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Volumn 52, Issue 1, 2015, Pages 399-413

The Role of PICALM in Alzheimer’s Disease

Author keywords

Alzheimer s disease; Amyloid beta; Genetics; Mechanism; PICALM; Polymorphism

Indexed keywords

AMYLOID BETA PROTEIN; CLATHRIN ASSEMBLY PROTEIN; PHOSPHATIDYLINOSITOL BINDING CLATHRIN ASSEMBLY PROTEIN; UNCLASSIFIED DRUG;

EID: 84937874784     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-014-8878-3     Document Type: Review
Times cited : (78)

References (136)
  • 1
    • 77953448164 scopus 로고    scopus 로고
    • Genetics of Alzheimer’s disease: recent advances
    • PID: 19341505
    • Avramopoulos D (2009) Genetics of Alzheimer’s disease: recent advances. Genome Med 1(3):34. doi:10.1186/gm34
    • (2009) Genome Med , vol.1 , Issue.3 , pp. 34
    • Avramopoulos, D.1
  • 2
    • 84888062913 scopus 로고    scopus 로고
    • Epidemiology and etiology of Alzheimer’s disease: from genetic to non-genetic factors
    • COI: 1:CAS:528:DC%2BC3sXhsFKktLzE, PID: 23919770
    • Jiang T, Yu JT, Tian Y, Tan L (2013) Epidemiology and etiology of Alzheimer’s disease: from genetic to non-genetic factors. Curr Alzheimer Res 10(8):852–867
    • (2013) Curr Alzheimer Res , vol.10 , Issue.8 , pp. 852-867
    • Jiang, T.1    Yu, J.T.2    Tian, Y.3    Tan, L.4
  • 3
    • 84907999361 scopus 로고    scopus 로고
    • Midlife vascular risk factors and the risk of Alzheimer’s disease: a systematic review and meta-analysis
    • Meng XF, Yu JT, Wang HF, Tan MS, Wang C, Tan CC, Tan L (2014) Midlife vascular risk factors and the risk of Alzheimer’s disease: a systematic review and meta-analysis. J Alzheimer’s Dis JAD. doi:10.3233/JAD-140954
    • (2014) J Alzheimer’s Dis JAD
    • Meng, X.F.1    Yu, J.T.2    Wang, H.F.3    Tan, M.S.4    Wang, C.5    Tan, C.C.6    Tan, L.7
  • 4
    • 84937927449 scopus 로고    scopus 로고
    • Cognitive reserve and Alzheimer’s disease
    • Xu W, Yu JT, Tan MS, Tan L (2014) Cognitive reserve and Alzheimer’s disease. Mol Neurobiol. doi:10.1007/s12035-014-8720-y
    • (2014) Mol Neurobiol
    • Xu, W.1    Yu, J.T.2    Tan, M.S.3    Tan, L.4
  • 5
    • 0026088977 scopus 로고
    • Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer’s disease
    • COI: 1:CAS:528:DyaK3MXhsFyhu7k%3D, PID: 1671712
    • Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, Giuffra L, Haynes A, Irving N, James L et al (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer’s disease. Nature 349(6311):704–706. doi:10.1038/349704a0
    • (1991) Nature , vol.349 , Issue.6311 , pp. 704-706
    • Goate, A.1    Chartier-Harlin, M.C.2    Mullan, M.3    Brown, J.4    Crawford, F.5    Fidani, L.6    Giuffra, L.7    Haynes, A.8    Irving, N.9    James, L.10
  • 8
    • 0027407565 scopus 로고
    • Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
    • COI: 1:CAS:528:DyaK3sXhs1Klsrs%3D, PID: 8446617
    • Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD (1993) Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A 90(5):1977–1981
    • (1993) Proc Natl Acad Sci U S A , vol.90 , Issue.5 , pp. 1977-1981
    • Strittmatter, W.J.1    Saunders, A.M.2    Schmechel, D.3    Pericak-Vance, M.4    Enghild, J.5    Salvesen, G.S.6    Roses, A.D.7
  • 9
    • 84904678185 scopus 로고    scopus 로고
    • Apolipoprotein e in Alzheimer’s disease: an update
    • COI: 1:CAS:528:DC%2BC2cXhsVKgt7fP, PID: 24821312
    • Yu JT, Tan L, Hardy J (2014) Apolipoprotein e in Alzheimer’s disease: an update. Annu Rev Neurosci 37:79–100. doi:10.1146/annurev-neuro-071013-014300
    • (2014) Annu Rev Neurosci , vol.37 , pp. 79-100
    • Yu, J.T.1    Tan, L.2    Hardy, J.3
  • 10
    • 0036592518 scopus 로고    scopus 로고
    • Non-familial Alzheimer’s disease is mainly due to genetic factors
    • PID: 12226536
    • Ashford JW, Mortimer JA (2002) Non-familial Alzheimer’s disease is mainly due to genetic factors. J Alzheimers Dis 4(3):169–177
    • (2002) J Alzheimers Dis , vol.4 , Issue.3 , pp. 169-177
    • Ashford, J.W.1    Mortimer, J.A.2
  • 11
    • 0032545939 scopus 로고    scopus 로고
    • Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer’s disease. Alzheimer’s Disease Centers Consortium on Apolipoprotein E and Alzheimer’s Disease
    • COI: 1:STN:280:DyaK1c7islCltA%3D%3D, PID: 9468467
    • Mayeux R, Saunders AM, Shea S, Mirra S, Evans D, Roses AD, Hyman BT, Crain B, Tang MX, Phelps CH (1998) Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer’s disease. Alzheimer’s Disease Centers Consortium on Apolipoprotein E and Alzheimer’s Disease. N Engl J Med 338(8):506–511. doi:10.1056/NEJM199802193380804
    • (1998) N Engl J Med , vol.338 , Issue.8 , pp. 506-511
    • Mayeux, R.1    Saunders, A.M.2    Shea, S.3    Mirra, S.4    Evans, D.5    Roses, A.D.6    Hyman, B.T.7    Crain, B.8    Tang, M.X.9    Phelps, C.H.10
  • 13
    • 78650513391 scopus 로고    scopus 로고
    • Genetic association of PICALM polymorphisms with Alzheimer’s disease in Han Chinese
    • COI: 1:CAS:528:DC%2BC3cXhs1Wgtb7M, PID: 20951388
    • Yu JT, Song JH, Ma T, Zhang W, Yu NN, Xuan SY, Tan L (2011) Genetic association of PICALM polymorphisms with Alzheimer’s disease in Han Chinese. J Neurol Sci 300(1–2):78–80. doi:10.1016/j.jns.2010.09.027
    • (2011) J Neurol Sci , vol.300 , Issue.1-2 , pp. 78-80
    • Yu, J.T.1    Song, J.H.2    Ma, T.3    Zhang, W.4    Yu, N.N.5    Xuan, S.Y.6    Tan, L.7
  • 15
    • 0042090267 scopus 로고    scopus 로고
    • Calcium-triggered membrane fusion proceeds independently of specific presynaptic proteins
    • COI: 1:CAS:528:DC%2BD3sXltVSmtrs%3D, PID: 12764142
    • Szule JA, Jarvis SE, Hibbert JE, Spafford JD, Braun JE, Zamponi GW, Wessel GM, Coorssen JR (2003) Calcium-triggered membrane fusion proceeds independently of specific presynaptic proteins. J Biol Chem 278(27):24251–24254. doi:10.1074/jbc.C300197200
    • (2003) J Biol Chem , vol.278 , Issue.27 , pp. 24251-24254
    • Szule, J.A.1    Jarvis, S.E.2    Hibbert, J.E.3    Spafford, J.D.4    Braun, J.E.5    Zamponi, G.W.6    Wessel, G.M.7    Coorssen, J.R.8
  • 20
    • 0035135419 scopus 로고    scopus 로고
    • Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes
    • COI: 1:CAS:528:DC%2BD3MXhtFGksL8%3D, PID: 11161218
