Accelerated solvent extraction of monacolin K from red yeast rice and purification by high-speed counter-current chromatography

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 28, 2010, Pages 2881-2885

  Liu, Yuqin ^a,b   Guo, Xingfeng ^b   Duan, Wenjuan ^a   Wang, Xiao ^a   Du, Jinhua ^b  

^a QILU UNIVERSITY OF TECHNOLOGY   (China)

^b SHANDONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

Accelerated solvent extraction (ASE); High speed counter current chromatography (HSCCC); Monacolin K; Red yeast rice

Indexed keywords

ACCELERATED SOLVENT EXTRACTION; CHEMICAL STRUCTURE; CRUDE EXTRACT; CYCLE INDEX; ETHYL ACETATES; EXTRACTION CONDITIONS; EXTRACTION TEMPERATURES; EXTRACTION TIME; HIGH-SPEED COUNTER-CURRENT CHROMATOGRAPHY; ISOLATED COMPOUNDS; METHANOL-WATER; MONACOLIN K; N-HEXANE; OPTIMAL CONDITIONS; ORTHOGONAL TEST DESIGN; RED YEAST RICE; SEPARATION AND PURIFICATION; TWO-PHASE SOLVENT SYSTEM;

CHROMATOGRAPHY; ESTERS; HEXANE; METHANOL; OPTIMIZATION; ORGANIC SOLVENTS; PURIFICATION; SPEED; YEAST;

SOLVENT EXTRACTION;

ACETIC ACID ETHYL ESTER; CHOLESTIN; HEXANE; METHANOL; MEVINOLIN; WATER;

ARTICLE; COUNTER CURRENT CHROMATOGRAPHY; DRUG ISOLATION; DRUG PURIFICATION; DRUG PURITY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLVENT EXTRACTION; TEMPERATURE; TIME; ULTRAVIOLET SPECTROSCOPY;

ACETATES; BIOLOGICAL PRODUCTS; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUNTERCURRENT DISTRIBUTION; HEXANES; LOVASTATIN; METHANOL; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TEMPERATURE; TIME FACTORS;

EID: 77957314437     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.08.028     Document Type: Article

References (24)

1. Lin Y.L., Wang T.H., Lee M.H., Su N.W. Appl. Microbiol. Biotechnol. 2008, 77:965.
2. Ma J.Y., Li Y.G., Ye Q., Li J., Hua Y.J., Ju D.J., Zhang D.C., Cooper R., Chang M. J. Agric. Food Chem. 2000, 48:5220.
3. Li Y.G., Zhang F., Wang Z.T., Hu Z.B. J. Pharm. Biomed. Anal. 2004, 35:1101.
4. Journoud M., Jones P.J.H. Life Sci. 2004, 74:2675.
5. Devaraj S., Chan E., Jialal I. J. Clin. Endocrinol. Metab. 2006, 91:4489.
6. Endo A. J. Med. Chem. 1985, 28:401.
7. Hong M.Y., Seeram N.P., Zhang Y.J., Heber D. J. Nutr. Biochem. 2008, 19:448.
8. Hajjai H., Niederberger P., Duboc P. Appl. Environ. Microbiol. 2001, 67:2596.
9. Wang J.X., Lu Z.L., Chi J.M., Wang W.H., Su M.Z., Kou W.R., Yu P.L., Yu L.J., Chen L., Zhu J.H., Chang J. Curr. Ther. Res. 1997, 58:964.
10. Ahmad A., Panda B.P., Khan S., Ali M., Javed S. Thai J. Pharm. Sci. 2009, 33:39.
11. Handbook of Compositions from Crude Drug, Extraction, Separation and Purification 2002, 410. Chinese Traditional Medicine Press, Beijing. Y. Yang, J. Zhang, Y.T. Chen (Eds.).
12. Richer B.E., Jones B.A., Ezzell J.L., Porter N.L., Avdaovie N., Pohl C. Anal. Chem. 1996, 68:1033.
13. Schäfer K. Anal. Chim. Acta 1998, 358:69.
14. Shen J.C., Shao X.G. Anal. Bioanal. Chem. 2005, 383:1003.
15. Ibañez E., Herrero M., Martín-Álvarez P.J., Señoráns F.J., Reglero G., Cifuentes A. Am. Chem. Soc. 2006, 926:65.
16. Ito Y. J. Chromatogr. A 2005, 1065:145.
17. Wang X., Wang Y.Q., Yuan J.P., Sun Q.L., Liu J.H., Zheng C.C. J. Chromatogr. A 2004, 1055:135.
18. Ma C.H., Ke W., Sun Z.L., Peng J.Y., Li Z.X., Zhou X., Fan G.R., Huang C.G. Chromatographia 2006, 64:83.
19. Yao S., Liu R.M., Huang X.F., Kong L.Y. J. Chromatogr. A 2007, 1139:254.
20. Deng S.G., Deng Z.Y., Fan Y.W., Peng Y., Li J., Xiong D.M., Liu R. J. Chromatogr. B 2009, 877:2487.
21. Yanagida A., Shoji A., Shibusawa Y., Shindo H., Tagashira M., Ikeda M., Ito Y. J. Chromatogr. A 2006, 1112:195.
22. Guo X.F., Wang D.J., Duan W.J., Du J.H., Wang X. Phytochem. Anal. 2010, 21:268.
23. Du Q.Z., Xia M., Ito Y. J. Liq. Chromatogr. Rel. Technol. 2003, 26:3085.
24. Chen Y.P., Tseng C.P., Liaw L.L., Wang C.L., Chen I.C., Wu W.J., Wu M.D., Yuan G.F. J. Agric. Food Chem. 2008, 56:5639.