SCOPUS 정보 검색 플랫폼

Methods

Volumn 69, Issue 2, 2014, Pages 188-197

Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression

(2) Kabadi, Ami M a Gersbach, Charles A a,b,c

a Duke University (United States)

b DUKE UNIVERSITY (United States)

c DUKE UNIVERSITY MEDICAL CENTER (United States)

Author keywords

Cas9; CRISPR; Gene regulation; Gene therapy; Genetic reprogramming; Protein engineering; Synthetic biology; TAL effector; TALE; Transcription factor

Indexed keywords

DNA BINDING PROTEIN; GUIDE RNA; SYNTHETIC PEPTIDE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; TRANSCRIPTION FACTOR;

ARTICLE; BIOTECHNOLOGY; CRISPR CAS SYSTEM; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC ENGINEERING; GENETIC MANIPULATION; NONHUMAN; PRIORITY JOURNAL; REPRESSOR GENE; CHEMISTRY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENETICS; HUMAN; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES; PROTEIN SECONDARY STRUCTURE;

BASE SEQUENCE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-CAS SYSTEMS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; TRANSCRIPTION FACTORS;

EID: 84926410362 PISSN: 10462023 EISSN: 10959130 Source Type: Journal
DOI: 10.1016/j.ymeth.2014.06.014 Document Type: Article

Times cited : (33)

References (139)

1
- 84879264708
- Gaj T., Gersbach C.A., Barbas C.F. Trends Biotechnol. 2013, 31:397-405.
- (2013) Trends Biotechnol. , vol.31 , pp. 397-405
- Gaj, T.¹ Gersbach, C.A.² Barbas, C.F.³

2
- 77955867185
- Urnov F.D., et al. Nat. Rev. Genet. 2010, 11:636-646.
- (2010) Nat. Rev. Genet. , vol.11 , pp. 636-646
- Urnov, F.D.¹

3
- 84865297223
- Perez-Pinera P., Ousterout D.G., Gersbach C.A. Curr. Opin. Chem. Biol. 2012, 16:268-277.
- (2012) Curr. Opin. Chem. Biol. , vol.16 , pp. 268-277
- Perez-Pinera, P.¹ Ousterout, D.G.² Gersbach, C.A.³

4
- 84871519181
- Joung J.K., Sander J.D. Nat. Rev. Mol. Cell Biol. 2013, 14:49-55.
- (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 49-55
- Joung, J.K.¹ Sander, J.D.²

5
- 84875711728
- Gersbach C.A., Gaj T., Barbas C.F. Acc. Chem. Res. 2014.
- (2014) Acc. Chem. Res.
- Gersbach, C.A.¹ Gaj, T.² Barbas, C.F.³

6
- 0034652141
- Beerli R.R., Dreier B., Barbas C.F. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:1495-1500.
- (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 1495-1500
- Beerli, R.R.¹ Dreier, B.² Barbas, C.F.³

7
- 9444230573
- Blancafort P., Segal D.J., Barbas C.F. Mol. Pharmacol. 2004, 66:1361-1371.
- (2004) Mol. Pharmacol. , vol.66 , pp. 1361-1371
- Blancafort, P.¹ Segal, D.J.² Barbas, C.F.³

8
- 0032437591
- Beerli R.R., et al. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:14628-14633.
- (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 14628-14633
- Beerli, R.R.¹

9
- 0036912846
- Rebar E.J., et al. Nat. Med. 2002, 8:1427-1432.
- (2002) Nat. Med. , vol.8 , pp. 1427-1432
- Rebar, E.J.¹

10
- 13544277695
- Graslund T., et al. J. Biol. Chem. 2005, 280:3707-3714.
- (2005) J. Biol. Chem. , vol.280 , pp. 3707-3714
- Graslund, T.¹

11
- 77951060091
- Wilber A., et al. Blood 2010, 115:3033-3041.
- (2010) Blood , vol.115 , pp. 3033-3041
- Wilber, A.¹

12
- 0034089616
- Corbi N., et al. Gene Ther. 2000, 7:1076-1083.
- (2000) Gene Ther. , vol.7 , pp. 1076-1083
- Corbi, N.¹

13
- 77950540612
- Di Certo M.G., et al. Hum. Mol. Genet. 2010, 19:752-760.
- (2010) Hum. Mol. Genet. , vol.19 , pp. 752-760
- Di Certo, M.G.¹