    • Ford MG, Pearse BM, Higgins MK, Vallis Y, Owen DJ, Gibson A, Hopkins CR, Evans PR, McMahon HT (2001) Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes. Science 291(5506):1051–1055. doi:10.1126/science.291.5506.1051
    • (2001) Science , vol.291 , Issue.5506 , pp. 1051-1055
    • Ford, M.G.1    Pearse, B.M.2    Higgins, M.K.3    Vallis, Y.4    Owen, D.J.5    Gibson, A.6    Hopkins, C.R.7    Evans, P.R.8    McMahon, H.T.9
  • 21
    • 0142124232 scopus 로고    scopus 로고
    • Heterogeneity of endocytic proteins: distribution of clathrin adaptor proteins in neurons and glia
    • COI: 1:CAS:528:DC%2BD3sXmslehtrw%3D, PID: 12946697
    • Yao PJ, Zhang P, Mattson MP, Furukawa K (2003) Heterogeneity of endocytic proteins: distribution of clathrin adaptor proteins in neurons and glia. Neuroscience 121(1):25–37
    • (2003) Neuroscience , vol.121 , Issue.1 , pp. 25-37
    • Yao, P.J.1    Zhang, P.2    Mattson, M.P.3    Furukawa, K.4
  • 22
    • 0032807691 scopus 로고    scopus 로고
    • Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic
    • COI: 1:CAS:528:DyaK1MXlsVyqsr8%3D, PID: 10436022
    • Tebar F, Bohlander SK, Sorkin A (1999) Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic. Mol Biol Cell 10(8):2687–2702
    • (1999) Mol Biol Cell , vol.10 , Issue.8 , pp. 2687-2702
    • Tebar, F.1    Bohlander, S.K.2    Sorkin, A.3
  • 23
    • 55249094404 scopus 로고    scopus 로고
    • Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons
    • COI: 1:CAS:528:DC%2BD1cXht1GksLbO, PID: 18842885
    • Bushlin I, Petralia RS, Wu F, Harel A, Mughal MR, Mattson MP, Yao PJ (2008) Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons. J Neurosci 28(41):10257–10271
    • (2008) J Neurosci , vol.28 , Issue.41 , pp. 10257-10271
    • Bushlin, I.1    Petralia, R.S.2    Wu, F.3    Harel, A.4    Mughal, M.R.5    Mattson, M.P.6    Yao, P.J.7
  • 25
    • 84862270067 scopus 로고    scopus 로고
    • Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis
    • COI: 1:CAS:528:DC%2BC38Xos1Cktrk%3D, PID: 22539346
    • Xiao Q, Gil SC, Yan P, Wang Y, Han S, Gonzales E, Perez R, Cirrito JR, Lee JM (2012) Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis. J Biol Chem 287(25):21279–21289. doi:10.1074/jbc.M111.338376
    • (2012) J Biol Chem , vol.287 , Issue.25 , pp. 21279-21289
    • Xiao, Q.1    Gil, S.C.2    Yan, P.3    Wang, Y.4    Han, S.5    Gonzales, E.6    Perez, R.7    Cirrito, J.R.8    Lee, J.M.9
  • 26
    • 0029953937 scopus 로고    scopus 로고
    • The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family
    • COI: 1:CAS:528:DyaK28XjtVKlsb4%3D, PID: 8643484
    • Dreyling M, Martinez-Climent J, Zheng M, Mao J, Rowley J, Bohlander S (1996) The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family. Proc Natl Acad Sci 93(10):4804–4809
    • (1996) Proc Natl Acad Sci , vol.93 , Issue.10 , pp. 4804-4809
    • Dreyling, M.1    Martinez-Climent, J.2    Zheng, M.3    Mao, J.4    Rowley, J.5    Bohlander, S.6
  • 27
    • 36348940988 scopus 로고    scopus 로고
    • The CALM-AF10 fusion is a rare event in acute megakaryoblastic leukemia
    • COI: 1:CAS:528:DC%2BD2sXhtlaksr%2FO, PID: 17611559
    • Greiner O, Bornhauser BC, Delabesse E, Ballerini P, Landman-Parker J, Bourquin JP (2007) The CALM-AF10 fusion is a rare event in acute megakaryoblastic leukemia. Leukemia 21(12):2568–2569. doi:10.1038/sj.leu.2404835
    • (2007) Leukemia , vol.21 , Issue.12 , pp. 2568-2569
    • Greiner, O.1    Bornhauser, B.C.2    Delabesse, E.3    Ballerini, P.4    Landman-Parker, J.5    Bourquin, J.P.6
  • 28
    • 0038153918 scopus 로고    scopus 로고
    • Mutations in the clathrin-assembly gene PICALM are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice
    • COI: 1:CAS:528:DC%2BD3sXlsFGnt7k%3D, PID: 12832620
    • Klebig ML, Wall MD, Potter MD, Rowe EL, Carpenter DA, Rinchik EM (2003) Mutations in the clathrin-assembly gene PICALM are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice. Proc Natl Acad Sci U S A 100(14):8360–8365. doi:10.1073/pnas.1432634100
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.14 , pp. 8360-8365
    • Klebig, M.L.1    Wall, M.D.2    Potter, M.D.3    Rowe, E.L.4    Carpenter, D.A.5    Rinchik, E.M.6
  • 29
    • 84857375101 scopus 로고    scopus 로고
    • The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice
    • COI: 1:CAS:528:DC%2BC38XjsVaqtrs%3D, PID: 22363754
    • Suzuki M, Tanaka H, Tanimura A, Tanabe K, Oe N, Rai S, Kon S, Fukumoto M, Takei K, Abe T (2012) The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice. PLoS One 7(2):e31854
    • (2012) PLoS One , vol.7 , Issue.2 , pp. 31854
    • Suzuki, M.1    Tanaka, H.2    Tanimura, A.3    Tanabe, K.4    Oe, N.5    Rai, S.6    Kon, S.7    Fukumoto, M.8    Takei, K.9    Abe, T.10
  • 30
    • 0033538576 scopus 로고    scopus 로고
    • The structural era of endocytosis
    • COI: 1:CAS:528:DyaK1MXks1SjsL8%3D, PID: 10398591
    • Marsh M, McMahon HT (1999) The structural era of endocytosis. Science 285(5425):215–220
    • (1999) Science , vol.285 , Issue.5425 , pp. 215-220
    • Marsh, M.1    McMahon, H.T.2
  • 32
    • 54449093012 scopus 로고    scopus 로고
    • Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner implications for Alzheimer disease pathogenesis
    • COI: 1:CAS:528:DC%2BD1cXhtVyisLjE, PID: 18599481
    • Kyriazis GA, Wei Z, Vandermey M, Jo D-G, Xin O, Mattson MP, Chan SL (2008) Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner implications for Alzheimer disease pathogenesis. J Biol Chem 283(37):25492–25502
    • (2008) J Biol Chem , vol.283 , Issue.37 , pp. 25492-25502
    • Kyriazis, G.A.1    Wei, Z.2    Vandermey, M.3    Jo, D.-G.4    Xin, O.5    Mattson, M.P.6    Chan, S.L.7
  • 33
    • 69249135065 scopus 로고    scopus 로고
    • Tickets to ride: selecting cargo for clathrin-regulated internalization
    • COI: 1:CAS:528:DC%2BD1MXhtVaksrrE, PID: 19696796
    • Traub LM (2009) Tickets to ride: selecting cargo for clathrin-regulated internalization. Nat Rev Mol Cell Biol 10(9):583–596. doi:10.1038/nrm2751
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.9 , pp. 583-596
    • Traub, L.M.1
  • 34
    • 67349129779 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis and Alzheimer’s disease: an update
    • PID: 19491039
    • Wu F, Yao PJ (2009) Clathrin-mediated endocytosis and Alzheimer’s disease: an update. Ageing Res Rev 8(3):147–149. doi:10.1016/j.arr.2009.03.002
