabrera, O.1
Berman, D.M.2
Kenyon, N.S.3
Ricordi, C.4
Berggren, P.O.5
Caicedo, A.6
-
23
-
-
44349176043
-
Glutamate Is a Positive Autocrine Signal for Glucagon Release
-
Cabrera O, Jacques-Silva MC, Speier S, Yang SN, Köhler M, Fachado A, Vieira E, Zierath JR, Kibbey R, Berman DM, Kenyon NS, Ricordi C, Caicedo A, Berggren PO. 2008. Glutamate Is a Positive Autocrine Signal for Glucagon Release. Cell Metab 7:545-554.
-
(2008)
Cell Metab
, vol.7
, pp. 545-554
-
-
Cabrera, O.1
Jacques-Silva, M.C.2
Speier, S.3
Yang, S.N.4
Köhler, M.5
Fachado, A.6
Vieira, E.7
Zierath, J.R.8
Kibbey, R.9
Berman, D.M.10
Kenyon, N.S.11
Ricordi, C.12
Caicedo, A.13
Berggren, P.O.14
-
24
-
-
84878808238
-
Pharmacology, physiology, and mechanisms of incretin hormone action
-
Campbell JE, Drucker DJ. 2013. Pharmacology, physiology, and mechanisms of incretin hormone action. Cell Metab 17:819-837.
-
(2013)
Cell Metab
, vol.17
, pp. 819-837
-
-
Campbell, J.E.1
Drucker, D.J.2
-
25
-
-
84873463641
-
Paracrine and autocrine interactions in the human islet: more than meets the eye
-
Caicedo A. 2013. Paracrine and autocrine interactions in the human islet: more than meets the eye. Semin Cell Dev Biol 24:11-21.
-
(2013)
Semin Cell Dev Biol
, vol.24
, pp. 11-21
-
-
Caicedo, A.1
-
26
-
-
1642578979
-
Neuropeptide Y promotes beta-cell replication via extracellular signal-regulated kinase activation
-
Cho YR, Kim CW. 2004. Neuropeptide Y promotes beta-cell replication via extracellular signal-regulated kinase activation. Biochem Biophys Res Commun 314:773-780.
-
(2004)
Biochem Biophys Res Commun
, vol.314
, pp. 773-780
-
-
Cho, Y.R.1
Kim, C.W.2
-
27
-
-
84923212941
-
Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis
-
Crane JD, Palanivel R, Mottillo EP, Bujak AL, Wang H, Ford RJ, Collins A, Blümer RM, Fullerton MD, Yabut JM, Kim JJ, Ghia JE, Hamza SM, Morrison KM, Schertzer JD, Dyck JR, Khan WI, Steinberg GR. 2015. Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis. Nat Med 21:166-172.
-
(2015)
Nat Med
, vol.21
, pp. 166-172
-
-
Crane, J.D.1
Palanivel, R.2
Mottillo, E.P.3
Bujak, A.L.4
Wang, H.5
Ford, R.J.6
Collins, A.7
Blümer, R.M.8
Fullerton, M.D.9
Yabut, J.M.10
Kim, J.J.11
Ghia, J.E.12
Hamza, S.M.13
Morrison, K.M.14
Schertzer, J.D.15
Dyck, J.R.16
Khan, W.I.17
Steinberg, G.R.18
-
28
-
-
84862737626
-
The potential role glutamate in the current diabetic epidemic
-
Davalli AM, Perego C, Folli F. 2012a. The potential role glutamate in the current diabetic epidemic. Acta Diabetol 49:167-183.
-
(2012)
Acta Diabetol
, vol.49
, pp. 167-183
-
-
Davalli, A.M.1
Perego, C.2
Folli, F.3
-
29
-
-
84861700104
-
Long-lasting remission of type 1 diabetes following treatment with topiramate for generalized seizures
-
Davalli AM, Perego C, Folli FB, Bosi E. 2012b. Long-lasting remission of type 1 diabetes following treatment with topiramate for generalized seizures. Acta Diabetol 49:75-79.
-
(2012)
Acta Diabetol
, vol.49
, pp. 75-79
-
-
Davalli, A.M.1
Perego, C.2
Folli, F.B.3
Bosi, E.4
-
30
-
-
79956188611
-
Bromocriptine: a sympatholytic, D2-dopamine agonist for the treatment of type 2 diabetes
-
Defronzo RA. 2011. Bromocriptine: a sympatholytic, D2-dopamine agonist for the treatment of type 2 diabetes. Diabetes Care 34:789-794.
-
(2011)
Diabetes Care
, vol.34
, pp. 789-794
-
-
Defronzo, R.A.1
-
31
-
-
77951297946
-
The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the alpha2-adrenergic receptors in beta cells
-
De Leeuw van Weenen JE, Parlevliet ET, Maechler P, Havekes LM, Romijn JA, Ouwens DM, Pijl H, Guigas B. 2010. The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the alpha2-adrenergic receptors in beta cells. Biochem Pharmacol 79:1827-1836.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 1827-1836
-
-
De Leeuw van Weenen, J.E.1
Parlevliet, E.T.2
Maechler, P.3
Havekes, L.M.4
Romijn, J.A.5
Ouwens, D.M.6
Pijl, H.7
Guigas, B.8
-
32
-
-
79954570143
-
The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death
-
Di Cairano ES, Davalli AM, Perego L, Sala S, Sacchi VF, La Rosa S, Finzi G, Placidi C, Capella C, Conti P, Centonze VE, Casiraghi F, Bertuzzi F, Folli F, Perego C. 2011. The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death. J Biol Chem 286:14007-14018.
-
(2011)
J Biol Chem
, vol.286
, pp. 14007-14018
-
-
Di Cairano, E.S.1
Davalli, A.M.2
Perego, L.3
Sala, S.4
Sacchi, V.F.5
La Rosa, S.6
Finzi, G.7
Placidi, C.8
Capella, C.9
Conti, P.10
Centonze, V.E.11
Casiraghi, F.12
Bertuzzi, F.13
Folli, F.14
Perego, C.15
-
33
-
-
0015134317
-
Monoamines in the pancreatic islets of the mouse
-
Ekholm R, Ericson LE, Lundquist I. 1971. Monoamines in the pancreatic islets of the mouse. Diabetologia 7:339-348.
-
(1971)
Diabetologia
, vol.7
, pp. 339-348
-
-
Ekholm, R.1
Ericson, L.E.2
Lundquist, I.3
-
34
-
-
0034982387
-
High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program
-
Federici M, Hribal M, Perego L, Ranalli M, Caradonna Z, Perego C, Usellini L, Nano R, Bonini P, Bertuzzi F, Marlier LN, Davalli AM, Carandente O, Pontiroli AE, Melino G, Marchetti P, Lauro R, Sesti G, Folli F. 2001. High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program. Diabetes 50:1290-1301.
-
(2001)
Diabetes
, vol.50
, pp. 1290-1301
-
-
Federici, M.1
Hribal, M.2
Perego, L.3
Ranalli, M.4
Caradonna, Z.5
Perego, C.6
Usellini, L.7
Nano, R.8
Bonini, P.9
Bertuzzi, F.10
Marlier, L.N.11
Davalli, A.M.12
Carandente, O.13
Pontiroli, A.E.14
Melino, G.15
Marchetti, P.16
Lauro, R.17
Sesti, G.18
Folli, F.19
-
35
-
-
0036828227
-
Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
-
Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U, Perfetti R. 2002. Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 143:4397-4408.
-
(2002)
Endocrinology
, vol.143
, pp. 4397-4408
-
-
Farilla, L.1
Hui, H.2
Bertolotto, C.3
Kang, E.4
Bulotta, A.5
Di Mario, U.6
Perfetti, R.7
-
36
-
-
0035167995
-
P2 receptor agonists stimulate insulin release from human pancreatic islets
-
Fernandez-Alvarez J, Hillaire-Buys D, Loubatières-Mariani MM, Gomis R, Petit P. 2001. P2 receptor agonists stimulate insulin release from human pancreatic islets. Pancreas 22:69-71.
-
(2001)
Pancreas
, vol.22
, pp. 69-71
-
-
Fernandez-Alvarez, J.1
Hillaire-Buys, D.2
Loubatières-Mariani, M.M.3
Gomis, R.4
Petit, P.5
-
37
-
-
0030953398
-
Pituitary adenylate cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans
-
Filipsson K, Tornøe K, Holst J, Ahrén B. 1997. Pituitary adenylate cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans. J Clin Endocrinol Metab 82:3093-3098.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 3093-3098
-
-
Filipsson, K.1
Tornøe, K.2
Holst, J.3
Ahrén, B.4
-
38
-
-
0035461315
-
The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function
-
Filipsson K, Kvist-Reimer M, Ahrén B. 2001. The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function. Diabetes 50:1959-1969.
-
(2001)
Diabetes
, vol.50
, pp. 1959-1969
-
-
Filipsson, K.1
Kvist-Reimer, M.2
Ahrén, B.3
-
39
-
-
0037850667
-
Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes
-
Fineman MS, Bicsak TA, Shen LZ, Taylor K, Gaines E, Varns A, Kim D, Baron AD. 2003. Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes. Diabetes Care 26:2370-2377.
