Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenylyl cyclase in RIN 5AH rat insulinoma cells

Diabetologia

Volumn 41, Issue 12, 1998, Pages 1482-1491

  Morgan, D G ^a   Kulkarni, R N ^b   Hurley, J D ^c   Wang, Z L ^a   Wang, R M ^a   Ghatei, M A ^a   Karlsen, A E ^d   Bloom, S R ^a   Smith, D M ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD INSTITUTES OF MEDICINE   (United States)

^d STENO DIABETES CENTER   (Denmark)

Author keywords

Insulin secretion; Insulinoma cells; Neuropeptide Y; Y1 receptor

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; GLUCAGON; ISOPRENALINE; NALPHA (DIPHENYLACETYL) N (4 HYDROXYBENZYL) DEXTRO ARGININAMIDE; NEUROPEPTIDE Y; NEUROPEPTIDE Y1 RECEPTOR; OXIDOPAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BINDING AFFINITY; CELL CULTURE; CELL LYSATE; DRUG POTENCY; ENZYME ACTIVITY; INSULIN BLOOD LEVEL; INSULINOMA; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN SECRETION; RADIOIMMUNOASSAY; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING; SYMPATHETIC NERVE;

ADENYLATE CYCLASE; ANIMALS; BLOTTING, NORTHERN; CYCLIC AMP; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; INSULIN; INSULINOMA; IODINE RADIOISOTOPES; ISOPROTERENOL; NEUROPEPTIDE Y; PANCREATIC NEOPLASMS; PEPTIDE FRAGMENTS; PEPTIDE YY; PROTEIN PRECURSORS; RATS; RECEPTORS, NEUROPEPTIDE Y; SWINE; TUMOR CELLS, CULTURED;

EID: 0031797940     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051095     Document Type: Article

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