Grazing increases the unsaturated fatty acid concentration of milk from grass-fed cows: A review of the contributing factors, challenges and future perspectives

European Journal of Lipid Science and Technology

Volumn 117, Issue 9, 2015, Pages 1345-1369

  Elgersma, Anjo ^a  

^a NONE   (Netherlands)

Author keywords

Biohydrogenation; CLA; FA distribution; FA nomenclature; Lipid analysis; N 3 PUFA; Profile; Trans fatty acids; Transfer

Indexed keywords

EID: 84939549445     PISSN: 14387697     EISSN: 14389312     Source Type: Journal    
DOI: 10.1002/ejlt.201400469     Document Type: Review

References (152)

1. Lavillonnière, F., Martin, J. C., Bougnoux, P., Sébédio, J.-L., Analysis of conjugated linoleic acid isomers and content in French cheeses. J. Am. Oil Chem. Soc. 1998, 75, 343-352.
2. Dhiman, T. R., Anand, G. R., Satter, L. D., Pariza, M. W., Conjugated linoleic acid content of milk from cows fed different diets. J. Dairy Sci. 1999, 82, 2146-2156.
3. Kalač, P., Samkova, E., The effects of feeding various forages on fatty acid composition of bovine milk: A review. Czech J. Animal Sci. 2010, 55, 521-537.
4. Vuuren, A. M. van, Digestion and nitrogen metabolism of grass fed dairy cows. PhD Dissertation, Wageningen Agricultural University, Wageningen, The Netherlands 1993.
5. Kolver, E. S., Muller, L. D., Performance and nutrient intake of high producing Holstein cows consuming pasture or a total mixed ration. J. Dairy Sci. 1998, 81, 1403-1411.
6. Gibb, M. J., Huckle, C. A., Nuthall, R., Rook, A. J., The effect of physiological state (lactating or dry) and sward surface height on grazing behaviour and intake by dairy cows. Appl. Animal Behav. Sci. 1999, 63, 269-287.
7. Krause, K. M., Oetzel, G. R., Inducing subacute ruminal acidosis in lactating dairy cows. J. Dairy Sci. 2005, 88, 3633-3639.
8. Wales, W. J., Doyle, P. T., Effect of grain and straw supplementation on marginal milk production responses and rumen function of cows grazing highly digestible subterranean clover pasture. Aust. J. Exp. Agric. 2003, 43, 467-474.
9. Mould, F. L., Orskov, E. R., Mann, S. O., Associative effects of mixed feeds. I. Effects of type and level of supplementation and the influence of the rumen fluid pH on cellulolysis in vivo and dry matter digestion of various roughages. Anim. Feed Sci. Technol. 1983, 10, 15-30.
10. Leddin, C. M., Stockdale, C. R., Hill, J., Heard, J. W., Doyle, P. T., Increasing amounts of crushed wheat fed with Persian clover herbage reduced ruminal pH and dietary fibre digestibility in lactating dairy cows. Anim. Prod. Sci. 2010, 50, 837-846.
11. Doyle, P. T., Francis, S. A, Stockdale, C. R., Associative effects between feeds when concentrate supplements are fed to grazing dairy cows: A review of likely impacts on metabolisable energy supply. Aust. J. Agric. Res. 2005, 56, 1315-1329.
12. Dixon, R. M., Stockdale, C. R., Associative effects between forages and grains: Consequences for feed utilisation. Aust. J. Agric. Res 1999, 50, 757-774.
13. Elgersma, A., New developments in the Netherlands: Dairies reward grazing because of public perception. Grassl. Sci. Eur. 2012, 17, 420-422.
14. Halfa, A. N., MacAdam, J. W., Soder, K. J., Sustainability of US organic beef and dairy production systems: Soil, plant and cattle interactions. Review. Sustainability 2013, 5, 3009-3034.
15. Schwendel, B. H., Wester, T. J., Morel, P. C. H., Tavendale, M. H., et al., Invited review: Organic and conventionally produced milk-An evaluation of factors influencing milk composition. J. Dairy Sci. 2015, 98, 721-746.
16. Chilliard, Y, Glasser, F., Ferlay, A., Bernard, L., et al., Diet, rumen biohydrogenation and nutritional quality of cow and goat milk fat. Eur. J. Lipid Sci. Tech. 2007, 109, 828-855.
17. Jensen, R. G., The composition of bovine milk lipids: January 1995 to December 2000. J. Dairy Sci. 2002, 85, 295-350.