-
(2003)
Diabetes Care
, vol.26
, pp. 2370-2377
-
-
Fineman, M.S.1
Bicsak, T.A.2
Shen, L.Z.3
Taylor, K.4
Gaines, E.5
Varns, A.6
Kim, D.7
Baron, A.D.8
-
40
-
-
84918828271
-
Chronic Continuous Exenatide Infusion Does Not Cause Pancreatic Inflammation and Ductal Hyperplasia in Non-Human Primates (baboons; Papio Hamadryas)
-
Fiorentino TV, Owston M, Abrahamian G, La Rosa S, Marando A, Perego C, Di Cairano ES, Finzi G, Capella C, Sessa F, Casiraghi F, Paez A, Adivi A, Davalli A, Fiorina P, Guardado Mendoza R, Comuzzie AG, Sharp M, DeFronzo RA, Halff G, Dick EJ, Folli F. 2015. Chronic Continuous Exenatide Infusion Does Not Cause Pancreatic Inflammation and Ductal Hyperplasia in Non-Human Primates (baboons; Papio Hamadryas). Am J Pathol 185:139-150.
-
(2015)
Am J Pathol
, vol.185
, pp. 139-150
-
-
Fiorentino, T.V.1
Owston, M.2
Abrahamian, G.3
La Rosa, S.4
Marando, A.5
Perego, C.6
Di Cairano, E.S.7
Finzi, G.8
Capella, C.9
Sessa, F.10
Casiraghi, F.11
Paez, A.12
Adivi, A.13
Davalli, A.14
Fiorina, P.15
Guardado Mendoza, R.16
Comuzzie, A.G.17
Sharp, M.18
DeFronzo, R.A.19
Halff, G.20
Dick, E.J.21
Folli, F.22
more..
-
41
-
-
81555228394
-
Potential use of exenatide for the treatment of obesity
-
Folli F, Guardado Mendoza R. 2011. Potential use of exenatide for the treatment of obesity. Expert Opin Investig Drugs. 20:1717-1722.
-
(2011)
Expert Opin Investig Drugs
, vol.20
, pp. 1717-1722
-
-
Folli, F.1
Guardado Mendoza, R.2
-
42
-
-
34548522432
-
The emergence of neurotransmitters as immune modulators
-
Franco R, Pacheco R, Lluis C, Ahern GP, O'Connell PJ. 2007. The emergence of neurotransmitters as immune modulators. Trends Immunol 28:400-407.
-
(2007)
Trends Immunol
, vol.28
, pp. 400-407
-
-
Franco, R.1
Pacheco, R.2
Lluis, C.3
Ahern, G.P.4
O'Connell, P.J.5
-
43
-
-
84867123030
-
Glucagon secretion and signaling in the development of diabetes
-
Gaisano HY, Macdonald PE, Vranic M. 2012. Glucagon secretion and signaling in the development of diabetes. Front Physiol 3:349.
-
(2012)
Front Physiol
, vol.3
, pp. 349
-
-
Gaisano, H.Y.1
Macdonald, P.E.2
Vranic, M.3
-
44
-
-
80051650212
-
A role for glutamate transporters in the regulation of insulin secretion
-
Gammelsaeter R, Coppola T, Marcaggi P, Storm-Mathisen J, Chaudhry FA, Attwell D, Regazzi R, Gundersen V. 2011. A role for glutamate transporters in the regulation of insulin secretion. PLoS ONE 6: e22960.
-
(2011)
PLoS ONE
, vol.6
, pp. e22960
-
-
Gammelsaeter, R.1
Coppola, T.2
Marcaggi, P.3
Storm-Mathisen, J.4
Chaudhry, F.A.5
Attwell, D.6
Regazzi, R.7
Gundersen, V.8
-
45
-
-
84928815070
-
Dopamine modulates insulin release and is involved in the survival of rat pancreatic beta cells
-
Garcia Barrado MJ, Iglesias Osma MC, Blanco EJ, Carretero Hernández M, Sánchez Robledo, V, Catalano Iniesta L, Carrero S, Carretero J. 2015. Dopamine modulates insulin release and is involved in the survival of rat pancreatic beta cells. PLoS ONE 10:e0123197.
-
(2015)
PLoS ONE
, vol.10
, pp. e0123197
-
-
Garcia Barrado, M.J.1
Iglesias Osma, M.C.2
Blanco, E.J.3
Carretero Hernández, M.4
Sánchez Robledo, V.5
Catalano Iniesta, L.6
Carrero, S.7
Carretero, J.8
-
46
-
-
77950265864
-
Disruption of the dopamine D2 receptor impairs insulin secretion and causes glucose intolerance
-
García-Tornadú I, Ornstein AM, Chamson-Reig A, Wheeler MB, Hill DJ, Arany E, Rubinstein M, Becu-Villalobos D. 2010. Disruption of the dopamine D2 receptor impairs insulin secretion and causes glucose intolerance. Endocrinology 151:1441-1450.
-
(2010)
Endocrinology
, vol.151
, pp. 1441-1450
-
-
García-Tornadú, I.1
Ornstein, A.M.2
Chamson-Reig, A.3
Wheeler, M.B.4
Hill, D.J.5
Arany, E.6
Rubinstein, M.7
Becu-Villalobos, D.8
-
47
-
-
35148844231
-
Role of the M3 muscarinic acetylcholine receptor on beta-cell function and glucose homeostasis
-
Gautam D, Han SJ, Duttaroy A, Mears D, Hamdan FF, Li JH, Cui Y, Jeon J, Wess J. 2007. Role of the M3 muscarinic acetylcholine receptor on beta-cell function and glucose homeostasis. Diabetes Obes Metab 9:158-169.
-
(2007)
Diabetes Obes Metab
, vol.9
, pp. 158-169
-
-
Gautam, D.1
Han, S.J.2
Duttaroy, A.3
Mears, D.4
Hamdan, F.F.5
Li, J.H.6
Cui, Y.7
Jeon, J.8
Wess, J.9
-
48
-
-
38049134861
-
Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis
-
Gauthier BR, Duhamel DL, Iezzi M, Theander S, Saltel F, Fukuda M, Wehrle-Haller B, Wollheim CB. 2008. Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis. FASEB J 22:194-206.
-
(2008)
FASEB J
, vol.22
, pp. 194-206
-
-
Gauthier, B.R.1
Duhamel, D.L.2
Iezzi, M.3
Theander, S.4
Saltel, F.5
Fukuda, M.6
Wehrle-Haller, B.7
Wollheim, C.B.8
-
49
-
-
0036311144
-
Molecular determinants of regulated exocytosis
-
Gerber SH, Südhof TC. 2002. Molecular determinants of regulated exocytosis. Diabetes 51:S3-11.
-
(2002)
Diabetes
, vol.51
, pp. S3-11
-
-
Gerber, S.H.1
Südhof, T.C.2
-
50
-
-
84919685379
-
Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion
-
Gheni G, Ogura M, Iwasaki M, Yokoi N, Minami K, Nakayama Y, Harada K, Hastoy B, Wu X, Takahashi H, Kimura K, Matsubara T, Hoshikawa R, Hatano N, Sugawara K, Shibasaki T, Inagaki N, Bamba T, Mizoguchi A, Fukusaki E, Rorsman P, Seino S. 2014. Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion. Cell Rep 9:661-673.
-
(2014)
Cell Rep
, vol.9
, pp. 661-673
-
-
Gheni, G.1
Ogura, M.2
Iwasaki, M.3
Yokoi, N.4
Minami, K.5
Nakayama, Y.6
Harada, K.7
Hastoy, B.8
Wu, X.9
Takahashi, H.10
Kimura, K.11
Matsubara, T.12
Hoshikawa, R.13
Hatano, N.14
Sugawara, K.15
Shibasaki, T.16
Inagaki, N.17
Bamba, T.18
Mizoguchi, A.19
Fukusaki, E.20
Rorsman, P.21
Seino, S.22
more..
-
51
-
-
67650659532
-
Purinergic P2 × 7 receptors regulate secretion of interleukin-1 receptor antagonist and beta cell function and survival
-
Glas R, Sauter NS, Schulthess FT, Shu L, Oberholzer J, Maedler K. 2009. Purinergic P2 × 7 receptors regulate secretion of interleukin-1 receptor antagonist and beta cell function and survival. Diabetologia 52:1579-1588.
-
(2009)
Diabetologia
, vol.52
, pp. 1579-1588
-
-
Glas, R.1
Sauter, N.S.2
Schulthess, F.T.3
Shu, L.4
Oberholzer, J.5
Maedler, K.6
-
52
-
-
34248333311
-
Therapeutical approaches of vasoactive intestinal peptide as a pleiotropic immunomodulator
-
Gonzalez-Rey E, Varela N, Chorny A, Delgado M. 2007. Therapeutical approaches of vasoactive intestinal peptide as a pleiotropic immunomodulator. Curr Pharm Des 13:1113-1139.
