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Volumn 14, Issue 6, 1996, Pages 642-650

Biological and clinical significance of cathepsin D in breast cancer metastasis

Author keywords

Breast cancer; Cathepsin D; Growth inhibitors; Metastasis; Phagocytosis; Prognosis

Indexed keywords

CATHEPSIN D; ESTROGEN; ESTROGEN RECEPTOR; GROWTH FACTOR; PROTEIN PRECURSOR;

EID: 0029838059     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.140642     Document Type: Review
Times cited : (137)

References (63)
  • 1
    • 0014774690 scopus 로고
    • Cathepsin D: Purification of isoenzymes from human and chicken liver
    • Barrett AJ. Cathepsin D: purification of isoenzymes from human and chicken liver. Biochem J 1970;117:601-607.
    • (1970) Biochem J , vol.117 , pp. 601-607
    • Barrett, A.J.1
  • 2
    • 0024412693 scopus 로고
    • The selectivity of cathepsin D suggests an involvement of the enzyme in the generation of T-cell epitopes
    • Van Noort JM, Van der Drift AC. The selectivity of cathepsin D suggests an involvement of the enzyme in the generation of T-cell epitopes. J Biol Chem 1989;264:14159-14164.
    • (1989) J Biol Chem , vol.264 , pp. 14159-14164
    • Van Noort, J.M.1    Van Der Drift, A.C.2
  • 3
    • 0028572551 scopus 로고
    • Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class II MHC invariant chain
    • Mizuochi T, Yee ST, Kasai M et al. Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class II MHC invariant chain. Immunol Lett 1994;43:189-193.
    • (1994) Immunol Lett , vol.43 , pp. 189-193
    • Mizuochi, T.1    Yee, S.T.2    Kasai, M.3
  • 4
    • 0029083689 scopus 로고
    • Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells
    • Saftig P, Hetman M, Schmahl W et al. Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells. EMBO J 1995;14:3599-3608.
    • (1995) EMBO J , vol.14 , pp. 3599-3608
    • Saftig, P.1    Hetman, M.2    Schmahl, W.3
  • 5
    • 0028998783 scopus 로고
    • Proteolysis of glucagon within hepatic endosomes by membrane-associated cathepsins B and D
    • Authier F, Mort JS, Bell AW et al. Proteolysis of glucagon within hepatic endosomes by membrane-associated cathepsins B and D. J Biol Chem 1995;270:15798-15807.
    • (1995) J Biol Chem , vol.270 , pp. 15798-15807
    • Authier, F.1    Mort, J.S.2    Bell, A.W.3
  • 6
    • 0026629172 scopus 로고
    • Purification and characterization of a cathepsin D protease from bovine chromaffin granules
    • Krieger TJ, Hook VYH. Purification and characterization of a cathepsin D protease from bovine chromaffin granules. Biochemistry 1992;31:4223-4231.
    • (1992) Biochemistry , vol.31 , pp. 4223-4231
    • Krieger, T.J.1    Hook, V.Y.H.2
  • 7
    • 0024382416 scopus 로고
    • Cleavage of parathyroid hormone in macrophage endosomes illustrates a novel pathway for intracellular processing of proteins
    • Diment S, Martin KJ, Stahl PD. Cleavage of parathyroid hormone in macrophage endosomes illustrates a novel pathway for intracellular processing of proteins. J Biol Chem 1989;264:13403-13406.
    • (1989) J Biol Chem , vol.264 , pp. 13403-13406
    • Diment, S.1    Martin, K.J.2    Stahl, P.D.3
  • 8
    • 0028947294 scopus 로고
    • Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: Evidence for early upregulation of the endosomal-lysosomal system
    • Cataldo AM, Barnett JL, Berman SA et al. Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early upregulation of the endosomal-lysosomal system. Neuron 1995;14:671-680.
