-
1
-
-
0030016329
-
Apoptosis induction resulting from Proteasome inhibition
-
Shinohara K et al. Apoptosis induction resulting from Proteasome inhibition. J Biochem 1996 317 : 385 388.
-
(1996)
J Biochem
, vol.317
, pp. 385-388
-
-
Shinohara, K.1
-
2
-
-
0032512622
-
Protease inhibitors protect macrophages from lipopolysaccharide-induced cytotoxicity: Possible role for NF- kappa B
-
Abate A, Schroder H. Protease inhibitors protect macrophages from lipopolysaccharide-induced cytotoxicity: possible role for NF- kappa B. Life Sci 1998 62 : 1081 1088.
-
(1998)
Life Sci
, vol.62
, pp. 1081-1088
-
-
Abate, A.1
Schroder, H.2
-
3
-
-
0036753558
-
In situ activation of caspases and serine proteases during apoptosis detected by affinity labeling their enzyme active centers with fluorochrome-tagged inhibitors
-
Grabarek J, Darzynkiewicz Z. In situ activation of caspases and serine proteases during apoptosis detected by affinity labeling their enzyme active centers with fluorochrome-tagged inhibitors. Exp Hematol 2002 30 : 982 989.
-
(2002)
Exp Hematol
, vol.30
, pp. 982-989
-
-
Grabarek, J.1
Darzynkiewicz, Z.2
-
4
-
-
0041825824
-
A novel serine protease predominately expressed in macrophages
-
Chen C et al. A novel serine protease predominately expressed in macrophages. J Biochem 2003 374 : 97 107.
-
(2003)
J Biochem
, vol.374
, pp. 97-107
-
-
Chen, C.1
-
5
-
-
27944454061
-
Characterization of a serine protease-mediated cell death program activated in human leukemia cells
-
O'Connell AR et al. Characterization of a serine protease-mediated cell death program activated in human leukemia cells. Exp Cell Res 2006 312 : 27 39.
-
(2006)
Exp Cell Res
, vol.312
, pp. 27-39
-
-
O'Connell, A.R.1
-
8
-
-
0030970119
-
Emerging roles for cysteine proteases in human biology
-
Chapman HA et al. Emerging roles for cysteine proteases in human biology. Annu Rev Physiol 1997 59 : 63 88.
-
(1997)
Annu Rev Physiol
, vol.59
, pp. 63-88
-
-
Chapman, H.A.1
-
9
-
-
0029060166
-
Proteasome from Thermoplasma acidophilum: A threonine protease
-
Seemuller E et al. Proteasome from Thermoplasma acidophilum: a threonine protease. Science 1995 268 : 579.
-
(1995)
Science
, vol.268
, pp. 579
-
-
Seemuller, E.1
-
12
-
-
0642345204
-
In the cut and thrust of apoptosis, serine proteases come of age
-
Stenson-Cox C et al. In the cut and thrust of apoptosis, serine proteases come of age. Biochem Pharmacol 2003 66 : 1469 1474.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 1469-1474
-
-
Stenson-Cox, C.1
-
14
-
-
0029962944
-
Conservation and variability in the structures of serine proteinases of the chymotrypsin family
-
Lesk AM, Fordham WD. Conservation and variability in the structures of serine proteinases of the chymotrypsin family. J Mol Biol 1996 258 : 501 537.
-
(1996)
J Mol Biol
, vol.258
, pp. 501-537
-
-
Lesk, A.M.1
Fordham, W.D.2
-
15
-
-
0028914722
-
Structural basis of substrate specificity in the serine proteases
-
Perona JJ, Craik CS. Structural basis of substrate specificity in the serine proteases. Protein Sci 1995 4 : 337 360.
-
(1995)
Protein Sci
, vol.4
, pp. 337-360
-
-
Perona, J.J.1
Craik, C.S.2
-
16
-
-
0032250184
-
Serpins and regulation of cell death
-
Bird PI. Serpins and regulation of cell death. Results Probl Cell Differ 1998 24 : 63 89.
-
(1998)
Results Probl Cell Differ
, vol.24
, pp. 63-89
-
-
Bird, P.I.1
-
17
-
-
0035500490
-
The many faces of metalloproteases: Cell growth, invasion, angiogenesis and metastasis
-
Chang C, Werb Z. The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol 2001 11 : S37 43.
-
(2001)
Trends Cell Biol
, vol.11
, pp. 37-43
-
-
Chang, C.1
Werb, Z.2
-
18
-
-
0028073883
-
The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis
-
Ray JM, Stetler-Stevenson WG. The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis. Eur Respir J 1994 7 : 2062 2072.
-
(1994)
Eur Respir J
, vol.7
, pp. 2062-2072
-
-
Ray, J.M.1
Stetler-Stevenson, W.G.2
-
19
-
-
0035188727
-
How metalloproteases regulate cell behaviour
-
Sternlicht MD, Werb Z. How metalloproteases regulate cell behaviour. Annu Rev Cell Dev Biol 2001 17 : 463 516.
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
20
-
-
0023477907
-
Human immunodeficiency virus protease expressed in Escherichia coli exhibits autoprocessing and specific maturation of the gag precursor
-
Debouck C et al. Human immunodeficiency virus protease expressed in Escherichia coli exhibits autoprocessing and specific maturation of the gag precursor. Proc Nat Acad Sci U S A 1987 84 : 8903 8906.
-
(1987)
Proc Nat Acad Sci U S A
, vol.84
, pp. 8903-8906
-
-
Debouck, C.1
-
21
-
-
1542723495
-
The molecular structure and catalytic mechanism of a novel carboxyl peptidase from Scytalidium lignicolum
-
Fujinaga M et al. The molecular structure and catalytic mechanism of a novel carboxyl peptidase from Scytalidium lignicolum. Proc Nat Acad Sci U S A 2004 101 : 3364 3369.
-
(2004)
Proc Nat Acad Sci U S A
, vol.101
, pp. 3364-3369
-
-
Fujinaga, M.1
-
22
-
-
4644324164
-
Glutamic protease distribution is limited to filamentous fungi
-
Sims AH et al. Glutamic protease distribution is limited to filamentous fungi. FEMS Microbiol Lett 2004 239 : 95 101.