-
(2007)
Curr Pharm Des
, vol.13
, pp. 1113-1139
-
-
Gonzalez-Rey, E.1
Varela, N.2
Chorny, A.3
Delgado, M.4
-
53
-
-
84937522765
-
Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas)
-
Guardado Mendoza R, Perego C, Finzi G, La Rosa S, Capella C, Jimenez-Ceja LM, Velloso LA, Saad MJ, Sessa F, Bertuzzi F, Moretti S, Dick EJ, Jr, Davalli AM, Folli F. 2015. Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas). Diabetologia 58:1814-1826.
-
(2015)
Diabetologia
, vol.58
, pp. 1814-1826
-
-
Guardado Mendoza, R.1
Perego, C.2
Finzi, G.3
La Rosa, S.4
Capella, C.5
Jimenez-Ceja, L.M.6
Velloso, L.A.7
Saad, M.J.8
Sessa, F.9
Bertuzzi, F.10
Moretti, S.11
Dick, E.J.12
Davalli, A.M.13
Folli, F.14
-
54
-
-
84904347822
-
Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility
-
Guigas B, de Leeuw van Weenen JE, van Leeuwen N, Simonis-Bik AM, van Haeften TW, Nijpels G, Houwing-Duistermaat JJ, Beekman M, Deelen J, Havekes LM, Penninx BW, Vogelzangs N, van 't Riet E, Dehghan A, Hofman A, Witteman JC, Uitterlinden AG, Grarup N, Jørgensen T, Witte DR, Lauritzen T, Hansen T, Pedersen O, Hottenga J, Romijn JA, Diamant M, Kramer MH, Heine RJ, Willemsen G, Dekker JM, Eekhoff EM, Pijl H, de Geus EJ, Slagboom PE, 't Hart LM. 2014. Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility. Diabet Med 31:1001-1008.
-
(2014)
Diabet Med
, vol.31
, pp. 1001-1008
-
-
Guigas, B.1
de Leeuw van Weenen, J.E.2
van Leeuwen, N.3
Simonis-Bik, A.M.4
van Haeften, T.W.5
Nijpels, G.6
Houwing-Duistermaat, J.J.7
Beekman, M.8
Deelen, J.9
Havekes, L.M.10
Penninx, B.W.11
Vogelzangs, N.12
van 't Riet, E.13
Dehghan, A.14
Hofman, A.15
Witteman, J.C.16
Uitterlinden, A.G.17
Grarup, N.18
Jørgensen, T.19
Witte, D.R.20
Lauritzen, T.21
Hansen, T.22
Pedersen, O.23
Hottenga, J.24
Romijn, J.A.25
Diamant, M.26
Kramer, M.H.27
Heine, R.J.28
Willemsen, G.29
Dekker, J.M.30
Eekhoff, E.M.31
Pijl, H.32
de Geus, E.J.33
Slagboom, P.E.34
't Hart, L.M.35
more..
-
55
-
-
0033982353
-
Pituitary adenylate cyclase-activating polypeptide in intrinsic and extrinsic nerves of the rat pancreas
-
Hannibal J, Fahrenkrug J. 2000. Pituitary adenylate cyclase-activating polypeptide in intrinsic and extrinsic nerves of the rat pancreas. Cell Tissue Res. 299:59-70.
-
(2000)
Cell Tissue Res
, vol.299
, pp. 59-70
-
-
Hannibal, J.1
Fahrenkrug, J.2
-
56
-
-
84912083730
-
Effect of hyperglycaemia on muscarinic M3 receptor expression and secretory sensitivity to cholinergic receptor activation in islets
-
Hauge-Evans AC, Reers C, Kerby A, Franklin Z, Amisten S, King AJ, Hassan Z, Vilches-Flores A, Tippu Z, Persaud SJ, Jones PM. 2014. Effect of hyperglycaemia on muscarinic M3 receptor expression and secretory sensitivity to cholinergic receptor activation in islets. Diabetes Obes Metab 16:947-956.
-
(2014)
Diabetes Obes Metab
, vol.16
, pp. 947-956
-
-
Hauge-Evans, A.C.1
Reers, C.2
Kerby, A.3
Franklin, Z.4
Amisten, S.5
King, A.J.6
Hassan, Z.7
Vilches-Flores, A.8
Tippu, Z.9
Persaud, S.J.10
Jones, P.M.11
-
57
-
-
0037449745
-
Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers glutamatergic signal transmission in islet of Langerhans
-
Hayashi M, Yamada H, Uehara S, Morimoto R, Muroyama A, Yatsushiro S, Takeda J, Yamamoto A, Moriyama Y. 2003a. Secretory granule-mediated co-secretion of L-glutamate and glucagon triggers glutamatergic signal transmission in islet of Langerhans. J Biol Chem 278:1966-1974.
-
(2003)
J Biol Chem
, vol.278
, pp. 1966-1974
-
-
Hayashi, M.1
Yamada, H.2
Uehara, S.3
Morimoto, R.4
Muroyama, A.5
Yatsushiro, S.6
Takeda, J.7
Yamamoto, A.8
Moriyama, Y.9
-
58
-
-
0043268762
-
Vesicular inhibitory amino acid transporter is present in glucagon-containing secretory granules in alphaTC6 cells, mouse clonal alpha-cells, and alpha-cells of islets of Langerhans
-
Hayashi M, Otsuka M, Morimoto R, Muroyama A, Uehara S, Yamamoto A, Moriyama Y. 2003. Vesicular inhibitory amino acid transporter is present in glucagon-containing secretory granules in alphaTC6 cells, mouse clonal alpha-cells, and alpha-cells of islets of Langerhans. Diabetes 52:2066-2074.
-
(2003)
Diabetes
, vol.52
, pp. 2066-2074
-
-
Hayashi, M.1
Otsuka, M.2
Morimoto, R.3
Muroyama, A.4
Uehara, S.5
Yamamoto, A.6
Moriyama, Y.7
-
59
-
-
0030975613
-
Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas
-
Heller RS, Kieffer TJ, Habener JF. 1997. Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas. Diabetes 46:785-791.
-
(1997)
Diabetes
, vol.46
, pp. 785-791
-
-
Heller, R.S.1
Kieffer, T.J.2
Habener, J.F.3
-
60
-
-
0034007213
-
Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets
-
Iismaa TP, Kerr EA, Wilson JR, Carpenter L, Sims N, Biden TJ. 2000. Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets. Diabetes 49:392-398.
-
(2000)
Diabetes
, vol.49
, pp. 392-398
-
-
Iismaa, T.P.1
Kerr, E.A.2
Wilson, J.R.3
Carpenter, L.4
Sims, N.5
Biden, T.J.6
-
61
-
-
36349009725
-
Insulin secretion is increased in pancreatic islets of neuropeptide Y-deficient mice
-
Imai Y, Patel HR, Hawkins EJ, Doliba NM, Matschinsky FM, Ahima RS. 2007. Insulin secretion is increased in pancreatic islets of neuropeptide Y-deficient mice. Endocrinology 148:5716-5723.
-
(2007)
Endocrinology
, vol.148
, pp. 5716-5723
-
-
Imai, Y.1
Patel, H.R.2
Hawkins, E.J.3
Doliba, N.M.4
Matschinsky, F.M.5
Ahima, R.S.6
-
62
-
-
77950885567
-
ATP-gated P2×3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cell
-
Jacques-Silva MC, Correa-Medina M, Cabrera O, Rodriguez-Diaz R, Makeeva N, Fachado A, Diez J, Berman DM, Kenyon NS, Ricordi C, Pileggi A, Molano RD, Berggren PO, Caicedo A. 2010. ATP-gated P2×3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cell. Proc Natl Acad Sci USA 107:6465-6470.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6465-6470
-
-
Jacques-Silva, M.C.1
Correa-Medina, M.2
Cabrera, O.3
Rodriguez-Diaz, R.4
Makeeva, N.5
Fachado, A.6
Diez, J.7
Berman, D.M.8
Kenyon, N.S.9
Ricordi, C.10
Pileggi, A.11
Molano, R.D.12
Berggren, P.O.13
Caicedo, A.14
-
63
-
-
0025719222
-
Peptide contents of neuropeptide Y, vasoactive intestinal polypeptide, and beta-calcitonin gene-related peptide and their messenger ribonucleic acids after dexamethasone treatment in the isolated rat islets of Langerhans
-
Jamal H, Jones PM, Byrne J, Suda K, Ghatei MA, Kanse SM, Bloom SR. 1991. Peptide contents of neuropeptide Y, vasoactive intestinal polypeptide, and beta-calcitonin gene-related peptide and their messenger ribonucleic acids after dexamethasone treatment in the isolated rat islets of Langerhans. Endocrinology 129:3372-3380.
-
(1991)
Endocrinology
, vol.129
, pp. 3372-3380
-
-
Jamal, H.1
Jones, P.M.2
Byrne, J.3
Suda, K.4
Ghatei, M.A.5
Kanse, S.M.6
Bloom, S.R.7
-
64
-
-
79952192382
-
Immune cell regulation by autocrine purinergic signalling
-
Junger WG. 2011. Immune cell regulation by autocrine purinergic signalling. Nat Rev Immunol 11:201-212.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 201-212
-
-
Junger, W.G.1
-
65
-
-
77953438340
-
Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic α-cells in mouse models of ß-cell regeneration
-
Kilimnik G, Kim A, Steiner DF, Friedman TC, Hara M. 2010. Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic α-cells in mouse models of ß-cell regeneration. Islets 2:149-155.
