Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood

Human Molecular Genetics

Volumn 24, Issue 13, 2015, Pages 3792-3813

  Rönn, Tina ^a   Volkov, Petr ^a   Gillberg, Linn ^b,c   Kokosar, Milana ^d   Perfilyev, Alexander ^a   Jacobsen, Anna Louisa ^b   Jørgensen, Sine W ^b,e   Brøns, Charlotte ^b   Jansson, Per Anders ^f   Eriksson, Karl Fredrik ^g   Pedersen, Oluf ^h   Hansen, Torben ^h   Groop, Leif ^a   Stener Victorin, Elisabet ^d,i   Vaag, Allan ^b,c   Nilsson, Emma ^a,b   Ling, Charlotte ^a  

^a LUND UNIVERSITY DIABETES CENTRE   (Sweden)

^b International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d UNIVERSITY OF GOTHENBURG   (Sweden)

^e STENO DIABETES CENTER   (Denmark)

^f UNIVERSITY OF GOTHENBURG   (Sweden)

^g LUND UNIVERSITY   (Sweden)

^h University of Copenhagen   (Denmark)

ⁱ KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; GLUCOSE; HEMOGLOBIN A1C; HLA A2 ANTIGEN; HLA DPB1 ANTIGEN; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ADIPOSE TISSUE; ADULT; AGE DISTRIBUTION; AGED; AMINO ACID METABOLISM; ARTICLE; BODY MASS; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ENERGY METABOLISM; EPIGENETICS; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HUMAN; HUMAN TISSUE; LIPID METABOLISM; MALE; NEOPLASM; NON COMMUNICABLE DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; QUALITY CONTROL; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SEX DIFFERENCE; SIGNAL TRANSDUCTION; TARGET ORGAN; VERY ELDERLY; Y CHROMOSOME; AGE; BLOOD; CAUCASIAN; COHORT ANALYSIS; DENMARK; GENETICS; GENOME-WIDE ASSOCIATION STUDY; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; SWEDEN; YOUNG ADULT;

ADIPOSE TISSUE; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BIOMARKERS; BODY MASS INDEX; COHORT STUDIES; CPG ISLANDS; DENMARK; DIABETES MELLITUS, TYPE 2; DNA METHYLATION; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; MALE; MIDDLE AGED; SWEDEN; YOUNG ADULT;

EID: 84936777834     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv124     Document Type: Article

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