    • (2009) Ageing Res Rev , vol.8 , Issue.3 , pp. 147-149
    • Wu, F.1    Yao, P.J.2
  • 35
    • 78349278012 scopus 로고    scopus 로고
    • Clathrin‐mediated endocytosis at the synaptic terminal: bridging the gap between physiology and molecules
    • COI: 1:CAS:528:DC%2BC3cXhsFWiu73J, PID: 20633242
    • Royle SJ, Lagnado L (2010) Clathrin‐mediated endocytosis at the synaptic terminal: bridging the gap between physiology and molecules. Traffic 11(12):1489–1497
    • (2010) Traffic , vol.11 , Issue.12 , pp. 1489-1497
    • Royle, S.J.1    Lagnado, L.2
  • 36
    • 27744510147 scopus 로고    scopus 로고
    • Effect of clathrin assembly lymphoid myeloid leukemia protein depletion on clathrin coat formation
    • COI: 1:CAS:528:DC%2BD2MXht1OgtrrK, PID: 16262731
    • Meyerholz A, Hinrichsen L, Groos S, Esk PC, Brandes G, Ungewickell EJ (2005) Effect of clathrin assembly lymphoid myeloid leukemia protein depletion on clathrin coat formation. Traffic 6(12):1225–1234. doi:10.1111/j.1600-0854.2005.00355.x
    • (2005) Traffic , vol.6 , Issue.12 , pp. 1225-1234
    • Meyerholz, A.1    Hinrichsen, L.2    Groos, S.3    Esk, P.C.4    Brandes, G.5    Ungewickell, E.J.6
  • 37
    • 11444267601 scopus 로고    scopus 로고
    • Endosome function and dysfunction in Alzheimer’s disease and other neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BD2MXitVejuw%3D%3D, PID: 15639316
    • Nixon RA (2005) Endosome function and dysfunction in Alzheimer’s disease and other neurodegenerative diseases. Neurobiol Aging 26(3):373–382. doi:10.1016/j.neurobiolaging.2004.09.018
    • (2005) Neurobiol Aging , vol.26 , Issue.3 , pp. 373-382
    • Nixon, R.A.1
  • 43
    • 84855801442 scopus 로고    scopus 로고
    • Association of CLU and PICALM variants with Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC38XotVeqtg%3D%3D, PID: 20570404
    • Kamboh MI, Minster RL, Demirci FY, Ganguli M, Dekosky ST, Lopez OL, Barmada MM (2012) Association of CLU and PICALM variants with Alzheimer’s disease. Neurobiol Aging 33(3):518–521. doi:10.1016/j.neurobiolaging.2010.04.015
    • (2012) Neurobiol Aging , vol.33 , Issue.3 , pp. 518-521
    • Kamboh, M.I.1    Minster, R.L.2    Demirci, F.Y.3    Ganguli, M.4    Dekosky, S.T.5    Lopez, O.L.6    Barmada, M.M.7
  • 46
    • 84872345919 scopus 로고    scopus 로고
    • Lack of association between PICALM rs3851179 polymorphism and Alzheimer’s disease in Chinese population and APOEepsilon4-negative subgroup
    • COI: 1:CAS:528:DC%2BC2cXns1eqtbk%3D, PID: 23040034, e1319–1310
    • Liu G, Zhang L, Feng R, Liao M, Jiang Y, Chen Z, Zhao B, Li K (2013) Lack of association between PICALM rs3851179 polymorphism and Alzheimer’s disease in Chinese population and APOEepsilon4-negative subgroup. Neurobiol Aging 34(4):1310. doi:10.1016/j.neurobiolaging.2012.08.015, e1319–1310
    • (2013) Neurobiol Aging , vol.34 , Issue.4 , pp. 1310
    • Liu, G.1    Zhang, L.2    Feng, R.3    Liao, M.4    Jiang, Y.5    Chen, Z.6    Zhao, B.7    Li, K.8
  • 47
    • 85058205408 scopus 로고    scopus 로고
    • Genetic variation in PICALM and Alzheimer’s disease risk in Han Chinese
    • PID: 24095218, e931–933
    • Jiang T, Yu JT, Tan MS, Wang HF, Wang YL, Zhu XC, Zhang W, Tan L (2014) Genetic variation in PICALM and Alzheimer’s disease risk in Han Chinese. Neurobiol Aging 35(4):934. doi:10.1016/j.neurobiolaging.2013.09.014, e931–933
    • (2014) Neurobiol Aging , vol.35 , Issue.4 , pp. 934
    • Jiang, T.1    Yu, J.T.2    Tan, M.S.3    Wang, H.F.4    Wang, Y.L.5    Zhu, X.C.6    Zhang, W.7    Tan, L.8
  • 48
    • 81355148562 scopus 로고    scopus 로고
    • Polymorphisms of CR1, CLU and PICALM confer susceptibility of Alzheimer’s disease in a southern Chinese population
    • COI: 1:CAS:528:DC%2BC3sXisFygsbg%3D, PID: 22015308, e211–217
    • Chen LH, Kao PY, Fan YH, Ho DT, Chan CS, Yik PY, Ha JC, Chu LW, Song YQ (2012) Polymorphisms of CR1, CLU and PICALM confer susceptibility of Alzheimer’s disease in a southern Chinese population. Neurobiol Aging 33(1):210. doi:10.1016/j.neurobiolaging.2011.09.016, e211–217
    • (2012) Neurobiol Aging , vol.33 , Issue.1 , pp. 210
    • Chen, L.H.1    Kao, P.Y.2    Fan, Y.H.3    Ho, D.T.4    Chan, C.S.5    Yik, P.Y.6    Ha, J.C.7    Chu, L.W.8    Song, Y.Q.9
  • 52
    • 84877762031 scopus 로고    scopus 로고
    • PICALM gene rs3851179 polymorphism contributes to Alzheimer’s disease in an Asian population
    • COI: 1:CAS:528:DC%2BC3sXnsVWmt7g%3D
    • Liu G, Zhang S, Cai Z, Ma G, Zhang L, Jiang Y, Feng R, Liao M, Chen Z, Zhao B, Li K (2013) PICALM gene rs3851179 polymorphism contributes to Alzheimer’s disease in an Asian population. Neruomol Med 15(2):384–388. doi:10.1007/s12017-013-8225-2
    • (2013) Neruomol Med , vol.15 , Issue.2 , pp. 384-388
    • Liu, G.1    Zhang, S.2    Cai, Z.3    Ma, G.4    Zhang, L.5    Jiang, Y.6    Feng, R.7    Liao, M.8    Chen, Z.9    Zhao, B.10    Li, K.11
  • 53
    • 84869505704 scopus 로고    scopus 로고
    • Association study of susceptibility genes for late-onset Alzheimer’s disease in the Japanese population
    • COI: 1:CAS:528:DC%2BC3sXisVans7s%3D, PID: 22935915
    • Ohara T, Ninomiya T, Hirakawa Y, Ashikawa K, Monji A, Kiyohara Y, Kanba S, Kubo M (2012) Association study of susceptibility genes for late-onset Alzheimer’s disease in the Japanese population. Psychiatr Genet 22(6):290–293. doi:10.1097/YPG.0b013e3283586215
    • (2012) Psychiatr Genet , vol.22 , Issue.6 , pp. 290-293
    • Ohara, T.1    Ninomiya, T.2    Hirakawa, Y.3    Ashikawa, K.4    Monji, A.5    Kiyohara, Y.6    Kanba, S.7    Kubo, M.8
  • 55
    • 84894094478 scopus 로고    scopus 로고
    • Epistatic genetic effects among Alzheimer’s candidate genes AD
    • PID: 24260488
    • Hohman TJ, Koran ME, Thornton-Wells T, Alzheimer’s Neuroimaging I (2013) Epistatic genetic effects among Alzheimer’s candidate genes AD. PLoS One 8(11):e80839. doi:10.1371/journal.pone.0080839
    • (2013) PLoS One , vol.8 , Issue.11 , pp. 80839
    • Hohman, T.J.1    Koran, M.E.2    Thornton-Wells, T.3    Alzheimer’s Neuroimaging, I.4
  • 62
    • 80052632430 scopus 로고    scopus 로고
    • CR1 genotype is associated with entorhinal cortex volume in young healthy adults
    • PID: 21726919, e2107–2111
