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Volumn 2, Issue 1, 2013, Pages 827-835

Multilocus genetic profiling to empower drug trials and predict brain atrophy

Author keywords

Alzheimer's disease; Brain atrophy; Clinical trial enrichment; Genetic risk score; Genetics; Neuroimaging

Indexed keywords

APOLIPOPROTEIN E;

EID: 84880276343     PISSN: None     EISSN: 22131582     Source Type: Journal    
DOI: 10.1016/j.nicl.2013.05.007     Document Type: Article
Times cited : (22)

References (62)
  • 2
    • 33845892752 scopus 로고    scopus 로고
    • Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
    • DOI 10.1038/ng1934, PII NG1934
    • L. Bertram, M.B. McQueen, K. Mullin, D. Blacker, and R.E. Tanzi Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database Nature Genetics 39 1 2007 17 23 (Pubitemid 46026496)
    • (2007) Nature Genetics , vol.39 , Issue.1 , pp. 17-23
    • Bertram, L.1    McQueen, M.B.2    Mullin, K.3    Blacker, D.4    Tanzi, R.E.5
  • 12
    • 77956231447 scopus 로고    scopus 로고
    • Effects of ApoE-epsilon4 allele load and age on the rates of grey matter and hippocampal volumes loss in a longitudinal cohort of 1186 healthy elderly persons
    • F. Crivello, H. Lemaître, C. Dufouil, B. Grassiot, N. Delcroix, N. Tzourio-Mazoyer, C. Tzourio, and B. Mazoyer Effects of ApoE-epsilon4 allele load and age on the rates of grey matter and hippocampal volumes loss in a longitudinal cohort of 1186 healthy elderly persons Neuroimage 53 3 2010 1064 1069
    • (2010) Neuroimage , vol.53 , Issue.3 , pp. 1064-1069
    • Crivello, F.1    Lemaître, H.2    Dufouil, C.3    Grassiot, B.4    Delcroix, N.5    Tzourio-Mazoyer, N.6    Tzourio, C.7    Mazoyer, B.8
  • 14
    • 71849098862 scopus 로고    scopus 로고
    • Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: A weighted genetic risk score
    • P.L. De Jager, L.B. Chibnik, J. Cui, J. Reischl, S. Lehr, K.C. Simon, C. Aubin, D. Bauer, J.F. Heubach, R. Sandbrink, M. Tyblova, P. Lelkova, Steering committee of the BENEFIT study, Steering committee of the BEYOND study, Steering committee of the LTF study, Steering committee of the CCR1 study, E. Havrdova, C. Pohl, D. Horakova, A. Ascherio, D.A. Hafler, and E.W. Karlson Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score Lancet Neurology 8 12 2009 1111 1119
    • (2009) Lancet Neurology , vol.8 , Issue.12 , pp. 1111-1119
    • De Jager, P.L.1    Chibnik, L.B.2    Cui, J.3    Reischl, J.4    Lehr, S.5    Simon, K.C.6    Aubin, C.7    Bauer, D.8    Heubach, J.F.9    Sandbrink, R.10    Tyblova, M.11    Lelkova, P.12
  • 28
    • 80052301716 scopus 로고    scopus 로고
    • Robust brain extraction across datasets and comparison with publicly available methods
    • J.E. Iglesias, C.Y. Liu, P.M. Thompson, and Z. Tu Robust brain extraction across datasets and comparison with publicly available methods IEEE Transactions on Medical Imaging 30 9 2011 1617 1634
    • (2011) IEEE Transactions on Medical Imaging , vol.30 , Issue.9 , pp. 1617-1634
    • Iglesias, J.E.1    Liu, C.Y.2    Thompson, P.M.3    Tu, Z.4
  • 29
    • 0036527287 scopus 로고    scopus 로고
    • Ethical perspectives on pharmacogenomic profiling in the drug development process
    • A.M. Issa Ethical perspectives on pharmacogenomic profiling in the drug development process Nature Reviews. Drug Discovery 1 4 2002 300 308 (Pubitemid 37361446)
    • (2002) Nature Reviews Drug Discovery , vol.1 , Issue.4 , pp. 300-308