-
(2010)
Islets
, vol.2
, pp. 149-155
-
-
Kilimnik, G.1
Kim, A.2
Steiner, D.F.3
Friedman, T.C.4
Hara, M.5
-
66
-
-
84868196557
-
Paracrine interactions within islets of Langerhans
-
Koh DS, Cho JH, Chen L. 2012. Paracrine interactions within islets of Langerhans. J Mol Neurosci 48:429-440.
-
(2012)
J Mol Neurosci
, vol.48
, pp. 429-440
-
-
Koh, D.S.1
Cho, J.H.2
Chen, L.3
-
67
-
-
0030590483
-
Structural diversity of receptors for neuropeptides Y, peptide YY and pancreatic polypeptide
-
Larhammar D. 1996. Structural diversity of receptors for neuropeptides Y, peptide YY and pancreatic polypeptide. Regul Pept 65:165-174.
-
(1996)
Regul Pept
, vol.65
, pp. 165-174
-
-
Larhammar, D.1
-
68
-
-
33847686231
-
Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid
-
Ligon B, Yang J, Morin SB, Ruberti MF, Steer ML. 2007. Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid. Diabetologia 50:764-773.
-
(2007)
Diabetologia
, vol.50
, pp. 764-773
-
-
Ligon, B.1
Yang, J.2
Morin, S.B.3
Ruberti, M.F.4
Steer, M.L.5
-
69
-
-
0022979983
-
Aromatic-L-amino-acid decarboxylase activity in mouse pancreatic islets
-
Lindström P. 1986. Aromatic-L-amino-acid decarboxylase activity in mouse pancreatic islets. Biochim Biophys Acta 884:276-281.
-
(1986)
Biochim Biophys Acta
, vol.884
, pp. 276-281
-
-
Lindström, P.1
-
70
-
-
0020026919
-
Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem
-
Lund PK, Goodman RH, Dee PC, Habener JF. 1982. Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem. Proc Natl Acad Sci USA 79:345-349.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 345-349
-
-
Lund, P.K.1
Goodman, R.H.2
Dee, P.C.3
Habener, J.F.4
-
71
-
-
0025883235
-
Effect of L-dopa administration on islet monoamine oxidase activity and glucose-induced insulin release in the mouse
-
Lundquist I, Panagiotidis G, Stenstrom A. 1991. Effect of L-dopa administration on islet monoamine oxidase activity and glucose-induced insulin release in the mouse. Pancreas 6:522-527.
-
(1991)
Pancreas
, vol.6
, pp. 522-527
-
-
Lundquist, I.1
Panagiotidis, G.2
Stenstrom, A.3
-
72
-
-
53749089676
-
Crosstalk of vascular 5-HT1 receptors with other receptors: Clinical implications
-
Maassen VanDenBrink A, Centurión D, Villalón CM. 2008. Crosstalk of vascular 5-HT1 receptors with other receptors: Clinical implications. Neuropharmacology 55:986-993.
-
(2008)
Neuropharmacology
, vol.55
, pp. 986-993
-
-
Maassen VanDenBrink, A.1
Centurión, D.2
Villalón, C.M.3
-
73
-
-
33748946239
-
Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β cells
-
MacDonald P, Braun M, Galvanovskis J, Rorsman P. 2006. Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β cells. Cell Metabolism 4:283-290.
-
(2006)
Cell Metabolism
, vol.4
, pp. 283-290
-
-
MacDonald, P.1
Braun, M.2
Galvanovskis, J.3
Rorsman, P.4
-
74
-
-
34250307235
-
A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans
-
MacDonald PE, De Marinis YZ, Ramracheya R, Salehi A, Ma X, Johnson PR, Cox R, Eliasson L, Rorsman P. 2007. A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans. PLoS Biol 5:e143.
-
(2007)
PLoS Biol
, vol.5
, pp. e143
-
-
MacDonald, P.E.1
De Marinis, Y.Z.2
Ramracheya, R.3
Salehi, A.4
Ma, X.5
Johnson, P.R.6
Cox, R.7
Eliasson, L.8
Rorsman, P.9
-
75
-
-
0033540037
-
Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis
-
Maechler P, Wollheim CB. 1999. Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis. Nature 402:685-689.
-
(1999)
Nature
, vol.402
, pp. 685-689
-
-
Maechler, P.1
Wollheim, C.B.2
-
76
-
-
84926685729
-
Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment
-
Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen MS, Stožer A, Wnendt S, Piemonti L, Köhler M, Ferrer J, Thorens B, Schliess F, Rupnik MS, Heise T, Berggren PO, Klöcker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E. 2015. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment. Nat Med 21:363-372.
-
(2015)
Nat Med
, vol.21
, pp. 363-372
-
-
Marquard, J.1
Otter, S.2
Welters, A.3
Stirban, A.4
Fischer, A.5
Eglinger, J.6
Herebian, D.7
Kletke, O.8
Klemen, M.S.9
Stožer, A.10
Wnendt, S.11
Piemonti, L.12
Köhler, M.13
Ferrer, J.14
Thorens, B.15
Schliess, F.16
Rupnik, M.S.17
Heise, T.18
Berggren, P.O.19
Klöcker, N.20
Meissner, T.21
Mayatepek, E.22
Eberhard, D.23
Kragl, M.24
Lammert, E.25
more..
-
77
-
-
0028349215
-
Processing and metabolism of peptide-YY: Pivotal roles of dipeptidylpeptidase-IV, aminopeptidase-P, and endopeptidase-24. 11
-
Medeiros MD, Turner AJ. 1994. Processing and metabolism of peptide-YY: Pivotal roles of dipeptidylpeptidase-IV, aminopeptidase-P, and endopeptidase-24. 11. Endocrinology 134:2088-2094.
-
(1994)
Endocrinology
, vol.134
, pp. 2088-2094
-
-
Medeiros, M.D.1
Turner, A.J.2
-
78
-
-
0029813426
-
A novel non neuronal catecholaminergic system: Exocrine pancreas synthesizes and releases dopamine
-
Mezey E, Eisenhofer G, Harta G, Hansson S, Gould L, Hunyady B, Hoffman BJ. 1996. A novel non neuronal catecholaminergic system: Exocrine pancreas synthesizes and releases dopamine. Proc Natl Acad Sci USA 93:10377-10382.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10377-10382
-
-
Mezey, E.1
Eisenhofer, G.2
Harta, G.3
Hansson, S.4
Gould, L.5
Hunyady, B.6
Hoffman, B.J.7
-
79
-
-
0024498654
-
Metabolite-regulated ATP-sensitive K+ channel in human pancreatic islet cells
-
Misler S, Gee WM, Gillis KD, Scharp DW, Falke LC. 1989. Metabolite-regulated ATP-sensitive K+ channel in human pancreatic islet cells. Diabetes 38:422-427.
-
(1989)
Diabetes
, vol.38
, pp. 422-427
-
-
Misler, S.1
Gee, W.M.2
Gillis, K.D.3
Scharp, D.W.4
Falke, L.C.5
-
80
-
-
13344293675
-
Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells
-
Moens K, Heimberg H, Flamez D, Huypens P, Quartier E, Ling Z, Pipeleers D, Gremlich S, Thorens B, Schuit F. 1996. Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. Diabetes 45:257-261.
-
(1996)
Diabetes
, vol.45
, pp. 257-261
-
-
Moens, K.1
Heimberg, H.2
Flamez, D.3
Huypens, P.4
Quartier, E.5
Ling, Z.6
Pipeleers, D.7
Gremlich, S.8
Thorens, B.9
Schuit, F.10
-
81
-
-
84905040917
-
Control of insulin secretion by cholinergic signaling in the human pancreatic islet
-
Molina J, Rodriguez-Diaz R, Fachado A, Jacques-Silva MC, Berggren PO, Caicedo A. 2014. Control of insulin secretion by cholinergic signaling in the human pancreatic islet. Diabetes 63:2714-2726.
-
(2014)
Diabetes
, vol.63
, pp. 2714-2726
-
-
Molina, J.1
Rodriguez-Diaz, R.2
Fachado, A.3
Jacques-Silva, M.C.4
Berggren, P.O.5
Caicedo, A.6
-
82
-
-
0031797940
-
Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenyl cyclase in RIN 5AH rat insulinoma cells
-
Morgan DG, Kulkarni RN, Hurley JD, Wang ZL, Wang RM, Ghatei MA, Karlsen AE, Bloom SR, Smith DM. 1998. Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenyl cyclase in RIN 5AH rat insulinoma cells. Diabetologia 41:1482-1491.
-
(1998)
Diabetologia
, vol.41
, pp. 1482-1491
-
-
Morgan, D.G.1
Kulkarni, R.N.2
Hurley, J.D.3
Wang, Z.L.4
Wang, R.M.5
Ghatei, M.A.6
Karlsen, A.E.7
Bloom, S.R.8
Smith, D.M.9
-
83
-
-
0141987898
-
Glutamate-mediated signaling in the islets of Langerhans: a thread entangled
-
Moriyama Y, Hayashi M. 2003. Glutamate-mediated signaling in the islets of Langerhans: a thread entangled. Trends Pharmacol Sci 24:511-517.