    • Bralten J, Franke B, Arias-Vasquez A, Heister A, Brunner HG, Fernandez G, Rijpkema M (2011) CR1 genotype is associated with entorhinal cortex volume in young healthy adults. Neurobiol Aging 32(11):2106. doi:10.1016/j.neurobiolaging.2011.05.017, e2107–2111
    • (2011) Neurobiol Aging , vol.32 , Issue.11 , pp. 2106
    • Bralten, J.1    Franke, B.2    Arias-Vasquez, A.3    Heister, A.4    Brunner, H.G.5    Fernandez, G.6    Rijpkema, M.7
  • 65
    • 84879880379 scopus 로고    scopus 로고
    • Evidence that PICALM affects age at onset of Alzheimer’s dementia in Down syndrome
    • PID: 23601808, e2441–2445
    • Jones EL, Mok K, Hanney M, Harold D, Sims R, Williams J, Ballard C (2013) Evidence that PICALM affects age at onset of Alzheimer’s dementia in Down syndrome. Neurobiol Aging 34(10):2441. doi:10.1016/j.neurobiolaging.2013.03.018, e2441–2445
    • (2013) Neurobiol Aging , vol.34 , Issue.10 , pp. 2441
    • Jones, E.L.1    Mok, K.2    Hanney, M.3    Harold, D.4    Sims, R.5    Williams, J.6    Ballard, C.7
  • 66
    • 84881545290 scopus 로고    scopus 로고
    • Alzheimer’s disease risk genes and the age-at-onset phenotype
    • PID: 23870418, e2691–2695
    • Thambisetty M, An Y, Tanaka T (2013) Alzheimer’s disease risk genes and the age-at-onset phenotype. Neurobiol Aging 34(11):2696. doi:10.1016/j.neurobiolaging.2013.05.028, e2691–2695
    • (2013) Neurobiol Aging , vol.34 , Issue.11 , pp. 2696
    • Thambisetty, M.1    An, Y.2    Tanaka, T.3
  • 68
    • 79952899509 scopus 로고    scopus 로고
    • Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old
    • PID: 20739100, e557–511
    • Mengel-From J, Christensen K, McGue M, Christiansen L (2011) Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old. Neurobiol Aging 32(3):554. doi:10.1016/j.neurobiolaging.2010.07.016, e557–511
    • (2011) Neurobiol Aging , vol.32 , Issue.3 , pp. 554
    • Mengel-From, J.1    Christensen, K.2    McGue, M.3    Christiansen, L.4
  • 69
    • 84857967988 scopus 로고    scopus 로고
    • Alzheimer’s disease: genetic polymorphisms and rate of decline
    • COI: 1:CAS:528:DC%2BC38Xpt1yrs7s%3D, PID: 22414550
    • Schmidt C, Wolff M, von Ahsen N, Zerr I (2012) Alzheimer’s disease: genetic polymorphisms and rate of decline. Dement Geriatr Cogn Disord 33(2–3):84–89. doi:10.1159/000336790
    • (2012) Dement Geriatr Cogn Disord , vol.33 , Issue.2-3 , pp. 84-89
    • Schmidt, C.1    Wolff, M.2    von Ahsen, N.3    Zerr, I.4
  • 71
    • 79952089521 scopus 로고    scopus 로고
    • Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3MXivFGntbk%3D, PID: 21390209
    • Hu X, Pickering E, Liu YC, Hall S, Fournier H, Katz E, Dechairo B, John S, Van Eerdewegh P, Soares H, Alzheimer’s Disease Neuroimaging I (2011) Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer’s disease. PLoS One 6(2):e16616. doi:10.1371/journal.pone.0016616
    • (2011) PLoS One , vol.6 , Issue.2 , pp. 16616
    • Hu, X.1    Pickering, E.2    Liu, Y.C.3    Hall, S.4    Fournier, H.5    Katz, E.6    Dechairo, B.7    John, S.8    Van Eerdewegh, P.9    Soares, H.10    Alzheimer’s Disease Neuroimaging, I.11
  • 77
    • 84867463470 scopus 로고    scopus 로고
    • Identification and confirmation of an exonic splicing enhancer variation in exon 5 of the Alzheimer disease associated PICALM gene
    • COI: 1:CAS:528:DC%2BC38XhvVKgt7jO, PID: 22943764
    • Schnetz-Boutaud NC, Hoffman J, Coe JE, Murdock DG, Pericak-Vance MA, Haines JL (2012) Identification and confirmation of an exonic splicing enhancer variation in exon 5 of the Alzheimer disease associated PICALM gene. Ann Hum Genet 76(6):448–453. doi:10.1111/j.1469-1809.2012.00727.x
    • (2012) Ann Hum Genet , vol.76 , Issue.6 , pp. 448-453
    • Schnetz-Boutaud, N.C.1    Hoffman, J.2    Coe, J.E.3    Murdock, D.G.4    Pericak-Vance, M.A.5    Haines, J.L.6
  • 78
    • 79953285123 scopus 로고    scopus 로고
    • CLU, CR1 and PICALM genes associate with Alzheimer’s-related senile plaques
    • COI: 1:CAS:528:DC%2BC3MXkvFKjur0%3D, PID: 21466683
    • Kok EH, Luoto T, Haikonen S, Goebeler S, Haapasalo H, Karhunen PJ (2011) CLU, CR1 and PICALM genes associate with Alzheimer’s-related senile plaques. Alzheimers Res Ther 3(2):12. doi:10.1186/alzrt71
    • (2011) Alzheimers Res Ther , vol.3 , Issue.2 , pp. 12
    • Kok, E.H.1    Luoto, T.2    Haikonen, S.3    Goebeler, S.4    Haapasalo, H.5    Karhunen, P.J.6
  • 79
    • 0027936838 scopus 로고
    • Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease
    • COI: 1:CAS:528:DyaK2cXmsFamsbg%3D, PID: 8083686
    • Roses AD (1994) Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease. J Neuropathol Exp Neurol 53(5):429–437
    • (1994) J Neuropathol Exp Neurol , vol.53 , Issue.5 , pp. 429-437
    • Roses, A.D.1
  • 80
    • 84884135317 scopus 로고    scopus 로고
    • Memory decline shows stronger associations with estimated spatial patterns of amyloid deposition progression than total amyloid burden
    • COI: 1:CAS:528:DC%2BC3sXhtFSmurfL, PID: 23859610
    • Yotter RA, Doshi J, Clark V, Sojkova J, Zhou Y, Wong DF, Ferrucci L, Resnick SM, Davatzikos C (2013) Memory decline shows stronger associations with estimated spatial patterns of amyloid deposition progression than total amyloid burden. Neurobiol Aging 34(12):2835–2842. doi:10.1016/j.neurobiolaging.2013.05.030
    • (2013) Neurobiol Aging , vol.34 , Issue.12 , pp. 2835-2842
    • Yotter, R.A.1    Doshi, J.2    Clark, V.3    Sojkova, J.4    Zhou, Y.5    Wong, D.F.6    Ferrucci, L.7    Resnick, S.M.8    Davatzikos, C.9
  • 81
    • 47149112621 scopus 로고    scopus 로고
    • Long-term effects of Abeta42 immunisation in Alzheimer’s disease: follow-up of a randomised, placebo-controlled phase I trial
    • COI: 1:CAS:528:DC%2BD1cXoslWkt74%3D, PID: 18640458
    • Holmes C, Boche D, Wilkinson D, Yadegarfar G, Hopkins V, Bayer A, Jones RW, Bullock R, Love S, Neal JW, Zotova E, Nicoll JA (2008) Long-term effects of Abeta42 immunisation in Alzheimer’s disease: follow-up of a randomised, placebo-controlled phase I trial. Lancet 372(9634):216–223. doi:10.1016/S0140-6736(08)61075-2
    • (2008) Lancet , vol.372 , Issue.9634 , pp. 216-223
    • Holmes, C.1    Boche, D.2    Wilkinson, D.3    Yadegarfar, G.4    Hopkins, V.5    Bayer, A.6    Jones, R.W.7    Bullock, R.8    Love, S.9    Neal, J.W.10    Zotova, E.11    Nicoll, J.A.12
  • 82
    • 77950617631 scopus 로고    scopus 로고