-
(2004)
FEMS Microbiol Lett
, vol.239
, pp. 95-101
-
-
Sims, A.H.1
-
23
-
-
0037138438
-
Lysosomal proteases as potential targets for the induction of apoptotic cell death in human neuroblastomas
-
Castino R et al. Lysosomal proteases as potential targets for the induction of apoptotic cell death in human neuroblastomas. Int J Cancer 2002 97 : 775 779.
-
(2002)
Int J Cancer
, vol.97
, pp. 775-779
-
-
Castino, R.1
-
24
-
-
0033832629
-
Noncaspase proteases in apoptosis
-
Johnson DE. Noncaspase proteases in apoptosis. Leukemia 2000 14 : 1695 1703.
-
(2000)
Leukemia
, vol.14
, pp. 1695-1703
-
-
Johnson, D.E.1
-
25
-
-
0032806132
-
Ionizing radiation-induced, Bax-mediated cell death is dependent on activation of cysteine and serine proteases
-
Gong B et al. Ionizing radiation-induced, Bax-mediated cell death is dependent on activation of cysteine and serine proteases. Cell Growth Diff 1999 10 : 491 502.
-
(1999)
Cell Growth Diff
, vol.10
, pp. 491-502
-
-
Gong, B.1
-
26
-
-
0141893341
-
Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions
-
Egger L et al. Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions. Cell Death Diff 2003 10 : 1188 1203.
-
(2003)
Cell Death Diff
, vol.10
, pp. 1188-1203
-
-
Egger, L.1
-
27
-
-
33749162486
-
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
-
Yousefi S et al. Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 2006 8 : 1124 1132.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1124-1132
-
-
Yousefi, S.1
-
28
-
-
0027474051
-
Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: A potential molecular basis for neuronal degeneration
-
Saito K et al. Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration. Proc Natl Acad Sci U S A 1993 90 : 2628 2632.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 2628-2632
-
-
Saito, K.1
-
29
-
-
0029782494
-
Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha
-
Deiss LP et al. Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha. EMBO J 1996 15 : 3861 3870.
-
(1996)
EMBO J
, vol.15
, pp. 3861-3870
-
-
Deiss, L.P.1
-
30
-
-
0032580334
-
Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity
-
Wu GS et al. Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity. Oncogene 1998 16 : 2177 2183.
-
(1998)
Oncogene
, vol.16
, pp. 2177-2183
-
-
Wu, G.S.1
-
31
-
-
0032500842
-
Participation of cathepsins B and D in apoptosis of PC12 cells following serum deprivation
-
Shibata M et al. Participation of cathepsins B and D in apoptosis of PC12 cells following serum deprivation. Biochem Biophys Res Commun 1998 251 : 199 203.
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 199-203
-
-
Shibata, M.1
-
32
-
-
0033756474
-
Cathepsin B contributes to TNF-α-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
-
Guicciardi ME et al. Cathepsin B contributes to TNF-α-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J Clin Invest 2000 106 : 1127 1137.
-
(2000)
J Clin Invest
, vol.106
, pp. 1127-1137
-
-
Guicciardi, M.E.1
-
33
-
-
0034025876
-
Z-Phe-Gly-NHO-Bz, an inhibitor of cysteine cathepsins, induces apoptosis in human cancer cells
-
Zhu D-M, Uckun FM. Z-Phe-Gly-NHO-Bz, an inhibitor of cysteine cathepsins, induces apoptosis in human cancer cells. Clin Cancer Res 2000 6 : 2064 2069.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2064-2069
-
-
Zhu, D.-M.1
Uckun, F.M.2
-
34
-
-
0034739734
-
Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates
-
Yamashima T. Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates. Prog Neurobiol 2000 62 : 273 295.
-
(2000)
Prog Neurobiol
, vol.62
, pp. 273-295
-
-
Yamashima, T.1
-
35
-
-
0028959720
-
Cathepsin B in predicting the extent of the cervix carcinoma
-
Makarewicz R et al. Cathepsin B in predicting the extent of the cervix carcinoma. Neoplasma 1995 42 : 21 24.
-
(1995)
Neoplasma
, vol.42
, pp. 21-24
-
-
Makarewicz, R.1
-
36
-
-
0029838059
-
Biological and clinical significance of cathepsin D in breast cancer metastasis
-
Garcia M et al. Biological and clinical significance of cathepsin D in breast cancer metastasis. Stem Cells 1996 14 : 642 650.
-
(1996)
Stem Cells
, vol.14
, pp. 642-650
-
-
Garcia, M.1
-
37
-
-
0037969805
-
The clinical significance of cathepsin S expression in human astrocytomas
-
Flannery T et al. The clinical significance of cathepsin S expression in human astrocytomas. Am J Pathol 2003 163 : 175 182.
-
(2003)
Am J Pathol
, vol.163
, pp. 175-182
-
-
Flannery, T.1
-
38
-
-
33745918920
-
Cathepsin S expression: An independent prognostic factor in glioblastoma tumours - A pilot study
-
Flannery T et al. Cathepsin S expression: an independent prognostic factor in glioblastoma tumours-a pilot study. Int J Cancer 2006 119 : 854 860.
-
(2006)
Int J Cancer
, vol.119
, pp. 854-860
-
-
Flannery, T.1
-
39
-
-
20044383567
-
Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death
-
Emert-Sedlak L et al. Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death. Mol Cancer Ther 2005 4 : 733 742.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 733-742
-
-
Emert-Sedlak, L.1
-
40
-
-
0028947294
-
Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: Evidence for early up-regulation of the endosomal-lysosomal system
-
Cataldo AM et al. Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system. Neuron 1995 14 : 671 680.
-
(1995)
Neuron
, vol.14
, pp. 671-680
-
-
Cataldo, A.M.1
-
41
-
-
0030862412
-
Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes
-
Roberts LR et al. Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes. Gastroenterology 1997 113 : 1714 1726.
-
(1997)
Gastroenterology
, vol.113
, pp. 1714-1726
-
-
Roberts, L.R.1
-
42
-
-
0037062449
-
Neuronal loss and brain atrophy in mice lacking cathepsins B and L
-
Felbor U et al. Neuronal loss and brain atrophy in mice lacking cathepsins B and L. Proc Natl Acad Sci U S A 2002 99 : 7883 7888.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 7883-7888
-
-
Felbor, U.1
-
43
-
-
2142773262
-
Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: A possible mechanism of high dose tolerance
-
Michallet MC et al. Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: a possible mechanism of high dose tolerance. J Immunol 2004 172 : 5405 5414.
