The statins fluvastatin and pravastatin exert anti-flushing effects by improving vasomotor dysfunction through nitric oxide-mediated mechanisms in ovariectomized animals

European Journal of Pharmacology

Volumn 651, Issue 1-3, 2011, Pages 234-239

  Shuto, Hideki ^a   Tominaga, Koji ^a   Yamauchi, Atsushi ^a   Ikeda, Munehiko ^a   Kusaba, Kenji ^a   Mitsunaga, Daisuke ^a   Hirabara, Yasutoshi ^a   Egawa, Takashi ^b   Takano, Yukio ^a   Kataoka, Yasufumi ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b SHUJITSU UNIVERSITY   (Japan)

Author keywords

Estrogen; Fluvastatin; Hot flush; Nitric oxide; Pravastatin; Vascular reactivity

Indexed keywords

ACETYLCHOLINE; ESTRADIOL VALERATE; FLUINDOSTATIN; NITRATE; NITRIC OXIDE; NITRITE; NITROPRUSSIDE SODIUM; PELANIN DEPOT; PHENYLEPHRINE; PRAVASTATIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; BODY WEIGHT; CONTROLLED STUDY; DRUG DOSE COMPARISON; EXERCISE; FEMALE; HOT FLUSH; MENOPAUSE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; SKIN TEMPERATURE; UTERUS WEIGHT; VASODILATATION; VASOMOTOR DISORDER;

ANIMALS; ARTERIES; BODY WEIGHT; ESTROGEN REPLACEMENT THERAPY; FATTY ACIDS, MONOUNSATURATED; FEMALE; HOT FLASHES; INDOLES; MENOPAUSE; MICE; NITRIC OXIDE; ORGAN SIZE; OVARIECTOMY; PHYSICAL CONDITIONING, ANIMAL; PRAVASTATIN; RATS; SKIN; UTERUS; VASOCONSTRICTION; VASODILATION; VASOMOTOR SYSTEM;

EID: 78650677876     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.10.084     Document Type: Article

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