Comparative effects of PACAP and VIP on pancreatic endocrine secretions and vascular resistance in rat

British Journal of Pharmacology

Volumn 117, Issue 4, 1996, Pages 764-770

  Bertrand, G ^a,b   Puech, R ^a,b   Maisonnasse, Y ^a   Bockaert, J ^a   Loubatieres Mariani M M ^b  

^a INSERM   (France)

^b Institute of Biology   (France)

Author keywords

Glucagon secretion; Insulin secretion; Pituitary adenylate cyclase activating polypeptide (PACAP); Rat pancreas; Secretin; Vasoactive intestinal peptide (VIP); Vessel

Indexed keywords

GLUCAGON; GLUCOSE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; INSULIN; RECEPTOR SUBTYPE; SECRETIN; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; GLUCAGON RELEASE; INSULIN RELEASE; ISOLATED ORGAN; MALE; NONHUMAN; PANCREAS BLOOD FLOW; PANCREAS ISLET; PANCREAS SECRETION; PRIORITY JOURNAL; RAT; VASCULAR RESISTANCE;

EID: 0030060951     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15256.x     Document Type: Article

References (32)

1. ABSOOD, A., CHEN, D., WANG, Z.Y. & HAKANSON, R. (1992). Vascular effects of pituitary adenylate cyclase activating peptide: a comparison with vasoactive intestinal peptide. Regulat. Pept., 40, 323-329.
2. ARIMURA, A. (1992). Pituitary adenylate cyclase activating poly-peptide (PACAP): discovery and current status of research. Regulat. Pept., 37, 287-303.
3. ARIMURA, A. & SHIODA, S. (1995). Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors: neuroendocrine and endocrine interaction. Front Neuroendocrinol., 16, 53-88.
4. ARMITAGE, P. (1980). Biological assay. In Statistical Methods in Medical Research, ed. Armitage P. pp. 442-456. Oxford: Blackwell.
5. BERTRAND, G. , CHAPAL, J. & LOUBATIERES-MARIANI, M.M. (1986). Potentiating synergism between adenosine diphosphate or triphosphate and acetylcholine on insulin secretion. Am. J. Physiol., 251, E416-E421.
6. BISHOP, A.E., POLAK, J.M., GREEN, I.C., BRYANT, M.G. & BLOOM, S.R. (1980). The location of VIP in the pancreas of man and rat. Diabetologia, 18, 73-78.
7. CHRISTOPHE, J. (1993). Type I receptors for PACAP (a neuropeptide even more important that VIP?). Biochim. Biophys. Acta., 1154, 183-199.
8. FRIDOLF, T., SUNDLER, F. & AHREN, B. (1992). Pituitary adenylate cyclase-activating polypeptide (PACAP): occurrence in rodent pancreas and effects on insulin and glucagon secretion in the mouse. Cell Tissue Res., 269, 275-279.
9. HARMAR, T. & LUTZ, E.M. (1994). Multiple receptors for PACAP and VIP. Trends Pharmacol. Sci., 15, 97-99.
10. HERBERT, V., LAW, K.S., GOTTLIEB, C.W. & BLEICHER, S.J. (1965). Coated charcoal immunoassay of insulin. J. Clin. Endocrinol., 25, 1375-1384.
11. HUANG, M., SHIRAHASE, H. & RORSTAD, O.P. (1993). Comparative study of vascular relaxation and receptor binding by PACAP and VIP. Peptides, 14, 755-762.
12. INAGAKI, N., YOSHIDA, H., MIZUTA, M., MIZUNO, N., FUJIII, Y., GONOI, Y., MIYAZAKI, J.I. & SEINO, S. (1994). Cloning and functional characterization of a third pituitary adenylate cyclase-activating polypeptide receptor subtype expressed in insulin-secreting cells. Proc. Natl. Acad. Sci. U.S.A., 91, 2679-2683.
13. ISHIHARA, T., SHIGEMOTO, T., MORI, K., TAKAHASHI, K. & NAGATA, S. (1992). Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide. Neuron, 8, 811-819.
14. JANSSON, L. (1994). Vasoactive intestinal polypeptide increases whole pancreatic blood flow but does not affect islet blood flow in the rat. Acta Diabetol., 31, 103-106.
15. KAWAI, K., OHSE, C., WATANABE, Y., SUZUKI, S., YAMASHITA, K. & OHASHI, S. (1991). Pituitary adenylate cyclase activating polypeptide stimulates insulin release from the isolated perfused rat pancreas. Life Sci., 50, 257-261.