-
(2004)
J Immunol
, vol.172
, pp. 5405-5414
-
-
Michallet, M.C.1
-
44
-
-
17344370810
-
Uptake of oxidized LDL by macrophages results in partial lysosomal enzyme inactivation and relocation
-
Li W et al. Uptake of oxidized LDL by macrophages results in partial lysosomal enzyme inactivation and relocation. Arterioscler Thromb Vasc Biol 1998 18 : 177 184.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 177-184
-
-
Li, W.1
-
45
-
-
0031897739
-
Oxidative stress causes relocation of the lysosomal enzyme cathepsin D with ensuing apoptosis in neonatal rat cardiomyocytes
-
Roberg K, Ollinger K. Oxidative stress causes relocation of the lysosomal enzyme cathepsin D with ensuing apoptosis in neonatal rat cardiomyocytes. Am J Pathol 1998 152 : 1151 1156.
-
(1998)
Am J Pathol
, vol.152
, pp. 1151-1156
-
-
Roberg, K.1
Ollinger, K.2
-
46
-
-
0031793017
-
Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity
-
Vancompernolle K et al. Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity. FEBS Lett 1998 438 : 150 158.
-
(1998)
FEBS Lett
, vol.438
, pp. 150-158
-
-
Vancompernolle, K.1
-
47
-
-
0242609099
-
Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine
-
Johansson AC et al. Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine. Cell Death Differ 2003 10 : 1253 1259.
-
(2003)
Cell Death Differ
, vol.10
, pp. 1253-1259
-
-
Johansson, A.C.1
-
48
-
-
34247849157
-
Cathepsin-cleaved Bid promotes apoptosis in human neutrophils via oxidative stress-induced lysosomal membrane permeabilization
-
Blomgran R et al. Cathepsin-cleaved Bid promotes apoptosis in human neutrophils via oxidative stress-induced lysosomal membrane permeabilization. J Leukocyte Biol 2007 81 : 1213 1223.
-
(2007)
J Leukocyte Biol
, vol.81
, pp. 1213-1223
-
-
Blomgran, R.1
-
49
-
-
0023905240
-
Identification of latent procathepsins B and L in microsomal lumen: Characterization of enzymatic activation and proteolytic processing in vitro
-
Nishimura Y et al. Identification of latent procathepsins B and L in microsomal lumen: characterization of enzymatic activation and proteolytic processing in vitro. Arch Biochem Biophys 1988 61 : 64 71.
-
(1988)
Arch Biochem Biophys
, vol.61
, pp. 64-71
-
-
Nishimura, Y.1
-
50
-
-
0026664252
-
Rat procathepsin B. Proteolytic processing to the mature form in vitro
-
Rowan AD et al. Rat procathepsin B. Proteolytic processing to the mature form in vitro. J Biol Chem 1992 267 : 15993 15999.
-
(1992)
J Biol Chem
, vol.267
, pp. 15993-15999
-
-
Rowan, A.D.1
-
51
-
-
0035793580
-
Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route
-
Stoka V et al. Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route. J Biol Chem 2001 276 : 3149 3157.
-
(2001)
J Biol Chem
, vol.276
, pp. 3149-3157
-
-
Stoka, V.1
-
52
-
-
0030970351
-
Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity
-
Zhou Q, Salvesen GS. Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. Biochem J 1997 324 : 361 364.
-
(1997)
Biochem J
, vol.324
, pp. 361-364
-
-
Zhou, Q.1
Salvesen, G.S.2
-
53
-
-
0034485661
-
Cathepsin inhibition induces apoptotic death in human leukemia and lymphoma cells
-
Zhu DM, Uckun FM. Cathepsin inhibition induces apoptotic death in human leukemia and lymphoma cells. Leuk Lymphoma 2000 39 : 343 354.
-
(2000)
Leuk Lymphoma
, vol.39
, pp. 343-354
-
-
Zhu, D.M.1
Uckun, F.M.2
-
54
-
-
0025817602
-
The cystatins: Protein inhibitors of cysteine proteinases
-
Turk V, Bode W. The cystatins: protein inhibitors of cysteine proteinases. FEBS Lett 1991 285 : 213 219.
-
(1991)
FEBS Lett
, vol.285
, pp. 213-219
-
-
Turk, V.1
Bode, W.2
-
55
-
-
33751251999
-
Lysosomal destabilization contributes to apoptosis of germinal center B-lymphocytes
-
van Nierop K et al. Lysosomal destabilization contributes to apoptosis of germinal center B-lymphocytes. J Histochem Cytochem 2006 54 : 1425 1435.
-
(2006)
J Histochem Cytochem
, vol.54
, pp. 1425-1435
-
-
Van Nierop, K.1
-
56
-
-
0030918546
-
Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors
-
Turk B et al. Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors. Biol Chem 1997 378 : 141 150.
-
(1997)
Biol Chem
, vol.378
, pp. 141-150
-
-
Turk, B.1
-
57
-
-
0026570448
-
Interaction of recombinant human cystatin C with the cysteine proteinases papain and actinidin
-
Lindahl P et al. Interaction of recombinant human cystatin C with the cysteine proteinases papain and actinidin. Biochem J 1992 281 : 49 55.
-
(1992)
Biochem J
, vol.281
, pp. 49-55
-
-
Lindahl, P.1
-
58
-
-
15944426682
-
Inhibitory properties of cystatin F and its localization in U937 promonocyte cells
-
Langerholc T et al. Inhibitory properties of cystatin F and its localization in U937 promonocyte cells. FEBS J 2005 272 : 1535 1545.
-
(2005)
FEBS J
, vol.272
, pp. 1535-1545
-
-
Langerholc, T.1
-
59
-
-
0036077458
-
Cysteine peptidases of mammals: Their biological roles and potential effects in the oral cavity and other tissues in health and disease
-
Dickinson DP. Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease. Crit Rev Oral Biol Med 2002 13 : 238 275.
-
(2002)
Crit Rev Oral Biol Med
, vol.13
, pp. 238-275
-
-
Dickinson, D.P.1
-
60
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen GM. Caspases: the executioners of apoptosis. J Biochem 1997 326 : 1 16.
-
(1997)
J Biochem
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
61
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry NA, Lazebnik Y. Caspases: enemies within. Science 1998 281 : 1312 1316.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
62
-
-
0028168514
-
Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition
-
Komiyama T et al. Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition. J Biol Chem 1994 269 : 19331 19337.
