Serine protease inhibitors suppress cytochrome c-mediated caspase-9 activation and apoptosis during hypoxia-reoxygenation

Biochemical Journal

Volumn 347, Issue 3, 2000, Pages 669-677

  Dong, Zheng ^a   Saikumar, Pothana ^a   Patel, Yogendra ^a   Weinberg, Joel M ^b   Venkatachalam, Manjeri A ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Apoptosome; ATP depletion; Reoxygenation; TPCK

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CHYMOTRYPSIN INHIBITOR; COUMARIN DERIVATIVE; CYTOCHROME C; DEOXYADENOSINE TRIPHOSPHATE; ENZYME PRECURSOR; KETONE DERIVATIVE; PROTEIN BCL 2; SERINE PROTEINASE INHIBITOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; HYPOXIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; RAT; REOXYGENATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; BIOLOGICAL TRANSPORT; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL HYPOXIA; CELL LINE; CELL SIZE; CYTOCHROME C GROUP; CYTOSOL; DEOXYADENINE NUCLEOTIDES; ENZYME ACTIVATION; ENZYME PRECURSORS; KIDNEY TUBULES, PROXIMAL; MITOCHONDRIA; OXYGEN; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SERINE PROTEINASE INHIBITORS;

EID: 0034194258     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3470669     Document Type: Article

References (33)

1. 1 Cohen, G. M. (1997) Biochem. J. 326, 1-16
2. 2 Salvesen, G. S. and Dixit, V. M. (1997) Cell 91, 443-446
3. 3 Cryns, V. and Yuan, J. (1998) Genes Dev. 12, 1551-1570
4. 4 Thornberry, N. A. and Lazebnik, Y. (1998) Science 281, 1312-1316
5. 5 Kumar, S. and Harvey, N. L. (1995) FEBS Lett. 375, 169-173
6. 6 Martin, S. J. and Green, D. R. (1995) Cell 82, 349-352
7. 7 Weaver, V. M , Lach, B., Walker, P. R. and Sikorska, M. (1993) Biochem. Cell Biol. 71, 488-500
8. 8 Fearnhead, H. O., Rivett, A. J., Dinsdale, D. and Cohen, G. M. (1995) FEBS Lett. 357, 242-246
9. 9 Weis, M., Schlegel, J., Kass, G. E., Holmstrom, T. H., Peters, I., Eriksson, J., Orrenius, S. and Chow, S. C. (1995) Exp. Cell Res. 219, 699-708
10. 10 Chow, S. C., Weis, M., Kass, G. E., Holmstrom, T. H., Eriksson, J. E. and Orrenius, S. (1995) FEBS Lett. 364, 134-138
11. 11 Shimizu, T. and Pommier, Y. (1997) Leukemia 11, 1238-1244
12. 12 Jones, R. A., Johnson, V. L., Buck, N. R., Dobrota, M., Hinton, R. H., Chow, S. C. and Kass, G. E. (1998) Hepatology 27, 1632-1642
13. 13 Saikumar, P., Dang, Z., Patel, Y., Hopfer, U., Weinberg, J. M. and Venkatachalam, M. A. (1998) Oncogene 17, 3401-3415
14. 14 Saikumar, P., Dong, Z., Weinberg, J. M. and Venkatachalam, M. A. (1998) Oncogene 17, 3341-3349
15. 15 Dong, Z., Patel, Y., Saikumar, P., Weinberg, J. M. and Venkatachalam, M. A. (1998) Lab. Invest. 78, 657-668
16. 16 Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P. et al. (1997) J. Biol. Chem. 272, 17907-17911
17. 17 Stennicke, H. R. and Salvesen, G. S. (1997) J. Biol. Chem. 272, 25719-25723
18. 18 Talanian, R. V., Quinlan, C., Trautz, S., Hackett, M. C., Mankovich, J. A., Banach, D., Ghayur, T., Brady, K. D. and Wong, W. W. (1997) J. Biol. Chem. 272, 9677-9682
19. 19 Slee, E. A., Zhu, H., Chow, S. C., MacFarlane, M., Nicholson, D. W. and Cohen, G. M. (1996) Biochem, J. 315, 21-24
20. 20 Cotran, T. S., Kumar, V. and Collins, T. (1998) in Robbins Pathologic Basis of Disease (6th edition), pp. 1-29, WB Saunders Company, Philadelphia
21. 21 Zhou, Q. and Salvesen, G. S. (1997) Biochem. J. 324, 361-364
22. 22 Beynon, R. J. and Salvesen, G. (1996) in Proteolytic Enzymes: a Practical Approach (Beynon, R. J. and Bond, J. S., eds.), pp. 241-249, Oxford University Press Inc., New York
23. 23 Sadoul, R., Fernandez, P. A., Quiquerez, A. L., Martinou, I., Maki, M., Schroter, M., Becherer, J. D., Irmler, M., Tschopp, J. and Martinou, J. C. (1996) EMBO J. 15, 3845-3852
24. 24 Ashkenazi, A. and Dixit, V. M. (1998) Science 281, 1305-1308
25. 25 Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S. and Wang, X. (1998) Cell 91, 479-489
26. 26 Zou, H., Li, Y., Liu, X. and Wang, X. (1999) J. Biol. Chem. 274, 11549-11556
27. 27 Cain, K., Brown, D. G., Langlais, C. and Cohen, G. M. (1999) J. Biol. Chem. 274, 22686-22692
28. 28 Shimizu, S., Eguchi, Y., Kamiike, W., Akao, Y., Kosaka, H., Hasegawa, J , Matsuda, H. and Tsujimoto, Y. (1996) Am. J. Physiol. 271, G949-G958
29. 29 Harrison-Shostak, D. C., Lemasters, J. J., Edgell, C. J. and Herman, B. (1997) Biochem. Biophys. Res. Commun. 231, 844-847
30. 30 Hara, H., Friedlander, R. M., Gagliardini, V., Ayata, C., Fink, K., Huang, Z., Shimizu-Sasamata, M., Yuan, J. and Moskowitz, M. A. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 2007-2012
31. 31 Yaoita, H., Ogawa, K., Maehara, K. and Maruyama, Y. (1997) Circulation 97, 276-281
32. 32 Zhu, H., Dinsdale, D., Alnemri, E. S. and Cohen, G. M. (1997) Cell Death Differ. 4, 590-599
33. 33 Zhuang, J. and Cohen, G. M. (1998) Toxicol. Lett. 102/103, 121-129