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Volumn 15, Issue 15, 1996, Pages 3861-3870

Cathepsin D protease mediates programmed cell death induced by interferon-γ, Fas/APO-1 and TNF-α

Author keywords

Cathepsin D; Cell death; Fas; Interferon ; TNF

Indexed keywords

CATHEPSIN D; COMPLEMENTARY DNA; COMPLEMENTARY RNA; FAS ANTIGEN; GAMMA INTERFERON; PEPSTATIN; PROTEINASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0029782494     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00760.x     Document Type: Article
Times cited : (425)

References (51)
  • 1
    • 0028913550 scopus 로고
    • A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
    • Boldin, M.P., Varfolomeev, E.E., Pancer, Z., Mett, L., Camonis, J.H. and Wallach, D. (1995) A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain. J. Biol. Chem., 270, 7795-7798.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7795-7798
    • Boldin, M.P.1    Varfolomeev, E.E.2    Pancer, Z.3    Mett, L.4    Camonis, J.H.5    Wallach, D.6
  • 2
    • 0029026548 scopus 로고
    • FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnalyan, A.M., O'Rourke, K., Tewari, M. and Dixit, V.M. (1995) FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell, 81, 505-512.
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnalyan, A.M.1    O'Rourke, K.2    Tewari, M.3    Dixit, V.M.4
  • 3
    • 0025736597 scopus 로고
    • A genetic tool used to identify thioredoxin as a mediator of a growth inhibitory signal
    • Deiss, L.P. and Kimchi, A. (1991) A genetic tool used to identify thioredoxin as a mediator of a growth inhibitory signal. Science, 252, 117-120.
    • (1991) Science , vol.252 , pp. 117-120
    • Deiss, L.P.1    Kimchi, A.2
  • 4
    • 0028831202 scopus 로고
    • Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of gamma interferon-induced cell death
    • Deiss, L.P., Feinstein, E., Berissi, H., Cohen, O. and Kimchi, A. (1995) Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of gamma interferon-induced cell death. Genes Dev., 9, 15-30.
    • (1995) Genes Dev. , vol.9 , pp. 15-30
    • Deiss, L.P.1    Feinstein, E.2    Berissi, H.3    Cohen, O.4    Kimchi, A.5
  • 5
    • 0024382416 scopus 로고
    • Cleavage of parathyroid hormone in macrophage endosomes illustrates a novel pathway for intracellular processing of proteins
    • Diment, S., Martin, K.J. and Stahl, P.D. (1989) Cleavage of parathyroid hormone in macrophage endosomes illustrates a novel pathway for intracellular processing of proteins. J. Biol. Chem., 264, 13403-13416.
    • (1989) J. Biol. Chem. , vol.264 , pp. 13403-13416
    • Diment, S.1    Martin, K.J.2    Stahl, P.D.3
  • 6
    • 0027253573 scopus 로고
    • Dicistronic transcription units for gene expression in mammalian cells
    • Dirks, W., Wirth, M. and Hauser, H. (1993) Dicistronic transcription units for gene expression in mammalian cells. Gene, 128, 247-259.
    • (1993) Gene , vol.128 , pp. 247-259
    • Dirks, W.1    Wirth, M.2    Hauser, H.3
  • 8
    • 0029022365 scopus 로고
    • Involvement of an ICE-like protease in Fas-mediated apoptosis
    • Enari, M., Hug, H. and Nagata, S. (1995) Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature, 375, 78-81.
    • (1995) Nature , vol.375 , pp. 78-81
    • Enari, M.1    Hug, H.2    Nagata, S.3
  • 10
    • 0029005646 scopus 로고
    • A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells
    • Faucheu, C. et al. (1995) A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells. EMBO J., 14, 1914-1922.
    • (1995) EMBO J. , vol.14 , pp. 1914-1922
    • Faucheu, C.1
  • 11
    • 0011288815 scopus 로고
    • Cloning and sequence analysis of cDNA for human cathepsin D
    • Faust, P.L., Kornfeld, S. and Chirgwin, J.M (1985) Cloning and sequence analysis of cDNA for human cathepsin D. Proc. Natl Acad. Sci. USA, 82, 4910-4914.
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 4910-4914
    • Faust, P.L.1    Kornfeld, S.2    Chirgwin, J.M.3
  • 12
  • 13
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegant cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme
    • Fernandes, A.T., Litwack, G. and Alnemri, E.S. (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegant cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J. Biol. Chem., 269, 30761-30764.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30761-30764
    • Fernandes, A.T.1    Litwack, G.2    Alnemri, E.S.3
  • 14
    • 0029025549 scopus 로고
    • Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family
    • Fernandes, A.T., Litwack, J. and Alnemri, E.S. (1995) Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res., 55, 2737-2742.
    • (1995) Cancer Res. , vol.55 , pp. 2737-2742
    • Fernandes, A.T.1    Litwack, J.2    Alnemri, E.S.3
  • 15
    • 0025950610 scopus 로고
    • Isolation and sequencing of a cDNA clone encoding rat liver lysosomal cathepsin D and the structure of three forms of mature enzymes
    • Fujita, H., Tanaka, Y., Noguchi, Y., Kono, A., Himeno, M. and Kato, K. (1991) Isolation and sequencing of a cDNA clone encoding rat liver lysosomal cathepsin D and the structure of three forms of mature enzymes. Biochem. Biophys. Res. Commun., 179, 190-196.
    • (1991) Biochem. Biophys. Res. Commun. , vol.179 , pp. 190-196
    • Fujita, H.1    Tanaka, Y.2    Noguchi, Y.3    Kono, A.4    Himeno, M.5    Kato, K.6
  • 16
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen, M. and Bujard, H. (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl Acad. Sci. USA, 89, 5547-5551.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 17
    • 0029161958 scopus 로고
    • The head involution defective gene of Drosophila melanogaster functions in programmed cell death
    • Grether, M.E., Abrams, J.M., Agapite, J., White, K. and Steller, H. (1995) The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev., 9, 1694-1708.
    • (1995) Genes Dev. , vol.9 , pp. 1694-1708
    • Grether, M.E.1    Abrams, J.M.2    Agapite, J.3    White, K.4    Steller, H.5
  • 18
    • 0029007855 scopus 로고
    • The TNFreceptor 1-associated protein TRADD signals cell death and NF-κB activation
    • Heu, H., Xiong, J. and Goeddel, D.V. (1995) The TNFreceptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell, 81, 495-504.
    • (1995) Cell , vol.81 , pp. 495-504
    • Heu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 19
    • 0028258577 scopus 로고
    • Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
    • Heusel, J.W., Wesselschmidt, R.L., Shresta, S., Russell, J.H. and Ley, T.J. (1994) Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell, 76, 977-987.
    • (1994) Cell , vol.76 , pp. 977-987
    • Heusel, J.W.1    Wesselschmidt, R.L.2    Shresta, S.3    Russell, J.H.4    Ley, T.J.5
  • 21
    • 0026072245 scopus 로고
    • Proteolysis of microtubule-associated protein 2 and tubulin by cathepsin D
    • Johnson, G.V., Litersky, J.M. and Whitaker, J.N. (1991) Proteolysis of microtubule-associated protein 2 and tubulin by cathepsin D. J. Neurochem., 57, 1577-1583.
    • (1991) J. Neurochem. , vol.57 , pp. 1577-1583
    • Johnson, G.V.1    Litersky, J.M.2    Whitaker, J.N.3
  • 22
  • 23
    • 0026646066 scopus 로고
    • Cytokine triggered molecular pathways that control cell cycle arrest
    • Kimchi, A. (1992) Cytokine triggered molecular pathways that control cell cycle arrest. J. Cell Biochem., 50, 1-9
    • (1992) J. Cell Biochem. , vol.50 , pp. 1-9
    • Kimchi, A.1
  • 24
  • 25
    • 0027990778 scopus 로고
    • Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme
    • Kumar, S., Kinoshita, M., Noda, M., Copeland, N.G. and Jenkins, N.A. (1994) Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme. Genes Dev., 8, 1613-1626.
    • (1994) Genes Dev. , vol.8 , pp. 1613-1626
    • Kumar, S.1    Kinoshita, M.2    Noda, M.3    Copeland, N.G.4    Jenkins, N.A.5
  • 26
    • 0023697978 scopus 로고
    • Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis
    • Laster, S.M., Wood, J.G. and Gooding, L.R. (1988) Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis. J. Immunol., 141, 2629-2634.
    • (1988) J. Immunol. , vol.141 , pp. 2629-2634
    • Laster, S.M.1    Wood, J.G.2    Gooding, L.R.3
  • 27
    • 0026584374 scopus 로고
