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Volumn 4, Issue 9, 2008, Pages

Kaposi's sarcoma-associated herpesvirus K7 induces viral G protein-coupled receptor degradation and reduces its tumorigenicity

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; K7 PROTEIN; MEMBRANE PROTEIN; PROTEASOME; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 53049095670     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000157     Document Type: Article
Times cited : (25)

References (50)
  • 1
    • 0028588064 scopus 로고
    • Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
    • Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, et al. (1994) Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266: 1865-1869.
    • (1994) Science , vol.266 , pp. 1865-1869
    • Chang, Y.1    Cesarman, E.2    Pessin, M.S.3    Lee, F.4    Culpepper, J.5
  • 2
    • 17344385795 scopus 로고    scopus 로고
    • Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus
    • Lee H, Veazey R, Williams K, Li M, Guo J, et al. (1998) Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus. Nat Med 4: 435-440.
    • (1998) Nat Med , vol.4 , pp. 435-440
    • Lee, H.1    Veazey, R.2    Williams, K.3    Li, M.4    Guo, J.5
  • 3
    • 0029069445 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related bodycavity-based lymphomas
    • Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM (1995) Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related bodycavity-based lymphomas. N Engl J Med 332: 1186-1191.
    • (1995) N Engl J Med , vol.332 , pp. 1186-1191
    • Cesarman, E.1    Chang, Y.2    Moore, P.S.3    Said, J.W.4    Knowles, D.M.5
  • 4
    • 0029166033 scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease
    • Soulier J, Grollet L, Oksenhendler E, Cacoub P, Cazals-Hatem D, et al. (1995) Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 86: 1276-1280.
    • (1995) Blood , vol.86 , pp. 1276-1280
    • Soulier, J.1    Grollet, L.2    Oksenhendler, E.3    Cacoub, P.4    Cazals-Hatem, D.5
  • 5
    • 4344714976 scopus 로고    scopus 로고
    • Oncogenic gamma-herpesviruses: Comparison of viral proteins involved in tumorigenesis
    • Damania B (2004) Oncogenic gamma-herpesviruses: comparison of viral proteins involved in tumorigenesis. Nat Rev Microbiol 2: 656-668.
    • (2004) Nat Rev Microbiol , vol.2 , pp. 656-668
    • Damania, B.1
  • 6
    • 0033030061 scopus 로고    scopus 로고
    • Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposi's sarcoma (KS)-associated herpesvirus: Implications for KS pathogenesis
    • Kirshner JR, Staskus K, Haase A, Lagunoff M, Ganem D (1999) Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposi's sarcoma (KS)-associated herpesvirus: implications for KS pathogenesis. J Virol 73: 6006-6014.
    • (1999) J Virol , vol.73 , pp. 6006-6014
    • Kirshner, J.R.1    Staskus, K.2    Haase, A.3    Lagunoff, M.4    Ganem, D.5
  • 7
    • 0036118279 scopus 로고    scopus 로고
    • Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus
    • Chiou CJ, Poole LJ, Kim PS, Ciufo DM, Cannon JS, et al. (2002) Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus. J Virol 76: 3421-3439.
    • (2002) J Virol , vol.76 , pp. 3421-3439
    • Chiou, C.J.1    Poole, L.J.2    Kim, P.S.3    Ciufo, D.M.4    Cannon, J.S.5
  • 8
    • 0033615522 scopus 로고    scopus 로고
    • The N terminus of Kaposi's sarcomaassociated herpesvirus G protein-coupled receptor is necessary for high affinity chemokine binding but not for constitutive activity
    • Ho HH, Du D, Gershengorn MC (1999) The N terminus of Kaposi's sarcomaassociated herpesvirus G protein-coupled receptor is necessary for high affinity chemokine binding but not for constitutive activity. J Biol Chem 274: 31327-31332.
    • (1999) J Biol Chem , vol.274 , pp. 31327-31332
    • Ho1    HH, D.D.2    Gershengorn, M.C.3
  • 9
    • 0142213135 scopus 로고    scopus 로고
    • Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR
    • Bais C, Van Geelen A, Eroles P, Mutlu A, Chiozzini C, et al. (2003) Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR. Cancer Cell 3: 131-143.
