Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape

Genome Biology

Volumn 14, Issue 9, 2013, Pages

  Day, Kenneth ^a   Waite, Lindsay L ^a   Thalacker Mercer, Anna ^b,d   West, Andrew ^c,e   Bamman, Marcas M ^b,d,e   Brooks, James D ^f   Myers, Richard M ^a   Absher, Devin ^a  

^a HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Blood; Brain; Chromatin; H3K27Me3; Kidney; LADs; Methylation; Muscle; Sequencing

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; CCCTC-BINDING FACTOR; CHROMATIN; HISTONE; PROTEIN BINDING; REPRESSOR PROTEIN;

AGE; ARTICLE; BINDING SITE; BLOOD; BRAIN TISSUE; CHROMATIN; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENETIC DRIFT; HUMAN; HUMAN TISSUE; KIDNEY PARENCHYMA; MUSCLE FIBER CONTRACTION; NUCLEOTIDE SEQUENCE; SKELETAL MUSCLE; TISSUE SPECIFICITY; ADULT; AGED; AGING; ANTIBODY SPECIFICITY; BRAIN; CHEMISTRY; DNA MICROARRAY; DNA SEQUENCE; FEMALE; GENETIC EPIGENESIS; GENETICS; KIDNEY; MALE; METABOLISM; MIDDLE AGED; PROTEIN DOMAIN; TISSUE MICROARRAY;

ADULT; AGED; AGING; BINDING SITES; BRAIN; CHROMATIN; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; HISTONES; HUMANS; KIDNEY; MALE; MIDDLE AGED; MUSCLE, SKELETAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SPECIFICITY; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; REPRESSOR PROTEINS; SEQUENCE ANALYSIS, DNA; TISSUE ARRAY ANALYSIS;

EID: 84883727941     PISSN: None     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2013-14-9-r102     Document Type: Article

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