    • A mouse model of amyloid β oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo
    • COI: 1:CAS:528:DC%2BC3cXlvVKntr0%3D, PID: 20371804
    • Tomiyama T, Matsuyama S, Iso H, Umeda T, Takuma H, Ohnishi K, Ishibashi K, Teraoka R, Sakama N, Yamashita T (2010) A mouse model of amyloid β oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo. J Neurosci 30(14):4845–4856
    • (2010) J Neurosci , vol.30 , Issue.14 , pp. 4845-4856
    • Tomiyama, T.1    Matsuyama, S.2    Iso, H.3    Umeda, T.4    Takuma, H.5    Ohnishi, K.6    Ishibashi, K.7    Teraoka, R.8    Sakama, N.9    Yamashita, T.10
  • 83
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer’s disease: genes, proteins, and therapy
    • COI: 1:CAS:528:DC%2BD3MXislCrsLc%3D, PID: 11274343
    • Selkoe DJ (2001) Alzheimer’s disease: genes, proteins, and therapy. Physiol Rev 81(2):741–766
    • (2001) Physiol Rev , vol.81 , Issue.2 , pp. 741-766
    • Selkoe, D.J.1
  • 84
    • 33644849690 scopus 로고    scopus 로고
    • Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments
    • COI: 1:CAS:528:DC%2BD28Xht1Kruw%3D%3D, PID: 16432149
    • Vetrivel KS, Thinakaran G (2006) Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments. Neurology 66(2 Suppl 1):S69–S73. doi:10.1212/01.wnl.0000192107.17175.39
    • (2006) Neurology , vol.66 , pp. 69-73
    • Vetrivel, K.S.1    Thinakaran, G.2
  • 85
    • 41549155927 scopus 로고    scopus 로고
    • Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo
    • COI: 1:CAS:528:DC%2BD1cXltVOisrc%3D, PID: 18400162
    • Cirrito JR, Kang JE, Lee J, Stewart FR, Verges DK, Silverio LM, Bu G, Mennerick S, Holtzman DM (2008) Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo. Neuron 58(1):42–51. doi:10.1016/j.neuron.2008.02.003
    • (2008) Neuron , vol.58 , Issue.1 , pp. 42-51
    • Cirrito, J.R.1    Kang, J.E.2    Lee, J.3    Stewart, F.R.4    Verges, D.K.5    Silverio, L.M.6    Bu, G.7    Mennerick, S.8    Holtzman, D.M.9
  • 86
    • 66449086924 scopus 로고    scopus 로고
    • Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration
    • COI: 1:CAS:528:DC%2BD1MXltVCls7w%3D, PID: 19240038
    • Rudinskiy N, Grishchuk Y, Vaslin A, Puyal J, Delacourte A, Hirling H, Clarke PG, Luthi-Carter R (2009) Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration. J Biol Chem 284(18):12447–12458. doi:10.1074/jbc.M804740200
    • (2009) J Biol Chem , vol.284 , Issue.18 , pp. 12447-12458
    • Rudinskiy, N.1    Grishchuk, Y.2    Vaslin, A.3    Puyal, J.4    Delacourte, A.5    Hirling, H.6    Clarke, P.G.7    Luthi-Carter, R.8
  • 87
    • 0035980917 scopus 로고    scopus 로고
    • Cleavage of purified neuronal clathrin assembly protein (CALM) by caspase 3 and calpain
    • COI: 1:CAS:528:DC%2BD38XnsFegsg%3D%3D, PID: 11795487
    • Kim JA, Kim HL (2001) Cleavage of purified neuronal clathrin assembly protein (CALM) by caspase 3 and calpain. Exp Mol Med 33(4):245–250. doi:10.1038/emm.2001.40
    • (2001) Exp Mol Med , vol.33 , Issue.4 , pp. 245-250
    • Kim, J.A.1    Kim, H.L.2
  • 89
    • 84872085620 scopus 로고    scopus 로고
    • A yeast model for amyloid-beta aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity
    • D’Angelo F, Vignaud H, Di Martino J, Salin B, Devin A, Cullin C, Marchal C (2013) A yeast model for amyloid-beta aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity. Dis Models Mech 6(1):206–216. doi:10.1242/dmm.010108
    • (2013) Dis Models Mech , vol.6 , Issue.1 , pp. 206-216
    • D’Angelo, F.1    Vignaud, H.2    Di Martino, J.3    Salin, B.4    Devin, A.5    Cullin, C.6    Marchal, C.7
  • 91
    • 84893714992 scopus 로고    scopus 로고
    • Autophagy in aging and neurodegenerative diseases: implications for pathogenesis and therapy
    • PID: 24360503
    • Tan CC, Yu JT, Tan MS, Jiang T, Zhu XC, Tan L (2014) Autophagy in aging and neurodegenerative diseases: implications for pathogenesis and therapy. Neurobiol Aging 35(5):941–957. doi:10.1016/j.neurobiolaging.2013.11.019
    • (2014) Neurobiol Aging , vol.35 , Issue.5 , pp. 941-957
    • Tan, C.C.1    Yu, J.T.2    Tan, M.S.3    Jiang, T.4    Zhu, X.C.5    Tan, L.6
  • 92
    • 79251556232 scopus 로고    scopus 로고
    • Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-beta peptide degradation
    • COI: 1:CAS:528:DC%2BC3MXls1GmtA%3D%3D
    • Vingtdeux V, Chandakkar P, Zhao H, d’Abramo C, Davies P, Marambaud P (2011) Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-beta peptide degradation. FASEB J Off Publ Fed Am Soc Exp Biol 25(1):219–231. doi:10.1096/fj.10-167361
    • (2011) FASEB J Off Publ Fed Am Soc Exp Biol , vol.25 , Issue.1 , pp. 219-231
    • Vingtdeux, V.1    Chandakkar, P.2    Zhao, H.3    d’Abramo, C.4    Davies, P.5    Marambaud, P.6
  • 93
    • 79957917512 scopus 로고    scopus 로고
    • A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway
    • COI: 1:CAS:528:DC%2BC3MXnsFyqt70%3D
    • Tian Y, Bustos V, Flajolet M, Greengard P (2011) A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway. FASEB J Off Publ Fed Am Soc Exp Biol 25(6):1934–1942. doi:10.1096/fj.10-175158
    • (2011) FASEB J Off Publ Fed Am Soc Exp Biol , vol.25 , Issue.6 , pp. 1934-1942
    • Tian, Y.1    Bustos, V.2    Flajolet, M.3    Greengard, P.4
  • 94
    • 84885736277 scopus 로고    scopus 로고
    • Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer’s APP-CTF for terminal degradation via autophagy
    • COI: 1:CAS:528:DC%2BC3sXhslejsbbM, PID: 24067654
    • Tian Y, Chang JC, Fan EY, Flajolet M, Greengard P (2013) Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer’s APP-CTF for terminal degradation via autophagy. Proc Natl Acad Sci U S A 110(42):17071–17076. doi:10.1073/pnas.1315110110
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.42 , pp. 17071-17076
    • Tian, Y.1    Chang, J.C.2    Fan, E.Y.3    Flajolet, M.4    Greengard, P.5
  • 95
    • 84898614697 scopus 로고    scopus 로고
    • The convergence of endosomal and autophagosomal pathways: implications for APP-CTF degradation
    • COI: 1:CAS:528:DC%2BC2cXitVOhtbvP, PID: 24447917
    • Tian Y, Chang JC, Greengard P, Flajolet M (2014) The convergence of endosomal and autophagosomal pathways: implications for APP-CTF degradation. Autophagy 10(4):694–696
    • (2014) Autophagy , vol.10 , Issue.4 , pp. 694-696
    • Tian, Y.1    Chang, J.C.2    Greengard, P.3    Flajolet, M.4