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 511-517
-
-
Moriyama, Y.1
Hayashi, M.2
-
84
-
-
3042739361
-
A novel variant of ionotropic glutamate receptor regulates somatostatin secretion from delta-cells of islets of Langerhans
-
Muroyama A, Uehara S, Yatsushiro S, Echigo N, Morimoto R, Morita M, Hayashi M, Yamamoto A, Koh DS, Moriyama Y. 2004. A novel variant of ionotropic glutamate receptor regulates somatostatin secretion from delta-cells of islets of Langerhans. Diabetes 53:1743-1753.
-
(2004)
Diabetes
, vol.53
, pp. 1743-1753
-
-
Muroyama, A.1
Uehara, S.2
Yatsushiro, S.3
Echigo, N.4
Morimoto, R.5
Morita, M.6
Hayashi, M.7
Yamamoto, A.8
Koh, D.S.9
Moriyama, Y.10
-
85
-
-
0028845585
-
Neuropeptide Y is expressed in subpopulations of insulin- and non-insulin-producing islet cells in the rat after dexamethasone treatment: A combined immunocytochemical and in situ hybridisation study
-
Myrsén U, Ahrén B, Sundler F. 1995. Neuropeptide Y is expressed in subpopulations of insulin- and non-insulin-producing islet cells in the rat after dexamethasone treatment: A combined immunocytochemical and in situ hybridisation study. Regul Pept 60:19-31.
-
(1995)
Regul Pept
, vol.60
, pp. 19-31
-
-
Myrsén, U.1
Ahrén, B.2
Sundler, F.3
-
86
-
-
78349310241
-
Intra-islet PACAP protects pancreatic β-cells against glucotoxicity and lipotoxicity
-
Nakata M, Shintani N, Hashimoto H, Baba A, Yada T. 2010. Intra-islet PACAP protects pancreatic β-cells against glucotoxicity and lipotoxicity. J Mol Neurosci 42:404-410.
-
(2010)
J Mol Neurosci
, vol.42
, pp. 404-410
-
-
Nakata, M.1
Shintani, N.2
Hashimoto, H.3
Baba, A.4
Yada, T.5
-
87
-
-
84927948227
-
Regulation of systemic energy homeostasis by serotonin in adipose tissues
-
Oh CM, Namkung J, Go Y, Shong KE, Kim K, Kim H, Park BY, Lee HW, Jeon YH, Song J, Shong M, Yadav VK, Karsenty G, Kajimura S, Lee IK, Park S, Kim H. 2015. Regulation of systemic energy homeostasis by serotonin in adipose tissues. Nat Commun 6:6794.
-
(2015)
Nat Commun
, vol.6
, pp. 6794
-
-
Oh, C.M.1
Namkung, J.2
Go, Y.3
Shong, K.E.4
Kim, K.5
Kim, H.6
Park, B.Y.7
Lee, H.W.8
Jeon, Y.H.9
Song, J.10
Shong, M.11
Yadav, V.K.12
Karsenty, G.13
Kajimura, S.14
Lee, I.K.15
Park, S.16
Kim, H.17
-
88
-
-
82255185857
-
Convergence of the Insulin and Serotonin Programs in the Pancreatic β-Cell
-
Ohta Y, Kosaka Y, Kishimoto N, Wang J, Smith SB, Honig G, Kim H, Gasa RM, Neubauer N, Liou A, Tecott LH, Deneris ES, German MS. 2011. Convergence of the Insulin and Serotonin Programs in the Pancreatic β-Cell. Diabetes 60:3208-3216.
-
(2011)
Diabetes
, vol.60
, pp. 3208-3216
-
-
Ohta, Y.1
Kosaka, Y.2
Kishimoto, N.3
Wang, J.4
Smith, S.B.5
Honig, G.6
Kim, H.7
Gasa, R.M.8
Neubauer, N.9
Liou, A.10
Tecott, L.H.11
Deneris, E.S.12
German, M.S.13
-
89
-
-
0016801222
-
Cell contacts in human islets of Langerhans
-
Orci L, Malaisse-Lagae F, Amherdt M, Ravazzola M, Weisswange A, Dobbs R, Perrelet A, Unger R. 1975. Cell contacts in human islets of Langerhans. J Clin Endocrinol Metab 41:841-844.
-
(1975)
J Clin Endocrinol Metab
, vol.41
, pp. 841-844
-
-
Orci, L.1
Malaisse-Lagae, F.2
Amherdt, M.3
Ravazzola, M.4
Weisswange, A.5
Dobbs, R.6
Perrelet, A.7
Unger, R.8
-
90
-
-
70350520200
-
Intracellular serotonin modulates insulin secretion from pancreatic š-cells by protein serotonylation
-
Paulmann N, Grohmann M, Voigt J-P, Bert B, Vowinckel J, Bader M, Skelin M, Jevšek M, Fink H, Rupnik M, Walther DJ. 2009. Intracellular serotonin modulates insulin secretion from pancreatic š-cells by protein serotonylation. PLoS Biol 7:e1000229.
-
(2009)
PLoS Biol
, vol.7
, pp. e1000229
-
-
Paulmann, N.1
Grohmann, M.2
Voigt, J.-P.3
Bert, B.4
Vowinckel, J.5
Bader, M.6
Skelin, M.7
Jevšek, M.8
Fink, H.9
Rupnik, M.10
Walther, D.J.11
-
91
-
-
84961880908
-
Modulation of glutamate signalling in human islets of Langerhans under hyperglycaemia
-
Perego C, Moretti S, Di Cairano ES, Daniele F, La Rosa S, Bertuzzi F, Davalli A, Folli F. 2014. Modulation of glutamate signalling in human islets of Langerhans under hyperglycaemia. Diabetologia 57:S194.
-
(2014)
Diabetologia
, vol.57
, pp. S194
-
-
Perego, C.1
Moretti, S.2
Di Cairano, E.S.3
Daniele, F.4
La Rosa, S.5
Bertuzzi, F.6
Davalli, A.7
Folli, F.8
-
92
-
-
0036721026
-
Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4
-
Perry T, Haughey NJ, Mattson MP, Egan JM, Greig NH. 2002. Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4. J Pharmacol Exp Ther 302:881-888.
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 881-888
-
-
Perry, T.1
Haughey, N.J.2
Mattson, M.P.3
Egan, J.M.4
Greig, N.H.5
-
93
-
-
62649114002
-
P2 purinergic signaling in the pancreatic beta-cell: control of insulin secretion and pharmacology
-
Petit P, Lajoix AD, Gross R. 2009. P2 purinergic signaling in the pancreatic beta-cell: control of insulin secretion and pharmacology. Eur J Pharm Sci 37:67-75.
-
(2009)
Eur J Pharm Sci
, vol.37
, pp. 67-75
-
-
Petit, P.1
Lajoix, A.D.2
Gross, R.3
-
94
-
-
84936166069
-
A randomized, controlled trial of 3.0 mg of liraglutide in weight management
-
SCALE Obesity and Prediabetes NN8022-1839 Study Group
-
Pi-Sunyer X, Astrup A, Fujioka K, Greenway F, Halpern A, Krempf M, Lau DC, le Roux CW, Violante Ortiz R, Jensen CB, Wilding JP, SCALE Obesity and Prediabetes NN8022-1839 Study Group. 2015. A randomized, controlled trial of 3.0 mg of liraglutide in weight management. N Engl J Med 373:11-22.
-
(2015)
N Engl J Med
, vol.373
, pp. 11-22
-
-
Pi-Sunyer, X.1
Astrup, A.2
Fujioka, K.3
Greenway, F.4
Halpern, A.5
Krempf, M.6
Lau, D.C.7
le Roux, C.W.8
Violante Ortiz, R.9
Jensen, C.B.10
Wilding, J.P.11
-
95
-
-
0037447728
-
PACAP is expressed in secretory granules of insulin and glucagon cells in human and rodent pancreas. Evidence for generation of cAMP compartments uncoupled from hormone release in diabetic islets
-
Portela-Gomes GM, Lukinius A, Ljungberg O, Efendic S, Ahrén B, Abdel-Halim SM. 2003. PACAP is expressed in secretory granules of insulin and glucagon cells in human and rodent pancreas. Evidence for generation of cAMP compartments uncoupled from hormone release in diabetic islets. Regul Pept 113:31-39.
-
(2003)
Regul Pept
, vol.113
, pp. 31-39
-
-
Portela-Gomes, G.M.1
Lukinius, A.2
Ljungberg, O.3
Efendic, S.4
Ahrén, B.5
Abdel-Halim, S.M.6
-
96
-
-
47849122048
-
Role of vesicular monoamine transporter type 2 in rodent insulin secretion and glucose metabolism revealed by its specific antagonist tetrabenazine
-
Raffo A, Hancock K, Polito T, Xie Y, Andan G, Witkowski P, Hardy M, Barba P, Ferrara C, Maffei A, Freeby M, Goland R, Leibel RL, Sweet IR, Harris PE. 2008. Role of vesicular monoamine transporter type 2 in rodent insulin secretion and glucose metabolism revealed by its specific antagonist tetrabenazine. J Endocrinol 198:41-49.