    • (1995) Neuron , vol.14 , pp. 671-680
    • Cataldo, A.M.1    Barnett, J.L.2    Berman, S.A.3
  • 9
    • 0029101381 scopus 로고
    • Comparative analysis of cathepsin L, cathepsin D and collagenase messenger RNA expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis by in situ hybridization
    • Keyszer GM, Heer AH, Kriegsmann J et al. Comparative analysis of cathepsin L, cathepsin D and collagenase messenger RNA expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis by in situ hybridization. Arthritis Rheum 1995;38:976-984.
    • (1995) Arthritis Rheum , vol.38 , pp. 976-984
    • Keyszer, G.M.1    Heer, A.H.2    Kriegsmann, J.3
  • 10
    • 0023633923 scopus 로고
    • Estrogen-induced lysosomal proteases secreted by breast cancer cells. A role in carcinogenesis?
    • Rochefort H, Capony F, Garcia M et al. Estrogen-induced lysosomal proteases secreted by breast cancer cells. A role in carcinogenesis? J Cell Biochem 1987;35:17-29.
    • (1987) J Cell Biochem , vol.35 , pp. 17-29
    • Rochefort, H.1    Capony, F.2    Garcia, M.3
  • 11
    • 0025864675 scopus 로고
    • Molecular organization of the human cathepsin D gene
    • Redecker B, Heckendorf B, Grosch HW et al. Molecular organization of the human cathepsin D gene. DNA and Cell Biol 1991;10:423-431.
    • (1991) DNA and Cell Biol , vol.10 , pp. 423-431
    • Redecker, B.1    Heckendorf, B.2    Grosch, H.W.3
  • 12
    • 0023840142 scopus 로고
    • Cloning and sequencing of the 52K cathepsin D cDNA of MCF7 breast cancer cells and mapping on chromosome 11
    • Augereau P, Garcia M, Mattei MG et al. Cloning and sequencing of the 52K cathepsin D cDNA of MCF7 breast cancer cells and mapping on chromosome 11. Mol Endocrinol 1988;2:186-192.
    • (1988) Mol Endocrinol , vol.2 , pp. 186-192
    • Augereau, P.1    Garcia, M.2    Mattei, M.G.3
  • 13
    • 0025290527 scopus 로고
    • The structure and function of the aspartic proteinases
    • Davies DR. The structure and function of the aspartic proteinases. Ann Rev Biophys Chem 1990;19:189-215.
    • (1990) Ann Rev Biophys Chem , vol.19 , pp. 189-215
    • Davies, D.R.1
  • 14
    • 0022555844 scopus 로고
    • Lysosomal enzymes and their receptors
    • Von Figura K, Hasilik A. Lysosomal enzymes and their receptors. Ann Rev Biochem 1986;55:167-193.
    • (1986) Ann Rev Biochem , vol.55 , pp. 167-193
    • Von Figura, K.1    Hasilik, A.2
  • 15
    • 0026637316 scopus 로고
    • Structure and function of the mannose-6-phosphate/insulin like growth factor II receptors
    • Kornfeld S. Structure and function of the mannose-6-phosphate/insulin like growth factor II receptors. Ann Rev Biochem 1992;61:307-330.
    • (1992) Ann Rev Biochem , vol.61 , pp. 307-330
    • Kornfeld, S.1
  • 16
    • 0027932822 scopus 로고
    • Differential sorting of lysosomal enzymes in mannose-6-phosphate receptor-deficient fibroblasts
    • Ludwig T, Munier-Lehmann H, Bauer U et al. Differential sorting of lysosomal enzymes in mannose-6-phosphate receptor-deficient fibroblasts. EMBO J 1994;13:3430-3437.
    • (1994) EMBO J , vol.13 , pp. 3430-3437
    • Ludwig, T.1    Munier-Lehmann, H.2    Bauer, U.3
  • 17
    • 0024321224 scopus 로고
    • Increased secretion, altered processing, and glycosylation of pro-cathepsin D in human mammary cancer cells
    • Capony F, Rougeot C, Montcourrier P et al. Increased secretion, altered processing, and glycosylation of pro-cathepsin D in human mammary cancer cells. Cancer Res 1989;49:3904-3909.
