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Volumn 288, Issue 2 51-2, 2005, Pages

Comparison of cellular and medium insulin and GABA content as markers for living β-cells

Author keywords

cell death; aminobutyric acid; Diabetes; Islet

Indexed keywords

3 (3,4 DICHLOROPHENYL) 1,2,3,4 OXATRIAZOLE 5 IMINE; 4 AMINOBUTYRIC ACID; BIOLOGICAL MARKER; GLUCOSE; INSULIN; INTERLEUKIN 1BETA; STREPTOZOCIN;

EID: 12144283149     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00222.2004     Document Type: Article
Times cited : (18)

References (30)
  • 4
    • 0020600266 scopus 로고
    • Fluorometric quantification of DNA in cells and tissue
    • Downs TR and Wilfinger WW. Fluorometric quantification of DNA in cells and tissue. Anal Biochem 131: 538-547, 1983.
    • (1983) Anal Biochem , vol.131 , pp. 538-547
    • Downs, T.R.1    Wilfinger, W.W.2
  • 5
    • 0023109786 scopus 로고
    • Ultrastructural localization of gamma amino butyric acid immunoreactivity in B cells of the rat pancreas
    • Garry DJ, Sorenson RL, and Coulter HD. Ultrastructural localization of gamma amino butyric acid immunoreactivity in B cells of the rat pancreas. Diabetologia 30: 115-119, 1987.
    • (1987) Diabetologia , vol.30 , pp. 115-119
    • Garry, D.J.1    Sorenson, R.L.2    Coulter, H.D.3
  • 7
    • 0029797603 scopus 로고    scopus 로고
    • Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program
    • Hoorens A, Van de Casteele M, Kloppel G, and Pipeleers D. Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program. J Clin Invest 98: 1568-1574, 1996.
    • (1996) J Clin Invest , vol.98 , pp. 1568-1574
    • Hoorens, A.1    Van De Casteele, M.2    Kloppel, G.3    Pipeleers, D.4
  • 8
    • 0029966752 scopus 로고    scopus 로고
    • Long-term metabolic control by rat islet grafts depends on the composition of the implant
    • Keymeulen B, Korbutt G, De Paepe M, Gorus F, Kloppel G, and Pipeleers DG. Long-term metabolic control by rat islet grafts depends on the composition of the implant. Diabetes 45: 1814-1821, 1996.
    • (1996) Diabetes , vol.45 , pp. 1814-1821
    • Keymeulen, B.1    Korbutt, G.2    De Paepe, M.3    Gorus, F.4    Kloppel, G.5    Pipeleers, D.G.6
  • 9
    • 6844239526 scopus 로고    scopus 로고
    • Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: Graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft
    • Keymeulen B, Ling Z, Gorus FK, Delvaux G, Bouwens L, Grupping A, Hendrieckx C, Pipeleers-Marichal M, Van Schravendijk C, Salmela K, and Pipeleers DG. Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft. Diabetologia 41: 452-459, 1998.
    • (1998) Diabetologia , vol.41 , pp. 452-459
    • Keymeulen, B.1    Ling, Z.2    Gorus, F.K.3    Delvaux, G.4    Bouwens, L.5    Grupping, A.6    Hendrieckx, C.7    Pipeleers-Marichal, M.8    Van Schravendijk, C.9    Salmela, K.10    Pipeleers, D.G.11
  • 11
    • 0030467497 scopus 로고    scopus 로고
    • Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation
    • Ling Z and Pipeleers DG. Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation. J Clin Invest 98: 2805-2812, 1996.
    • (1996) J Clin Invest , vol.98 , pp. 2805-2812
    • Ling, Z.1    Pipeleers, D.G.2
  • 12
    • 0033625664 scopus 로고    scopus 로고
    • Interleukin-1 beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis
    • Ling Z, Van de Casteele M, Eizirik DL, and Pipeleers DG. Interleukin-1 beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis. Diabetes 49: 340-345, 2000.
    • (2000) Diabetes , vol.49 , pp. 340-345
    • Ling, Z.1    Van De Casteele, M.2    Eizirik, D.L.3    Pipeleers, D.G.4
  • 13
    • 0031838429 scopus 로고    scopus 로고
    • Isolation, culture and functional evaluation of islets of Langerhans
    • London NJ, Swift SM, and Clayton HA. Isolation, culture and functional evaluation of islets of Langerhans. Diabetes Metab 24: 200-207, 1998.
    • (1998) Diabetes Metab , vol.24 , pp. 200-207
    • London, N.J.1    Swift, S.M.2    Clayton, H.A.3
  • 14
    • 0026755223 scopus 로고
    • GABA in pancreatic islets: Metabolism and function
    • Michalik M and Erecinska M. GABA in pancreatic islets: metabolism and function. Biochem Pharmacol 44: 1-9, 1992.
    • (1992) Biochem Pharmacol , vol.44 , pp. 1-9
    • Michalik, M.1    Erecinska, M.2