14
- 84899750944
- Chapdelaine P., et al. Mol. Ther. Nucleic Acids 2013, 2:e119.
- (2013) Mol. Ther. Nucleic Acids , vol.2 , pp. e119
- Chapdelaine, P.¹

15
- 34247492871
- Beltran A., et al. Oncogene 2007, 26:2791-2798.
- (2007) Oncogene , vol.26 , pp. 2791-2798
- Beltran, A.¹

16
- 84901227909
- Strimpakos G., et al. J. Cell. Physiol. 2014, 229:1283-1291.
- (2014) J. Cell. Physiol. , vol.229 , pp. 1283-1291
- Strimpakos, G.¹

17
- 0142165907
- Bartsevich V.V., et al. Stem Cells 2003, 21:632-637.
- (2003) Stem Cells , vol.21 , pp. 632-637
- Bartsevich, V.V.¹

18
- 84863201964
- Bultmann S., et al. Nucleic Acids Res. 2012, 40:5368-5377.
- (2012) Nucleic Acids Res. , vol.40 , pp. 5368-5377
- Bultmann, S.¹

19
- 84881336110
- Gao X., et al. Stem Cell Reports 2013, 1:183-197.
- (2013) Stem Cell Reports , vol.1 , pp. 183-197
- Gao, X.¹

20
- 84890460786
- Kearns N.A., et al. Development 2014, 141:219-223.
- (2014) Development , vol.141 , pp. 219-223
- Kearns, N.A.¹

21
- 84867300642
- Garg A., et al. Nucleic Acids Res. 2012, 40:7584-7595.
- (2012) Nucleic Acids Res. , vol.40 , pp. 7584-7595
- Garg, A.¹

22
- 84870786425
- Li Y., et al. Sci. Rep. 2012, 2:897.
- (2012) Sci. Rep. , vol.2 , pp. 897
- Li, Y.¹

23
- 84864634066
- Khalil A.S., et al. Cell 2012, 150:647-658.
- (2012) Cell , vol.150 , pp. 647-658
- Khalil, A.S.¹

24
- 0036168937
- Beerli R.R., Barbas C.F. Nat. Biotechnol. 2002, 20:135-141.
- (2002) Nat. Biotechnol. , vol.20 , pp. 135-141
- Beerli, R.R.¹ Barbas, C.F.²

25
- 0035865250
- Tupler R., Perini G., Green M.R. Nature 2001, 409:832-833.
- (2001) Nature , vol.409 , pp. 832-833
- Tupler, R.¹ Perini, G.² Green, M.R.³

26
- 77953633943
- Klug A. Annu. Rev. Biochem. 2010, 79:213-231.
- (2010) Annu. Rev. Biochem. , vol.79 , pp. 213-231
- Klug, A.¹

27
- 84876352590
- Zhu C., et al. Nucleic Acids Res. 2013, 41:2455-2465.
- (2013) Nucleic Acids Res. , vol.41 , pp. 2455-2465
- Zhu, C.¹

28
- 84896731976
- Persikov A.V., et al. Nucleic Acids Res. 2014, 42:1497-1508.
- (2014) Nucleic Acids Res. , vol.42 , pp. 1497-1508
- Persikov, A.V.¹

29
- 47349097567
- Maeder M.L., et al. Mol. Cell 2008, 31:294-301.
- (2008) Mol. Cell , vol.31 , pp. 294-301
- Maeder, M.L.¹

30
- 42949083192
- Ramirez C.L., et al. Nat. Methods 2008, 5:374-375.
- (2008) Nat. Methods , vol.5 , pp. 374-375
- Ramirez, C.L.¹

31
- 79961202364
- Defrancesco L. Nat. Biotechnol. 2011, 29:681-684.
- (2011) Nat. Biotechnol. , vol.29 , pp. 681-684
- Defrancesco, L.¹

32
- 84882787078
- Pennisi E. Science 2013, 341:833-836.
- (2013) Science , vol.341 , pp. 833-836
- Pennisi, E.¹

33
- 72149090954
- Moscou M.J., Bogdanove A.J. Science 2009, 326:1501.
- (2009) Science , vol.326 , pp. 1501
- Moscou, M.J.¹ Bogdanove, A.J.²

34
- 72149110399
- Boch J., et al. Science 2009, 326:1509-1512.
- (2009) Science , vol.326 , pp. 1509-1512
- Boch, J.¹