  • 96
    • 79951499355 scopus 로고    scopus 로고
    • The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels
    • COI: 1:CAS:528:DC%2BC3MXis1ens7Y%3D, PID: 21300948
    • Schjeide BM, Schnack C, Lambert JC, Lill CM, Kirchheiner J, Tumani H, Otto M, Tanzi RE, Lehrach H, Amouyel P, von Arnim CA, Bertram L (2011) The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels. Arch Gen Psychiatry 68(2):207–213. doi:10.1001/archgenpsychiatry.2010.196
    • (2011) Arch Gen Psychiatry , vol.68 , Issue.2 , pp. 207-213
    • Schjeide, B.M.1    Schnack, C.2    Lambert, J.C.3    Lill, C.M.4    Kirchheiner, J.5    Tumani, H.6    Otto, M.7    Tanzi, R.E.8    Lehrach, H.9    Amouyel, P.10    von Arnim, C.A.11    Bertram, L.12
  • 98
    • 73449083442 scopus 로고    scopus 로고
    • Use of cerebrospinal fluid biomarkers for diagnosis of incipient Alzheimer disease in patients with mild cognitive impairment
    • COI: 1:CAS:528:DC%2BC3cXmtVKqsQ%3D%3D, PID: 19926774
    • Dean RA, Shaw LM (2010) Use of cerebrospinal fluid biomarkers for diagnosis of incipient Alzheimer disease in patients with mild cognitive impairment. Clin Chem 56(1):7–9. doi:10.1373/clinchem.2009.134692
    • (2010) Clin Chem , vol.56 , Issue.1 , pp. 7-9
    • Dean, R.A.1    Shaw, L.M.2
  • 99
    • 84861182718 scopus 로고    scopus 로고
    • Using CSF biomarkers to replicate genetic associations in Alzheimer’s disease
    • PID: 21459483, e1489–1415
    • Schott JM, Investigators A (2012) Using CSF biomarkers to replicate genetic associations in Alzheimer’s disease. Neurobiol Aging 33(7):1486. doi:10.1016/j.neurobiolaging.2011.02.008, e1489–1415
    • (2012) Neurobiol Aging , vol.33 , Issue.7 , pp. 1486
    • Schott, J.M.1    Investigators, A.2
  • 100
    • 3042622290 scopus 로고    scopus 로고
    • Neural transmitter release: from quantal secretion to exocytosis and beyond
    • COI: 1:CAS:528:DC%2BD2cXitlGktrY%3D, PID: 15034246
    • Katz B (2003) Neural transmitter release: from quantal secretion to exocytosis and beyond. J Neurocytol 32(5–8):437–446. doi:10.1023/B:NEUR.0000020603.84188.03
    • (2003) J Neurocytol , vol.32 , Issue.5-8 , pp. 437-446
    • Katz, B.1
  • 101
    • 33747622293 scopus 로고    scopus 로고
    • SNAREs—engines for membrane fusion
    • COI: 1:CAS:528:DC%2BD28Xot12ju7g%3D, PID: 16912714
    • Jahn R, Scheller RH (2006) SNAREs—engines for membrane fusion. Nat Rev Mol Cell Biol 7(9):631–643. doi:10.1038/nrm2002
    • (2006) Nat Rev Mol Cell Biol , vol.7 , Issue.9 , pp. 631-643
    • Jahn, R.1    Scheller, R.H.2
  • 102
    • 33746899756 scopus 로고    scopus 로고
    • The synaptic vesicle: cycle of exocytosis and endocytosis
    • COI: 1:CAS:528:DC%2BD28Xmt1OkurY%3D, PID: 16707259
    • Schweizer FE, Ryan TA (2006) The synaptic vesicle: cycle of exocytosis and endocytosis. Curr Opin Neurobiol 16(3):298–304. doi:10.1016/j.conb.2006.05.006
    • (2006) Curr Opin Neurobiol , vol.16 , Issue.3 , pp. 298-304
    • Schweizer, F.E.1    Ryan, T.A.2
  • 103
    • 38849199843 scopus 로고    scopus 로고
    • Evidence for CALM in directing VAMP2 trafficking
    • COI: 1:CAS:528:DC%2BD1cXisVakurg%3D, PID: 18182011
    • Harel A, Wu F, Mattson MP, Morris CM, Yao PJ (2008) Evidence for CALM in directing VAMP2 trafficking. Traffic 9(3):417–429. doi:10.1111/j.1600-0854.2007.00694.x
    • (2008) Traffic , vol.9 , Issue.3 , pp. 417-429
    • Harel, A.1    Wu, F.2    Mattson, M.P.3    Morris, C.M.4    Yao, P.J.5
  • 104
    • 81855227615 scopus 로고    scopus 로고
    • The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM
    • COI: 1:CAS:528:DC%2BC3MXhsFeisrjL, PID: 22118466
    • Miller SE, Sahlender DA, Graham SC, Honing S, Robinson MS, Peden AA, Owen DJ (2011) The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell 147(5):1118–1131. doi:10.1016/j.cell.2011.10.038
    • (2011) Cell , vol.147 , Issue.5 , pp. 1118-1131
    • Miller, S.E.1    Sahlender, D.A.2    Graham, S.C.3    Honing, S.4    Robinson, M.S.5    Peden, A.A.6    Owen, D.J.7
  • 105
    • 84865054611 scopus 로고    scopus 로고
    • Amyloid-beta acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2
    • COI: 1:CAS:528:DC%2BC38Xht1ejtLzI, PID: 22905234
    • Russell CL, Semerdjieva S, Empson RM, Austen BM, Beesley PW, Alifragis P (2012) Amyloid-beta acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2. PLoS One 7(8):e43201. doi:10.1371/journal.pone.0043201
    • (2012) PLoS One , vol.7 , Issue.8 , pp. 43201
    • Russell, C.L.1    Semerdjieva, S.2    Empson, R.M.3    Austen, B.M.4    Beesley, P.W.5    Alifragis, P.6
  • 106
    • 79952697049 scopus 로고    scopus 로고
    • CALM, a clathrin assembly protein, influences cell surface GluR2 abundance
    • COI: 1:CAS:528:DC%2BC3MXisVWmsr0%3D
    • Harel A, Mattson MP, Yao PJ (2011) CALM, a clathrin assembly protein, influences cell surface GluR2 abundance. Neruomol Med 13(1):88–90. doi:10.1007/s12017-010-8142-6
    • (2011) Neruomol Med , vol.13 , Issue.1 , pp. 88-90
    • Harel, A.1    Mattson, M.P.2    Yao, P.J.3
  • 107
    • 54549119477 scopus 로고    scopus 로고
    • Activity-dependent coordination of presynaptic release probability and postsynaptic GluR2 abundance at single synapses
    • COI: 1:CAS:528:DC%2BD1cXht1Sgt7zP, PID: 18794522
    • Tokuoka H, Goda Y (2008) Activity-dependent coordination of presynaptic release probability and postsynaptic GluR2 abundance at single synapses. Proc Natl Acad Sci U S A 105(38):14656–14661. doi:10.1073/pnas.0805705105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.38 , pp. 14656-14661
    • Tokuoka, H.1    Goda, Y.2
  • 108
    • 34249672242 scopus 로고    scopus 로고
    • Abeta oligomers induce neuronal oxidative stress through an N-methyl-d-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
    • PID: 17308309
    • De Felice FG, Velasco PT, Lambert MP, Viola K, Fernandez SJ, Ferreira ST, Klein WL (2007) Abeta oligomers induce neuronal oxidative stress through an N-methyl-d-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine. J Biol Chem 282(15):11590–11601. doi:10.1074/jbc.M607483200
    • (2007) J Biol Chem , vol.282 , Issue.15 , pp. 11590-11601
    • De Felice, F.G.1    Velasco, P.T.2    Lambert, M.P.3    Viola, K.4    Fernandez, S.J.5    Ferreira, S.T.6    Klein, W.L.7
  • 109
    • 84859510372 scopus 로고    scopus 로고
