An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction

PLoS Pathogens

Volumn 11, Issue 7, 2015, Pages

  Minassian, Arlet ^a   Zhang, Junjie ^a   He, Shanping ^a   Zhao, Jun ^a   Zandi, Ebrahim ^a   Saito, Takeshi ^a   Liang, Chengyu ^a   Feng, Pinghui ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR; MITOCHONDRION ANTIVIRAL SIGNALING PROTEIN; MITOCHONDRION ANTIVIRAL SIGNALING PROTEIN 50; MITOCHONDRION ANTIVIRAL SIGNALING PROTEIN 70; PATTERN RECOGNITION RECEPTOR; PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; VIRUS PROTEIN; INTERFERON INDUCING AGENT; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN; VISA PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL FRACTIONATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL FILTRATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; LUCIFERASE ASSAY; NONHUMAN; PLAQUE ASSAY; PLASMID; PROTEIN INTERACTION; PROTEIN MOTIF; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSLATION INITIATION; VIRUS INFECTION; AMINO ACID SEQUENCE; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; HUMANS; INTERFERON INDUCERS; INTERFERONS; NF-KAPPA B; PROTEIN BINDING; TNF RECEPTOR-ASSOCIATED FACTOR 2; TNF RECEPTOR-ASSOCIATED FACTOR 6;

EID: 84938786868     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005060     Document Type: Article

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