18. Precht, D., Molkentin, J., Trans fatty acids: Implications for health, analytical methods, incidence in edible fats and intake. Die Nahrung 1995, 39, 343-374.
19. Precht, D., Molkentin, J., Frequency distributions of conjugated linoleic acid and trans fatty acid contents in European bovine milk fats. Michwissenschaft 2000, 55, 687-691.
20. Aldai, N., Renobales de, M., Barron, L. J. R., Kramer, J. K. G., What are the trans fatty acids issues in foods after discontinuation of industrially produced trans fats? Ruminant products, vegetable oils, and synthetic supplements. Eur. J. Lipid Sci. Technol. 2013, 115, 1378-1401.
21. Gibb, M. J., Huckle, C. A., Nuthall, R., Rook, A. J., Effect of sward surface height on intake and grazing behaviour by lactating Holstein Friesian cows. Grass Forage Sci. 1997, 52, 309-321.
22. McGilloway, D. A., Cushnahan, A., Laidlaw, A. S., Maine, C. S., Kilpatrick, D. J., The relationship between level of sward height reduction in a rotationally grazed sward and short-term intake rates of dairy cows. Grass Forage Sci. 1999, 54, 116-126.
23. Rook, A. J, in: Hopkins, A. (Ed.), Grass, Its Production and Utilization, Blackwell Science, Oxford, UK 2000, pp. 229-246.
24. Hodgson, J., The control of herbage intake in the grazing ruminant. Proc. Nutr. Soc. 1985, 44, 339-346.
25. Forbes, T. D. A., Researching the plant-animal interface: The investigation of ingestive behavior in grazing animals. J. Animal Sci. 1988, 66, 2369-2379.
26. Forbes, J. M., in: Fulkerson, W. J., Donaghy, D. J. (Eds.), Voluntary Feed Intake and Diet Selection in Farm Animals, CAB International, Wallingford, UK 1995.
27. Parsons, A. J., Chapman, D. F., in: Hopkins, A. (Ed.), Grass, Its Production and Utilisation, Blackwell Science, Oxford, UK 2000, pp. 31-89.
28. Laca, E. A., Ungar, E. D., Seligman, N., Demment, M. W., Effects of sward height and bulk density on bite dimensions of cattle grazing homogeneous swards. Grass Forage Sci. 1992, 47, 91-102.
29. Laca, E. A., Ungar, E. D., Demment, M. W., Mechanisms of handling time and intake rate of a large mammalian grazer. Appl. Animal Behav. Sci 1994, 39, 3-19.
30. Phillips, C. J. C., Leaver, J. D., Seasonal and diurnal variation in grazing behaviour of dairy cows. In: Grazing. Hurley. 1986, 98-104.
31. Taweel, H. Z., Tas, B., Smit, H. J., Elgersma, A., et al., Grazing behavior, intake, rumen function and milk production of dairy cows offered Lolium perenne containing different levels of water-soluble carbohydrates. Livest. Sci. 2006, 102, 33-41.
32. Orr, R. J., Rutter, S. M., Penning, P. D., Rook, A. J., Matching grass supply to grazing patterns for dairy cows. Grass Forage Sci. 2001, 56, 352-361.
33. Elgersma, A., Tamminga, S., Dijkstra, J., in: Elgersma, A., Dijkstra, J., Tamminga, S. (Eds.), Fresh Herbage for Dairy Cattle, Springer, Wageningen, The Netherlands 2006, pp. 175-194.
34. Bauchart, D., Vérité, R., Rémond, B., Long-chain fatty acid digestion in lactating cows fed fresh grass from spring to autumn. Can. J. An. Sci. 1984, 330-331.
35. Hawke, J. C., in: Butler, G. W., Bailey, R. W. (Eds.), Chemistry and Biochemistry of Herbage, Academic Press, London 1973, pp. 213-263.
36. Iba, L., Acclimative response to temperature stress in higher plants: Approaches of gene engineering for temperature tolerance. Annu. Rev. Plant Biology 2002, 532, 25-245.
37. Routaboul, J., Skidmore, C., Wallis, J. G., Browse, J., Arabidopsis mutants reveal that short- and long-term thermotolerance have different requirements for trienoic fatty acids. J. Exp. Bot. 2012, 63, 1435-1443.
38. Hugly, S., Somerville, C., A role for membrane lipid polyunsaturation in chloroplast biogenesis at low temperature. Plant Physiol. 1992, 99, 197-202.