    • Elevated 4-hydroxyhexenal in Alzheimer’s disease (AD) progression
    • COI: 1:CAS:528:DC%2BC38XlslShsL0%3D, PID: 20965613
    • Bradley MA, Xiong-Fister S, Markesbery WR, Lovell MA (2012) Elevated 4-hydroxyhexenal in Alzheimer’s disease (AD) progression. Neurobiol Aging 33(6):1034–1044. doi:10.1016/j.neurobiolaging.2010.08.016
    • (2012) Neurobiol Aging , vol.33 , Issue.6 , pp. 1034-1044
    • Bradley, M.A.1    Xiong-Fister, S.2    Markesbery, W.R.3    Lovell, M.A.4
  • 112
    • 84861906883 scopus 로고    scopus 로고
    • Genetic variants influencing human aging from late-onset Alzheimer’s disease (LOAD) genome-wide association studies (GWAS)
    • PID: 22445811, e1845–1818
    • Shi H, Belbin O, Medway C, Brown K, Kalsheker N, Carrasquillo M, Proitsi P, Powell J, Lovestone S, Goate A, Younkin S, Passmore P, Genetic and Environmental Risk for Alzheimer’s Disease Consortium, Morgan K, Alzheimer’s Research UK Consortium (2012) Genetic variants influencing human aging from late-onset Alzheimer’s disease (LOAD) genome-wide association studies (GWAS). Neurobiol Aging 33(8):1849. doi:10.1016/j.neurobiolaging.2012.02.014, e1845–1818
    • (2012) Neurobiol Aging , vol.33 , Issue.8 , pp. 1849
    • Shi, H.1    Belbin, O.2    Medway, C.3    Brown, K.4    Kalsheker, N.5    Carrasquillo, M.6    Proitsi, P.7    Powell, J.8    Lovestone, S.9    Goate, A.10    Younkin, S.11    Passmore, P.12    Morgan, K.13
  • 113
    • 84895515551 scopus 로고    scopus 로고
    • Effects of statins on incident dementia in patients with type 2 DM: a population-based retrospective cohort study in Taiwan
    • PID: 24520388
    • Chen JM, Chang CW, Chang TH, Hsu CC, Horng JT, Sheu WH (2014) Effects of statins on incident dementia in patients with type 2 DM: a population-based retrospective cohort study in Taiwan. PLoS One 9(2):e88434. doi:10.1371/journal.pone.0088434
    • (2014) PLoS One , vol.9 , Issue.2 , pp. 88434
    • Chen, J.M.1    Chang, C.W.2    Chang, T.H.3    Hsu, C.C.4    Horng, J.T.5    Sheu, W.H.6
  • 114
    • 84893971757 scopus 로고    scopus 로고
    • Simvastatin treatment preserves synaptic plasticity in AbetaPPswe/PS1dE9 mice
    • COI: 1:CAS:528:DC%2BC2cXhtFKlsrg%3D, PID: 24164738
    • Metais C, Brennan K, Mably AJ, Scott M, Walsh DM, Herron CE (2014) Simvastatin treatment preserves synaptic plasticity in AbetaPPswe/PS1dE9 mice. J Alzheimer’s Dis JAD 39(2):315–329. doi:10.3233/JAD-130257
    • (2014) J Alzheimer’s Dis JAD , vol.39 , Issue.2 , pp. 315-329
    • Metais, C.1    Brennan, K.2    Mably, A.J.3    Scott, M.4    Walsh, D.M.5    Herron, C.E.6
  • 115
    • 84875805775 scopus 로고    scopus 로고
    • Statins in the prevention of dementia and Alzheimer’s disease: a meta-analysis of observational studies and an assessment of confounding
    • COI: 1:CAS:528:DC%2BC3sXltlKksLY%3D, PID: 23225700
    • Wong WB, Lin VW, Boudreau D, Devine EB (2013) Statins in the prevention of dementia and Alzheimer’s disease: a meta-analysis of observational studies and an assessment of confounding. Pharmacoepidemiol Drug Saf 22(4):345–358. doi:10.1002/pds.3381
    • (2013) Pharmacoepidemiol Drug Saf , vol.22 , Issue.4 , pp. 345-358
    • Wong, W.B.1    Lin, V.W.2    Boudreau, D.3    Devine, E.B.4
  • 116
    • 84885189956 scopus 로고    scopus 로고
    • Selective benefits of simvastatin in bitransgenic APPSwe, Ind/TGF-beta1 mice
    • COI: 1:CAS:528:DC%2BC3sXht1ylsb7O, PID: 23954171
    • Papadopoulos P, Tong XK, Hamel E (2014) Selective benefits of simvastatin in bitransgenic APPSwe, Ind/TGF-beta1 mice. Neurobiol Aging 35(1):203–212. doi:10.1016/j.neurobiolaging.2013.07.010
    • (2014) Neurobiol Aging , vol.35 , Issue.1 , pp. 203-212
    • Papadopoulos, P.1    Tong, X.K.2    Hamel, E.3
  • 117
    • 84855525518 scopus 로고    scopus 로고
    • Genetics of late-onset Alzheimer’s disease: update from the alzgene database and analysis of shared pathways
    • PID: 22191060
    • Olgiati P, Politis AM, Papadimitriou GN, De Ronchi D, Serretti A (2011) Genetics of late-onset Alzheimer’s disease: update from the alzgene database and analysis of shared pathways. Int J Alzheimers Dis 2011:832379. doi:10.4061/2011/832379
    • (2011) Int J Alzheimers Dis , vol.2011 , pp. 832379
    • Olgiati, P.1    Politis, A.M.2    Papadimitriou, G.N.3    De Ronchi, D.4    Serretti, A.5
  • 118
    • 79959396151 scopus 로고    scopus 로고
    • The three new pathways leading to Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3MXot1Cru70%3D, PID: 21486313
    • Morgan K (2011) The three new pathways leading to Alzheimer’s disease. Neuropathol Appl Neurobiol 37(4):353–357. doi:10.1111/j.1365-2990.2011.01181.x
    • (2011) Neuropathol Appl Neurobiol , vol.37 , Issue.4 , pp. 353-357
    • Morgan, K.1
  • 119
    • 79960345867 scopus 로고    scopus 로고
    • Genetics: finding risk factors
    • COI: 1:CAS:528:DC%2BC3MXovFegsrk%3D, PID: 21760580
    • Eisenstein M (2011) Genetics: finding risk factors. Nature 475(7355):S20–S22. doi:10.1038/475S20a
    • (2011) Nature , vol.475 , Issue.7355 , pp. 20-22
    • Eisenstein, M.1
  • 121
    • 84875365096 scopus 로고    scopus 로고
    • Intracerebral propagation of Alzheimer’s disease: strengthening evidence of a herpes simplex virus etiology
    • Ball MJ, Lukiw WJ, Kammerman EM, Hill JM (2013) Intracerebral propagation of Alzheimer’s disease: strengthening evidence of a herpes simplex virus etiology. Alzheimer’s Dement J Alzheimer’s Assoc 9(2):169–175. doi:10.1016/j.jalz.2012.07.005
    • (2013) Alzheimer’s Dement J Alzheimer’s Assoc , vol.9 , Issue.2 , pp. 169-175
    • Ball, M.J.1    Lukiw, W.J.2    Kammerman, E.M.3    Hill, J.M.4
  • 122
    • 84875806478 scopus 로고    scopus 로고
    • Intravenous immunoglobulin reduces beta amyloid and abnormal tau formation caused by herpes simplex virus type 1
    • COI: 1:CAS:528:DC%2BC3sXhvFWquro%3D, PID: 23385080
    • Wozniak MA, Itzhaki RF (2013) Intravenous immunoglobulin reduces beta amyloid and abnormal tau formation caused by herpes simplex virus type 1. J Neuroimmunol 257(1–2):7–12. doi:10.1016/j.jneuroim.2013.01.005
    • (2013) J Neuroimmunol , vol.257 , Issue.1-2 , pp. 7-12
    • Wozniak, M.A.1    Itzhaki, R.F.2
  • 123
    • 84894205406 scopus 로고    scopus 로고
    • How plausible is a link between HSV-1 infection and Alzheimer’s disease?