-
(1994)
J Biol Chem
, vol.269
, pp. 19331-19337
-
-
Komiyama, T.1
-
63
-
-
0030810926
-
X-linked IAP is a direct inhibitor of cell-death proteases
-
Deveraux QL et al. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 1997 388 : 300 304.
-
(1997)
Nature
, vol.388
, pp. 300-304
-
-
Deveraux, Q.L.1
-
64
-
-
0030698127
-
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
-
Roy N et al. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J 1997 16 : 6914 6925.
-
(1997)
EMBO J
, vol.16
, pp. 6914-6925
-
-
Roy, N.1
-
65
-
-
0029056059
-
Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
-
Xue D, Horvitz HR. Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein. Nature 1995 377 : 248 251.
-
(1995)
Nature
, vol.377
, pp. 248-251
-
-
Xue, D.1
Horvitz, H.R.2
-
66
-
-
0028817947
-
Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35
-
Bump NJ et al. Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35. Science 1995 269 : 1885 1888.
-
(1995)
Science
, vol.269
, pp. 1885-1888
-
-
Bump, N.J.1
-
67
-
-
0033082995
-
IAP family proteins - Suppressors of apoptosis
-
Deveraux QL, Reed JC. IAP family proteins - suppressors of apoptosis. Genes Dev 1999 13 : 239 252.
-
(1999)
Genes Dev
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
68
-
-
0027990727
-
Control of programmed cell death by the baculovirus genes p35 and iap
-
Clem RJ, Miller LK. Control of programmed cell death by the baculovirus genes p35 and iap. Mol Cell Biol 1994 14 : 5212 5222.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5212-5222
-
-
Clem, R.J.1
Miller, L.K.2
-
69
-
-
0024413057
-
ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to Ubiquitin
-
Eytan E et al. ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to Ubiquitin. Proc Natl Acad Sci U S A 1989 86 : 7751 7755.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 7751-7755
-
-
Eytan, E.1
-
70
-
-
0027771443
-
Structural features of the 26 S proteasome complex
-
Peters JM et al. Structural features of the 26 S proteasome complex. J Mol Biol 1993 234 : 932 937.
-
(1993)
J Mol Biol
, vol.234
, pp. 932-937
-
-
Peters, J.M.1
-
71
-
-
0028234770
-
Distinct 19 S and 20 S subcomplexes of the 26 S proteasome and their distribution in the nucleus and the cytoplasm
-
Peters JM et al. Distinct 19 S and 20 S subcomplexes of the 26 S proteasome and their distribution in the nucleus and the cytoplasm. J Biol Chem 1994 269 : 7709 7718.
-
(1994)
J Biol Chem
, vol.269
, pp. 7709-7718
-
-
Peters, J.M.1
-
72
-
-
33745728140
-
Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132
-
Crawford LJ et al. Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132. Cancer Res 2006 66 : 6379 6386.
-
(2006)
Cancer Res
, vol.66
, pp. 6379-6386
-
-
Crawford, L.J.1
-
73
-
-
0030897031
-
Structure of 20S proteasome from yeast at 2.4 A resolution
-
Groll M et al. Structure of 20S proteasome from yeast at 2.4 A resolution. Nature 1997 386 : 463 471.
-
(1997)
Nature
, vol.386
, pp. 463-471
-
-
Groll, M.1
-
74
-
-
0030457014
-
Ubiquitin-dependent protein degradation
-
Hochstrasser M. Ubiquitin-dependent protein degradation. Ann Rev Genet 1996 30 : 405 439.
-
(1996)
Ann Rev Genet
, vol.30
, pp. 405-439
-
-
Hochstrasser, M.1
-
75
-
-
0030724422
-
Roles of ubiquitin-mediated proteolysis in cell cycle control
-
Hershko A. Roles of ubiquitin-mediated proteolysis in cell cycle control. Curr Opin Cell Biol 1997 9 : 788 799.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 788-799
-
-
Hershko, A.1
-
76
-
-
0030772933
-
Targeting of substrates to the 26S proteasome
-
Pickart CM. Targeting of substrates to the 26S proteasome. FASEB J 1997 11 : 1055 1066.
-
(1997)
FASEB J
, vol.11
, pp. 1055-1066
-
-
Pickart, C.M.1
-
77
-
-
0030016595
-
Structure and functions of the 20S and 26S proteasomes
-
Coux O et al. Structure and functions of the 20S and 26S proteasomes. Annu Rev Biochem 1996 65 : 801 847.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 801-847
-
-
Coux, O.1
-
79
-
-
0033563113
-
Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells
-
Zhang X-M et al. Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells. J Biochem 1999 340 : 127 133.
-
(1999)
J Biochem
, vol.340
, pp. 127-133
-
-
Zhang, X.-M.1
-
80
-
-
0025109563
-
Proteasomes are essential for yeast proliferation. cDNA cloning and gene disruption of two major subunits
-
Fujiwara T et al. Proteasomes are essential for yeast proliferation. cDNA cloning and gene disruption of two major subunits. J Biol Chem 1990 265 : 16604 16613.
-
(1990)
J Biol Chem
, vol.265
, pp. 16604-16613
-
-
Fujiwara, T.1
-
81
-
-
0029564960
-
Lactacystin, a specific inhibitor of the Proteasome, induces apoptosis in human monoblast U937 Cells
-
Imajoh-Ohmi S et al. Lactacystin, a specific inhibitor of the Proteasome, induces apoptosis in human monoblast U937 Cells. Biochem Biophys Res Commun 1995 217 : 1070 1077.
-
(1995)
Biochem Biophys Res Commun
, vol.217
, pp. 1070-1077
-
-
Imajoh-Ohmi, S.1
-
82
-
-
0029762871
-
Proteasomes play an essential role in thymocyte apoptosis
-
Grimm LM et al. Proteasomes play an essential role in thymocyte apoptosis. EMBO J 1996 15 : 3835 3844.
-
(1996)
EMBO J
, vol.15
, pp. 3835-3844
-
-
Grimm, L.M.1
-
83
-
-
0029033981
-
Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin
-
Fenteany G et al. Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science 1995 268 : 726 731.
-
(1995)
Science
, vol.268
, pp. 726-731
-
-
Fenteany, G.1
-
84
-
-
0036240701
-
The proteasome: A novel target for cancer chemotherapy
-
Almond JB, Cohen GM. The proteasome: a novel target for cancer chemotherapy. Leukemia 2002 16 : 433 443.
