Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: A pooled analysis of 97 prospective cohorts with 1·8 million participants

The Lancet

Volumn 383, Issue 9921, 2014, Pages 970-983

  Lu, Yuan ^a   Hajifathalian, Kaveh ^a   Ezzati, Majid ^b   Woodward, Mark ^c,cq   Rimm, Eric B ^d   Danaei, Goodarz ^a   Selmer, Randi ^e   Strand, Bjorn H ^e   Dobson, A ^cq   Hozawa, A ^cq   Nozaki, A ^cq   Okayama, Akira ^bl,cq   Rodgers, A ^cq   Tamakoshi, A ^cq   Zhou, B F ^cq   Zhou, B ^cq   Yao, C H ^cq   Jiang, C Q ^cq   Gu, D F ^cq   Heng, D ^cq   Giles, Graham G ^bh,cq   Shan, G L ^cq   Whitlock, G ^cq   Arima, H ^cq   Kim, H C ^cq   Christensen, H ^cq   Horibe, H ^cq   Maegawa, H ^cq   Tanaka, H ^cq   Ueshima, Hirotsugu ^bm,cq   Zhang, H Y ^cq   Kim, I S ^cq   Suh, I ^cq   Fuh, J L ^cq   Lee, J ^cq   Woo, Jean ^av,cq   Xie, J X ^cq   Zhou, J ^cq   Hughes, K ^cq   Jamrozik, K ^cq   Nakachi, K ^cq   Sakata, K ^cq   Shimamoto, K ^cq   Chen, L Q ^cq   Liu, L S ^cq   Hobbs, M ^cq   Iida, M ^cq   Kagaya, M ^cq   Divitini, Mark L ^o,cq   Luszcz, M ^cq   Nakamura, M ^cq   Huang, M S ^cq   Knuiman, Matthew W ^o,cq   Aoki, N ^cq   Norman, P ^cq   Sritara, P ^cq   Yang, Q D ^cq   Broadhurst, R ^cq   Huxley, R ^cq   Jackson, R ^cq   Norton, R ^cq   Ameratunga, S ^cq   Ho, S C ^cq   Li, S C ^cq   Jee, S H ^cq   Chew, S K ^cq   Macmahon, S ^cq   Choudhury, S R ^cq   Saitoh, S ^cq   Yao, S X ^cq   Welborn, Timothy A ^o,cq   Lam, T H ^cq   Hashimoto, T ^cq   Ohkubo, T ^cq   Pan, Wen Harn ^q,r,cq   Duan, X F ^cq   Fang, X ^cq   Wu, X G ^cq   Fang, X H ^cq   Yu, X H ^cq   Li, Y H ^cq   He, Y ^cq   Imai, Y ^cq   Kita, Y ^cq   Kiyohara, Yutaka ^aw,cq   Matsutani, Y ^cq   Hong, Z ^cq   Wu, Z L ^cq   Chen, Z M ^cq   Wu, Z S ^cq   Tang, Z ^cq   Li, Z Z ^cq   Parker, Emily D ^f   Pereira, Mark A ^g   Stevens, June ^h   Panagiotakos, Demosthenes B ⁱ   Pitsavos, Christos ^j   Attia, John R ^k   D’este, Catherine A ^k   Zhang, Xiaofei ^l,m   Clays, Els ⁿ   De Bacquer, Dirk A O ⁿ   Van Herck, Koen ⁿ   Morrison, Howard I ^p   Wang, Feng ^p   Chuang, Shao Yuan ^q   Yeh, Wen Ting ^r   Chen, Zhengming ^s   Smith, Margaret C ^s   Zhou, Maigeng ^t   Wang, Wei ^u   Zhang, Xiao Ting ^u   Zhao, Dong ^u   Vollset, Stein Emil ^e   Fuchs, Sandra C ^v   Fuchs, Flavio D ^w   Moreira, Leila B ^v   Dontas, Ismene A ^j   Dontas, Cleo A ^x   Kafatos, Anthony G ^y   Moschandreas, Joanna ^y   Lanti, Mariapaola ^z   Menotti, Alessandro ^z   Kromhout, Daan ^aa   Jensen, Majken K ^a   Overvad, Kim ^ab,ac   Tjonneland, Anne ^ad   Klotsche, Jens ^ae   Wittchen, Hans Ulrich ^ae   Fischer, Sabine ^ae   Hanefeld, Markolf ^ae   Schwanebeck, Uta ^af   Simons, Leon A ^ag   Simons, Judith ^ah   Bender, Ralf ^ai   Matthies, Silke ^aj   Nissinen, Aulikki ^ak   Tolonen, Hanna K ^ak   Tuomilehto, Jaakko ^ak,al,am,an   Chaturvedi, Nish ^ao   Fuller, John H ^ap   Soedamah Muthu, Sabita S ^aa   Kotseva, Kornelia ^ao   Wood, David A ^ao   Bots, Michiel L ^aq   Moons, Karel G M ^aq   Heliovaara, Markku ^ak   Knekt, Paul B ^ak   Rissanen, Harri ^ak   Ferrie, Jane E ^ar   Shipley, Martin J ^ar   Smith, George Davey ^as   Johansson, Saga ^at   Lappas, Georgios ^au   Rosengren, Annika ^au   Sham, Aprille ^av   Yu, Ruby HY ^av   Hata, Jun ^aw   Ninomiya, Toshiharu ^aw   Hoshide, Satoshi ^ax   Kario, Kazuomi ^ax   Rastenyte, Daiva ^ay   Tamosiunas, Abdonas ^ay   de Simone, Giovanni ^az   Devereux, Richard B ^ba   Gerdts, Eva ^bb   Colquhoun, David M ^bc   Keech, Anthony C ^bd   Kirby, Adrienne C ^bd   Mizuno, Kyoichi ^be   Nakamura, Haruo ^bf   Uchiyama, Shinichiro ^bg   Bassett, Julie K ^bh   Hodge, Allison M ^bh   Wilhelmsen, Lars ^bi   Dhaliwal, Satvinder S ^bj   Nakamura, Yasuyuki ^bk   Kadota, Aya ^bn   Okamura, Tomonori ^bo   Sandvei, Marie S ^bp,bq   Vatten, Lars J ^bp   Vik, Anne ^br   Morkedal, Bjorn ^bp   Romundstad, Pal R ^bp   Elkind, Mitchell SV ^bs   Gardener, Hannah ^bt   Sacco, Ralph L ^bt   Mignano, Antonino ^bu   Novo, Salvatore ^bu   Rizzo, Manfredi ^bv   Assmann, Gerd ^bw   Schulte, Helmut ^bw   Lissner, Lauren ^bi   Skoog, Ingmar ^bi   Sundh, Valter ^bi   Marin, Alejandro ^bx   Medrano, Maria Jose ^by   Hofman, Albert ^bz   Kuningas, Maris ^bz   Stricker, Bruno H ^bz   van der Graaf, Yolanda ^aq   Visseren, Frank LJ ^aq   Lee, Jeannette JM ^ca   Bemelmans, Wanda ^cb   de Groot, Lisette C P G M ^aa   de Hollander, Ellen L ^aa,cb   Adachi, Hisashi ^cc   Hirai, Yuji ^cc   Azizi, Fereidoun ^cd   Hadaegh, Farzad ^ce   Khalili, Davood ^ce   Mathiesen, Ellisiv B ^cf   Njolstad, Inger ^cf   Wilsgaard, Tom ^cf   Can, Gunay ^cg   Onat, Altan ^cg   Arnlov, Johan ^ch   Sundstrom, Johan ^ci   Blackburn, Henry W ^cj   Jacobs, David R ^cj   Averna, Maurizio R ^bv   Cefalu, Angelo B ^bv   Noto, Davide ^bv   Concin, Hans ^ck   Nagel, Gabriele ^ck,cl   Ulmer, Hanno ^cm   Krasnow, Ruth E ^cn   Swan, Gary E ^cn   Kivimaki, Mika ^ar   David Batty, G ^ar   Milic, Natasa ^co   Ostojic, Miodrag C ^co   Parapid, Biljana ^cp   Geleijnse, Johanna M ^aa   Waterham, Eveline ^aa   Feskens, Edith J ^aa   more..