    • In vitro apoptosis in the hepatoma cell line induced by transforming growth factor-beta
    • Lin, J.K. and Chou, C.K. (1992) In vitro apoptosis in the hepatoma cell line induced by transforming growth factor-beta. Cancer Res., 52, 385-388.
    • (1992) Cancer Res. , vol.52 , pp. 385-388
    • Lin, J.K.1    Chou, C.K.2
  • 28
    • 0029005805 scopus 로고
    • Requirement of an ICE/CED-3 protease for Fas/ APO-1-mediated apoptosis
    • Los, M. et al. (1995) Requirement of an ICE/CED-3 protease for Fas/ APO-1-mediated apoptosis. Nature, 375, 81-83.
    • (1995) Nature , vol.375 , pp. 81-83
    • Los, M.1
  • 29
    • 0023544344 scopus 로고
    • Age-related increase in a cathepsin D like protease that degrades brain microtubule-associated proteins
    • Matus, A. and Green, G.D. (1987) Age-related increase in a cathepsin D like protease that degrades brain microtubule-associated proteins. Biochemistry, 26, 8083-8086.
    • (1987) Biochemistry , vol.26 , pp. 8083-8086
    • Matus, A.1    Green, G.D.2
  • 30
    • 0027535914 scopus 로고
    • Biology and biochemistry of proteinases in tumor invasion
    • Mignatti, P. and Rifkin, D.B. (1993) Biology and biochemistry of proteinases in tumor invasion. Physiol. Rev., 73, 161-195.
    • (1993) Physiol. Rev. , vol.73 , pp. 161-195
    • Mignatti, P.1    Rifkin, D.B.2
  • 31
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
    • Miura, M., Zhu, H., Rotello, R., Hartwieg, E.A. and Yuan, J. (1993) Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell, 75, 653-660.
    • (1993) Cell , vol.75 , pp. 653-660
    • Miura, M.1    Zhu, H.2    Rotello, R.3    Hartwieg, E.A.4    Yuan, J.5
  • 32
    • 0028205312 scopus 로고
    • Environmental signals influencing expression of the IFN-gamma receptor on human T cells control whether IFN-gamma promotes proliferation or apoptosis
    • Novelli, F., Di Pierro, F., Francia di Celle, P., Bertini, S., Affaticati, P., Garotta, G. and Forni, G. (1994) Environmental signals influencing expression of the IFN-gamma receptor on human T cells control whether IFN-gamma promotes proliferation or apoptosis. J. Immunol., 152, 496-504.
    • (1994) J. Immunol. , vol.152 , pp. 496-504
    • Novelli, F.1    Di Pierro, F.2    Francia Di Celle, P.3    Bertini, S.4    Affaticati, P.5    Garotta, G.6    Forni, G.7
  • 33
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • Raff, M.C. (1992) Social controls on cell survival and cell death. Nature, 356, 397-400.
    • (1992) Nature , vol.356 , pp. 397-400
    • Raff, M.C.1
  • 34
    • 0029083689 scopus 로고
    • Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells
    • Saftig, P., Hetman, M., Schmahl, W., Weber, K., Heine, L. and Peters, C. (1995) Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells. EMBO J., 14, 3599-3608.
    • (1995) EMBO J. , vol.14 , pp. 3599-3608
    • Saftig, P.1    Hetman, M.2    Schmahl, W.3    Weber, K.4    Heine, L.5    Peters, C.6
  • 35
    • 43949164912 scopus 로고
    • Programmed cell death, apoptosis and killer genes
    • Schwartz, L.M. and Osborne, B.A. (1993) Programmed cell death, apoptosis and killer genes. Immunol. Today, 14, 582-590.
    • (1993) Immunol. Today , vol.14 , pp. 582-590
    • Schwartz, L.M.1    Osborne, B.A.2
  • 36
    • 0025788642 scopus 로고
    • Accumulation of pepstatin in cultured endothelial cells and its effect on endothelial processing
    • Shields, P.P., Gonzales, T.A., Charles, D., Gilligan, J.P. and Stern, W. (1991) Accumulation of pepstatin in cultured endothelial cells and its effect on endothelial processing. Biochem. Biophys. Res. Commun., 177, 1006-1012.
    • (1991) Biochem. Biophys. Res. Commun. , vol.177 , pp. 1006-1012
    • Shields, P.P.1    Gonzales, T.A.2    Charles, D.3    Gilligan, J.P.4    Stern, W.5
  • 37
    • 0029054725 scopus 로고
    • RIP: A novel protein containing a death domain that interacts with Fas/ APO-1 (CD95) in yeast and causes cell death
    • Stanger, B.Z., Leder, P., Lee, T.H., Kim, E. and Seed, B. (1995) RIP: a novel protein containing a death domain that interacts with Fas/ APO-1 (CD95) in yeast and causes cell death. Cell, 81, 513-523.