    • (1989) Cancer Res , vol.49 , pp. 3904-3909
    • Capony, F.1    Rougeot, C.2    Montcourrier, P.3
  • 18
    • 0024805872 scopus 로고
    • Overexpression and hormonal regulation of procathepsin D in mammary and endometrial cancer
    • Rochefort H, Cavaillès V, Augereau P et al. Overexpression and hormonal regulation of procathepsin D in mammary and endometrial cancer. J Steroid Biochem 1989;34:177-182.
    • (1989) J Steroid Biochem , vol.34 , pp. 177-182
    • Rochefort, H.1    Cavaillès, V.2    Augereau, P.3
  • 19
    • 0024602483 scopus 로고
    • Regulation of cathepsin D and pS2 gene expression by growth factors in MCF7 human breast cancer cells
    • Cavaillès V, Garcia M, Rochefort H. Regulation of cathepsin D and pS2 gene expression by growth factors in MCF7 human breast cancer cells. Mol Endocrinol 1989;3:552-558.
    • (1989) Mol Endocrinol , vol.3 , pp. 552-558
    • Cavaillès, V.1    Garcia, M.2    Rochefort, H.3
  • 20
    • 0028068374 scopus 로고
    • Cathepsin D immunostaining in paraffin-embedded breast cancer cells and macrophages. Correlation with cytosolic assay
    • Roger P, Montcourrier P, Maudelonde T et al. Cathepsin D immunostaining in paraffin-embedded breast cancer cells and macrophages. Correlation with cytosolic assay. Human Path 1994;25:863-871.
    • (1994) Human Path , vol.25 , pp. 863-871
    • Roger, P.1    Montcourrier, P.2    Maudelonde, T.3
  • 21
    • 0029940081 scopus 로고    scopus 로고
    • Cellular localisation by in situ hybridization of cathepsin D, stromelysin 3 and urokinase plasminogen activator RNAs in breast cancer
    • Escot C, Zhao Y, Puech C et al. Cellular localisation by in situ hybridization of cathepsin D, stromelysin 3 and urokinase plasminogen activator RNAs in breast cancer. Br Cancer Res Treat 1996;38:217-226.
    • (1996) Br Cancer Res Treat , vol.38 , pp. 217-226
    • Escot, C.1    Zhao, Y.2    Puech, C.3
  • 22
    • 0027475947 scopus 로고
    • Cathepsin D gene is controlled by a mixed promoter and estrogens stimulate only TATA dependent transcription in breast cancer cells
    • Cavaillès V, Augereau P, Rochefort H. Cathepsin D gene is controlled by a mixed promoter and estrogens stimulate only TATA dependent transcription in breast cancer cells. Proc Natl Acad Sci USA 1993;90:203-207.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 203-207
    • Cavaillès, V.1    Augereau, P.2    Rochefort, H.3
  • 23
    • 0028292442 scopus 로고
    • Characterization of the proximal estrogen responsive element of human cathepsin D gene
    • Augereau P, Mirallès F, Cavaillès V et al. Characterization of the proximal estrogen responsive element of human cathepsin D gene. Mol Endocrinol 1994;8:693-703.
    • (1994) Mol Endocrinol , vol.8 , pp. 693-703
    • Augereau, P.1    Mirallès, F.2    Cavaillès, V.3
  • 24
    • 0023769895 scopus 로고
    • Breast cancer-associated pS2 protein: Synthesis and secretion by normal mucosa
    • Rio MC, Bellocq JP, Daniel JY et al. Breast cancer-associated pS2 protein: synthesis and secretion by normal mucosa. Science 1988;241:705-708.