    • COI: 1:CAS:528:DC%2BC2cXitFylu7Y%3D, PID: 24502805
    • Agostini S, Clerici M, Mancuso R (2014) How plausible is a link between HSV-1 infection and Alzheimer’s disease? Expert Rev Anti-Infect Ther 12(3):275–278. doi:10.1586/14787210.2014.887442
    • (2014) Expert Rev Anti-Infect Ther , vol.12 , Issue.3 , pp. 275-278
    • Agostini, S.1    Clerici, M.2    Mancuso, R.3
  • 124
    • 84890539671 scopus 로고    scopus 로고
    • Titers of herpes simplex virus type 1 antibodies positively correlate with grey matter volumes in Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3sXhvV2iu77L
    • Mancuso R, Baglio F, Cabinio M, Calabrese E, Hernis A, Nemni R, Clerici M (2014) Titers of herpes simplex virus type 1 antibodies positively correlate with grey matter volumes in Alzheimer’s disease. J Alzheimer’s Dis 38(4):741–745. doi:10.3233/JAD-130977
    • (2014) J Alzheimer’s Dis , vol.38 , Issue.4 , pp. 741-745
    • Mancuso, R.1    Baglio, F.2    Cabinio, M.3    Calabrese, E.4    Hernis, A.5    Nemni, R.6    Clerici, M.7
  • 126
    • 84455162524 scopus 로고    scopus 로고
    • Gene signature in Alzheimer’s disease and environmental factors: the virus chronicle
    • COI: 1:CAS:528:DC%2BC3MXhs1Sls7nK
    • Licastro F, Carbone I, Ianni M, Porcellini E (2011) Gene signature in Alzheimer’s disease and environmental factors: the virus chronicle. J Alzheimer’s Dis 27(4):809–817. doi:10.3233/JAD-2011-110755
    • (2011) J Alzheimer’s Dis , vol.27 , Issue.4 , pp. 809-817
    • Licastro, F.1    Carbone, I.2    Ianni, M.3    Porcellini, E.4
  • 127
    • 84855549785 scopus 로고    scopus 로고
    • Alzheimer’s disease: APP, gamma secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and their relationships with Herpes simplex, C. pneumoniae, other suspect pathogens, and the immune system
    • PID: 22254144
    • Carter C (2011) Alzheimer’s disease: APP, gamma secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and their relationships with Herpes simplex, C. pneumoniae, other suspect pathogens, and the immune system. Int J Alzheimers Dis 2011:501862. doi:10.4061/2011/501862
    • (2011) Int J Alzheimers Dis , vol.2011 , pp. 501862
    • Carter, C.1
  • 128
    • 77956189276 scopus 로고    scopus 로고
    • APP, APOE, complement receptor 1, clusterin and PICALM and their involvement in the herpes simplex life cycle
    • COI: 1:CAS:528:DC%2BC3cXhtFamsbjI, PID: 20674675
    • Carter CJ (2010) APP, APOE, complement receptor 1, clusterin and PICALM and their involvement in the herpes simplex life cycle. Neurosci Lett 483(2):96–100. doi:10.1016/j.neulet.2010.07.066
    • (2010) Neurosci Lett , vol.483 , Issue.2 , pp. 96-100
    • Carter, C.J.1
  • 129
    • 79952176117 scopus 로고    scopus 로고
    • Alzheimer’s disease: a pathogenetic autoimmune disorder caused by herpes simplex in a gene-dependent manner
    • COI: 1:STN:280:DC%2BC3M7hsFWitw%3D%3D, PID: 21234306
    • Carter CJ (2010) Alzheimer’s disease: a pathogenetic autoimmune disorder caused by herpes simplex in a gene-dependent manner. Int J Alzheimers Dis 2010:140539. doi:10.4061/2010/140539
    • (2010) Int J Alzheimers Dis , vol.2010 , pp. 140539
    • Carter, C.J.1
  • 131
    • 84893721804 scopus 로고    scopus 로고
    • Reducing iron in the brain: a novel pharmacologic mechanism of huperzine A in the treatment of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3sXitVWjtrzN, PID: 24332448
    • Huang XT, Qian ZM, He X, Gong Q, Wu KC, Jiang LR, Lu LN, Zhu ZJ, Zhang HY, Yung WH, Ke Y (2014) Reducing iron in the brain: a novel pharmacologic mechanism of huperzine A in the treatment of Alzheimer’s disease. Neurobiol Aging 35(5):1045–1054. doi:10.1016/j.neurobiolaging.2013.11.004
    • (2014) Neurobiol Aging , vol.35 , Issue.5 , pp. 1045-1054
    • Huang, X.T.1    Qian, Z.M.2    He, X.3    Gong, Q.4    Wu, K.C.5    Jiang, L.R.6    Lu, L.N.7    Zhu, Z.J.8    Zhang, H.Y.9    Yung, W.H.10    Ke, Y.11
  • 132
    • 84870481457 scopus 로고    scopus 로고
    • Mitochondrial ferritin attenuates beta-amyloid-induced neurotoxicity: reduction in oxidative damage through the Erk/P38 mitogen-activated protein kinase pathways
    • COI: 1:CAS:528:DC%2BC38XhslGksLzL, PID: 22746342
    • Wu WS, Zhao YS, Shi ZH, Chang SY, Nie GJ, Duan XL, Zhao SM, Wu Q, Yang ZL, Zhao BL, Chang YZ (2013) Mitochondrial ferritin attenuates beta-amyloid-induced neurotoxicity: reduction in oxidative damage through the Erk/P38 mitogen-activated protein kinase pathways. Antioxid Redox Signal 18(2):158–169. doi:10.1089/ars.2011.4285
    • (2013) Antioxid Redox Signal , vol.18 , Issue.2 , pp. 158-169
    • Wu, W.S.1    Zhao, Y.S.2    Shi, Z.H.3    Chang, S.Y.4    Nie, G.J.5    Duan, X.L.6    Zhao, S.M.7    Wu, Q.8    Yang, Z.L.9    Zhao, B.L.10    Chang, Y.Z.11
  • 133
  • 135
    • 84889640924 scopus 로고    scopus 로고
    • Trends in diet and Alzheimer’s disease during the nutrition transition in Japan and developing countries
    • COI: 1:CAS:528:DC%2BC3sXhvVGrs7fN
    • Grant WB (2014) Trends in diet and Alzheimer’s disease during the nutrition transition in Japan and developing countries. J Alzheimer’s Dis 38(3):611–620. doi:10.3233/JAD-130719
    • (2014) J Alzheimer’s Dis , vol.38 , Issue.3 , pp. 611-620
    • Grant, W.B.1


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