35
- 79551685675
- Miller J.C., et al. Nat. Biotechnol. 2011, 29:143-148.
- (2011) Nat. Biotechnol. , vol.29 , pp. 143-148
- Miller, J.C.¹

36
- 79751487297
- Zhang F., et al. Nat. Biotechnol. 2011, 29:149-153.
- (2011) Nat. Biotechnol. , vol.29 , pp. 149-153
- Zhang, F.¹

37
- 79960064013
- Cermak T., et al. Nucleic Acids Res. 2011, 39:e82.
- (2011) Nucleic Acids Res. , vol.39 , pp. e82
- Cermak, T.¹

38
- 78951479577
- Christian M., et al. Genetics 2010, 186:757-761.
- (2010) Genetics , vol.186 , pp. 757-761
- Christian, M.¹

39
- 84860747716
- Reyon D., et al. Nat. Biotechnol. 2012, 30:460-465.
- (2012) Nat. Biotechnol. , vol.30 , pp. 460-465
- Reyon, D.¹

40
- 84874616818
- Perez-Pinera P., et al. Nat. Methods 2013, 10:239-242.
- (2013) Nat. Methods , vol.10 , pp. 239-242
- Perez-Pinera, P.¹

41
- 84874627289
- Maeder M.L., et al. Nat. Methods 2013, 10:243-245.
- (2013) Nat. Methods , vol.10 , pp. 243-245
- Maeder, M.L.¹

42
- 84865252679
- Tremblay J.P., et al. Hum. Gene Ther. 2012, 23:883-890.
- (2012) Hum. Gene Ther. , vol.23 , pp. 883-890
- Tremblay, J.P.¹

43
- 84865070369
- Jinek M., et al. Science 2012, 337:816-821.
- (2012) Science , vol.337 , pp. 816-821
- Jinek, M.¹

44
- 84873734105
- Mali P., et al. Science 2013, 339:823-826.
- (2013) Science , vol.339 , pp. 823-826
- Mali, P.¹

45
- 84873729095
- Cong L., et al. Science 2013, 339:819-823.
- (2013) Science , vol.339 , pp. 819-823
- Cong, L.¹

46
- 84876567971
- Jinek M., et al. Elife 2013, 2:e00471.
- (2013) Elife , vol.2 , pp. e00471
- Jinek, M.¹

47
- 84874624936
- Cho S.W., et al. Nat. Biotechnol. 2013, 31:230-232.
- (2013) Nat. Biotechnol. , vol.31 , pp. 230-232
- Cho, S.W.¹

48
- 84874617789
- Hwang W.Y., et al. Nat. Biotechnol. 2013, 31:227-229.
- (2013) Nat. Biotechnol. , vol.31 , pp. 227-229
- Hwang, W.Y.¹

49
- 84880571335
- Gilbert L.A., et al. Cell 2013, 154:442-451.
- (2013) Cell , vol.154 , pp. 442-451
- Gilbert, L.A.¹

50
- 84874687019
- Qi L.S., et al. Cell 2013, 152:1173-1183.
- (2013) Cell , vol.152 , pp. 1173-1183
- Qi, L.S.¹

51
- 84884906690
- Perez-Pinera P., et al. Nat. Methods 2013, 10:973-976.
- (2013) Nat. Methods , vol.10 , pp. 973-976
- Perez-Pinera, P.¹

52
- 84884907424
- Maeder M.L., et al. Nat. Methods 2013, 10:977-979.
- (2013) Nat. Methods , vol.10 , pp. 977-979
- Maeder, M.L.¹

53
- 84885180675
- Cheng A.W., et al. Cell Res. 2013, 23:1163-1171.
- (2013) Cell Res. , vol.23 , pp. 1163-1171
- Cheng, A.W.¹

54
- 84886488970
- Farzadfard F., Perli S.D., Lu T.K. ACS Synth. Biol. 2013, 2:604-613.
- (2013) ACS Synth. Biol. , vol.2 , pp. 604-613
- Farzadfard, F.¹ Perli, S.D.² Lu, T.K.³

55
- 84882976110
- Konermann S., et al. Nature 2013, 500:472-476.
- (2013) Nature , vol.500 , pp. 472-476
- Konermann, S.¹

56
- 84884160273
- Mali P., et al. Nat. Biotechnol. 2013, 31:833-838.
- (2013) Nat. Biotechnol. , vol.31 , pp. 833-838
- Mali, P.¹

