Linear ubiquitination of NEMO negatively regulates the interferon antiviral response through disruption of the MAVS-TRAF3 complex

Cell Host and Microbe

Volumn 12, Issue 2, 2012, Pages 211-222

  Belgnaoui, S Mehdi ^a,b   Paz, Suzanne ^a   Samuel, Sara ^a,b   Goulet, Marie Line ^a   Sun, Qiang ^a   Kikkert, Marjolein ^c   Iwai, Kazuhiro ^d   Dikic, Ivan ^e   Hiscott, John ^a,b,f   Lin, Rongtuan ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d KYOTO UNIVERSITY   (Japan)

^e GOETHE UNIVERSITY MEDICAL SCHOOL   (Germany)

^f Vaccine and Gene Therapy Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; PROTEIN; PROTEIN SHARPIN; RETINOIC ACID INDUCIBLE PROTEIN I; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; VESICULAR STOMATITIS VIRUS; VIRUS REPLICATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; DOWN-REGULATION; HUMANS; I-KAPPA B KINASE; INTERFERONS; MICE; MICE, KNOCKOUT; PROTEIN BINDING; TNF RECEPTOR-ASSOCIATED FACTOR 3; UBIQUITINATION; VESICULAR STOMATITIS; VESICULAR STOMATITIS INDIANA VIRUS;

EID: 84865119303     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2012.06.009     Document Type: Article

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