Serine protease inhibitors suppress cytochrome c-mediated caspase-9 activation and apoptosis during hypoxia-reoxygenation

Biochemical Journal

Volumn 347, Issue 3, 2000, Pages 669-677

  Dong, Zheng ^a   Saikumar, Pothana ^a   Patel, Yogendra ^a   Weinberg, Joel M ^b   Venkatachalam, Manjeri A ^a  

^a Univ of Texas Hlth Science Center ^*  (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Apoptosome; ATP depletion; Reoxygenation; TPCK

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CHYMOTRYPSIN INHIBITOR; COUMARIN DERIVATIVE; CYTOCHROME C; DEOXYADENOSINE TRIPHOSPHATE; ENZYME PRECURSOR; KETONE DERIVATIVE; PROTEIN BCL 2; SERINE PROTEINASE INHIBITOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; HYPOXIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; RAT; REOXYGENATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; BIOLOGICAL TRANSPORT; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL HYPOXIA; CELL LINE; CELL SIZE; CYTOCHROME C GROUP; CYTOSOL; DEOXYADENINE NUCLEOTIDES; ENZYME ACTIVATION; ENZYME PRECURSORS; KIDNEY TUBULES, PROXIMAL; MITOCHONDRIA; OXYGEN; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SERINE PROTEINASE INHIBITORS;

EID: 0034194258     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3470669     Document Type: Article

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