-
(2002)
Leukemia
, vol.16
, pp. 433-443
-
-
Almond, J.B.1
Cohen, G.M.2
-
85
-
-
0345447210
-
Velcade: U.S. FDA approval for the treatment of multiple myeloma progressing on prior therapy
-
Kane RC et al. Velcade: U.S. FDA approval for the treatment of multiple myeloma progressing on prior therapy. Oncologist 2003 8 : 508 513.
-
(2003)
Oncologist
, vol.8
, pp. 508-513
-
-
Kane, R.C.1
-
86
-
-
0032539571
-
Inhibitors of the chymotrypsin-like activity of proteasome based on di- and tri-peptidyl alpha-keto aldehydes (glyoxals)
-
Lynas JF et al. Inhibitors of the chymotrypsin-like activity of proteasome based on di- and tri-peptidyl alpha-keto aldehydes (glyoxals). Bioorg Med Chem Lett 1998 8 : 373 378.
-
(1998)
Bioorg Med Chem Lett
, vol.8
, pp. 373-378
-
-
Lynas, J.F.1
-
87
-
-
0027302689
-
Peptide glyoxals: A novel class of inhibitor for serine and cysteine proteinases
-
Walker B et al. Peptide glyoxals: a novel class of inhibitor for serine and cysteine proteinases. Biochem J 1993 293 : 321 323.
-
(1993)
Biochem J
, vol.293
, pp. 321-323
-
-
Walker, B.1
-
88
-
-
0033863365
-
Caspase and proteasome activity during staurosporine-induced apoptosis in lens epithelial cells
-
Andersson M et al. Caspase and proteasome activity during staurosporine-induced apoptosis in lens epithelial cells. Invest. Ophthalmol Vis Sci 2000 41 : 2623 2632.
-
(2000)
Invest. Ophthalmol Vis Sci
, vol.41
, pp. 2623-2632
-
-
Andersson, M.1
-
89
-
-
0023272405
-
Protection from tumor necrosis factor cytotoxicity by protease inhibitors
-
Ruggiero V et al. Protection from tumor necrosis factor cytotoxicity by protease inhibitors. Cell Immunol 1987 107 : 317 325.
-
(1987)
Cell Immunol
, vol.107
, pp. 317-325
-
-
Ruggiero, V.1
-
90
-
-
0028149332
-
Apoptotic cell death induced by intracellular proteolysis
-
Williams MS, Henkart PA. Apoptotic cell death induced by intracellular proteolysis. J Immunol 1994 153 : 4247 4255.
-
(1994)
J Immunol
, vol.153
, pp. 4247-4255
-
-
Williams, M.S.1
Henkart, P.A.2
-
91
-
-
0034194258
-
Serine protease inhibitors suppress cytochrome c-mediated caspase-9 activation and apoptosis during hypoxia-reoxygenation
-
Dong Z et al. Serine protease inhibitors suppress cytochrome c-mediated caspase-9 activation and apoptosis during hypoxia-reoxygenation. Biochem J 2000 347 : 669 677.
-
(2000)
Biochem J
, vol.347
, pp. 669-677
-
-
Dong, Z.1
-
92
-
-
33646826676
-
Caspase-dependant activation of chymotrypsin-like proteases mediates nuclear events during Jurkat T cell apoptosis
-
O'Connell AR et al. Caspase-dependant activation of chymotrypsin-like proteases mediates nuclear events during Jurkat T cell apoptosis. Biochem Biophys Res Commun 2006 345 : 608 616.
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 608-616
-
-
O'Connell, A.R.1
-
93
-
-
7944233607
-
Internucleosomal DNA cleavage in apoptotic WEHI 231 cells is mediated by a chymotrypsin-like protease
-
Murn J et al. Internucleosomal DNA cleavage in apoptotic WEHI 231 cells is mediated by a chymotrypsin-like protease. Genes Cells 2004 9 : 1103 1111.
-
(2004)
Genes Cells
, vol.9
, pp. 1103-1111
-
-
Murn, J.1
-
94
-
-
0035717034
-
A family of lymphocyte granule serine proteases
-
Trapani, Granzymes JA. a family of lymphocyte granule serine proteases. Genome Biol 2001 2 : 3014.1 3014.7.
-
(2001)
Genome Biol
, vol.2
, pp. 30141-30147
-
-
Trapani1
Granzymes, J.A.2
-
95
-
-
0035831462
-
Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition
-
Alimonti JB et al. Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition. J Biol Chem 2001 276 : 6974 6982.
-
(2001)
J Biol Chem
, vol.276
, pp. 6974-6982
-
-
Alimonti, J.B.1
-
96
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
Thornberry NA et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem 1997 272 : 17907 17911.
-
(1997)
J Biol Chem
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
-
97
-
-
0026353348
-
Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin in vitro
-
Pasternack MS et al. Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin in vitro. J Biol Chem 1991 266 : 14703 14708.
-
(1991)
J Biol Chem
, vol.266
, pp. 14703-14708
-
-
Pasternack, M.S.1
-
98
-
-
0028988261
-
Granzyme A is an interleukin 1 beta-converting enzyme
-
Irmler M et al. Granzyme A is an interleukin 1 beta-converting enzyme. J Exp Med 1995 181 : 1917 1922.
-
(1995)
J Exp Med
, vol.181
, pp. 1917-1922
-
-
Irmler, M.1
-
99
-
-
0024416820
-
Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A
-
Hayes MP et al. Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A. J Exp Med 1989 170 : 933 946.
-
(1989)
J Exp Med
, vol.170
, pp. 933-946
-
-
Hayes, M.P.1
-
100
-
-
0030777366
-
Activation of CPP32-like proteases is not sufficient to trigger apoptosis: Inhibition of apoptosis by agents that suppress activation of AP24, but not CPP32-like activity
-
Wright SC et al. Activation of CPP32-like proteases is not sufficient to trigger apoptosis: inhibition of apoptosis by agents that suppress activation of AP24, but not CPP32-like activity. J Exp Med 1997 186 : 1107 1117.
-
(1997)
J Exp Med
, vol.186
, pp. 1107-1117
-
-
Wright, S.C.1
-
101
-
-
18544386724
-
Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
-
Hegde R et al. Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction. J Biol Chem 2002 277 : 432 438.