16. KÖVES, K., ARIMURA, A., VIGH, S., SOMOGYVARI-VIGH, A. & MILLER, J. (1993). Immunohistochemical localization of PACAP in the ovine digestive system. Peptides, 14, 449-455.
17. LE NGUYEN, D., HEITZ, A. & CASTRO, B. (1987). Rapid solid-phase synthesis of the rattine sequence tetradecapeptide using BOP reagent. J. Chem. Soc. Perkin Trans., I, 1915-1919.
18. LOUBATIERES, A.L., MARIANI, M.M., DE MALBOSC, H., RIBES, G. & CHAPAL, J. (1969). Etude expérimentale d'un nouveau sulfamide hypoglycémiant particulièrement actif, le HB 419 ou glibenclamide. I. Action bêtacytotrope et insulino-sécrétrice. Diabetologia, 5, 1-10.
19. 2 receptor: molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide. FEBS Letts., 334, 3-8.
20. MINKES, R.K., MCMAHON, T.J., HIGUERA, T.R., MURPHY, W.A., COY, D.H. & KADOWITZ, P.J. (1992). Analysis of systemic and pulmonary vascular responses to PACAP and VIP: role of adrenal catecholamines. Am. J. Physiol., 263, H1659-H1669.
21. MIYATA, A., ARIMURA, A., DAHL, R.D., MINAMINO, N., UEHARA, A., JIANG, L., CULLER, M.D. & COY, D.H. (1989). Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem. Biophys. Res. Commun.,164, 567-574.
22. MIYATA, A., JIANG, L., DAHL, R.D., KITADA, C., KUBO, K., FUJINO, M., MINAMINO, N. & ARIMURA, A. (1990). Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38). Biochem. Biophys. Res. Commun., 170, 643-648.
23. NANDHA, K.A., BENITO-ORFILA, M.A., SMITH, D.M., GHATEI, M.A. & BLOOM, S.R. (1991). Action of pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal polypeptide on the rat vascular system: effects on blood pressure and receptor binding. J. Endocrinol., 129, 69-73.
24. RAWLINGS, S.R. (1994). PACAP, PACAP receptors, and intracellular signalling. Mol. Cell. Endocrinol., 101, C5-C9.
25. SANTIAGO, J.A. & KADOWITZ, P.J. (1993). Analysis of responses to pituitary adenylate cyclase activating polypeptide-38 in the feline hindquarters vascular bed. Eur. J. Pharmacol., 243, 291-294.
26. SCHEBALIN, M., SAID, S.I. & MAKHLOUF, G.M. (1977). Stimulation of insulin and glucagon secretion by vasoactive intestinal peptide. Am. J. Physiol., 232, E197-E200.
27. SZECOWKA, J., SANDBERG, E. & EFENDIC, S. (1980). The interaction of vasoactive intestinal polypeptide (VIP), glucose and arginine on the secretion of insulin, glucagon and somatostatin in the perfused rat pancreas. Diabetologia, 19, 137-142.
28. UNGER, R.H., AGUILAR-PARADA, E., MULLER, W. & EISENTRAUT, A.M. (1970). Studies of pancreatic alpha cell function in normal and diabetic subjects. J. Clin. Invest., 49, 837-848.
29. USDIN, T.B., BONNER, T.I. & MEZEY, E. (1994). Two receptors for vasoactive intestinal polypeptide with similar specificity and complementary distributions. Endocrinology, 135, 2662-2680.
30. WARREN, J.B., DONNELLY, L.E., CULLEN, S., ROBERTSON, B.E., GHATEI, M.A., BLOOM, S.T. & MAC-DERMOT, J. (1991). Pituitary adenylate cyclase-activating polypeptide: a novel, long-lasting, endothelium-independent vasorelaxant. Eur. J. Pharmacol., 197, 131-134.
31. YADA, T., SAKURADA, M., IHIDA, K., NAKATA, M., MURATA, F., ARIMURA, A. & KIKUCHI, M. (1994). Pituitary adenylate cyclase activating polypeptide is an extraordinary potent intra-pancreatic regulator of insulin secretion from islet β-cells. J. Biol. Chem., 269, 1290-1293.
32. YOKOTA, C., KAWAI, K., OHASHI, S., WATANABE, Y., SUZUKI, S. & YAMASHITA, K. (1993). Stimulatory effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on insulin and glucagon release from the isolated perfused rat pancreas. Acta Endocrinol., 129, 473-479.