    • (1995) Cell , vol.81 , pp. 513-523
    • Stanger, B.Z.1    Leder, P.2    Lee, T.H.3    Kim, E.4    Seed, B.5
  • 38
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller, H. (1995) Mechanisms and genes of cellular suicide. Science, 267, 1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 39
    • 0028097822 scopus 로고
    • Purification and characterization of the Fas-ligand that induces apoptosis
    • Suda, T. and Nagata, S. (1994) Purification and characterization of the Fas-ligand that induces apoptosis. J. Exp. Med., 179, 873-879.
    • (1994) J. Exp. Med. , vol.179 , pp. 873-879
    • Suda, T.1    Nagata, S.2
  • 40
    • 0028873964 scopus 로고
    • Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product
    • Tewari, M. and Dixit, V.M. (1995) Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product. J. Biol. Chem., 270, 3255-3260.
    • (1995) J. Biol. Chem. , vol.270 , pp. 3255-3260
    • Tewari, M.1    Dixit, V.M.2
  • 41
    • 0028990125 scopus 로고
    • Yama/ CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
    • Tewari, M., Quan, L.T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D.R., Poirier, G.G., Salvesen, G.S. and Dixit, V.M. (1995) Yama/ CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell, 81, 1-20
    • (1995) Cell , vol.81 , pp. 1-20
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Salvesen, G.S.8    Dixit, V.M.9
  • 43
    • 0021321027 scopus 로고
    • Preparations of lymphotoxin induce resistance to their own cytotoxic effect
    • Wallach, D. (1984) Preparations of lymphotoxin induce resistance to their own cytotoxic effect. J. Immunol., 132, 2464-2469.
    • (1984) J. Immunol. , vol.132 , pp. 2464-2469
    • Wallach, D.1
  • 44
    • 0028168593 scopus 로고
    • Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death
    • Wang, L., Miura, M., Bergeron, L., Zhu, H. and Yuan, J. (1994) Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell, 78, 739-750.
    • (1994) Cell , vol.78 , pp. 739-750
    • Wang, L.1    Miura, M.2    Bergeron, L.3    Zhu, H.4    Yuan, J.5
  • 46
    • 0026600008 scopus 로고
    • Apoptosis and DNA fragmentation precede TNF-induced cytolysis in U937 cells
    • Wright, S.C., Kumar, P., Tam, A.W., Shen, N., Varma, M. and Larrick, J.W. (1992) Apoptosis and DNA fragmentation precede TNF-induced cytolysis in U937 cells. J. Cell Biochem., 48, 344-355.
    • (1992) J. Cell Biochem. , vol.48 , pp. 344-355
    • Wright, S.C.1    Kumar, P.2    Tam, A.W.3    Shen, N.4    Varma, M.5    Larrick, J.W.6
  • 47
    • 0028939862 scopus 로고
    • The genetic regulation of apoptosis
    • Wyllie, A.H. (1995) The genetic regulation of apoptosis. Curr. Opin. Genet. Dev., 5, 97-104.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 97-104
    • Wyllie, A.H.1
  • 48
    • 0022993665 scopus 로고
    • Tumor necrosis factor reduces c-myc expression and cooperates with interferon-gamma in HeLa cells
    • Yarden, A. and Kimchi, A. (1986) Tumor necrosis factor reduces c-myc expression and cooperates with interferon-gamma in HeLa cells. Science, 234, 1419-1421.
    • (1986) Science , vol.234 , pp. 1419-1421
    • Yarden, A.1    Kimchi, A.2
  • 49
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach, E., Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A. and Oren, M. (1991) Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature, 352, 345-347.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 50
    • 0026448963 scopus 로고
    • The C. elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death
    • Yuan, J. and Horvitz, H.R. (1992) The C. elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death. Development, 116, 309-320.
    • (1992) Development , vol.116 , pp. 309-320
    • Yuan, J.1    Horvitz, H.R.2
  • 51
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
    • Yuan, J., Shaham, S., Ledoux, S., Ellis, H.M. and Horvitz, H.R. (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell, 75, 641-752.
    • (1993) Cell , vol.75 , pp. 641-752
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5


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