    • (2003) Cancer Cell , vol.3 , pp. 131-143
    • Bais, C.1    Van Geelen, A.2    Eroles, P.3    Mutlu, A.4    Chiozzini, C.5
  • 10
    • 0035823485 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor signals through multiple pathways in endothelial cells
    • Couty JP, Geras-Raaka E, Weksler BB, Gershengorn MC (2001) Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor signals through multiple pathways in endothelial cells. J Biol Chem 276: 33805-33811.
    • (2001) J Biol Chem , vol.276 , pp. 33805-33811
    • Couty, J.P.1    Geras-Raaka, E.2    Weksler, B.B.3    Gershengorn, M.C.4
  • 11
    • 1242342108 scopus 로고    scopus 로고
    • Galpha protein selectivity determinant specified by a viral chemokine receptor-conserved region in the C tail of the human herpesvirus 8 g protein-coupled receptor
    • Liu C, Sandford G, Fei G, Nicholas J (2004) Galpha protein selectivity determinant specified by a viral chemokine receptor-conserved region in the C tail of the human herpesvirus 8 g protein-coupled receptor. J Virol 78: 2460-2471.
    • (2004) J Virol , vol.78 , pp. 2460-2471
    • Liu, C.1    Sandford, G.2    Fei, G.3    Nicholas, J.4
  • 12
    • 7244242279 scopus 로고    scopus 로고
    • The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia
    • Montaner S, Sodhi A, Servitja JM, Ramsdell AK, Barac A, et al. (2004) The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia. Blood 104: 2903-2911.
    • (2004) Blood , vol.104 , pp. 2903-2911
    • Montaner, S.1    Sodhi, A.2    Servitja, J.M.3    Ramsdell, A.K.4    Barac, A.5
  • 13
    • 0842286712 scopus 로고    scopus 로고
    • The KSHV G protein-coupled receptor signals via multiple pathways to induce transcription factor activation in primary effusion lymphoma cells
    • Cannon ML, Cesarman E (2004) The KSHV G protein-coupled receptor signals via multiple pathways to induce transcription factor activation in primary effusion lymphoma cells. Oncogene 23: 514-523.
    • (2004) Oncogene , vol.23 , pp. 514-523
    • Cannon, M.L.1    Cesarman, E.2
  • 14
    • 1842687489 scopus 로고    scopus 로고
    • Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor
    • Sodhi A, Montaner S, Patel V, Gomez-Roman JJ, Li Y, et al. (2004) Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor. Proc Natl Acad Sci U S A 101: 4821-4826.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4821-4826
    • Sodhi, A.1    Montaner, S.2    Patel, V.3    Gomez-Roman, J.J.4    Li, Y.5
  • 15
    • 33746832011 scopus 로고    scopus 로고
    • The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor
    • Sodhi A, Chaisuparat R, Hu J, Ramsdell AK, Manning BD, et al. (2006) The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. Cancer Cell 10: 133-143.
    • (2006) Cancer Cell , vol.10 , pp. 133-143
    • Sodhi, A.1    Chaisuparat, R.2    Hu, J.3    Ramsdell, A.K.4    Manning, B.D.5
  • 16
    • 0034614888 scopus 로고    scopus 로고
    • Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma
    • Yang TY, Chen SC, Leach MW, Manfra D, Homey B, et al. (2000) Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma. J Exp Med 191: 445-454.
    • (2000) J Exp Med , vol.191 , pp. 445-454
    • Yang, T.Y.1    Chen, S.C.2    Leach, M.W.3    Manfra, D.4    Homey, B.5
  • 17
    • 0037772150 scopus 로고    scopus 로고
    • Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes
    • Montaner S, Sodhi A, Molinolo A, Bugge TH, Sawai ET, et al. (2003) Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes. Cancer Cell 3: 23-36.