-
(2008)
J Endocrinol
, vol.198
, pp. 41-49
-
-
Raffo, A.1
Hancock, K.2
Polito, T.3
Xie, Y.4
Andan, G.5
Witkowski, P.6
Hardy, M.7
Barba, P.8
Ferrara, C.9
Maffei, A.10
Freeby, M.11
Goland, R.12
Leibel, R.L.13
Sweet, I.R.14
Harris, P.E.15
-
97
-
-
0025875235
-
GABA and pancreatic beta-cells: Colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion
-
Reetz A, Solimena M, Matteoli M, Folli F, Takei K, De Camilli P. 1991. GABA and pancreatic beta-cells: Colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion. EMBO J 10:1275-1284.
-
(1991)
EMBO J
, vol.10
, pp. 1275-1284
-
-
Reetz, A.1
Solimena, M.2
Matteoli, M.3
Folli, F.4
Takei, K.5
De Camilli, P.6
-
98
-
-
79959987811
-
Innervation patterns of autonomic axons in the human endocrine pancreas
-
Rodriguez-Diaz R, Abdulreda MH, Formoso AL, Gans I, Ricordi C, Berggren PO, Caicedo A. 2011a. Innervation patterns of autonomic axons in the human endocrine pancreas. Cell Metab 14:45-54.
-
(2011)
Cell Metab
, vol.14
, pp. 45-54
-
-
Rodriguez-Diaz, R.1
Abdulreda, M.H.2
Formoso, A.L.3
Gans, I.4
Ricordi, C.5
Berggren, P.O.6
Caicedo, A.7
-
99
-
-
79960129197
-
Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans
-
Rodriguez-Diaz R, Dando R, Jacques-Silva MC, Fachado A, Molina J, Abdulreda MH, Ricordi C, Roper SD, Berggren PO, Caicedo A. 2011b. Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans. Nat Med 17:888-892.
-
(2011)
Nat Med
, vol.17
, pp. 888-892
-
-
Rodriguez-Diaz, R.1
Dando, R.2
Jacques-Silva, M.C.3
Fachado, A.4
Molina, J.5
Abdulreda, M.H.6
Ricordi, C.7
Roper, S.D.8
Berggren, P.O.9
Caicedo, A.10
-
101
-
-
34250741677
-
Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection
-
Romera C, Hurtado O, Mallolas J, Pereira MP, Morales JR, Romera A, Serena J, Vivancos J, Nombela F, Lorenzo P, Lizasoain I, Moro MA. 2007. Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection. J Cereb Blood Flow Metab 27:1327-1338.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 1327-1338
-
-
Romera, C.1
Hurtado, O.2
Mallolas, J.3
Pereira, M.P.4
Morales, J.R.5
Romera, A.6
Serena, J.7
Vivancos, J.8
Nombela, F.9
Lorenzo, P.10
Lizasoain, I.11
Moro, M.A.12
-
102
-
-
0024470349
-
Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels
-
Rorsman P, Berggren PO, Bokvist K, Ericson H, Möhler H, Ostenson CG, Smith PA. 1989. Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels. Nature 341:233-236.
-
(1989)
Nature
, vol.341
, pp. 233-236
-
-
Rorsman, P.1
Berggren, P.O.2
Bokvist, K.3
Ericson, H.4
Möhler, H.5
Ostenson, C.G.6
Smith, P.A.7
-
103
-
-
84873670723
-
Regulation of insulin secretion in human pancreatic islets
-
Rorsman P, Braun M. 2013. Regulation of insulin secretion in human pancreatic islets. Annu Rev Physiol 75:155-179.
-
(2013)
Annu Rev Physiol
, vol.75
, pp. 155-179
-
-
Rorsman, P.1
Braun, M.2
-
104
-
-
34249899669
-
A randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of topiramate controlled release in the treatment of obese type 2 diabetic patients
-
OBD-202 Study Group
-
Rosenstock J, Hollander P, Gadde KM, Sun X, Strauss R, Leung A, OBD-202 Study Group. 2007. A randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of topiramate controlled release in the treatment of obese type 2 diabetic patients. Diabetes Care 30:1480-1486.
-
(2007)
Diabetes Care
, vol.30
, pp. 1480-1486
-
-
Rosenstock, J.1
Hollander, P.2
Gadde, K.M.3
Sun, X.4
Strauss, R.5
Leung, A.6
-
105
-
-
27744588806
-
Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion
-
Rubì B, Ljubicic S, Pournourmohammadi S, Carobbio S, Armanet M, Bartley C, Maechler P. 2005. Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion. J Biol Chem 280:36824-36832.
-
(2005)
J Biol Chem
, vol.280
, pp. 36824-36832
-
-
Rubì, B.1
Ljubicic, S.2
Pournourmohammadi, S.3
Carobbio, S.4
Armanet, M.5
Bartley, C.6
Maechler, P.7
-
106
-
-
33744492048
-
Insulin vesicle release: walk, kiss, pause then run
-
Rutter GA, Hill EV. 2006. Insulin vesicle release: walk, kiss, pause then run. Physiology 21:189-196.
-
(2006)
Physiology
, vol.21
, pp. 189-196
-
-
Rutter, G.A.1
Hill, E.V.2
-
107
-
-
79951576817
-
Trophic effects of PACAP on pancreatic islets: a mini-review
-
Sakurai Y, Shintani N, Hayata A, Hashimoto H, Baba A. 2011. Trophic effects of PACAP on pancreatic islets: a mini-review. J Mol Neurosci 43:3-7.
-
(2011)
J Mol Neurosci
, vol.43
, pp. 3-7
-
-
Sakurai, Y.1
Shintani, N.2
Hayata, A.3
Hashimoto, H.4
Baba, A.5
-
108
-
-
84864241584
-
Selective ablation of peptide YY cells in adult mice reveals their role in beta cell survival
-
Sam AH, Gunner DJ, King A, Persaud SJ, Brooks L, Hostomska K, Ford HE, Liu B, Ghatei MA, Bloom SR, Bewick GA. 2012. Selective ablation of peptide YY cells in adult mice reveals their role in beta cell survival. Gastroenterology 143:459-468.
-
(2012)
Gastroenterology
, vol.143
, pp. 459-468
-
-
Sam, A.H.1
Gunner, D.J.2
King, A.3
Persaud, S.J.4
Brooks, L.5
Hostomska, K.6
Ford, H.E.7
Liu, B.8
Ghatei, M.A.9
Bloom, S.R.10
Bewick, G.A.11
-
109
-
-
84867917463
-
Therapeutic potential of VIP vs PACAP in diabetes.J
-
Sanlioglu AD, Karacay B, Balci MK, Griffith TS, Sanlioglu S. 2012. Therapeutic potential of VIP vs PACAP in diabetes.J. Mol Endocrinol. 49:R157-R167.
-
(2012)
Mol Endocrinol.
, vol.49
, pp. R157-R167
-
-
Sanlioglu, A.D.1
Karacay, B.2
Balci, M.K.3
Griffith, T.S.4
Sanlioglu, S.5
-
110
-
-
84883765959
-
Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus
-
SAVOR-TIMI 53 Steering Committee and Investigators
-
Scirica BM, Bhatt DL, Braunwald E, Steg PG, Davidson J, Hirshberg B, Ohman P, Frederich R, Wiviott SD, Hoffman EB, Cavender MA, Udell JA, Desai NR, Mosenzon O, McGuire DK, Ray KK, Leiter LA, Raz I. SAVOR-TIMI 53 Steering Committee and Investigators. 2013. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med 369:1317-1326.
-
(2013)
N Engl J Med
, vol.369
, pp. 1317-1326
-
-
Scirica, B.M.1
Bhatt, D.L.2
Braunwald, E.3
Steg, P.G.4
Davidson, J.5
Hirshberg, B.6
Ohman, P.7
Frederich, R.8
Wiviott, S.D.9
Hoffman, E.B.10
Cavender, M.A.11
Udell, J.A.12
Desai, N.R.13
Mosenzon, O.14
McGuire, D.K.15
Ray, K.K.16
Leiter, L.A.17
Raz, I.18
-
111
-
-
0031922709
-
Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling
-
Scrocchi LA, Marshall BA, Cook SM, Brubaker PL, Drucker DJ. 1998. Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling. Diabetes 47:632-639.
-
(1998)
Diabetes
, vol.47
, pp. 632-639
-
-
Scrocchi, L.A.1
Marshall, B.A.2
Cook, S.M.3
Brubaker, P.L.4
Drucker, D.J.5
-
112
-
-
33646857967
-
Dopaminergic regulation of glucose-induced insulin secretion through dopamine D2 receptors in the pancreatic islets in vitro
-
Shankar E, Santhosh KT, Paulose CS. 2006. Dopaminergic regulation of glucose-induced insulin secretion through dopamine D2 receptors in the pancreatic islets in vitro. IUBMB Life. 58:157-163.
-
(2006)
IUBMB Life.