    • (1988) Science , vol.241 , pp. 705-708
    • Rio, M.C.1    Bellocq, J.P.2    Daniel, J.Y.3
  • 25
    • 10544244241 scopus 로고
    • Estrogen control of progesterone receptor in human breast cancer
    • Horwitz KB, McGuire WL. Estrogen control of progesterone receptor in human breast cancer. J Biol Chem 1978;248:6351-6353.
    • (1978) J Biol Chem , vol.248 , pp. 6351-6353
    • Horwitz, K.B.1    McGuire, W.L.2
  • 26
    • 0028875555 scopus 로고
    • Hormone-dependent regulation of BRCA1 in human breast cancer cells
    • Gudas J, Nguyen HLT, Cowan KH. Hormone-dependent regulation of BRCA1 in human breast cancer cells. Cancer Res 1995;55:4561-4565.
    • (1995) Cancer Res , vol.55 , pp. 4561-4565
    • Gudas, J.1    Nguyen, H.L.T.2    Cowan, K.H.3
  • 27
    • 0011288815 scopus 로고
    • Cloning and sequence analysis of cDNA for human cathepsin D
    • Faust PL, Kornfeld S, Chirgwin JM. Cloning and sequence analysis of cDNA for human cathepsin D. Proc Natl Acad Sci USA 1985;82:4910-4914.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 4910-4914
    • Faust, P.L.1    Kornfeld, S.2    Chirgwin, J.M.3
  • 28
    • 0028335582 scopus 로고
    • Missense polymorphism (C/T224) in the human cathepsin D pro-fragment determined by polymerase chain reaction-single strand conformational polymorphism analysis and possible consequences in cancer cells
    • Touitou I, Capony F, Brouillet JP et al. Missense polymorphism (C/T224) in the human cathepsin D pro-fragment determined by polymerase chain reaction-single strand conformational polymorphism analysis and possible consequences in cancer cells. Eur J Cancer 1994;30:390-394.
    • (1994) Eur J Cancer , vol.30 , pp. 390-394
    • Touitou, I.1    Capony, F.2    Brouillet, J.P.3
  • 29
    • 0023294066 scopus 로고
    • Phosphorylation, glycosylation and proteolytic activity of the 52K estrogen-induced protein secreted by MCF7 cells
    • Capony F, Morisset M, Barrett AJ et al. Phosphorylation, glycosylation and proteolytic activity of the 52K estrogen-induced protein secreted by MCF7 cells. J Cell Biol 1987;104:253-262.
    • (1987) J Cell Biol , vol.104 , pp. 253-262
    • Capony, F.1    Morisset, M.2    Barrett, A.J.3
  • 30
    • 0024312845 scopus 로고
    • Biosynthesis of lysosomal endopeptidases
    • Erickson AH. Biosynthesis of lysosomal endopeptidases. J Cell Biochem 1989;40:31-41.
    • (1989) J Cell Biochem , vol.40 , pp. 31-41
    • Erickson, A.H.1
  • 31
    • 0023784140 scopus 로고
    • r 52.000 cathepsin D secreted by breast cancer cells
    • r 52.000 cathepsin D secreted by breast cancer cells. Cancer Res 1988;48:3688-3692.
    • (1988) Cancer Res , vol.48 , pp. 3688-3692
    • Briozzo, P.1    Morisset, M.2    Capony, F.3
  • 32
    • 0021133540 scopus 로고
    • Effects of antiestrogens on the estrogen-regulated pS2 RNA, and the 52-k and 160-kilodalton proteins in MCF7 cells and two tamoxifen resistant sublines
    • Westley B, May FEB, Brown AMC et al. Effects of antiestrogens on the estrogen-regulated pS2 RNA, and the 52-k and 160-kilodalton proteins in MCF7 cells and two tamoxifen resistant sublines. J Biol Chem 1984; 259:10030-10035.
