Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility

Diabetic Medicine

Volumn 31, Issue 8, 2014, Pages 1001-1008

  Guigas, B ^a   de Leeuw van Weenen, J E ^a   van Leeuwen, N ^a   Simonis Bik, A M ^b   van Haeften, T W ^c   Nijpels, G ^d   Houwing Duistermaat, J J ^a   Beekman, M ^a   Deelen, J ^a   Havekes, L M ^a,e   Penninx, B W J H ^b,d   Vogelzangs, N ^b,d   van 't Riet, E ^d   Dehghan, A ^f,g   Hofman, A ^f,g   Witteman, J C ^f,g   Uitterlinden, A G ^f,g   Grarup, N ^h   Jorgensen T ^h,i   Witte, D R ^j   Lauritzen, T ^k   Hansen, T ^h,l   Pedersen, O ^h   Hottenga, J ^m   Romijn, J A ^a   Diamant, M ^b   Kramer, M H H ^b   Heine, R J ^b,d,n   Willemsen, G ^m   Dekker, J M ^d   Eekhoff, E M ^b   Pijl, H ^a   de Geus, E J ^m   Slagboom, P E ^a   't Hart, L M ^a   more..

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^e TNO   (Netherlands)

^f ERASMUS MEDICAL CENTER   (Netherlands)

^g Netherlands Genomics Initiative   (Netherlands)

^h UNIVERSITY OF COPENHAGEN   (Denmark)

ⁱ GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

^j STENO DIABETES CENTER   (Denmark)

^k AARHUS UNIVERSITY   (Denmark)

^l UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^m VU UNIVERSITY AMSTERDAM   (Netherlands)

ⁿ ELI LILLY AND COMPANY   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 2 RECEPTOR; GLUCOSE; INSULIN; ANKK1 PROTEIN, HUMAN; DRD2 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE;

ADULT; AGED; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC CODE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; INSULIN RELEASE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; POPULATION BASED CASE CONTROL STUDY; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; BLOOD; CASE CONTROL STUDY; DENMARK; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; HYPERGLYCEMIA; INSULIN RESISTANCE; METABOLISM; MIDDLE AGED; NETHERLANDS; SECRETION (PROCESS); SEXUAL DEVELOPMENT;

ALLELES; CASE-CONTROL STUDIES; COHORT STUDIES; DENMARK; DIABETES MELLITUS, TYPE 2; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; NETHERLANDS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, DOPAMINE D2; SEX CHARACTERISTICS;

EID: 84904347822     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/dme.12464     Document Type: Article

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