, vol.58
, pp. 157-163
-
-
Shankar, E.1
Santhosh, K.T.2
Paulose, C.S.3
-
113
-
-
0242332771
-
Functional roles of the neuropeptide PACAP in brain and pancreas
-
Shintani N, Tomimoto S, Hashimoto H, Kawaguchi C, Baba A. 2003. Functional roles of the neuropeptide PACAP in brain and pancreas. Life Sci 74:337-343.
-
(2003)
Life Sci
, vol.74
, pp. 337-343
-
-
Shintani, N.1
Tomimoto, S.2
Hashimoto, H.3
Kawaguchi, C.4
Baba, A.5
-
114
-
-
84867017568
-
Dopamine-mediated autocrine inhibitory circuit regulating human insulin secretion in vitro
-
Simpson N, Maffei A, Freeby M, Burroughs S, Freyberg Z, Javitch J, Leibel RL, Harris PE. 2012. Dopamine-mediated autocrine inhibitory circuit regulating human insulin secretion in vitro. Mol Endocrinol 26:1757-1772.
-
(2012)
Mol Endocrinol
, vol.26
, pp. 1757-1772
-
-
Simpson, N.1
Maffei, A.2
Freeby, M.3
Burroughs, S.4
Freyberg, Z.5
Javitch, J.6
Leibel, R.L.7
Harris, P.E.8
-
115
-
-
0035313223
-
Glutamate signaling in non-neuronal tissues
-
Skerry TM, Genever PG. 2001. Glutamate signaling in non-neuronal tissues. Trends Pharmacol Sci 22:174-181.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 174-181
-
-
Skerry, T.M.1
Genever, P.G.2
-
116
-
-
79960996764
-
GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes
-
Soltani N, Qiu H, Aleksic M, Glinka Y, Zhao F, Liu R, Li Y, Zhang N, Chakrabarti R, Ng T, Jin T, Zhang H, Lu WY, Feng ZP, Prud'homme GJ, Wang Q. 2011. GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes. Proc Natl Acad Sci USA 108:11692-11697.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 11692-11697
-
-
Soltani, N.1
Qiu, H.2
Aleksic, M.3
Glinka, Y.4
Zhao, F.5
Liu, R.6
Li, Y.7
Zhang, N.8
Chakrabarti, R.9
Ng, T.10
Jin, T.11
Zhang, H.12
Lu, W.Y.13
Feng, Z.P.14
Prud'homme, G.J.15
Wang, Q.16
-
117
-
-
77955551862
-
Voltage-dependent K(+) channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans
-
Spigelman AF, Dai X, MacDonald PE. 2010. Voltage-dependent K(+) channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans. Diabetologia 53:1917-1926.
-
(2010)
Diabetologia
, vol.53
, pp. 1917-1926
-
-
Spigelman, A.F.1
Dai, X.2
MacDonald, P.E.3
-
118
-
-
0026505528
-
The vascular order of islet cellular perfusion in the human pancreas
-
Stagner JI, Samols E. 1992. The vascular order of islet cellular perfusion in the human pancreas. Diabetes 41:93-97.
-
(1992)
Diabetes
, vol.41
, pp. 93-97
-
-
Stagner, J.I.1
Samols, E.2
-
119
-
-
79960262492
-
Management of type 2 diabetes: new and future developments in treatment
-
Tahrani AA, Bailey CJ, Del Prato S, Barnett AH. 2011. Management of type 2 diabetes: new and future developments in treatment. Lancet 378:182-197.
-
(2011)
Lancet
, vol.378
, pp. 182-197
-
-
Tahrani, A.A.1
Bailey, C.J.2
Del Prato, S.3
Barnett, A.H.4
-
120
-
-
0019944850
-
Neuropeptide Y a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide
-
Tatemoto K, Carlquist M, Mutt V. 1982. Neuropeptide Y a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide. Nature 296:659-660.
-
(1982)
Nature
, vol.296
, pp. 659-660
-
-
Tatemoto, K.1
Carlquist, M.2
Mutt, V.3
-
121
-
-
0027265223
-
A gamma-aminobutyric acid transporter driven by a proton pump is present in synaptic-like microvesicles of pancreatic beta cells
-
Thomas-Reetz A, Hell JW, During MJ, Walch-Solimena C, Jahn R, De Camilli P. 1993. A gamma-aminobutyric acid transporter driven by a proton pump is present in synaptic-like microvesicles of pancreatic beta cells. Proc Natl Acad Sci USA 90:5317-5321.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 5317-5321
-
-
Thomas-Reetz, A.1
Hell, J.W.2
During, M.J.3
Walch-Solimena, C.4
Jahn, R.5
De Camilli, P.6
-
122
-
-
80053078763
-
Oral treatment with gamma-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice
-
Tian J, Dang HN, Yong J, Kaufman DL. 2011. Oral treatment with gamma-aminobutyric acid improves glucose tolerance and insulin sensitivity by inhibiting inflammation in high fat diet-fed mice. PLoS ONE 6:e25338.
-
(2011)
PLoS ONE
, vol.6
, pp. e25338
-
-
Tian, J.1
Dang, H.N.2
Yong, J.3
Kaufman, D.L.4
-
123
-
-
84891715964
-
γ-Aminobutyric acid regulates both the survival and replication of human β-cells
-
Tian J, Dang H, Chen Z, Guan A, Jin Y, Atkinson MA, Kaufman DL. 2013. γ-Aminobutyric acid regulates both the survival and replication of human β-cells. Diabetes 62:3760-3765.
-
(2013)
Diabetes
, vol.62
, pp. 3760-3765
-
-
Tian, J.1
Dang, H.2
Chen, Z.3
Guan, A.4
Jin, Y.5
Atkinson, M.A.6
Kaufman, D.L.7
-
124
-
-
49749113817
-
Expression of the GLP-1 receptor in mouse, rat, and human pancreas
-
Tornehave D, Kristensen P, Rømer J, Knudsen LB, Heller RS. 2008. Expression of the GLP-1 receptor in mouse, rat, and human pancreas. J Histochem Cytochem 56:841-851.
-
(2008)
J Histochem Cytochem
, vol.56
, pp. 841-851
-
-
Tornehave, D.1
Kristensen, P.2
Rømer, J.3
Knudsen, L.B.4
Heller, R.S.5
-
125
-
-
0036312399
-
A potent and highly selective VPAC2 agonist enhances glucose-induced insulin release and glucose disposal: a potential therapy for type 2 diabetes
-
Tsutsumi M, Claus TH, Liang Y, Li Y, Yang L, Zhu J, Dela Cruz F, Peng X, Chen H, Yung SL, Hamren S, Livingston JN, Pan CQ. 2002. A potent and highly selective VPAC2 agonist enhances glucose-induced insulin release and glucose disposal: a potential therapy for type 2 diabetes. Diabetes 51:1453-1460.
-
(2002)
Diabetes
, vol.51
, pp. 1453-1460
-
-
Tsutsumi, M.1
Claus, T.H.2
Liang, Y.3
Li, Y.4
Yang, L.5
Zhu, J.6
Dela Cruz, F.7
Peng, X.8
Chen, H.9
Yung, S.L.10
Hamren, S.11
Livingston, J.N.12
Pan, C.Q.13
-
126
-
-
1842423000
-
Metabotropic glutamate receptor type 4 is involved in autoinhibitory cascade for glucagon secretion by alpha-cells of islet of Langerhans
-
Uehara S, Muroyama A, Echigo N, Morimoto R, Otsuka M, Yatsushiro S, Moriyama Y. 2004. Metabotropic glutamate receptor type 4 is involved in autoinhibitory cascade for glucagon secretion by alpha-cells of islet of Langerhans. Diabetes 53:998-1006.
-
(2004)
Diabetes
, vol.53
, pp. 998-1006
-
-
Uehara, S.1
Muroyama, A.2
Echigo, N.3
Morimoto, R.4
Otsuka, M.5
Yatsushiro, S.6
Moriyama, Y.7
-
127
-
-
84868129185
-
Dopamine synthesis and D3 receptor activation in pancreatic β-cells regulates insulin secretion and intracellular [Ca(2+)] oscillations
-
Ustione A, Piston DW. 2012. Dopamine synthesis and D3 receptor activation in pancreatic β-cells regulates insulin secretion and intracellular [Ca(2+)] oscillations. Mol Endocrinol 11:1928-1940.
-
(2012)
Mol Endocrinol
, vol.11
, pp. 1928-1940
-
-
Ustione, A.1
Piston, D.W.2
-
128
-
-
84867189044
-
Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase
-
Vetterli L, Carobbio S, Pournourmohammadi S, Martin-Del-Rio R, Skytt DM, Waagepetersen HS, Tamarit-Rodriguez J, Maechler P. 2012. Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase. Mol Biol Cell 23:3851-3862.
