A switch from Prohormone Convertase (PC)-2 to PC1/3 expression in transplanted α-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice

Diabetes

Volumn 56, Issue 11, 2007, Pages 2744-2752

  Wideman, Rhonda D ^a   Covey, Scott D ^a   Webb, Gene C ^b   Drucker, Daniel J ^c   Kieffer, Timothy J ^a,d  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF CHICAGO   (United States)

^c MOUNT SINAI HOSPITAL   (Canada)

^d 2350 Health Sciences Mall ^*  (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 2; PROGLUCAGON; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIVISION; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROLLED STUDY; DRUG EFFECT; GLUCAGON BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HISTOPATHOLOGY; HYPERGLYCEMIA; HYPOPLASIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; GLUCAGON-SECRETING CELLS; GLUCOSE; GLUCOSE TOLERANCE TEST; ISLETS OF LANGERHANS; MALE; MICE; MICE, KNOCKOUT; PROGLUCAGON; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2; RECEPTORS, GLUCAGON;

EID: 35748962950     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db07-0563     Document Type: Article

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