-
(2002)
J Biol Chem
, vol.277
, pp. 432-438
-
-
Hegde, R.1
-
102
-
-
0033617146
-
A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein
-
Spiess C et al. A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein. Cell 1999 97 : 339 347.
-
(1999)
Cell
, vol.97
, pp. 339-347
-
-
Spiess, C.1
-
103
-
-
0344391918
-
HtrA2/Omi, a sheep in wolf's clothing
-
Vaux DL, Silke J. HtrA2/Omi, a sheep in wolf's clothing. Cell 2003 115 : 251 253.
-
(2003)
Cell
, vol.115
, pp. 251-253
-
-
Vaux, D.L.1
Silke, J.2
-
104
-
-
0034785591
-
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
Suzuki Y et al. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell 2001 8 : 613 621.
-
(2001)
Mol Cell
, vol.8
, pp. 613-621
-
-
Suzuki, Y.1
-
105
-
-
0037016686
-
HtrA2 promotes cell death through Its serine protease activity and its ability to antagonize Inhibitor of Apoptosis Proteins
-
Verhagen AM et al. HtrA2 promotes cell death through Its serine protease activity and its ability to antagonize Inhibitor of Apoptosis Proteins. J Biol Chem 2002 277 : 445 454.
-
(2002)
J Biol Chem
, vol.277
, pp. 445-454
-
-
Verhagen, A.M.1
-
106
-
-
0021100126
-
Tripeptidyl aminopeptidase in the extralysosomal fraction of rat liver
-
Balow RM et al. Tripeptidyl aminopeptidase in the extralysosomal fraction of rat liver. J Biol Chem 1983 258 : 11622 11628.
-
(1983)
J Biol Chem
, vol.258
, pp. 11622-11628
-
-
Balow, R.M.1
-
108
-
-
13344281002
-
Characterization and inhibition of a cholecystokinin-inactivating serine peptidase
-
DOI 10.1038/380403a0
-
Rose C et al. Characterization and inhibition of a cholecystokinin- inactivating serine peptidase. Nature 1996 380 : 403 409. (Pubitemid 26102716)
-
(1996)
Nature
, vol.380
, Issue.6573
, pp. 403-409
-
-
Rose, C.1
Vargas, F.2
Facchinetti, P.3
Bourgeat, P.4
Bambal, R.B.5
Bishop, P.B.6
Chan, S.M.T.7
Moore, A.N.J.8
Ganellin, C.R.9
Schwartz, J.-C.10
-
109
-
-
0033548055
-
A giant protease with potential to substitute for some functions of the proteasome
-
Geier E et al. A giant protease with potential to substitute for some functions of the proteasome. Science 1999 283 : 978 981.
-
(1999)
Science
, vol.283
, pp. 978-981
-
-
Geier, E.1
-
110
-
-
0023229578
-
Supramolecular structure of tripeptidyl peptidase II from human erythrocytes as studied by electron microscopy, and its correlation to enzyme activity
-
Macpherson E et al. Supramolecular structure of tripeptidyl peptidase II from human erythrocytes as studied by electron microscopy, and its correlation to enzyme activity. Biochem J 1987 248 : 259 263.
-
(1987)
Biochem J
, vol.248
, pp. 259-263
-
-
MacPherson, E.1
-
111
-
-
77952757807
-
Tripeptidyl-peptidase II
-
2nd edn. Barrett, A.J.*et al. eds.
-
Tomkinson, B. Tripeptidyl-peptidase II. In : Barrett AJ et al., eds. Handbook of Proteolytic Enzymes, 2nd edn.
-
Handbook of Proteolytic Enzymes
-
-
Tomkinson, B.1
-
112
-
-
0035097842
-
C-myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells
-
Gavioli R et al. c-myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells. Nat Cell Biol 2001 3 : 283 288.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 283-288
-
-
Gavioli, R.1
-
113
-
-
0036036450
-
Tripeptidyl-peptidase II expression and activity are increased in skeletal muscle during sepsis
-
Wray CJ et al. Tripeptidyl-peptidase II expression and activity are increased in skeletal muscle during sepsis. Biochem Biophys Res Commun 2002 296 : 41 47.
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 41-47
-
-
Wray, C.J.1
-
114
-
-
0036295676
-
Molecular regulation of muscle cachexia: It may be more than the proteasome
-
Hasselgren PO et al. Molecular regulation of muscle cachexia: it may be more than the proteasome. Biochem Biophys Res Commun 2002 290 : 1 10.
-
(2002)
Biochem Biophys Res Commun
, vol.290
, pp. 1-10
-
-
Hasselgren, P.O.1
-
115
-
-
12844268167
-
Effect of cancer cachexia on the activity of tripeptidyl-peptidase II in skeletal muscle
-
Chand A et al. Effect of cancer cachexia on the activity of tripeptidyl-peptidase II in skeletal muscle. Cancer Lett 2005 218 : 215 222.
-
(2005)
Cancer Lett
, vol.218
, pp. 215-222
-
-
Chand, A.1
-
116
-
-
0033796540
-
Tripeptidyl Peptidase II promotes maturation of caspase-1 in Shigella flexneri-induced macrophage apoptosis
-
Hilbi H et al. Tripeptidyl Peptidase II promotes maturation of caspase-1 in Shigella flexneri-induced macrophage apoptosis. Infect Immun 2000 68 : 5502 5508.
-
(2000)
Infect Immun
, vol.68
, pp. 5502-5508
-
-
Hilbi, H.1
-
117
-
-
0037529368
-
Tumors acquire inhibitor of apoptosis protein (IAP)-mediated apoptosis resistance through altered specificity of cytosolic proteolysis
-
Hong X et al. Tumors acquire inhibitor of apoptosis protein (IAP)-mediated apoptosis resistance through altered specificity of cytosolic proteolysis. J Exp Med 2003 197 : 1731 1743.
-
(2003)
J Exp Med
, vol.197
, pp. 1731-1743
-
-
Hong, X.1
-
118
-
-
1842785206
-
A major role for TPPII in trimming proteasomal degradation products for MHC Class i antigen presentation
-
Reits E et al. A major role for TPPII in trimming proteasomal degradation products for MHC Class I antigen presentation. Immunity 2004 20 : 495 506.