    • (2003) Cancer Cell , vol.3 , pp. 23-36
    • Montaner, S.1    Sodhi, A.2    Molinolo, A.3    Bugge, T.H.4    Sawai, E.T.5
  • 18
    • 0035667560 scopus 로고    scopus 로고
    • Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity
    • Holst PJ, Rosenkilde MM, Manfra D, Chen SC, Wiekowski MT, et al. (2001) Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity. J Clin Invest 108: 1789-1796.
    • (2001) J Clin Invest , vol.108 , pp. 1789-1796
    • Holst, P.J.1    Rosenkilde, M.M.2    Manfra, D.3    Chen, S.C.4    Wiekowski, M.T.5
  • 19
    • 0037213288 scopus 로고    scopus 로고
    • The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor has broad signaling effects in primary effusion lymphoma cells
    • Cannon M, Philpott NJ, Cesarman E (2003) The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor has broad signaling effects in primary effusion lymphoma cells. J Virol 77: 57-67.
    • (2003) J Virol , vol.77 , pp. 57-67
    • Cannon, M.1    Philpott, N.J.2    Cesarman, E.3
  • 20
    • 0035881482 scopus 로고    scopus 로고
    • Expression of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor monocistronic and bicistronic transcripts in primary effusion lymphomas
    • Nador RG, Milligan LL, Flore O, Wang X, Arvanitakis L, et al. (2001) Expression of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor monocistronic and bicistronic transcripts in primary effusion lymphomas. Virology 287: 62-70.
    • (2001) Virology , vol.287 , pp. 62-70
    • Nador, R.G.1    Milligan, L.L.2    Flore, O.3    Wang, X.4    Arvanitakis, L.5
  • 21
    • 0034915764 scopus 로고    scopus 로고
    • Mechanisms underlying ubiquitination
    • Pickart CM (2001) Mechanisms underlying ubiquitination. Annu Rev Biochem 70: 503-533.
    • (2001) Annu Rev Biochem , vol.70 , pp. 503-533
    • Pickart, C.M.1
  • 22
    • 26244439658 scopus 로고    scopus 로고
    • Viral modulation of antigen presentation: Manipulation of cellular targets in the ER and beyond
    • Lilley BN, Ploegh HL (2005) Viral modulation of antigen presentation: manipulation of cellular targets in the ER and beyond. Immunol Rev 207: 126-144.
    • (2005) Immunol Rev , vol.207 , pp. 126-144
    • Lilley, B.N.1    Ploegh, H.L.2
  • 23
    • 3042616595 scopus 로고    scopus 로고
    • A membrane protein required for dislocation of misfolded proteins from the ER
    • Lilley BN, Ploegh HL (2004) A membrane protein required for dislocation of misfolded proteins from the ER. Nature 429: 834-840.
    • (2004) Nature , vol.429 , pp. 834-840
    • Lilley, B.N.1    Ploegh, H.L.2
  • 24
    • 3042677637 scopus 로고    scopus 로고
    • A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
    • Ye Y, Shibata Y, Yun C, Ron D, Rapoport TA (2004) A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature 429: 841-847.
    • (2004) Nature , vol.429 , pp. 841-847
    • Ye, Y.1    Shibata, Y.2    Yun, C.3    Ron, D.4    Rapoport, T.A.5
  • 25
    • 1942486364 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus K7 protein targets a ubiquitin-like/ubiquitin- associated domain-containing protein to promote protein degradation
    • Feng P, Scott CW, Cho NH, Nakamura H, Chung YH, et al. (2004) Kaposi's sarcoma-associated herpesvirus K7 protein targets a ubiquitin-like/ubiquitin- associated domain-containing protein to promote protein degradation. Mol Cell Biol 24: 3938-3948.
    • (2004) Mol Cell Biol , vol.24 , pp. 3938-3948
    • Feng, P.1    Scott, C.W.2    Cho, N.H.3    Nakamura, H.4    Chung, Y.H.5
  • 26
    • 0036827974 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus mitochondrial K7 protein targets a cellular calcium-modulating cyclophilin ligand to modulate intracellular calcium concentration and inhibit apoptosis
    • Feng P, Park J, Lee BS, Lee SH, Bram RJ, et al. (2002) Kaposi's sarcoma-associated herpesvirus mitochondrial K7 protein targets a cellular calcium-modulating cyclophilin ligand to modulate intracellular calcium concentration and inhibit apoptosis. J Virol 76: 11491-11504.