    • (1984) J Biol Chem , vol.259 , pp. 10030-10035
    • Westley, B.1    May, F.E.B.2    Brown, A.M.C.3
  • 33
    • 0028267222 scopus 로고
    • Anti-proliferative and anti-estrogenic effects of ICI 164,384 and ICI 182,780 in 4-OH-tamoxifen-resistant human breast cancer cells
    • Coopman P, Garcia M, Brunner N et al. Anti-proliferative and anti-estrogenic effects of ICI 164,384 and ICI 182,780 in 4-OH-tamoxifen-resistant human breast cancer cells. Int J Cancer 1994;56:295-300.
    • (1994) Int J Cancer , vol.56 , pp. 295-300
    • Coopman, P.1    Garcia, M.2    Brunner, N.3
  • 34
    • 0026001074 scopus 로고
    • Estradiol down regulates the mannose-6-phosphate/IGFII receptor gene and induces cathepsin D in breast cancer cells: A receptor saturation mechanism to increase the secretion of lysosomal proenzymes
    • Mathieu M, Vignon F, Capony F et al. Estradiol down regulates the mannose-6-phosphate/IGFII receptor gene and induces cathepsin D in breast cancer cells: a receptor saturation mechanism to increase the secretion of lysosomal proenzymes. Mol Endocrinol 1991;5:815-822.
    • (1991) Mol Endocrinol , vol.5 , pp. 815-822
    • Mathieu, M.1    Vignon, F.2    Capony, F.3
  • 35
    • 0023943263 scopus 로고
    • Cathepsin D is membrane-associated in macrophage endosomes
    • Diment S, Leech MS, Stahl PD. Cathepsin D is membrane-associated in macrophage endosomes. J Biol Chem 1988;263:6901-6907.
    • (1988) J Biol Chem , vol.263 , pp. 6901-6907
    • Diment, S.1    Leech, M.S.2    Stahl, P.D.3
  • 36
    • 0026424625 scopus 로고
    • Identification of subcellular compartments involved in biosynthetic processing of cathepsin D
    • Rijnboutt S, Aerts HMFG, Geuze HJ et al. Identification of subcellular compartments involved in biosynthetic processing of cathepsin D. J Biol Chem 1991;266:4862-4868.
    • (1991) J Biol Chem , vol.266 , pp. 4862-4868
    • Rijnboutt, S.1    Aerts, H.M.F.G.2    Geuze, H.J.3
  • 37
    • 0028130332 scopus 로고
    • Specific mannose-6-phosphate receptor-independent sorting of pro-cathepsin D in breast cancer cells
    • Capony F, Braulke T, Rougeot C et al. Specific mannose-6-phosphate receptor-independent sorting of pro-cathepsin D in breast cancer cells. Exp Cell Res 1994;215:154-163.
    • (1994) Exp Cell Res , vol.215 , pp. 154-163
    • Capony, F.1    Braulke, T.2    Rougeot, C.3
  • 38
    • 0026779307 scopus 로고
    • Cathepsin D in breast cancer: A tissue marker associated with metastasis
    • Rochefort H. Cathepsin D in breast cancer: a tissue marker associated with metastasis. Eur J Cancer 1992;28A:1780-1783.
    • (1992) Eur J Cancer , vol.28 A , pp. 1780-1783
    • Rochefort, H.1
  • 39
    • 0026726643 scopus 로고
    • Cathepsin D as a prognostic indicator for node-negative breast cancer patients using both immunoassays and enzymatic assays
    • Kute TE, Shao ZM, Sugg NK et al. Cathepsin D as a prognostic indicator for node-negative breast cancer patients using both immunoassays and enzymatic assays. Cancer Res 1992;52:5198-5203.
    • (1992) Cancer Res , vol.52 , pp. 5198-5203
    • Kute, T.E.1    Shao, Z.M.2    Sugg, N.K.3
  • 40
    • 0028037891 scopus 로고
    • Cathepsin D and breast cancer: Useful?