-
(2004)
Immunity
, vol.20
, pp. 495-506
-
-
Reits, E.1
-
119
-
-
33746215297
-
Tripeptidyl peptidase II is the major peptidase needed to trim long antigenic precursors, but is not required for most MHC class i antigen presentation
-
York IA et al. Tripeptidyl peptidase II is the major peptidase needed to trim long antigenic precursors, but is not required for most MHC class I antigen presentation. J Immunol 2006 177 : 1434 1443.
-
(2006)
J Immunol
, vol.177
, pp. 1434-1443
-
-
York, I.A.1
-
120
-
-
10744230904
-
AAF-cmk sensitizes tumor cells to trail-mediated apoptosis
-
Mllnarczuk I et al. AAF-cmk sensitizes tumor cells to trail-mediated apoptosis. Leuk Res 2004 28 : 53 61.
-
(2004)
Leuk Res
, vol.28
, pp. 53-61
-
-
Mllnarczuk, I.1
-
121
-
-
0036957579
-
Serine protease inhibitor Spi2 mediated apoptosis of olfactory neurons
-
Thiemmara V et al. Serine protease inhibitor Spi2 mediated apoptosis of olfactory neurons. Cell Death Differ 2002 9 : 1343 1351.
-
(2002)
Cell Death Differ
, vol.9
, pp. 1343-1351
-
-
Thiemmara, V.1
-
122
-
-
0014423833
-
Chemical modification of papain. I. Reaction with the chloromethyl ketones of phenylalanine and lysine and with phenylmethylsulfonyl fluoride
-
Whitaker JR, Perez-Villasenor J. Chemical modification of papain. I. Reaction with the chloromethyl ketones of phenylalanine and lysine and with phenylmethylsulfonyl fluoride. Arch Biochem Biophys 1968 124 : 70 78.
-
(1968)
Arch Biochem Biophys
, vol.124
, pp. 70-78
-
-
Whitaker, J.R.1
Perez-Villasenor, J.2
-
123
-
-
0014766277
-
Selective chemical modification of proteins
-
Shaw E. Selective chemical modification of proteins. Physiol Rev 1970 50 : 244 296.
-
(1970)
Physiol Rev
, vol.50
, pp. 244-296
-
-
Shaw, E.1
-
124
-
-
0033570275
-
Crystal structure of gingipain R: An Arg-specific bacterial cysteine proteinase with a caspase-like fold
-
Eichinger A et al. Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold. EMBO J 1999 18 : 5453 5462.
-
(1999)
EMBO J
, vol.18
, pp. 5453-5462
-
-
Eichinger, A.1
-
125
-
-
12444315984
-
Inhibition of papain-like cysteine proteases and legumain by "caspase-specific" inhibitors: When reaction mechanism is more important than specificity
-
Rozman-Pungerčar J et al. Inhibition of papain-like cysteine proteases and legumain by "caspase-specific" inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ 2003 10 : 881 888.
-
(2003)
Cell Death Differ
, vol.10
, pp. 881-888
-
-
Rozman-Pungerčar, J.1
-
126
-
-
0016152114
-
Inhibition of macromolecular synthesis in Escherichia coli by protease inhibitors. Specific reversal by glutathione of the effects of chloromethyl ketones
-
Rossman T et al. Inhibition of macromolecular synthesis in Escherichia coli by protease inhibitors. Specific reversal by glutathione of the effects of chloromethyl ketones. J Biol Chem 1974 249 : 3412 3417.
-
(1974)
J Biol Chem
, vol.249
, pp. 3412-3417
-
-
Rossman, T.1
-
127
-
-
0020641260
-
Inhibition of neutrophil sulfhydryl groups by chloromethyl ketones. A mechanism for their inhibition of superoxide production
-
Tsan MF. Inhibition of neutrophil sulfhydryl groups by chloromethyl ketones. A mechanism for their inhibition of superoxide production. Biochem Biophys Res Commun 1983 112 : 671 677.
-
(1983)
Biochem Biophys Res Commun
, vol.112
, pp. 671-677
-
-
Tsan, M.F.1
-
128
-
-
0000700968
-
Evidence for an active-center histidine in trypsin through use of a specific reagent, 1-chloro-3-tosylamido-7-amino-2-heptanone, the chloromethyl ketone derived from Nα-tosyl-L-lysine
-
Shaw E et al. Evidence for an active-center histidine in trypsin through use of a specific reagent, 1-chloro-3-tosylamido-7-amino-2-heptanone, the chloromethyl ketone derived from Nα-tosyl-L-lysine. Biochemistry 1965 4 : 2219 2224.
-
(1965)
Biochemistry
, vol.4
, pp. 2219-2224
-
-
Shaw, E.1
-
129
-
-
0015950980
-
Affinity labelling of proteinases with tryptic specificity by peptides with C-terminal lysine chloromethyl ketone
-
Coggins JR et al. Affinity labelling of proteinases with tryptic specificity by peptides with C-terminal lysine chloromethyl ketone. Biochem J 1974 137 : 579 585.
-
(1974)
Biochem J
, vol.137
, pp. 579-585
-
-
Coggins, J.R.1
-
130
-
-
0001244705
-
Direct evidence for the presence of histidine in the active center of chymotrypsin
-
Schoellmann G, Shaw E. Direct evidence for the presence of histidine in the active center of chymotrypsin. Biochemistry 1963 2 : 252 255.
-
(1963)
Biochemistry
, vol.2
, pp. 252-255
-
-
Schoellmann, G.1
Shaw, E.2
-
131
-
-
15944363451
-
Another biological effect of tosylphenylalanylchloromethane (TPCK): It prevents p47phox phosphorylation and translocation upon neutrophil stimulation
-
Gillibert M et al. Another biological effect of tosylphenylalanylchloromethane (TPCK): it prevents p47phox phosphorylation and translocation upon neutrophil stimulation. Biochem J 2005 386 : 549 556.
-
(2005)
Biochem J
, vol.386
, pp. 549-556
-
-
Gillibert, M.1
-
132
-
-
17144378200
-
Pro- and anti-apoptotic effects of an inhibitor of chymotrypsin-like serine proteases
-
King MA et al. Pro- and anti-apoptotic effects of an inhibitor of chymotrypsin-like serine proteases. Cell Cycle 2004 3 : 1566 1571.
-
(2004)
Cell Cycle
, vol.3
, pp. 1566-1571
-
-
King, M.A.1
-
133
-
-
0027255417
-
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
-
Kaufmann SH et al. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res 1993 53 : 3976 3985.