    • (2002) J Virol , vol.76 , pp. 11491-11504
    • Feng, P.1    Park, J.2    Lee, B.S.3    Lee, S.H.4    Bram, R.J.5
  • 27
    • 0037013894 scopus 로고    scopus 로고
    • Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcomaassociated herpesvirus which resembles a spliced variant of human survivin
    • Wang HW, Sharp TV, Koumi A, Koentges G, Boshoff C (2002) Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcomaassociated herpesvirus which resembles a spliced variant of human survivin. EMBO J 21: 2602-2615.
    • (2002) EMBO J , vol.21 , pp. 2602-2615
    • Wang, H.W.1    Sharp, T.V.2    Koumi, A.3    Koentges, G.4    Boshoff, C.5
  • 28
    • 30844443758 scopus 로고    scopus 로고
    • Herpesviral protein networks and their interaction with the human proteome
    • Uetz P, Dong YA, Zeretzke C, Atzler C, Baiker A, et al. (2006)Herpesviral protein networks and their interaction with the human proteome. Science 311: 239-242.
    • (2006) Science , vol.311 , pp. 239-242
    • Uetz, P.1    Dong, Y.A.2    Zeretzke, C.3    Atzler, C.4    Baiker, A.5
  • 29
    • 1842509993 scopus 로고    scopus 로고
    • Concurrent expression of latent and a limited number of lytic genes with immune modulation and antiapoptotic function by Kaposi's sarcoma-associated herpesvirus early during infection of primary endothelial and fibroblast cells and subsequent decline of lytic gene expression
    • Krishnan HH, Naranatt PP, Smith MS, Zeng L, Bloomer C, et al. (2004) Concurrent expression of latent and a limited number of lytic genes with immune modulation and antiapoptotic function by Kaposi's sarcoma-associated herpesvirus early during infection of primary endothelial and fibroblast cells and subsequent decline of lytic gene expression. J Virol 78: 3601-3620.
    • (2004) J Virol , vol.78 , pp. 3601-3620
    • Krishnan, H.H.1    Naranatt, P.P.2    Smith, M.S.3    Zeng, L.4    Bloomer, C.5
  • 30
    • 0037377723 scopus 로고    scopus 로고
    • Global changes in Kaposi's sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivator
    • Nakamura H, Lu M, Gwack Y, Souvlis J, Zeichner SL, et al. (2003) Global changes in Kaposi's sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivator. J Virol 77: 4205-4220.
    • (2003) J Virol , vol.77 , pp. 4205-4220
    • Nakamura, H.1    Lu, M.2    Gwack, Y.3    Souvlis, J.4    Zeichner, S.L.5
  • 31
    • 0034742155 scopus 로고    scopus 로고
    • Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: Evidence for a paracrine model of Kaposi's sarcoma pathogenesis
    • Pati S, Cavrois M, Guo HG, Foulke JS Jr, Kim J, et al. (2001) Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesis. J Virol 75: 8660-8673.
    • (2001) J Virol , vol.75 , pp. 8660-8673
    • Pati, S.1    Cavrois, M.2    Guo, H.G.3    Foulke Jr, J.S.4    Kim, J.5
  • 32
    • 0037695122 scopus 로고    scopus 로고
    • Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat
    • Pati S, Foulke JS Jr, Barabitskaya O, Kim J, Nair BC, et al. (2003) Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat. J Virol 77: 5759-5773.
    • (2003) J Virol , vol.77 , pp. 5759-5773
    • Pati, S.1    Foulke Jr, J.S.2    Barabitskaya, O.3    Kim, J.4    Nair, B.C.5
  • 34
    • 0031032769 scopus 로고    scopus 로고
    • Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation
    • Arvanitakis L, Geras-Raaka E, Varma A, Gershengorn MC, Cesarman E (1997) Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation. Nature 385: 347-350.