39. O'Kelly, J. C., Reich, H. P., The fatty acid composition of tropical pastures. J. Agric. Sci. 1976, 86, 427-429.
40. Fernandes, S. A. A., Levantamento exploratório da produção, composição e perfil de ácidos graxos do leite de búfalas em cinco fazendas do estado de São Paulo. PhD Thesis, Universidade de São Paulo, São Paulo 2004.
41. Thomas, H., The role of polyunsaturated fatty acids in senescence. J. Plant Physiol. 1986, 123, 97-105.
42. Dewhurst, R. J., Shingfield, K. J., Lee, M. R. F., Scollan, N. D., Increasing the concentrations of beneficial polyunsaturated fatty acids in milk produced by dairy cows in high-forage systems. Anim. Feed Sci.Techn. 2006, 131, 168-206.
43. Dewhurst, R. J., King, P. J., Effects of extended wilting, shading and chemical additives on the fatty acids in laboratory grass silages. Grass Forage Sci. 1998, 53, 219-224.
44. Doreau, M., Poncet, C., Ruminal biohydrogenation of fatty acids originating from fresh or preserved grass. Repr. Nutr. Dev. 2000, 40, 201.
45. Elgersma, A., Ellen, G., Horst van der, H., Muuse, B. G., et al., Influence of cultivar and cutting date on the fatty acid composition of perennial ryegrass. Grass Forage Sci. 2003, 58, 323-331.
46. Elgersma, A., Søegaard, K., Jensen, S. K., Changes in vitamin and fatty acid contents in grass-red clover herbage after cutting. Grassl. Sci. Eur. 2015, 20, 212-214.
47. Christie, W. W., Lipid Analysis. Isolation, Separation, Identification and Structural Analysis of Lipids, 3rd Edn., The Oily Press, Dundee, UK 2003.
48. Fievez, V., Ensberg, M., Chow, T. T., Demeyer, D., Effects of freezing and drying grass products prior to fatty acid extraction on grass fatty acid and lipid class composition-a technical note. Comm. Appl. Biol. Sci. 2004, 69, 93-102.
49. Elgersma, A., Ellen, G., Horst van der, H., Muuse, B. G., et al., Comparison of the fatty acid composition of fresh and ensiled perennial ryegrass (Lolium perenne L.), affected by cultivar and regrowth interval. Anim. Feed Sci. Technol. 2003, 108, 191-205.
50. Elgersma, A., Maudet, P., Witkowska, I. M., Wever, A. C., Effects of N fertilization and regrowth period on fatty acid concentrations in perennial ryegrass (Lolium perenne L.). Ann. Appl. Biol. 2005, 147, 145-152.
51. Dewhurst, R. J., Scollan, N. D., Youeel, S. J., Tweed, K. S., Humphreys, M. O., Influence of species, cutting date and cutting interval on the fatty acid composition of grasses. Grass Forage Sci. 2001, 56, 68-74.
52. Boufaïed, H., Chouinard, P. Y., Tremblay, G. F., Petit, H. V., et al., Fatty acids in forages. I. Factors affecting concentrations. Can. J. Animal Sci. 2003, 83, 501-511.
53. Walstra, P., Physical Chemistry of Foods, Marcel Dekker, Inc., New York 2003.
54. Frankel, E. N., Lipid Oxidation, The Oily Press, Dundee, UK 1998.
55. Witkowska, I. M., Wever, A. C., Elgersma, A., Effects of post-harvest treatments on concentrations and profile of fatty acids in fresh perennial ryegrass (Lolium perenne L.). Anim. Feed Sci. Techn. 2009, 149, 60-69.
56. Arvidsson, K., Gustavsson, A.-M., Martinsson, K., Fatty acids in forages: A comparison of different pre-treatments prior to analysis. Anim. Feed Sci. Technol. 2009, 151, 143-152.
57. Witkowska, I. M., Lourenço, M., Fievez, V., Arvidsson, K., et al., Current Advances in the Biochemistry and Cell Biology of Plant Lipids. Proceedings of the 17th International Symposium on Plant Lipids, Michigan State University, East Lansing, Michigan, USA, July 2006, Salt Lake City 2008.
58. Witkowska, I. M., Wever, A. C., Gort, G., Elgersma, A., Effects of nitrogen rate and regrowth interval on perennial ryegrass fatty acid content during the growing season. Agron. J. 2008, 100, 1371-1379.