    • Issa, A.M.1
  • 34
    • 85018446662 scopus 로고    scopus 로고
    • Alzheimer disease: BIN1 variant increases risk of Alzheimer disease through tau
    • K. Kingwell Alzheimer disease: BIN1 variant increases risk of Alzheimer disease through tau Nature Reviews. Neurology 9 4 2013 184
    • (2013) Nature Reviews. Neurology , vol.9 , Issue.4 , pp. 184
    • Kingwell, K.1
  • 36
    • 84875514732 scopus 로고    scopus 로고
    • Regulatory innovation and drug development for early-stage Alzheimer's disease
    • N. Kozauer, and R. Katz Regulatory innovation and drug development for early-stage Alzheimer's disease The New England Journal of Medicine 368 13 2013 1169 1171
    • (2013) The New England Journal of Medicine , vol.368 , Issue.13 , pp. 1169-1171
    • Kozauer, N.1    Katz, R.2
  • 39
    • 34548775692 scopus 로고    scopus 로고
    • Enhanced signal detection in neuroimaging by means of regional control of the global false discovery rate
    • DOI 10.1016/j.neuroimage.2007.07.031, PII S1053811907006775
    • D.R.M. Langers, J.F.A. Jansen, and W.H. Backes Enhanced signal detection in neuroimaging by means of regional control of the global false discovery rate NeuroImage 38 1 2007 43 56 (Pubitemid 47429996)
    • (2007) NeuroImage , vol.38 , Issue.1 , pp. 43-56
    • Langers, D.R.M.1    Jansen, J.F.A.2    Backes, W.H.3
  • 40
    • 33750965356 scopus 로고    scopus 로고
    • Inverse consistent mapping in 3D deformable image registration: Its construction and statistical properties
    • Information Processing in Medical Imaging: 19th International Conference, IPMI 2005. Proceedings
    • A. Leow, S.C. Huang, A. Geng, J. Becker, S. Davis, A. Toga, and P.M. Thompson Inverse consistent mapping in 3D deformable image registration: its construction and statistical properties Information Processing in Medical Imaging 19 2005 493 503 (Pubitemid 41425340)
    • (2005) Lecture Notes in Computer Science , vol.3565 , pp. 493-503
    • Leow, A.1    Huang, S.-C.2    Geng, A.3    Becker, J.4    Davis, S.5    Toga, A.6    Thompson, P.7
  • 42
    • 77952879255 scopus 로고    scopus 로고
    • Automated cross-sectional and longitudinal hippocampal volume measurement in mild cognitive impairment and Alzheimer's disease
    • The Alzheimer'S Disease Neuroimaging Initiative
    • K.K. Leung, J. Barnes, G.R. Ridgway, J.W. Bartlett, M.J. Clarkson, K. Macdonald, N. Schuff, N.C. Fox, S. Ourselin, and for the Alzheimer's Disease Neuroimaging Initiative Automated cross-sectional and longitudinal hippocampal volume measurement in mild cognitive impairment and Alzheimer's disease NeuroImage 51 4 2010 1345 1359
    • (2010) NeuroImage , vol.51 , Issue.4 , pp. 1345-1359
    • Leung, K.K.1    Barnes, J.2    Ridgway, G.R.3    Bartlett, J.W.4    Clarkson, M.J.5    Macdonald, K.6    Schuff, N.7    Fox, N.C.8    Ourselin, S.9
  • 43
    • 77954028812 scopus 로고    scopus 로고
    • Enrichment through biomarkers in clinical trials of Alzheimer's drugs in patients with mild cognitive impairment
    • The Alzheimer'S Disease Neuroimaging Initiative
    • M. Lorenzi, M. Donohue, D. Paternicò, C. Scarpazza, S. Ostrowitzki, O. Blin, E. Irving, G.B. Frisoni, and for the Alzheimer's Disease Neuroimaging Initiative Enrichment through biomarkers in clinical trials of Alzheimer's drugs in patients with mild cognitive impairment Neurobiology of Aging 31 8 2010 1443 1451
