Lovastatin production: From molecular basis to industrial process optimization

Biotechnology Advances

Volumn 33, Issue 6, 2015, Pages 648-665

  Mulder, Kelly C L ^a   Mulinari, Flávia ^a   Franco, Octávio L ^a   Soares, Maria S F ^a,b   Magalhães, Beatriz S ^a   Parachin, Nádia S ^a,b  

^a UNIVERSIDADE CATÓLICA DE BRASÍLIA   (Brazil)

^b INSTITUTO DE CIÊNCIAS BIOLÓGICAS   (Brazil)

Author keywords

Aspergillus terreus; HMG CoA inhibitors; Hypercholesterolemia; Lovastatin; Secondary metabolites

Indexed keywords

ANTIMICROBIAL AGENTS; ASPERGILLUS; BIOCHEMISTRY; BIOMOLECULES; BIOSYNTHESIS; DIAGNOSIS; DISEASES; ENZYMES; KETONES; OPTIMIZATION; PLANTS (BOTANY); PROCESS CONTROL;

ASPERGILLUS TERREUS; BIOSYNTHETIC PATHWAY; DETECTION AND QUANTIFICATIONS; HYPERCHOLESTEROLEMIA; LOVASTATIN; LOVASTATIN PRODUCTION; POLYKETIDE SYNTHASES; SECONDARY METABOLITES;

METABOLITES;

ANTIMICROBIAL ACTIVITY; BIOTECHNOLOGY; BLOOD SYSTEM DISORDER; BONE; CANCER; CARBON; DRUG; ENZYME ACTIVITY; FUNGUS; INHIBITION; NITROGEN; OPTIMIZATION; SECONDARY METABOLITE; SUBSTRATE;

ASPERGILLUS TERREUS; FUNGI;

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN;

ASPERGILLUS; CHEMISTRY; FERMENTATION; ISOLATION AND PURIFICATION; METABOLIC ENGINEERING; METABOLISM;

ASPERGILLUS; FERMENTATION; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LOVASTATIN; METABOLIC ENGINEERING;

EID: 84939270891     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2015.04.001     Document Type: Review

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