59. Elgersma, A., Søegaard, K., Jensen, S. K., Fatty acids, α-tocopherol, β-carotene and lutein contents in forage legumes, forbs and a grass - clover mixture. J. Agric. Food Chem. 2013, 61, 11913-11920.
60. Wyss, U., Collomb, M., Fatty acid composition of different grassland species. Grassland Sci. Eur. 2010, 15, 631-633.
61. Clapham, W. M., Foster, J. G., Neel, J. P. S., Fedders, J. M., Fatty acid composition of traditional and novel forage species. J. Agric. Food Chem. 2005, 53, 10068-10073.
62. Warner, D., Jensen, S. K., Cone, J. W., Elgersma, A., Fatty acid composition of forage herb species. Grassl. Sci. Eur. 2010, 15, 491-493.
63. Wyss, U., Influence of conservation method on fatty acid composition of herbages of a permanent grassland meadow. Grassl. Sci. Eur. 2012, 17, 323-325.
64. Ranst, G. van, Fievez, V., Vandewalle, M., Riek, J. de, Bockstaele, E. van, Influence of herbage species, cultivar and cutting date on fatty acid composition of herbage and lipid metabolism during ensiling. Grass Forage Sci. 2009, 64, 169-207.
65. Palladino, R. A., O'Donovan, M., Kennedy, E., Murphy, J. J., et al., Fatty acid composition and nutritive value of twelve cultivars of perennial ryegrass. Grass Forage Sci. 2009, 64, 219-226.
66. Elgersma, A., Ellen, G., Dekker, R. G., Horst van der, H., et al., Effects of perennial ryegrass (Lolium perenne) cultivars with different linolenic acid contents on milk fatty acid composition. Aspects Appl. Biol. 2003, 20, 107-114.
67. Khan, N. A., Cone, J. W., Pellikaan, W. F., Khan, M. A., et al., Changes in fatty acid content and composition in silage maize during grain filling. J. Sci. Food Agric. 2011, 91, 1041-1049.
68. Khiaosa-ard, R., Klevenhusen, F., Soliva, C. R., Kreuzer, M., Leiber, F., Transfer of linoleic and linolenic acid from feed to milk in cows fed isoenergetic diets differing in proportion and origin of concentrates and roughages. J. Dairy Res. 2010, 77, 331-336.
69. Palmquist, D. L., Lock, A. L., Shingfield, K. J., Bauman, D. E., Biosynthesis of conjugated linoleic acid in ruminants and humans. Adv. Food Nutr. Res. 2005, 50, 179-217.
70. Jenkins, T. C., Wallace, R. J., Moate, P. J., Mosley, E. E., Board-invited review: Recent advances in biohydrogenation of unsaturated fatty acids within the rumen microbial ecosystem. J. Anim. Sci. 2008, 86, 397-412.
71. Bauman, D. E., Griinari, J. M., Regulation and nutritional manipulation of milk fat: Low-fat milk syndrome. Livest. Prod. Sci. 2001, 70, 15-29.
72. Elgersma, A., Tamminga, S., Ellen, G., Modifying milk composition through forage-A review. Animal Feed Sci. Techn. 2006, 131, 207-225.
73. Lee, M. R. F., Shingfield, K. J., Tweed, J. K. S., Toivonen, V., et al., Effect of fish oil on ruminal biohydrogenation of C18 unsaturated fatty acids in steers fed grass or red clover silages. Animal 2008, 2, 1859-1869.
74. Shingfield, K. J., Kairenius, P., Arola, A., Paillard, D., et al., Dietary fish oil supplements modify ruminal biohydrogenation, alter the flow of fatty acids at the omasum, and induce changes in the ruminal Butyrivibrio population in lactating cows. J. Nutr. 2012, 142, 1437-1448.
75. Lourenço, M., Ranst van, G., Vlaeminck, B., Smet de, S., Fievez, V., Influence of different dietary forages on the fatty acid composition of rumen digesta as well as ruminant meat and milk. Anim. Feed Sci. Technol. 2008, 145, 418-437.
76. Harvatine, K. J., Allen, M. S., Fat supplements affect fractional rates of ruminal fatty acid biohydrogenation and passage in dairy cows. J. Nutr. 2006, 136, 677-685.
77. Fuentes, M. C., Calsamiglia, S., Cardozo, P. W., Vlaeminck, B., Effect of pH and level of concentrate in the diet on the production of biohydrogenation intermediates in a dual-flow continuous culture. J. Dairy Sci. 2009, 92, 4456-4466.