57
- 84871666856
- A.Munoz Bodnar, et al. Mol. Biotechnol. 2013, 53:228-235.
- (2013) Mol. Biotechnol. , vol.53 , pp. 228-235
- Munoz Bodnar, A.¹

58
- 84863678546
- Streubel J., et al. Nat. Biotechnol. 2012, 30:593-595.
- (2012) Nat. Biotechnol. , vol.30 , pp. 593-595
- Streubel, J.¹

59
- 84857032466
- Deng D., et al. Science 2012, 335:720-723.
- (2012) Science , vol.335 , pp. 720-723
- Deng, D.¹

60
- 84857029597
- Mak A.N., et al. Science 2012, 335:716-719.
- (2012) Science , vol.335 , pp. 716-719
- Mak, A.N.¹

61
- 80053343092
- Bogdanove A.J., Voytas D.F. Science 2011, 333:1843-1846.
- (2011) Science , vol.333 , pp. 1843-1846
- Bogdanove, A.J.¹ Voytas, D.F.²

62
- 84857097177
- Wiedenheft B., Sternberg S.H., Doudna J.A. Nature 2012, 482:331-338.
- (2012) Nature , vol.482 , pp. 331-338
- Wiedenheft, B.¹ Sternberg, S.H.² Doudna, J.A.³

63
- 84886993480
- Larson M.H., et al. Nat. Protoc. 2013, 8:2180-2196.
- (2013) Nat. Protoc. , vol.8 , pp. 2180-2196
- Larson, M.H.¹

64
- 84877707375
- Wang H., et al. Cell 2013, 153:910-918.
- (2013) Cell , vol.153 , pp. 910-918
- Wang, H.¹

65
- 84884289608
- Yang H., et al. Cell 2013, 154:1370-1379.
- (2013) Cell , vol.154 , pp. 1370-1379
- Yang, H.¹

66
- 84883819602
- Li D., et al. Nat. Biotechnol. 2013, 31:681-683.
- (2013) Nat. Biotechnol. , vol.31 , pp. 681-683
- Li, D.¹

67
- 84884923061
- Chiu H., et al. Genetics 2013, 195:1167-1171.
- (2013) Genetics , vol.195 , pp. 1167-1171
- Chiu, H.¹

68
- 84884968656
- Tzur Y.B., et al. Genetics 2013, 195:1181-1185.
- (2013) Genetics , vol.195 , pp. 1181-1185
- Tzur, Y.B.¹

69
- 84876409836
- Chang N., et al. Cell Res. 2013, 23:465-472.
- (2013) Cell Res. , vol.23 , pp. 465-472
- Chang, N.¹

70
- 84874608929
- Jiang W., et al. Nat. Biotechnol. 2013, 31:233-239.
- (2013) Nat. Biotechnol. , vol.31 , pp. 233-239
- Jiang, W.¹

71
- 84887104139
- Esvelt K.M., et al. Nat. Methods 2013, 10:1116-1121.
- (2013) Nat. Methods , vol.10 , pp. 1116-1121
- Esvelt, K.M.¹

72
- 0038364114
- Gaston K., Jayaraman P.S. Cell. Mol. Life Sci. 2003, 60:721-741.
- (2003) Cell. Mol. Life Sci. , vol.60 , pp. 721-741
- Gaston, K.¹ Jayaraman, P.S.²

73
- 0028183182
- Margolin J.F., et al. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:4509-4513.
- (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 4509-4513
- Margolin, J.F.¹

74
- 0025920615
- Bellefroid E.J., et al. Proc. Natl. Acad. Sci. U.S.A. 1991, 88:3608-3612.
- (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 3608-3612
- Bellefroid, E.J.¹

75
- 2442536906
- Segal D.J., et al. J. Biol. Chem. 2004, 279:14509-14519.
- (2004) J. Biol. Chem. , vol.279 , pp. 14509-14519
- Segal, D.J.¹

76
- 0029858585
- Friedman J.R., et al. Genes Dev. 1996, 10:2067-2078.
- (1996) Genes Dev. , vol.10 , pp. 2067-2078
- Friedman, J.R.¹

77
- 0035957948
- Matsuda E., et al. J. Biol. Chem. 2001, 276:14222-14229.
- (2001) J. Biol. Chem. , vol.276 , pp. 14222-14229
- Matsuda, E.¹