    • (2010) Neurobiology of Aging , vol.31 , Issue.8 , pp. 1443-1451
    • Lorenzi, M.1    Donohue, M.2    Paternicò, D.3    Scarpazza, C.4    Ostrowitzki, S.5    Blin, O.6    Irving, E.7    Frisoni, G.B.8
  • 45
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
    • G. McKhann, D. Drachman, M. Folstein, R. Katzman, D. Price, and E.M. Stadlan Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease Neurology 34 7 1984 939 944 (Pubitemid 14076461)
    • (1984) Neurology , vol.34 , Issue.7 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 46
    • 0027425211 scopus 로고
    • The Clinical Dementia Rating (CDR): Current version and scoring rules
    • J.C. Morris The Clinical Dementia Rating (CDR). Current version and scoring rules Neurology 43 11 1993 2412 2414 (Pubitemid 23346995)
    • (1993) Neurology , vol.43 , Issue.11 , pp. 2412-2414
    • Morris, J.C.1
  • 49
    • 50849121987 scopus 로고    scopus 로고
    • Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database
    • S.M. Nestor, R. Rupsingh, M. Borrie, M. Smith, V. Accomazzi, J.L. Wells, J. Fogarty, R. Bartha, and Alzheimer's Disease Neuroimaging Initiative Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database Brain 131 9 2008 2443 2454
    • (2008) Brain , vol.131 , Issue.9 , pp. 2443-2454
    • Nestor, S.M.1    Rupsingh, R.2    Borrie, M.3    Smith, M.4    Accomazzi, V.5    Wells, J.L.6    Fogarty, J.7    Bartha, R.8    Disease Neuroimaging Initiative, A.9
  • 53
    • 57649131090 scopus 로고    scopus 로고
    • The medical and economic roles of pipeline pharmacogenetics: Alzheimer's disease as a model of efficacy and HLA-B(*)5701 as a model of safety
    • A.D. Roses The medical and economic roles of pipeline pharmacogenetics: Alzheimer's disease as a model of efficacy and HLA-B(*)5701 as a model of safety Neuropsychopharmacology 34 1 2009 6 17
    • (2009) Neuropsychopharmacology , vol.34 , Issue.1 , pp. 6-17
    • Roses, A.D.1
  • 56
    • 77951286625 scopus 로고    scopus 로고
    • Genotype-based risk and pharmacogenetic sampling in clinical trials
    • N.J. Schork, and E.J. Topol Genotype-based risk and pharmacogenetic sampling in clinical trials Journal of Biopharmaceutical Statistics 20 2 2010 315 333
    • (2010) Journal of Biopharmaceutical Statistics , vol.20 , Issue.2 , pp. 315-333
    • Schork, N.J.1    Topol, E.J.2
  • 57
    • 0031987382 scopus 로고    scopus 로고
    • A nonparametric method for automatic correction of intensity nonuniformity in mri data
    • PII S0278006298031516
    • J.G. Sled, A.P. Zijdenbos, and A.C. Evans A nonparametric method for automatic correction of intensity nonuniformity in MRI data IEEE Transactions on Medical Imaging 17 1 1998 87 97 (Pubitemid 128742012)
    • (1998) IEEE Transactions on Medical Imaging , vol.17 , Issue.1 , pp. 87-97
    • Sied, J.G.1    Zijdenbos, A.P.2    Evans, A.C.3
  • 60
    • 25444442819 scopus 로고    scopus 로고
    • Do MCI criteria in drug trials accurately identify subjects with predementia Alzheimer's disease?
    • DOI 10.1136/jnnp.2004.047720
    • P.J. Visser, P. Scheltens, and F.R. Verhey Do MCI criteria in drug trials accurately identify subjects with predementia Alzheimer's disease? J Neurol Neurosurg Psychiatry 76 10 2005 1348 1354 (Pubitemid 41360969)
    • (2005) Journal of Neurology, Neurosurgery and Psychiatry , vol.76 , Issue.10 , pp. 1348-1354
    • Visser, P.J.1    Scheltens, P.2    Verhey, F.R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.