78. Klieve, A. V., Hennessy, D., Ouwerkerk, D., Forster, R. J., et al., Establishing populations of Megasphaera elsdenii YE 34 and Butyrivibrio fibrisolvens YE 44 in the rumen of cattle fed high grain diets. J. Appl. Microbiol. 2003, 95, 621-630.
79. Nielsen, T. S., Straarup, E. M., Vestergaard, M., Sejrsen, K., Effect of silage type and concentrate level on conjugated linoleic acids, trans-C18: 1 isomers and fat content in milk from dairy cows. Reprod. Nutr. Dev. 2006, 46, 699-712.
80. Palmquist, D. L., Jenkins, T. C., Fat in lactation rations. Review. J. Dairy Sci 1980, 63, 1-14.
81. Hutton, K., Seeley, R. C., Armstrong, D. G., The variation throughout the year in the fatty acid composition of milk fat from 2 dairy herds. J. Dairy Res. 1969, 36, 103-113.
82. Hall, A. J., Seasonal and regional variation in the fatty acid composition of milk fat. Dairy Industry 1970, 35, 20-24.
83. Palmquist, D. L., in: Fox, P. L., McSweeney, H. (Eds.), Advanced dairy chemistry, vol. 2, Springer Science, New York 2006, pp. 43-92.
84. 9-desaturase activity in dairy cows. Livestock Prod Sci. 2003, 79, 47-59.
85. Wiking, L., Theil, P. K., Nielsen, J. H., Sorensen, M. T., Effect of grazing fresh legumes or feeding silage on fatty acids and enzymes involved in the synthesis of milk fat In dairy cows. J. Dairy Res. 2010, 77, 337-342.
86. Mattsson, S., Poly-unsaturated Fatty Acids in Butter and Their Influence on the Oxidation of Butter. Methods of Analysis and Preliminary Results. Proceedings of the XIIth International Dairy Congress, Section II, Stockholm 1949, pp. 308-324.
87. Stadhouders, J., Mulder, H., The composition of Dutch butterfat. 1. Seasonal variations in the unsaturated fatty acid composition of butter fat. Neth. Milk Dairy J. 1955, 9, 182-193.
88. Riel, R. R., Physico-chemical characteristics of Canadian milk fat. Unsaturated fatty acids. J. Dairy Sci. 1963, 46, 102-106.
89. Downey, L., Doyle, P. T., Cow nutrition and dairy product manufacture-implications of seasonal pasture-based milk production systems. Austr. J. Dairy Technol. 2007, 62, 3-11.
90. Agenas, S., Holtenius, K., Griinari, M., Burstedt, E., Effects of turnout to pasture and dietary fat supplementation on milk fat composition and conjugated linoleic acid in dairy cows. Animal Sci. 2002, 52, 25-33.
91. Khanal, R. C., Dhiman, T. R., Boman, R. L., Changes in fatty acid composition of milk from lactating dairy cows during transition to and from pasture. Livest. Sci. 2008, 114, 164-175.
92. Auldist, M. J., Walsh, B. J., Thomson, N. A., Seasonal and lactational influences on bovine milk composition in New Zealand. J. Dairy Res. 1998, 65, 401-411.
93. Elgersma, A., Wever, A. C., Nałecz-Tarwacka, T., Grazing versus indoor feeding: Effects on milk quality. Invited key note. Grassl. Sci. Eur. 2006, 11, 419-427.
94. Reklewska, B., Bernatowicz, E., Reklewski, Z., Nałecz-Tarwacka, T., et al., [Concentration of milk functional components in Black-and-White cows, depending on the season and feeding system] in Polish. Zeszyty Naukowe Przegladu Hodowlanego 2003, 68, 85-98.
95. Elgersma, A., Ellen, G., Horst van der, H., Muuse, B. G., Quick changes in milk fat composition after transition from fresh grass to a silage diet. Anim. Feed Sci. Techn. 2004, 117, 13-27.
96. Chilliard, Y., Ferlay, A., Doreau, M., Effect of different types of forages, animal fat or marine oils in cow's diet on milk fat secretion and composition, especially conjugated linoleic acid (CLA) and polyunsaturated fatty acids. Livest. Prod. Sci. 2001, 70, 31-48.
97. Kelly, M.L, Kolver, E. S., Bauman, D. E., Amburgh van, M. E., Muller, L. D., Effect of intake of pasture on concentrations of conjugated linoleic acid in milk of lactating cows. J. Dairy Sci. 1998, 81, 1630-1636.