78
- 0033013868
- Ryan R.F., et al. Mol. Cell. Biol. 1999, 19:4366-4378.
- (1999) Mol. Cell. Biol. , vol.19 , pp. 4366-4378
- Ryan, R.F.¹

79
- 0041624239
- Ayyanathan K., et al. Genes Dev. 2003, 17:1855-1869.
- (2003) Genes Dev. , vol.17 , pp. 1855-1869
- Ayyanathan, K.¹

80
- 33845935445
- Bulliard Y., et al. J. Biol. Chem. 2006, 281:35742-35746.
- (2006) J. Biol. Chem. , vol.281 , pp. 35742-35746
- Bulliard, Y.¹

81
- 77950421703
- Groner A.C., et al. PLoS Genet. 2010, 6:e1000869.
- (2010) PLoS Genet. , vol.6 , pp. e1000869
- Groner, A.C.¹

82
- 84864856835
- Cong L., et al. Nat. Commun. 2012, 3:968.
- (2012) Nat. Commun. , vol.3 , pp. 968
- Cong, L.¹

83
- 84881449454
- Crocker J., Stern D.L. Nat. Methods 2013, 10:762-767.
- (2013) Nat. Methods , vol.10 , pp. 762-767
- Crocker, J.¹ Stern, D.L.²

84
- 84855882014
- Mahfouz M.M., et al. Plant Mol. Biol. 2012, 78:311-321.
- (2012) Plant Mol. Biol. , vol.78 , pp. 311-321
- Mahfouz, M.M.¹

85
- 33745299723
- Grimm D., et al. Nature 2006, 441:537-541.
- (2006) Nature , vol.441 , pp. 537-541
- Grimm, D.¹

86
- 84882986957
- Bikard D., et al. Nucleic Acids Res. 2013, 41:7429-7437.
- (2013) Nucleic Acids Res. , vol.41 , pp. 7429-7437
- Bikard, D.¹

87
- 84901195977
- Nissim L., et al. Mol. Cell 2014, 54:698-710.
- (2014) Mol. Cell , vol.54 , pp. 698-710
- Nissim, L.¹

88
- 0037338381
- Blancafort P., Magnenat L., Barbas C.F. Nat. Biotechnol. 2003, 21:269-274.
- (2003) Nat. Biotechnol. , vol.21 , pp. 269-274
- Blancafort, P.¹ Magnenat, L.² Barbas, C.F.³

89
- 10744225041
- Park K.S., et al. Nat. Biotechnol. 2003, 21:1208-1214.
- (2003) Nat. Biotechnol. , vol.21 , pp. 1208-1214
- Park, K.S.¹

90
- 0027052876
- Seipel K., Georgiev O., Schaffner W. EMBO J. 1992, 11:4961-4968.
- (1992) EMBO J. , vol.11 , pp. 4961-4968
- Seipel, K.¹ Georgiev, O.² Schaffner, W.³

91
- 0023697252
- Sadowski I., et al. Nature 1988, 335:563-564.
- (1988) Nature , vol.335 , pp. 563-564
- Sadowski, I.¹

92
- 0026527184
- Ballard D.W., et al. Proc. Natl. Acad. Sci. U.S.A. 1992, 89:1875-1879.
- (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 1875-1879
- Ballard, D.W.¹

93
- 78650739853
- Morbitzer R., et al. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:21617-21622.
- (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 21617-21622
- Morbitzer, R.¹

94
- 84898998655
- Hu J., et al. Nucleic Acids Res. 2014, 42:4375-4390.
- (2014) Nucleic Acids Res. , vol.42 , pp. 4375-4390
- Hu, J.¹

95
- 84880570576
- Fu Y., et al. Nat. Biotechnol. 2013, 31:822-826.
- (2013) Nat. Biotechnol. , vol.31 , pp. 822-826
- Fu, Y.¹

96
- 84884165315
- Hsu P.D., et al. Nat. Biotechnol. 2013, 31:827-832.
- (2013) Nat. Biotechnol. , vol.31 , pp. 827-832
- Hsu, P.D.¹

97
- 84884155038
- Pattanayak V., et al. Nat. Biotechnol. 2013, 31:839-843.
- (2013) Nat. Biotechnol. , vol.31 , pp. 839-843
- Pattanayak, V.¹