-
(2012)
Mol Biol Cell
, vol.23
, pp. 3851-3862
-
-
Vetterli, L.1
Carobbio, S.2
Pournourmohammadi, S.3
Martin-Del-Rio, R.4
Skytt, D.M.5
Waagepetersen, H.S.6
Tamarit-Rodriguez, J.7
Maechler, P.8
-
129
-
-
12144283149
-
Comparison of cellular and medium insulin and GABA content as markers for living beta-cells
-
Wang C, Ling Z, Pipeleers D. 2005. Comparison of cellular and medium insulin and GABA content as markers for living beta-cells. Am J Physiol Endocrinol Metab 288:E307-E313.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
, pp. E307-E313
-
-
Wang, C.1
Ling, Z.2
Pipeleers, D.3
-
130
-
-
0030757508
-
Possible evidence for endogenous production of a novel galanin-like peptide
-
Wang ZL, Kulkarni RN, Wang RM, Smith DM, Ghatei MA, Byfield PG, Bennet WM, Bloom SR. 1997. Possible evidence for endogenous production of a novel galanin-like peptide. J Clin Invest 100:189-196.
-
(1997)
J Clin Invest
, vol.100
, pp. 189-196
-
-
Wang, Z.L.1
Kulkarni, R.N.2
Wang, R.M.3
Smith, D.M.4
Ghatei, M.A.5
Byfield, P.G.6
Bennet, W.M.7
Bloom, S.R.8
-
131
-
-
0030470550
-
Multiple human receptors for pituitary adenylyl cyclase-activating polypeptide and vasoactive intestinal peptide are expressed in a tissue-specific manner
-
Wei Y, Mojsov S. 1996. Multiple human receptors for pituitary adenylyl cyclase-activating polypeptide and vasoactive intestinal peptide are expressed in a tissue-specific manner. Ann N Y Acad Sci 805:624-627.
-
(1996)
Ann N Y Acad Sci
, vol.805
, pp. 624-627
-
-
Wei, Y.1
Mojsov, S.2
-
132
-
-
84856655849
-
Activation of muscarinic receptors by non-neuronal acetylcholine
-
Wessler IK, Kirkpatrick CJ. 2012. Activation of muscarinic receptors by non-neuronal acetylcholine. Handb Exp Pharmacol 208:469-491.
-
(2012)
Handb Exp Pharmacol
, vol.208
, pp. 469-491
-
-
Wessler, I.K.1
Kirkpatrick, C.J.2
-
133
-
-
79955768520
-
Pancreatic beta cells synthesize neuropeptide Y and can rapidly release peptide co-transmitters
-
Whim MD. 2011. Pancreatic beta cells synthesize neuropeptide Y and can rapidly release peptide co-transmitters. PLoS ONE 6:e19478.
-
(2011)
PLoS ONE
, vol.6
, pp. e19478
-
-
Whim, M.D.1
-
134
-
-
84883745765
-
EXAMINE Investigators: Alogliptin after acute coronary syndrome in patients with type 2 diabetes
-
White WB, Cannon CP, Heller SR, Nissen SE, Bergenstal RM, Bakris GL, Perez AT, Fleck PR, Mehta CR, Kupfer S, Wilson C, Cushman WC, Zannad F. 2013. EXAMINE Investigators. Alogliptin after acute coronary syndrome in patients with type 2 diabetes. N Engl J Med 369:1327-1335.
-
(2013)
N Engl J Med
, vol.369
, pp. 1327-1335
-
-
White, W.B.1
Cannon, C.P.2
Heller, S.R.3
Nissen, S.E.4
Bergenstal, R.M.5
Bakris, G.L.6
Perez, A.T.7
Fleck, P.R.8
Mehta, C.R.9
Kupfer, S.10
Wilson, C.11
Cushman, W.C.12
Zannad, F.13
-
135
-
-
35748962950
-
A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice
-
Wideman RD, Covey SD, Webb GC, Drucker DJ, Kieffer TJ. 2007. A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice. Diabetes 56:2744-2752.
-
(2007)
Diabetes
, vol.56
, pp. 2744-2752
-
-
Wideman, R.D.1
Covey, S.D.2
Webb, G.C.3
Drucker, D.J.4
Kieffer, T.J.5
-
136
-
-
39149114759
-
Identification of glucose-dependant insulin secretion targets in pancreatic beta cells by combining defined-mechanism compound library screening and siRNA gene silencing
-
Wu W, Shang J, Feng Y, Thompson CM, Horwitz S, Thompson JR, MacIntyre ED, Thornberry NA, Chapman K, Zhou YP, Howard AD, Li J. 2008. Identification of glucose-dependant insulin secretion targets in pancreatic beta cells by combining defined-mechanism compound library screening and siRNA gene silencing. J Biomol Screen 13:128-134.
-
(2008)
J Biomol Screen
, vol.13
, pp. 128-134
-
-
Wu, W.1
Shang, J.2
Feng, Y.3
Thompson, C.M.4
Horwitz, S.5
Thompson, J.R.6
MacIntyre, E.D.7
Thornberry, N.A.8
Chapman, K.9
Zhou, Y.P.10
Howard, A.D.11
Li, J.12
-
137
-
-
0028054862
-
Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells
-
Yada T, Sakurada M, Ihida K, Nakata M, Murata F, Arimura A, Kikuchi M. 1994. Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells. J Biol Chem 269:1290-1293.
-
(1994)
J Biol Chem
, vol.269
, pp. 1290-1293
-
-
Yada, T.1
Sakurada, M.2
Ihida, K.3
Nakata, M.4
Murata, F.5
Arimura, A.6
Kikuchi, M.7
-
138
-
-
0031449347
-
Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet substance serving as an intra-islet amplifier of glucose-induced insulin secretion in rats
-
Yada T, Sakurada M, Ishihara H, Nakata M, Shioda S, Yaekura K, Hamakawa N, Yanagida K, Kikuchi M, Oka Y. 1997. Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet substance serving as an intra-islet amplifier of glucose-induced insulin secretion in rats. J Physiol 505:319-328.
-
(1997)
J Physiol
, vol.505
, pp. 319-328
-
-
Yada, T.1
Sakurada, M.2
Ishihara, H.3
Nakata, M.4
Shioda, S.5
Yaekura, K.6
Hamakawa, N.7
Yanagida, K.8
Kikuchi, M.9
Oka, Y.10
-
139
-
-
7044222788
-
Cytosolic Ca2+ responses to sub-picomolar and nanomolar PACAP in pancreatic beta-cells are mediated by VPAC2 and PAC1 receptors
-
Yamada H, Watanabe M, Yada T. 2004. Cytosolic Ca2+ responses to sub-picomolar and nanomolar PACAP in pancreatic beta-cells are mediated by VPAC2 and PAC1 receptors. Regul Pept 123:147-153.
-
(2004)
Regul Pept
, vol.123
, pp. 147-153
-
-
Yamada, H.1
Watanabe, M.2
Yada, T.3
-
140
-
-
12444252950
-
Overexpression of PACAP in transgenic mouse pancreatic beta-cells enhances insulin secretion and ameliorates streptozotocin-induced diabetes
-
Yamamoto K, Hashimoto H, Tomimoto S, Shintani N, Miyazaki J, Tashiro F, Aihara H, Nammo T, Li M, Yamagata K, Miyagawa J, Matsuzawa Y, Kawabata Y, Fukuyama Y, Koga K, Mori W, Tanaka K, Matsuda T, Baba A. 2003. Overexpression of PACAP in transgenic mouse pancreatic beta-cells enhances insulin secretion and ameliorates streptozotocin-induced diabetes. Diabetes 52:1155-1162.
-
(2003)
Diabetes
, vol.52
, pp. 1155-1162
-
-
Yamamoto, K.1
Hashimoto, H.2
Tomimoto, S.3
Shintani, N.4
Miyazaki, J.5
Tashiro, F.6
Aihara, H.7
Nammo, T.8
Li, M.9
Yamagata, K.10
Miyagawa, J.11
Matsuzawa, Y.12
Kawabata, Y.13
Fukuyama, Y.14
Koga, K.15
Mori, W.16
Tanaka, K.17
Matsuda, T.18
Baba, A.19
-
141
-
-
12944302589
-
Evidence for functional nicotinic receptors on pancreatic beta cells
-
Yoshikawa H, Hellström-Lindahl E, Grill V. 2005. Evidence for functional nicotinic receptors on pancreatic beta cells. Metabolism 54:247-254.
-
(2005)
Metabolism
, vol.54
, pp. 247-254
-
-
Yoshikawa, H.1
Hellström-Lindahl, E.2
Grill, V.3
-
142
-
-
84872586928
-
Serotonin receptor 2C and insulin secretion
-
Zhang Q, Zhu Y, Zhou W, Gao L, Yuan L, Han X. 2013. Serotonin receptor 2C and insulin secretion. PLoS ONE 8:e54250.
-
(2013)
PLoS ONE
, vol.8
, pp. e54250
-
-
Zhang, Q.1
Zhu, Y.2
Zhou, W.3
Gao, L.4
Yuan, L.5
Han, X.6
-
143
-
-
84937904927
-
Pancreatic endocrine effects of dopamine receptors in human islet cells
-
Zhang Y, Zheng R, Meng X, Wang L, Liu L, Gao Y. 2015. Pancreatic endocrine effects of dopamine receptors in human islet cells. Pancreas 44:925-929.
-
(2015)
Pancreas
, vol.44
, pp. 925-929
-
-
Zhang, Y.1
Zheng, R.2
Meng, X.3
Wang, L.4
Liu, L.5
Gao, Y.6
|