98. White, S. L., Bertrand, J. A., Wade, M. R., Washburn, S. P., et al., Comparison of fatty acid content of milk from Jersey and Holstein cows consuming pasture or a total mixed ration. J. Dairy Sci. 2001, 84, 2295-2301.
99. Offer, N. W., in: Gechie, L.M., Thomas, C. (Eds.), Proceedings of the XIIIth International Silage Conference, Auchincruive, Scotland, Scottish Agricultural College, UK, 2002, pp. 16-17.
100. Elgersma, A., Tamminga, S., Ellen, G., Comparison of the effects of grazing and zero-grazing of grass on milk fatty acid composition of dairy cows. Grassl. Sci Eur. 2003, 8, 271-274.
101. Elgersma, A., Ellen, G., Tamminga, S., Rapid decline of contents of beneficial omega-7 fatty acids in milk from grazing cows with decreasing herbage allowance. Grassl. Sci. Eur. 2004, 9, 1136-1138.
102. Elgersma, A., Horst van der, H., Dekker, P. R., Ellen, G., Tamminga, S., No effects on milk fatty acid composition of perennial ryegrass cultivars with contrasting forage. Grassl. Sci. Eur. 2008, 13, 406-408.
103. Schroeder, G. F., Gagliostro, G. A., Bargo, F., Delahoy, J. E., Muller, L. D., Effects of fat supplementation on milk production and composition by dairy cows on pasture: A review. Livest. Prod Sci. 2004, 86, 1-18.
104. Stanton, C., Lawless, F., Kjellmer, G., Harrington, D., et al., Dietary influences on bovine milk cis-9, trans-11-conjugated linoleic acid content. J. Food Sci. 1997, 62, 1083-1086.
105. Stockdale, C. R., Walker, G. P., Wales, W. J., Dalley, D. E., et al., Influence of pasture and concentrates in the diet of grazing dairy cows on the fatty acid composition of milk. J. Dairy Res. 2003, 70, 267-276.
106. Bargo, F., Delahoy, J. E., Schroeder, G. F., Baumgard, L. H., Muller, L. D., Supplementing total mixed rations with pasture increase the content of conjugated linoleic acid in milk. An. Feed Sci. Techn. 2006, 131, 226-240.
107. Griinari, J. M., Nurmela, K., Sairanen, A., Nousiainen, J. I., Khalili, H., Effect of dietary sunflower oil and pasture forage maturity on conjugated linoleic acid (CLA) content in milk fat from lactating dairy cows. J. Dairy Sci. 1998, 81, 300.
108. Khanal, R. C., Olson, K. C., Factors affecting conjugated linoleic acid (CLA) content in milk, meat and egg: A review. Pakistan J. Nutr. 2004, 3, 82-98.
109. Elgersma, A., Hoeven van der, E., Witkowska, I. M., Smit, H. J., Effects of the grazed horizon in perennial ryegrass swards on the conjugated linoleic acid concentration in milk of dairy cows. Europe 2008, 13, 388-390.
110. Abrahamse, P. A., Dijkstra, J., Vlaeminck, B., Tamminga, S., Frequent allocation of rotationally grazed dairy cows changes grazing behavior and improves productivity. J. Dairy Sci. 2008, 91, 2033-2045.
111. Vlaeminck, B., Abrahamse, P. A., Fievez, V., Lourenco, M., et al., The effect of allocation frequency in rotational grazing systems on the fatty acid profile in milk fat of dairy cows. Grassl. Sci. Eur. 2010, 15, 586-588.
112. Dewhurst, R. J., Fisher, W. J., Tweed, J. K. S., Wilkins, R. J., Comparison of grass and legume silages for milk production. 1. Production responses with different levels of concentrate. J. Dairy Sci. 2003, 86, 2598-2611.
113. Höjer, A., Adler, S., Martinsson, K., Jensen, S. K., et al., Effect of legume-grass silages and α-tocopherol supplementation on fatty acid composition and α-tocopherol, β-carotene and retinol concentrationsinorganically produced bovine milk. Livest. Sci. 2012, 148, 268-281.
114. Halmemies-Beauchet-Filleau, A., Vanhatalo, A., Toivonen, V., Heikkilä, T., et al., in: Kuoppala, K., Rinne, M., Vanhatalo, A. (Eds.), Effect of replacing grass silage with red clover silage on rumen lipid metabolism and milk fatty acid composition, MTT Agrifood Research Finland, University of Helsinki, Finland 2012, pp. 40-41.