98
- 84890091231
- Lamb B.M., Mercer A.C., Barbas C.F. Nucleic Acids Res. 2013, 41:9779-9785.
- (2013) Nucleic Acids Res. , vol.41 , pp. 9779-9785
- Lamb, B.M.¹ Mercer, A.C.² Barbas, C.F.³

99
- 79961185942
- Huang P., et al. Nat. Biotechnol. 2011, 29:699-700.
- (2011) Nat. Biotechnol. , vol.29 , pp. 699-700
- Huang, P.¹

100
- 0037372003
- Jaenisch R., Bird A. Nat. Genet. 2003, 33(Suppl.):245-254.
- (2003) Nat. Genet. , vol.33 , pp. 245-254
- Jaenisch, R.¹ Bird, A.²

101
- 84869046680
- Valton J., et al. J. Biol. Chem. 2012, 287:38427-38432.
- (2012) J. Biol. Chem. , vol.287 , pp. 38427-38432
- Valton, J.¹

102
- 84867095660
- Deng D., et al. Cell Res. 2012, 22:1502-1504.
- (2012) Cell Res. , vol.22 , pp. 1502-1504
- Deng, D.¹

103
- 84897954502
- Guilinger J.P., et al. Nat. Methods 2014, 11:429-435.
- (2014) Nat. Methods , vol.11 , pp. 429-435
- Guilinger, J.P.¹

104
- 84876557961
- Meckler J.F., et al. Nucleic Acids Res. 2013, 41:4118-4128.
- (2013) Nucleic Acids Res. , vol.41 , pp. 4118-4128
- Meckler, J.F.¹

105
- 84898942101
- Lin Y., et al. Nucleic Acids Res. 2014, 42:e47.
- (2014) Nucleic Acids Res. , vol.42 , pp. e47
- Lin, Y.¹

106
- 84898998318
- Fine E.J., et al. Nucleic Acids Res. 2014, 42:e42.
- (2014) Nucleic Acids Res. , vol.42 , pp. e42
- Fine, E.J.¹

107
- 84886084801
- Mendenhall E.M., et al. Nat. Biotechnol. 2013, 31:1133-1136.
- (2013) Nat. Biotechnol. , vol.31 , pp. 1133-1136
- Mendenhall, E.M.¹

108
- 84861170955
- Sanjana N.E., et al. Nat. Protoc. 2012, 7:171-192.
- (2012) Nat. Protoc. , vol.7 , pp. 171-192
- Sanjana, N.E.¹

109
- 84866879789
- Briggs A.W., et al. Nucleic Acids Res. 2012, 40:e117.
- (2012) Nucleic Acids Res. , vol.40 , pp. e117
- Briggs, A.W.¹

110
- 84872203111
- Schmid-Burgk J.L., et al. Nat. Biotechnol. 2013, 31:76-81.
- (2013) Nat. Biotechnol. , vol.31 , pp. 76-81
- Schmid-Burgk, J.L.¹

111
- 6344227879
- Tachikawa K., et al. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:15225-15230.
- (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 15225-15230
- Tachikawa, K.¹

112
- 84886043841
- Chen Z., et al. Nucleic Acids Res. 2013, 41:e182.
- (2013) Nucleic Acids Res. , vol.41 , pp. e182
- Chen, Z.¹

113
- 84864439768
- Gaj T., et al. Nat. Methods 2012, 9:805-807.
- (2012) Nat. Methods , vol.9 , pp. 805-807
- Gaj, T.¹

114
- 84901838361
- Liu J., et al. PLoS ONE 2014, 9:e85755.
- (2014) PLoS ONE , vol.9 , pp. e85755
- Liu, J.¹

115
- 84876389220
- Holkers M., et al. Nucleic Acids Res. 2013, 41:e63.
- (2013) Nucleic Acids Res. , vol.41 , pp. e63
- Holkers, M.¹

116
- 84885157177
- Yang L., et al. Nucleic Acids Res. 2013, 41:9049-9061.
- (2013) Nucleic Acids Res. , vol.41 , pp. 9049-9061
- Yang, L.¹

117
- 84895871173
- Sternberg S.H., et al. Nature 2014, 507:62-67.
- (2014) Nature , vol.507 , pp. 62-67
- Sternberg, S.H.¹

118
- 84891710947
- Cho S.W., et al. Genome Res. 2014, 24:132-141.
- (2014) Genome Res. , vol.24 , pp. 132-141
- Cho, S.W.¹