-
(1993)
Cancer Res
, vol.53
, pp. 3976-3985
-
-
Kaufmann, S.H.1
-
134
-
-
0022246323
-
N-alpha-Tosyl-L-lysine chloromethyl ketone and N-alpha-tosyl-L- phenylalanine chloromethyl ketone inhibit protein kinase C
-
Solomon DH et al. N-alpha-Tosyl-L-lysine chloromethyl ketone and N-alpha-tosyl-L-phenylalanine chloromethyl ketone inhibit protein kinase C. FEBS Lett 1985 190 : 342 344.
-
(1985)
FEBS Lett
, vol.190
, pp. 342-344
-
-
Solomon, D.H.1
-
135
-
-
0020491337
-
Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties
-
Kikkawa U et al. Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties. J Biol Chem 1982 257 : 13341 13348.
-
(1982)
J Biol Chem
, vol.257
, pp. 13341-13348
-
-
Kikkawa, U.1
-
136
-
-
20844442967
-
Can application of serine protease inhibitors TPCK and TLCK provide evidence for possible involvement of serine protease Omi/HtrA2 in imatinib mesylate-induced cell death of BCR-ABL-positive human leukemia cells
-
Mlejnek P. Can application of serine protease inhibitors TPCK and TLCK provide evidence for possible involvement of serine protease Omi/HtrA2 in imatinib mesylate-induced cell death of BCR-ABL-positive human leukemia cells Leukemia 2005 19 : 1085 1087.
-
(2005)
Leukemia
, vol.19
, pp. 1085-1087
-
-
Mlejnek, P.1
-
137
-
-
0028172869
-
Inducible phosphorylation of i kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors
-
Finco TS et al. Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors. Proc Natl Acad Sci U S A 1994 91 : 11884 11888.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 11884-11888
-
-
Finco, T.S.1
-
138
-
-
0029091469
-
Protease inhibitors differentially regulate tumor necrosis factor-induced apoptosis, nuclear factor-kappa B activation, cytotoxicity, and differentiation
-
Higuchi M et al. Protease inhibitors differentially regulate tumor necrosis factor-induced apoptosis, nuclear factor-kappa B activation, cytotoxicity, and differentiation. Blood 1995 86 : 2248 2256.
-
(1995)
Blood
, vol.86
, pp. 2248-2256
-
-
Higuchi, M.1
-
140
-
-
0028557348
-
Tumor necrosis factor alpha-induced phosphorylation of i kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B
-
Miyamoto S et al. Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B. Proc Natl Acad Sci U S A 1994 91 : 12740 12744.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 12740-12744
-
-
Miyamoto, S.1
-
141
-
-
0028981050
-
Activation of NF-kappa B requires proteolysis of the inhibitor i kappa B-alpha: Signal-induced phosphorylation of i kappa B-alpha alone does not release active NF-kappa B
-
Lin Y et al. Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B. Proc Natl Acad Sci U S A 1995 92 : 552 556.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 552-556
-
-
Lin, Y.1
-
142
-
-
0028985190
-
Phosphorylation of i kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B
-
DiDonato JA et al. Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B. Mol Cell Biol 1995 15 : 1302 1311.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1302-1311
-
-
Didonato, J.A.1
-
143
-
-
0027367970
-
Purification and characterization of a tripeptidyl peptidase i from human osteoclastomas: Evidence for its role in bone resorption
-
Page AE et al. Purification and characterization of a tripeptidyl peptidase I from human osteoclastomas: evidence for its role in bone resorption. Arch Biochem Biophys 1993 306 : 354 359.
-
(1993)
Arch Biochem Biophys
, vol.306
, pp. 354-359
-
-
Page, A.E.1
-
144
-
-
0025979246
-
Irreversible inhibition of serine proteases by peptide derivatives of (alpha-aminoalkyl)phosphonate diphenyl esters
-
Oleksyszyn J, Powers JC. Irreversible inhibition of serine proteases by peptide derivatives of (alpha-aminoalkyl)phosphonate diphenyl esters. Biochemistry 1991 30 : 485 493.
-
(1991)
Biochemistry
, vol.30
, pp. 485-493
-
-
Oleksyszyn, J.1
Powers, J.C.2
-
145
-
-
0028057482
-
Novel amidine-containing peptidyl phosphonates as irreversible inhibitors for blood coagulation and related serine proteases
-
Oleksyszyn J et al. Novel amidine-containing peptidyl phosphonates as irreversible inhibitors for blood coagulation and related serine proteases. J Med Chem 1994 37 : 226 231.
-
(1994)
J Med Chem
, vol.37
, pp. 226-231
-
-
Oleksyszyn, J.1
-
146
-
-
0033602521
-
Structure-activity relationship of diaryl phosphonate esters as potent irreversible dipeptidyl peptidase IV inhibitors
-
Belyaev A et al. Structure-activity relationship of diaryl phosphonate esters as potent irreversible dipeptidyl peptidase IV inhibitors. J Med Chem 1999 42 : 1041 1052.
-
(1999)
J Med Chem
, vol.42
, pp. 1041-1052
-
-
Belyaev, A.1
-
147
-
-
0028672813
-
Amino acid and peptide phosphonate derivatives as specific inhibitors of serine peptidases
-
Oleksyszyn J, Powers JC. Amino acid and peptide phosphonate derivatives as specific inhibitors of serine peptidases. Methods Enzymol 1994 244 : 423 441.
-
(1994)
Methods Enzymol
, vol.244
, pp. 423-441
-
-
Oleksyszyn, J.1
Powers, J.C.2
-
148
-
-
0030612395
-
In vivo inhibition of dipeptide peptidase IV activity by Pro-Pro-diphenyl-phosphonate (prodipine)
-
DOI 10.1016/S0006-2952(97)00149-4, PII S0006295297001494
-
De Meester I et al. In vivo inhibition of dipeptidyl peptidase IV activity by Pro-Pro-diphenyl-phosphonate (Prodipine). Biochem Pharmacol 1997 54 : 173 179. (Pubitemid 27353235)
-
(1997)
Biochemical Pharmacology
, vol.54
, Issue.1
, pp. 173-179
-
-
De Meester, I.1
Belyaev, A.2
Lambeir, A.-M.3
De Meyer, G.R.Y.4
Van Osselaer, N.5
Haemers, A.6
Scharpe, S.7
|