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63, 1983.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 16
    • 0033583068 scopus 로고    scopus 로고
    • Alpha-soluble N-ethylmaleimide-sensitive factor attachment protein is expressed in pancreatic beta cells and functions in insulin but not gamma-aminobutyric acid secretion
    • Nagamatsu S, Watanabe T, Nakamichi Y, Yamamura C, Tsuzuki K, and Matsushima S. alpha-soluble N-ethylmaleimide-sensitive factor attachment protein is expressed in pancreatic beta cells and functions in insulin but not gamma-aminobutyric acid secretion. J Biol Chem 274: 8053-8060, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 8053-8060
    • Nagamatsu, S.1    Watanabe, T.2    Nakamichi, Y.3    Yamamura, C.4    Tsuzuki, K.5    Matsushima, S.6
  • 17
    • 0017148989 scopus 로고
    • High concentration of GABA and high glutamate decarboxylase activity in rat pancreatic islets and human insulinoma
    • Okada Y, Taniguchi H, and Schimada C. High concentration of GABA and high glutamate decarboxylase activity in rat pancreatic islets and human insulinoma. Science 194: 620-622, 1976.
    • (1976) Science , vol.194 , pp. 620-622
    • Okada, Y.1    Taniguchi, H.2    Schimada, C.3
  • 18
    • 0013492650 scopus 로고
    • Pancreatic B cells possess defense mechanisms against cell-specific toxicity
    • Pipeleers D and Van de Winkel M. Pancreatic B cells possess defense mechanisms against cell-specific toxicity. Proc Natl Acad Sci USA 83: 5267-5271, 1986.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5267-5271
    • Pipeleers, D.1    Van De Winkel, M.2
  • 20
    • 0025875235 scopus 로고
    • GABA and pancreatic beta-cells: Colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion
    • Reetz A, Solimena M, Matteoli M, Folli F, Takei K, and De Camilli P. GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion. EMBO J 10: 1275-1284, 1991.
    • (1991) EMBO J , vol.10 , pp. 1275-1284
    • Reetz, A.1    Solimena, M.2    Matteoli, M.3    Folli, F.4    Takei, K.5    De Camilli, P.6
  • 23
    • 0023144181 scopus 로고
    • Immunohistochemical localization of gamma-aminobutyric acid (GABA) in the rat pancreas
    • Sakaue M, Saito N, and Tanaka C. Immunohistochemical localization of gamma-aminobutyric acid (GABA) in the rat pancreas. Histochemistry 86: 365-369, 1987.
    • (1987) Histochemistry , vol.86 , pp. 365-369
    • Sakaue, M.1    Saito, N.2    Tanaka, C.3
  • 25
  • 26
    • 0031438061 scopus 로고    scopus 로고
    • Nutrient regulation of gamma-aminobutyric acid release from islet beta cells
    • Smismans A, Schuit F, and Pipeleers D. Nutrient regulation of gamma-aminobutyric acid release from islet beta cells. Diabelologia 40: 1411-1415, 1997.
    • (1997) Diabelologia , vol.40 , pp. 1411-1415
    • Smismans, A.1    Schuit, F.2    Pipeleers, D.3
  • 27
    • 0028960028 scopus 로고
    • The analysis of excitatory, inhibitory and other amino acids in rat brain microdialysates using microbore liquid chromatography
    • Smolders I, Sarre S, Michotte Y, and Ebinger G. The analysis of excitatory, inhibitory and other amino acids in rat brain microdialysates using microbore liquid chromatography. J Neurosci Methods 57: 47-53, 1995.
    • (1995) J Neurosci Methods , vol.57 , pp. 47-53
    • Smolders, I.1    Sarre, S.2    Michotte, Y.3    Ebinger, G.4
  • 28
    • 0026803423 scopus 로고
    • Pancreatic beta cell heterogeneity in glucose-induced insulin secretion
    • Van Schravendijk CF, Kiekens R, and Pipeleers DG. Pancreatic beta cell heterogeneity in glucose-induced insulin secretion. J Biol Chem 267: 21344-21348, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 21344-21348
    • Van Schravendijk, C.F.1    Kiekens, R.2    Pipeleers, D.G.3
  • 29
    • 1842422955 scopus 로고    scopus 로고
    • Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells
    • Wendt A, Birnir B, Buschard K, Gromada J, Salehi A, Sewing S, Rorsman P, and Braun M. Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells. Diabetes 53: 1038-1045, 2004.
    • (2004) Diabetes , vol.53 , pp. 1038-1045
    • Wendt, A.1    Birnir, B.2    Buschard, K.3    Gromada, J.4    Salehi, A.5    Sewing, S.6    Rorsman, P.7    Braun, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.