119
- 84896929630
- Fu Y., et al. Nat. Biotechnol. 2014, 32:279-284.
- (2014) Nat. Biotechnol. , vol.32 , pp. 279-284
- Fu, Y.¹

120
- 84880570576
- Fu Y., et al. Nat. Biotechnol. 2013, 31:822-826.
- (2013) Nat. Biotechnol. , vol.31 , pp. 822-826
- Fu, Y.¹

121
- 84884950106
- Cradick T.J., et al. Nucleic Acids Res. 2013, 41:9584-9592.
- (2013) Nucleic Acids Res. , vol.41 , pp. 9584-9592
- Cradick, T.J.¹

122
- 84902095352
- Wu X., et al. Nat. Biotechnol. 2014, 32:670-676.
- (2014) Nat. Biotechnol. , vol.32 , pp. 670-676
- Wu, X.¹

123
- 84903545084
- Kuscu C., et al. Nat. Biotechnol. 2014, 32:677-683.
- (2014) Nat. Biotechnol. , vol.32 , pp. 677-683
- Kuscu, C.¹

124
- 84896308706
- Bae S., Park J., Kim J.S. Bioinformatics 2014, 30:1473-1475.
- (2014) Bioinformatics , vol.30 , pp. 1473-1475
- Bae, S.¹ Park, J.² Kim, J.S.³

125
- 84893287073
- Heigwer F., Kerr G., Boutros M. Nat. Methods 2014, 11:122-123.
- (2014) Nat. Methods , vol.11 , pp. 122-123
- Heigwer, F.¹ Kerr, G.² Boutros, M.³

126
- 84904813279
- Montague T.G., et al. Nucleic Acids Res. 2014, 42:W401-W407.
- (2014) Nucleic Acids Res. , vol.42 , pp. W401-W407
- Montague, T.G.¹

127
- 84884663630
- Hou Z., et al. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:15644-15649.
- (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 15644-15649
- Hou, Z.¹

128
- 84894063115
- Chen B., et al. Cell 2013, 155:1479-1491.
- (2013) Cell , vol.155 , pp. 1479-1491
- Chen, B.¹

129
- 84875420616
- Maier D.A., et al. Hum. Gene Ther. 2013, 24:245-258.
- (2013) Hum. Gene Ther. , vol.24 , pp. 245-258
- Maier, D.A.¹

130
- 84864513068
- Eisenstein M. Nat. Biotechnol. 2012, 30:121-123.
- (2012) Nat. Biotechnol. , vol.30 , pp. 121-123
- Eisenstein, M.¹

131
- 33748329461
- Price S.A., et al. Diabetes 2006, 55:1847-1854.
- (2006) Diabetes , vol.55 , pp. 1847-1854
- Price, S.A.¹

132
- 84884856342
- Mali P., Esvelt K.M., Church G.M. Nat. Methods 2013, 10:957-963.
- (2013) Nat. Methods , vol.10 , pp. 957-963
- Mali, P.¹ Esvelt, K.M.² Church, G.M.³

133
- 84892765883
- Shalem O., et al. Science 2014, 343:84-87.
- (2014) Science , vol.343 , pp. 84-87
- Shalem, O.¹

134
- 84892749369
- Wang T., et al. Science 2014, 343:80-84.
- (2014) Science , vol.343 , pp. 80-84
- Wang, T.¹

135
- 84890048526
- Maeder M.L., et al. Nat. Biotechnol. 2013, 31:1137-1142.
- (2013) Nat. Biotechnol. , vol.31 , pp. 1137-1142
- Maeder, M.L.¹

136
- 84895832944
- Fonfara I., et al. Nucleic Acids Res. 2014, 42:2577-2590.
- (2014) Nucleic Acids Res. , vol.42 , pp. 2577-2590
- Fonfara, I.¹

137
- 0034693062
- Beerli R.R., et al. J. Biol. Chem. 2000, 275:32617-32627.
- (2000) J. Biol. Chem. , vol.275 , pp. 32617-32627
- Beerli, R.R.¹

138
- 84908451065
- Mercer A.C., et al. ACS Synth. Biol. 2013.
- (2013) ACS Synth. Biol.
- Mercer, A.C.¹

139
- 84867370333
- Polstein L.R., Gersbach C.A. J. Am. Chem. Soc. 2012, 134:16480-16483.
- (2012) J. Am. Chem. Soc. , vol.134 , pp. 16480-16483
- Polstein, L.R.¹ Gersbach, C.A.²

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