    • (1997) Nature , vol.385 , pp. 347-350
    • Arvanitakis, L.1    Geras-Raaka, E.2    Varma, A.3    Gershengorn, M.C.4    Cesarman, E.5
  • 35
    • 33748336259 scopus 로고    scopus 로고
    • Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis
    • Maussang D, Verzijl D, van Walsum M, Leurs R, Holl J, et al. (2006) Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis. Proc Natl Acad Sci U S A 103: 13068-13073.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 13068-13073
    • Maussang, D.1    Verzijl, D.2    van Walsum, M.3    Leurs, R.4    Holl, J.5
  • 36
    • 0034645063 scopus 로고    scopus 로고
    • Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation
    • Mah AL, Perry G, Smith MA, Monteiro MJ (2000) Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation. J Cell Biol 151: 847-862.
    • (2000) J Cell Biol , vol.151 , pp. 847-862
    • Mah, A.L.1    Perry, G.2    Smith, M.A.3    Monteiro, M.J.4
  • 37
    • 17944363387 scopus 로고    scopus 로고
    • GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitinlike protein Plic-1
    • Bedford FK, Kittler JT, Muller E, Thomas P, Uren JM, et al. (2001) GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitinlike protein Plic-1. Nat Neurosci 4: 908-916.
    • (2001) Nat Neurosci , vol.4 , pp. 908-916
    • Bedford, F.K.1    Kittler, J.T.2    Muller, E.3    Thomas, P.4    Uren, J.M.5
  • 38
    • 26244431960 scopus 로고    scopus 로고
    • Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane
    • Lilley BN, Ploegh HL (2005) Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane. Proc Natl Acad Sci U S A 102: 14296-14301.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 14296-14301
    • Lilley, B.N.1    Ploegh, H.L.2
  • 39
    • 33646846643 scopus 로고    scopus 로고
    • The viral E3 ubiquitin ligase mK3 uses the Derlin/p97 endoplasmic reticulum-associated degradation pathway to mediate down-regulation of major histocompatibility complex class I proteins
    • Wang X, Ye Y, Lencer W, Hansen TH (2006) The viral E3 ubiquitin ligase mK3 uses the Derlin/p97 endoplasmic reticulum-associated degradation pathway to mediate down-regulation of major histocompatibility complex class I proteins. J Biol Chem 281: 8636-8644.
    • (2006) J Biol Chem , vol.281 , pp. 8636-8644
    • Wang, X.1    Ye, Y.2    Lencer, W.3    Hansen, T.H.4
  • 40
    • 0032583452 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus (KSHV) chemokine vMIP-II and human SDF-1alpha inhibit signaling by KSHV G protein-coupled receptor
    • Geras-Raaka E, Varma A, Clark-Lewis I, Gershengorn MC (1998) Kaposi's sarcoma-associated herpesvirus (KSHV) chemokine vMIP-II and human SDF-1alpha inhibit signaling by KSHV G protein-coupled receptor. Biochem Biophys Res Commun 253: 725-727.
    • (1998) Biochem Biophys Res Commun , vol.253 , pp. 725-727
    • Geras-Raaka, E.1    Varma, A.2    Clark-Lewis, I.3    Gershengorn, M.C.4
  • 41
    • 0026722655 scopus 로고
    • Cooperative interaction between c-myc and bcl-2 proto-oncogenes
    • Fanidi A, Harrington EA, Evan GI (1992) Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature 359: 554-556.
    • (1992) Nature , vol.359 , pp. 554-556
    • Fanidi, A.1    Harrington, E.A.2    Evan, G.I.3
  • 42
    • 33847619373 scopus 로고    scopus 로고
    • In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: A cell and animal model of virally induced Kaposi's sarcoma
    • Mutlu AD, Cavallin LE, Vincent L, Chiozzini C, Eroles P, et al. (2007) In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma. Cancer Cell 11: 245-258.
    • (2007) Cancer Cell , vol.11 , pp. 245-258
    • Mutlu, A.D.1    Cavallin, L.E.2    Vincent, L.3    Chiozzini, C.4    Eroles, P.5
  • 43
    • 0031937076 scopus 로고    scopus 로고
    • G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator
    • Bais C, Santomasso B, Coso O, Arvanitakis L, Raaka EG, et al. (1998) G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature 391: 86-89.
