Influence of increased dissolved oxygen tensions by agitation on secondary metabolite production by a mutant of Aspergillus terreus in a 5L fermentor

Journal of the Chinese Institute of Chemical Engineers

Volumn 32, Issue 2, 2001, Pages 135-142

  Lai, L S T ^a   Kuo, C M ^a   Tsai, S Y ^a  

^a CHAOYANG UNIVERSITY OF TECHNOLOGY   (Taiwan)

Author keywords

Aspergillus terreus; Dissolved oxygen tension; Fermentations; Lovastatin; Secondary metabolites of fungi; Submerged fungal

Indexed keywords

SHAKING-FLASK DATA;

CELL CULTURE; CELLS; FERMENTATION; ORE PELLETS; OXYGEN; PH EFFECTS; SEED;

METABOLITES;

OXYGEN;

EID: 0035267544     PISSN: 03681653     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Dihydromevinolin, a potent hypocholes-terolemic metabolite produced by Aspergillus Terreus
2. Mycelial morphology and metabolite production
3. Drugs used in the treatment of Hyperlipoproteinemias
4. Production of Lovastatin, an inhibitor of cholesterol accumulation in humans
5. Secondary metabolism as an expression of microbial growth and development
6. Fermentation scale-up: Problems and possibilities
7. Biochemical and physiological characterization of the efrotomycin fermentation
8. Oxygen limitation can induce microbial secondary metabolite formation: Investigations with miniature electrodes in shaker and bioreactor bulture
9. Effect of agitation intensity on fungal morphology of submerged fermentation
10. Biosynthesis of ML-236B (Compactin) and monacolin K
11. High-performance liquid chromatography analysis of Mevinolin as Mevonolinic acid in fermentation broth
12. Interaction of cell morphology and transport process in the Lovastatin fermentation
13. Pleurotus fungi produce mevinolin, an inhibitor of HMG CoA reductase
14. Mevalonic acid biosynthesis by aspergillus terreus and its relationship to fatty acid biosynthesis
15. Scale-up of the efrotomycin fermentation using a computer-controlled pilot plant
16. Secondary metabolites of the fungus monascus: A review
17. Determination of Lovastatin (Mevinolin) and Mevinolinic acid in fermentation liquid
18. Effect of pH on the batch fermentation of pullulan from sucrose medium
19. 13 C NMR and mass spectrometry
20. Hyphal growth and fragmentation of Penicillium Chrysogenum in submerged cultures
21. Inhibition of the biosynthesis leucomycin, a macrolide antibiotic, by cerulenin
22. Polyketide Synthase Gene pksM expressed during growth phase
23. Biosynthesis of Mevinolin, a Hypocholesterolemic fungal Metabolite in Aspergillus Terreus
24. The effect of agitation on the morphology and penicillin production of Penicillium Chrysogenum
25. Mutants of a Lovastatin-Hyperproducing Aspergillus Terreus efficient in the production of Sulochrin
26. Investigations of oxygen transfer into Penicillium Chrysogenum pellets by microprobe measurements