Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers

Nucleic Acids Research

Volumn 42, Issue 20, 2014, Pages

  Gao, Xuefei ^a   Tsang, Jason C H ^a   Gaba, Fortis ^a   Wu, Donghai ^b   Lu, Liming ^a,c   Liu, Pentao ^a,d  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; HISTONE; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; TRANSCRIPTION FACTOR NANOG; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CRISPR CAS SYSTEM; EMBRYO; ENHANCER REGION; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE LOCUS; GENE REPRESSION; GENE TARGETING; INDUCED PLURIPOTENT STEM CELL; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; SOMATIC CELL; TRANSCRIPTION REGULATION; ANIMAL; BINDING COMPETITION; CELL CULTURE; COMPARATIVE STUDY; GENE LIBRARY; GENE VECTOR; GENETIC EPIGENESIS; GENETICS; METABOLISM; PLASMID; PLURIPOTENT STEM CELL; TRANSCRIPTION INITIATION;

ANIMALS; BINDING, COMPETITIVE; CELLS, CULTURED; CELLULAR REPROGRAMMING; CRISPR-ASSOCIATED PROTEINS; ENHANCER ELEMENTS, GENETIC; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; GENE LIBRARY; GENETIC VECTORS; INDUCED PLURIPOTENT STEM CELLS; MICE; OCTAMER TRANSCRIPTION FACTOR-3; PLASMIDS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84964313405     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku836     Document Type: Article

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