    • (1998) Nature , vol.391 , pp. 86-89
    • Bais, C.1    Santomasso, B.2    Coso, O.3    Arvanitakis, L.4    Raaka, E.G.5
  • 44
    • 0034614893 scopus 로고    scopus 로고
    • Viral G protein-coupled receptor and Kaposi's sarcoma: A model of paracrine neoplasia?
    • Cesarman E, Mesri EA, Gershengorn MC (2000) Viral G protein-coupled receptor and Kaposi's sarcoma: a model of paracrine neoplasia? J Exp Med 191: 417-422.
    • (2000) J Exp Med , vol.191 , pp. 417-422
    • Cesarman, E.1    Mesri, E.A.2    Gershengorn, M.C.3
  • 45
    • 33749184798 scopus 로고    scopus 로고
    • Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway
    • Denoyelle C, Abou-Rjaily G, Bezrookove V, Verhaegen M, Johnson TM, et al. (2006) Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. Nat Cell Biol 8: 1053-1063.
    • (2006) Nat Cell Biol , vol.8 , pp. 1053-1063
    • Denoyelle, C.1    Abou-Rjaily, G.2    Bezrookove, V.3    Verhaegen, M.4    Johnson, T.M.5
  • 46
    • 0000565101 scopus 로고    scopus 로고
    • Ras-dependent apoptosis correlates with persistent activation of stress-activated protein kinases and induction of isoform(s) of Bcl-x
    • Yu K, Chen YN, Ravera CP, Bayona W, Nalin CM, et al. (1997) Ras-dependent apoptosis correlates with persistent activation of stress-activated protein kinases and induction of isoform(s) of Bcl-x. Cell Death Differ 4: 745-755.
    • (1997) Cell Death Differ , vol.4 , pp. 745-755
    • Yu, K.1    Chen, Y.N.2    Ravera, C.P.3    Bayona, W.4    Nalin, C.M.5
  • 47
    • 37549054098 scopus 로고    scopus 로고
    • Desensitization of herpesvirus-encoded G protein-coupled receptors
    • Sherrill JD, Miller WE (2008) Desensitization of herpesvirus-encoded G protein-coupled receptors. Life Sci 82: 125-134.
    • (2008) Life Sci , vol.82 , pp. 125-134
    • Sherrill, J.D.1    Miller, W.E.2
  • 48
    • 0032473557 scopus 로고    scopus 로고
    • Inhibition of constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor by protein kinases in mammalian cells in culture
    • Geras-Raaka E, Arvanitakis L, Bais C, Cesarman E, Mesri EA, et al. (1998) Inhibition of constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor by protein kinases in mammalian cells in culture. J Exp Med 187: 801-806.
    • (1998) J Exp Med , vol.187 , pp. 801-806
    • Geras-Raaka, E.1    Arvanitakis, L.2    Bais, C.3    Cesarman, E.4    Mesri, E.A.5
  • 49
    • 38049069826 scopus 로고    scopus 로고
    • A Novel Inhibitory Mechanism of Mitochondrion-Dependent Apoptosis by a Herpesviral Protein
    • doi: 10.1371/journal.ppat.0030174
    • Feng P, Liang C, Shin YC, E X, Zhang W, et al. (2007) A Novel Inhibitory Mechanism of Mitochondrion-Dependent Apoptosis by a Herpesviral Protein. PLoS Pathog 3: e174. doi: 10.1371/journal.ppat.0030174.
    • (2007) PLoS Pathog , vol.3
    • Feng, P.1    Liang, C.2    Shin3    YC, E.X.4    Zhang, W.5
  • 50
    • 33745751085 scopus 로고    scopus 로고
    • Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
    • Liang C, Feng P, Ku B, Dotan I, Canaani D, et al. (2006) Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 8: 688-699.
    • (2006) Nat Cell Biol , vol.8 , pp. 688-699
    • Liang, C.1    Feng, P.2    Ku, B.3    Dotan, I.4    Canaani, D.5


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