115. Lee, M. R. F., Winters, A. L., Scollan, N. D., Dewhurst, R. J., et al., Plant-mediated lipolysis and proteolysis in red clover with different polyphenol oxidase activities. J. Sci. Food Agric. 2004, 84, 1639-1645.
116. Collomb, M., Bütikofer, U., Sieber, R., Jeangros, B., Bosset, J. O., Correlation between fatty acids in cows' milk fat produced in the lowlands, mountains and highlands of Switzerland and botanical composition of the fodder. Int. Dairy J. 2002, 12, 661-666.
117. Larsen, M. K., Fretté, X. C., Kristensen, T., Eriksen, J., et al., Fatty acid, tocopherol and carotenoid content in herbage and milk affected by sward composition and season of grazing. J. Sci. Food Agric. 2012, 92, 2891-2898.
118. Soder, K. J., Sanderson, M. A., Stack, J. L., Muller, L. D., Intake and performance of lactating cows grazing diverse forage mixtures. J. Dairy Sci. 2006, 89, 2158-2167.
119. Adler, S. A., Dahl, A. V., Jensen, S. K., Thuen, E., et al., Fatty acid composition, fat-soluble vitamin concentrations and oxidative stability in bovine milk produced on two pastures with different botanical composition. Livest. Sci. 2013, 154, 93-102.
120. Loges, R., Urter og tanninrige planter - den nyeste tyske forskning. In: Plantekongres 2012-produktion, plan og miljø. Herning, Denmark 2012, pp. 363-365.
121. Petersen, M. B., Søegaard, K., Jensen, S. K., Herb feeding increases n-3 and n-6 fatty acids in cow milk. Livest. Sci. 2011, 141, 90-94.
122. Petersen, M. B., Jensen, S. K., Bohydrogenation of fatty acids is dependent on plant species and feeding regimen of dairy cows. J. Agric. Food Chem. 2014, 62, 3570-3576.
123. Choi, N., Park, H. G., Kim, J. H., Hwang, H., et al., Characterizations of environmental factors in conjugated linoleic acid production by mixed rumen bacteria. J. Agric. Food Chem. 2009, 57, 9263-9267.
124. Prati, S., Baravelli, V., Fabbri, D., Schwarzinger, C., et al., Composition and content of seen flavonoids in forages and grain legume crops. J. Sep. Sci. 2007, 30, 491-501.
125. Balcells, J., Aris, A., Serrano, A., Seradj, A. R., et al., Effect of an extract of plant flavonoids (Bioflavex) on rumen fermentation and performance in herifers fed high-concentrate diets. J. Anim. Sci. 2012, 90, 4975-4984.
126. - mice. Eur. J. Lipid Sci. Technol. 2011, 113, 572-583.
127. Griinari, J. M., Bauman, D. E., in: Yurawecz, M. P., Mossoba, M. M., Kramer, J. K. G., Pariza, M. W., Nelson, G. J. (Eds.), Advances in Conjugated Linoleic Acid Research, Vol. 1, AOCS Press, Champaign, IL 1999, pp. 180-200.
128. Piperova, L. S., Teter, B. B., Bruckental, I., Sampugna, J., et al., Mammary lipogenic enzyme activity, trans fatty acids and conjugated linoleic acids are altered in lactating dairy cows fed a milk fat-depressing diet. J. Nutr. 2000, 130, 2568-2574.
129. Cruz-Hernandez, C., Kramer, J. K. G., Kennelly, J. J., Sorensen, B. M., et al., Evaluating the CLA and trans 18:1 isomers in milk fat of dairy cows fed increasing amounts of sunflower oil and a constant level of fish oil. J. Dairy Sci. 2007, 90, 3786-3801.
130. Roy, A., Ferlay, A., Shingfield, K. J., Chilliard, Y., Examination of the persistency of milk fatty acid composition responses to plant oils in cows given different basal diets, with particular emphasis on trans-C18: 1 fatty acids and isomers of conjugated linoleic acid. Anim. Sci. 2006, 82, 479-492.
131. Gómez-Cortés, P., Frutos, P., Mantecón, A. R., Juárez, M., et al., Addition of olive oil to dairy ewe diets: Effect on milk fatty acid profile and animal performance. J. Dairy Sci. 2008, 91, 3119-3127.
132. Shingfield, K. J., Reynolds, C. K., Lupoli, B., Toivonen, V., et al., Effect of forage type and proportion of concentrate in the diet on milk fatty acid composition in cows given sunflower oil and fish oil. Anim. Sci. 2005, 80, 225-238.