    • Cardiff RD. Cathepsin D and breast cancer: useful? Hum Pathol 1994;25:847-848.
    • (1994) Hum Pathol , vol.25 , pp. 847-848
    • Cardiff, R.D.1
  • 41
    • 0029966513 scopus 로고    scopus 로고
    • Cathepsin D and breast cancer
    • Westley BR, May FEB. Cathepsin D and breast cancer. Eur J Cancer 1996;32A:15-24.
    • (1996) Eur J Cancer , vol.32 A , pp. 15-24
    • Westley, B.R.1    May, F.E.B.2
  • 42
    • 85035187894 scopus 로고    scopus 로고
    • The prognostic value of the urokinase system (uPA/uPAR/PAI-1/PAI-2) and cathepsin D in primary and recurrent breast cancer
    • Panama City Beach, Florida, USA, March 1-5
    • Foekens JA, Peters HA, Look MP et al. The prognostic value of the urokinase system (uPA/uPAR/PAI-1/PAI-2) and cathepsin D in primary and recurrent breast cancer. AACR Special Conference on "Proteases and Protease Inhibitors", Panama City Beach, Florida, USA, March 1-5, 1996.
    • (1996) AACR Special Conference on "Proteases and Protease Inhibitors"
    • Foekens, J.A.1    Peters, H.A.2    Look, M.P.3
  • 43
    • 0028967470 scopus 로고
    • Expression of cathepsin D in primary and metastatic human melanoma and dysplastic nevi
    • Podhajcer OL, Bover L, Bravo AI et al. Expression of cathepsin D in primary and metastatic human melanoma and dysplastic nevi. J Invest Dermatol 1995;104:340-344.
    • (1995) J Invest Dermatol , vol.104 , pp. 340-344
    • Podhajcer, O.L.1    Bover, L.2    Bravo, A.I.3
  • 44
    • 0026340686 scopus 로고
    • Increased plasma cathepsin D concentration in hepatic carcinoma and cirrhosis but not in breast cancer
    • Brouillet JP, Hanslick B, Maudelonde T et al. Increased plasma cathepsin D concentration in hepatic carcinoma and cirrhosis but not in breast cancer. Clin Biochem 1991;24:491-496.
    • (1991) Clin Biochem , vol.24 , pp. 491-496
    • Brouillet, J.P.1    Hanslick, B.2    Maudelonde, T.3
  • 45
    • 0028936797 scopus 로고
    • Cathepsin D content in colorectal cancer. Correlation with cathepsin D activity and other biological parameters: A preliminary report
    • Tumminello FM, Gebbia N, Pizzolanti G et al. Cathepsin D content in colorectal cancer. Correlation with cathepsin D activity and other biological parameters: a preliminary report. Oncology 1995;52:237-242.
    • (1995) Oncology , vol.52 , pp. 237-242
    • Tumminello, F.M.1    Gebbia, N.2    Pizzolanti, G.3
  • 46
    • 0029041018 scopus 로고
    • Quantitative immunohistochemical determination of cathepsin D levels in prostatic carcinoma biopsies. Correlation with tumor grade, stage, PSA level, and DNA ploidy status
    • Ross JS, Nazeer T, Figge HL et al. Quantitative immunohistochemical determination of cathepsin D levels in prostatic carcinoma biopsies. Correlation with tumor grade, stage, PSA level, and DNA ploidy status. Am J Clin Path 1995;104:36-41.
    • (1995) Am J Clin Path , vol.104 , pp. 36-41
    • Ross, J.S.1    Nazeer, T.2    Figge, H.L.3
  • 47
    • 0024439007 scopus 로고
    • r 52,000 cathepsin-D and poor prognosis in primary human breast cancer
    • r 52,000 cathepsin-D and poor prognosis in primary human breast cancer. Cancer Res 1989;49:6008-6014.
