The glial glutamate transporter 1 (GLT1) is expressed by pancreatic β-cells and prevents glutamate-induced β-cell death

Journal of Biological Chemistry

Volumn 286, Issue 16, 2011, Pages 14007-14018

  Di Cairano, Eliana S ^a   Davalli, Alberto M ^b,c   Perego, Lucia ^a   Sala, Silvia ^a   Sacchi, V Franca ^a   La Rosa, Stefano ^e   Finzi, Giovanna ^e   Placidi, Claudia ^e   Capella, Carlo ^e   Conti, Paola ^a   Centonze, Victoria E ^d   Casiraghi, Francesca ^c   Bertuzzi, Federico ^f   Folli, Franco ^c,d   Perego, Carla ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^e UNIVERSITY OF INSUBRIA   (Italy)

^f OSPEDALE NIGUARDA CA GRANDA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; AUTOPHAGY; CELL LINES; CELL SURVIVAL; CELL VIABILITY; CENTRAL NERVOUS SYSTEMS; CHRONIC EXPOSURE; CYTOTOXIC EFFECTS; DOWN-REGULATION; EXTRACELLULAR; EXTRACELLULAR CONCENTRATION; GLUTAMATE RECEPTOR; GLUTAMATE TRANSPORTERS; HIGH AFFINITY; HUMAN ISLETS; KEY REGULATORS; LANGERHANS; PHYSIOLOGICAL CONCENTRATIONS; PLASMA MEMBRANES; SIGNALING MOLECULES; SOLUTE CARRIERS; UP-REGULATION;

CARRIER CONCENTRATION; CELL CULTURE; CELL DEATH; CELL MEMBRANES; CYTOTOXICITY; PHYSIOLOGY; SIGNALING;

CLONE CELLS;

GLIAL GLUTAMATE TRANSPORTER 1; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CELL DEATH; CELL MEMBRANE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; GLUCAGON RELEASE; HORMONE RELEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; UPREGULATION;

ANIMALS; APOPTOSIS; AUTOPHAGY; CELL SURVIVAL; EXCITATORY AMINO ACID TRANSPORTER 2; GENE EXPRESSION REGULATION; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; GLUTAMIC ACID; HOMEOSTASIS; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MICE; MODELS, BIOLOGICAL; OXIDATIVE STRESS;

EID: 79954570143     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.183517     Document Type: Article

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