133. Mohammed, R., Kennelly, J. J., Kramer, J. K. G., Beauchemin, K. A., et al., Effect of grain type and processing method on rumen fermentation and milk rumenic acid production. Animal 2010, 4, 1425-1444.
134. Hellgren, L. I., Phytanic acid-an overlooked bioactive fatty acid in dairy fat? Ann. NY Acad. Sci. 2010, 1190, 42-49.
135. Schroder, M., Yousefi, F., Vetter, W., Investigating the day-to-day variations of potential marker fatty acids for organic milk in milk from conventionally and organically raised cows. Eur. Food Res. Technol. 2011, 232, 167-174.
136. Baars, T., Schröder, M., Kusche, D., Vetter, W., Phytanic acid content and SRR/RRR diastereomer ratio in milk from organic and conventional farms at low and high level of fodder input. Org. Agric. 2012, 2, 13-21.
137. Che, B. N., Kristensen, T., Nebel, C., Dalsgaard, T. K., et al., Content and distribution of phytanic acid diastereomers in organic milk as affected by feed composition. J. Agric. Food Chem. 2013, 61, 225-230.
138. Vanhatalo, A., Kuoppala, K., Toivonen, V., Shingfield, K. J., Effects of forage species and stage of maturity on bovine milk fatty acid composition. Eur. J. Lipid Sci. Technol. 2007, 109, 856-867.
139. Schroder, M., Lutz, N. L., Tangwan, E. C., Hajazimi, E., Vetter, W., Phytanic acid concentrations and diastereomer ratios in milk fat during changes in the cow's feed from concentrate to hay and back. Eur. Food Res. Techn. 2012, 234, 955-962.
140. Leiber, F., Kreuzer, M., Nigg, D., Wettstein, H. R., Scheeder, M. R. L., A study on the causes for the elevated n-3 fatty acids in cows' milk of alpine origin. Lipids 2005, 40, 191-202.
141. Vetter, W., Schroder, M., Concentrations of phytanic acid and pristanic acid are higher in organic than in conventional dairy products from the German market. Food Chem. 2010, 119, 746-752.
142. Capuano, E., Elgersma, A., Tres, A., Ruth van, S. M., Phytanic and pristanic acid content in Dutch farm milk and implications for the verification of the farming management system. Int. Dairy J. 2014, 35, 21-24.
143. Alves, S. P., Bessa, R. J. B., The trans-10, cis-15 C18: 2: A missing intermediate of trans-10 shifted rumen biohydrogenation pathway? Lipids 2014, 49, 527-541.
144. Palupi, E., Jayanegara, A., Ploeger, A., Kahl, J., Comparison of nutritional quality between conventional and organic dairy products: A meta-analysis. J. Sci. Food Agric. 2012, 92, 2774-2781.
145. Butler, G., Nielsen, J. H., Slots, T., Seal, C., et al., Fatty acid and fat-soluble antioxidant concentrations in milk from high- and low-input conventional and organic systems: Seasonal variation. J. Sci. Food Agric. 2008, 88, 1431-1441.
146. Butler, G., Stergiadis, S., Seal, C., Eyre, M., Leifert, C., Fat composition of organic and conventional retail milk in northeast England. J. Dairy Sci. 2011, 94, 24-36.
147. Larsen, M. K., Nielsen, J. H., Butler, G., Leifert, C., et al., Milk quality as affected by feeding regimens in a country with climatic variation. J. Dairy Sci. 2010, 93, 2863-2873.
148. Hodgson, J., Grazing Management: Science into Practice. Longman handbooks in agriculture, Longman, Harlow (Essex, UK), 1990, pp. 203.
149. Haug, A., Hostmark, A. T., Harstad, O. M., Bovine milk in human nutrition-a review. Lipids Health Dis. 2007, 6, 25.
150. Elgersma, A., Ellen, G., Response from authors. Lipids 2004, 39, 695-696.
151. Wales, W. J., Doyle, P. T., Stockdale, C. R., Dellow, D. W., Effects of variation in herbage mass allowance and level of supplement on nutrient intake and milk production of dairy cows in spring and summer. Austr. J. Exper. Agric. 1999, 39, 119-131.
152. Stockdale, C. R., Differences in body condition and body size affect the responses of grazing dairy cows to high-energy supplements in early lactation. Austr. J. Exper. Agric. 2000, 40, 903-911.