    • (1989) Cancer Res , vol.49 , pp. 6008-6014
    • Thorpe, S.M.1    Rochefort, H.2    Garcia, M.3
  • 48
    • 0025596963 scopus 로고
    • Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency
    • Garcia D, Derocq D, Pujol Pet al. Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency. Oncogene 1990;5:1809-1814.
    • (1990) Oncogene , vol.5 , pp. 1809-1814
    • Garcia, D.1    Derocq, D.2    Pujol, P.3
  • 49
    • 0028281477 scopus 로고
    • Cathepsin D maturation and its stimulatory effect on metastasis are prevented by addition of KDEL retention signal
    • Liaudet E, Garcia M, Rochefort H. Cathepsin D maturation and its stimulatory effect on metastasis are prevented by addition of KDEL retention signal. Oncogene 1994;9:1145-1154.
    • (1994) Oncogene , vol.9 , pp. 1145-1154
    • Liaudet, E.1    Garcia, M.2    Rochefort, H.3
  • 50
    • 0027287596 scopus 로고
    • Immunoradiometric assay of pro-cathepsin D in breast cancer cytosol: Relative prognostic value versus total cathepsin D
    • Brouillet JP, Spyratos F, Hacene K et al. Immunoradiometric assay of pro-cathepsin D in breast cancer cytosol: relative prognostic value versus total cathepsin D. Eur J Cancer 1993;29A:1248-1251.
    • (1993) Eur J Cancer , vol.29 A , pp. 1248-1251
    • Brouillet, J.P.1    Spyratos, F.2    Hacene, K.3
  • 51
    • 0028791436 scopus 로고
    • Compartmentalized signal transduction by receptor tyrosine kinases
    • Baass PC, Di Guglielmo M, Authier F et al. Compartmentalized signal transduction by receptor tyrosine kinases. Trends Cell Biol 1995;5:465-470.
    • (1995) Trends Cell Biol , vol.5 , pp. 465-470
    • Baass, P.C.1    Di Guglielmo, M.2    Authier, F.3
  • 52
    • 0025147271 scopus 로고
    • Cathepsin D in breast cancer cells can digest extracellular matrix in large acidic vesicles
    • Montcourrier P, Mangeat P, Salazar G et al. Cathepsin D in breast cancer cells can digest extracellular matrix in large acidic vesicles. Cancer Res 1990;50:6045-6054.
    • (1990) Cancer Res , vol.50 , pp. 6045-6054
    • Montcourrier, P.1    Mangeat, P.2    Salazar, G.3
  • 53
    • 0027930711 scopus 로고
    • Characterization of very acidic phagosomes in breast cancer cells and their association with invasion
    • Montcourrier P, Mangeat P, Valembois C et al. Characterization of very acidic phagosomes in breast cancer cells and their association with invasion. J Cell Science 1994;107:2381-2391.
    • (1994) J Cell Science , vol.107 , pp. 2381-2391
    • Montcourrier, P.1    Mangeat, P.2    Valembois, C.3
  • 54
    • 0015899482 scopus 로고
    • Phagocytic tumour cells
    • Spivak JL. Phagocytic tumour cells. Scand J Hematol 1973;11:253-256.
    • (1973) Scand J Hematol , vol.11 , pp. 253-256
    • Spivak, J.L.1
  • 55
    • 0018820404 scopus 로고
    • Phagocytic capacity of invasive malignant cells in the three-dimensional culture
    • Van Peteghem MC, Mareel MM, De Bruyne GK. Phagocytic capacity of invasive malignant cells in the three-dimensional culture. Virchows Arch B Cell Path 1980;55:167-193.
    • (1980) Virchows Arch B Cell Path , vol.55 , pp. 167-193
    • Van Peteghem, M.C.1    Mareel, M.M.2    De Bruyne, G.K.3
  • 56
    • 0026027556 scopus 로고
    • Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
    • Liotta LA, Steeg PS, Stetler-Stevenson WG. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 1991;64:327-336.