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c GEORGE INSTITUTE FOR GLOBAL HEALTH   (Australia)

^d HARVARD MEDICAL SCHOOL   (United States)

^e NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^f HEALTHPARTNERS INSTITUTE   (United States)

^g UNIVERSITY OF MINNESOTA   (United States)

^h UNIVERSITY OF NORTH CAROLINA   (United States)

ⁱ HAROKOPIO UNIVERSITY   (Greece)

^j UNIVERSITY OF ATHENS   (Greece)

^k UNIVERSITY OF NEWCASTLE   (Australia)

^l ZHEJIANG UNIVERSITY   (China)

^m FUWAI HOSPITAL   (China)

ⁿ GHENT UNIVERSITY   (Belgium)

^o UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^p PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^q NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^r INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^s UNIVERSITY OF OXFORD   (United Kingdom)

^t CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^u CAPITAL MEDICAL UNIVERSITY   (China)

^v FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^w HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^x the National Institute for Science and Technology for Health Technology Assessment ^*  (Greece)

^y UNIVERSITY OF CRETE   (Greece)

^z Association for Cardiac Research   (Italy)

^aa WAGENINGEN UNIVERSITY   (Netherlands)

^ab AARHUS UNIVERSITY   (Denmark)

^ac AALBORG UNIVERSITY HOSPITAL   (Denmark)

^ad DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^ae DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^af Power Electronics Research Group   (Germany)

^ag UNIVERSITY OF NEW SOUTH WALES   (Australia)

^ah ST VINCENT S HOSPITAL   (Australia)

^ai INSTITUTE FOR QUALITY AND EFFICIENCY IN HEALTH CARE IQWIG   (Germany)

^aj UNIVERSITY OF APPLIED SCIENCES KOBLENZ   (Germany)

^ak NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^al DANUBE UNIVERSITY KREMS   (Austria)

^am INSTITUTO DE INVESTIGACIÓN SANITARIA DEL HOSPITAL CLÍNICO SAN CARLOS IDISSC   (Spain)

^an KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^ao NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^ap ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^aq UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^ar UNIVERSITY COLLEGE LONDON   (United Kingdom)

^as UNIVERSITY OF BRISTOL   (United Kingdom)

^at ASTRAZENECA R AND D   (Sweden)

^au UNIVERSITY OF GOTHENBURG   (Sweden)

^av CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^aw KYUSHU UNIVERSITY   (Japan)

^ax JICHI MEDICAL UNIVERSITY   (Japan)

^ay LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

^az UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^ba NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^bb UNIVERSITY OF BERGEN   (Norway)

^bc UNIVERSITY OF QUEENSLAND   (Australia)

^bd UNIVERSITY OF SYDNEY   (Australia)

^be Nippon University School of Medicine   (Japan)

^bf Mitsukoshi Health and Welfare Foundation   (Japan)

^bg Tokyo Womenâs Medical University   (Japan)

^bh CANCER EPIDEMIOLOGY CENTRE   (Australia)

^bi UNIVERSITY OF GOTHENBURG   (Sweden)

^bj CURTIN UNIVERSITY   (Australia)

^bk Kyoto Womenâ s University   (Japan)

^bl FUKUJUJI HOSPITAL   (Japan)

^bm SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^bn OSAKA KYOIKU UNIVERSITY   (Japan)

^bo KEIO UNIVERSITY   (Japan)

^bp NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^bq Nordland Hospital Bodà   (Norway)

^br TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^bs Osaka Kyoiku University ^*  (United States)

^bt UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^bu UNIVERSITY OF PALERMO   (Italy)

^bv UNIVERSITY OF PALERMO   (Italy)

^bw Assmann Foundation for Prevention   (Germany)

^bx Centro de Salud Fuente Norte   (Spain)

^by CARLOS III INSTITUTE OF HEALTH   (Spain)

^bz ERASMUS MEDICAL CENTER   (Netherlands)

^ca NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^cb NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^cc KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^cd SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^ce SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^cf UNIVERSITY OF TROMSØ   (Norway)

^cg ISTANBUL UNIVERSITY   (Turkey)

^ch UPPSALA UNIVERSITY   (Sweden)

^ci UPPSALA UNIVERSITY   (Sweden)

^cj UNIVERSITY OF MINNESOTA   (United States)

^ck AGENCY FOR PREVENTIVE AND SOCIAL MEDICINE   (Austria)

^cl UNIVERSITY OF ULM   (Germany)

^cm INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^cn SRI INTERNATIONAL   (United States)

^co UNIVERSITY OF BELGRADE   (Serbia)

^cp CLINICAL CENTER OF SERBIA   (Serbia)

^cq University of Minnesota School of Public Health ^*

more..

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ARTICLE; ASIAN; AUSTRALIA; BLOOD PRESSURE; BODY MASS; CEREBROVASCULAR ACCIDENT; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; GEOGRAPHIC DISTRIBUTION; GLUCOSE BLOOD LEVEL; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; NORTH AMERICA; OBESITY; PRIORITY JOURNAL; RISK ASSESSMENT; RISK REDUCTION; WESTERN EUROPE; ADULT; AGE DISTRIBUTION; BLOOD PRESSURE MONITORING; CARDIOVASCULAR RISK; CAUSE OF DEATH; DIABETES MELLITUS; DISEASE ASSOCIATION; FOLLOW UP; HYPERCHOLESTEROLEMIA; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; PREVALENCE; PROSPECTIVE STUDY; RISK FACTOR; SEX DIFFERENCE; SYSTEMATIC REVIEW (TOPIC); SYSTOLIC BLOOD PRESSURE; WAIST CIRCUMFERENCE; WAIST HIP RATIO;

BIOLOGICAL MARKERS; BLOOD GLUCOSE; BLOOD PRESSURE; BODY MASS INDEX; CHOLESTEROL; CORONARY DISEASE; HUMANS; OBESITY; OVERWEIGHT; RISK FACTORS; STROKE;

EID: 84896134029     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(13)61836-X     Document Type: Article

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