    • (1991) Cell , vol.64 , pp. 327-336
    • Liotta, L.A.1    Steeg, P.S.2    Stetler-Stevenson, W.G.3
  • 57
    • 0023774523 scopus 로고
    • Cathepsin D inactivates cysteine proteinase inhibitors cystatins
    • Lenarcic B, Kos J, Dolens I. Cathepsin D inactivates cysteine proteinase inhibitors cystatins. Biochem Biophys Res Commun 1988;154:765-772.
    • (1988) Biochem Biophys Res Commun , vol.154 , pp. 765-772
    • Lenarcic, B.1    Kos, J.2    Dolens, I.3
  • 58
    • 0022506920 scopus 로고
    • Autocrine growth stimulation of the MCF7 breast cancer cells by the estrogen-regulated 52k protein
    • Vignon F, Capony F, Chambon M et al. Autocrine growth stimulation of the MCF7 breast cancer cells by the estrogen-regulated 52k protein. Endocrinology 1986;118:1537-1545.
    • (1986) Endocrinology , vol.118 , pp. 1537-1545
    • Vignon, F.1    Capony, F.2    Chambon, M.3
  • 59
    • 0028352140 scopus 로고
    • Mitogenic activity of procathepsin D purified for conditioned medium of breast cancer cells by affinity chromatography on pepstatinyl agarose
    • Stewart AJ, Piggott NH, May FEB et al. Mitogenic activity of procathepsin D purified for conditioned medium of breast cancer cells by affinity chromatography on pepstatinyl agarose. Int J Cancer 1994;57:715-718.
    • (1994) Int J Cancer , vol.57 , pp. 715-718
    • Stewart, A.J.1    Piggott, N.H.2    May, F.E.B.3
  • 60
    • 0029099015 scopus 로고
    • Transfected cathepsin D stimulates high density cancer cell growth by inactivating secreted growth inhibitors
    • Liaudet E, Derocq D, Rochefort H et al. Transfected cathepsin D stimulates high density cancer cell growth by inactivating secreted growth inhibitors. Cell Growth Diff 1995;6:1045-1052.
    • (1995) Cell Growth Diff , vol.6 , pp. 1045-1052
    • Liaudet, E.1    Derocq, D.2    Rochefort, H.3
  • 61
    • 0029562902 scopus 로고
    • Steps in tumor metastasis: New concepts from intravital videomicroscopy
    • Chambers AF, MacDonald IC, Schmidt EE et al. Steps in tumor metastasis: new concepts from intravital videomicroscopy. Cancer Met Review 1995;14:279-301.
    • (1995) Cancer Met Review , vol.14 , pp. 279-301
    • Chambers, A.F.1    MacDonald, I.C.2    Schmidt, E.E.3
  • 62
    • 0028920370 scopus 로고
    • Endogenous cathepsin D-mediated hydrolysis of insulin-like growth factor-binding proteins in cultured human prostatic carcinoma cells
    • Conover CA, Perry JE, Tindall DJ. Endogenous cathepsin D-mediated hydrolysis of insulin-like growth factor-binding proteins in cultured human prostatic carcinoma cells. J Clin Endocrinol Metab 1995;80:987-992.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 987-992
    • Conover, C.A.1    Perry, J.E.2    Tindall, D.J.3
  • 63
    • 0025753774 scopus 로고
    • MCF7 mammary cancer cells respond to bFGF and internalize it following its release from extracellular matrix: A permissive role of cathepsin D
    • Briozzo P, Badet J, Capony F et al. MCF7 mammary cancer cells respond to bFGF and internalize it following its release from extracellular matrix: a permissive role of cathepsin D. Exp Cell Res 1991;194:252-259.
    • (1991) Exp Cell Res , vol.194 , pp. 252-259
    • Briozzo, P.1    Badet, J.2    Capony, F.3


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