Hemoglobin A1c in nondiabetic patients: An independent predictor of coronary artery disease and its severity

Mayo Clinic Proceedings

Volumn 89, Issue 7, 2014, Pages 908-916

  Garg, Naveen ^a   Moorthy, Nagaraja ^a,b   Kapoor, Aditya ^a   Tewari, Satyendra ^a   Kumar, Sudeep ^a   Sinha, Archana ^a   Shrivastava, Anshika ^a   Goel, Pravin K ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^b SRI JAYADEVA INSTITUTE OF CARDIOVASCULAR SCIENCES AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE DISTRIBUTION; ALGORITHM; APGAR SCORE; ARTICLE; ASTHMA; ASTHMA APGAR SYSTEM; ASTHMA CONTROL TEST; BLACK PERSON; CHILD; CHILDHOOD ASTHMA CONTROL TEST; CLINICAL ASSESSMENT TOOL; CLINICAL TRIAL (TOPIC); COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION COEFFICIENT; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PASSIVE SMOKING; PRIMARY MEDICAL CARE; QUALITY OF LIFE; QUESTIONNAIRE; SCHOOL CHILD; SCORING SYSTEM; SMOKING;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDIES; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX;

EID: 84904652220     PISSN: 00256196     EISSN: 19425546     Source Type: Journal    
DOI: 10.1016/j.mayocp.2014.03.017     Document Type: Article

References (36)

1. Marshall SM, Barth JH. Standardization of HbA1c measurements: a consensus statement. Diabet Med. 2000;17(1):5-6.
2. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2011;34(suppl 1):S62-S69.
3. Meigs JB, Nathan DM, Cupples LA, Wilson PW, Singer DE. Tracking of glycated hemoglobin in the original cohort of the Framingham Heart Study. J Clin Epidemiol. 1996;49(40): 411-417.
4. Stolar M. Glycemic control and complications in type 2 diabetes mellitus. Am J Med. 2010;123(3 suppl):S3-S11.
5. Selvin E, Coresh J, Golden SH, Brancati FL, Folsom AR, Steffes MW. Glycemic control and coronary heart disease risk in persons with and without diabetes: the Atherosclerosis Risk in Communities study. Arch Intern Med. 2005;165(16): 1910-1916.
6. Khaw KT, Wareham N, Luben R, et al. Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of European prospective investigation of cancer and nutrition (EPIC Norfolk). BMJ. 2001;322(7277):15-18.
7. Huang Y, Bi Y, Wang W, Xu M, Xu Y, Li M, Wang T, Chen Y, Li X, Ning G. Glycated hemoglobin A1c, fasting plasma glucose, and two-hour post challenge plasma glucose levels in relation to carotid intima-media thickness in Chinese with normal glucose tolerance. J Clin Endocrinol Metab. 2011;96(9):E1461-E1465.
8. Jorgensen L, Jenssen T, Joakimsen O, Heuch I, Ingebretsen OC, Jacobsen BK. Glycated hemoglobin level is strongly related to the prevalence of carotid artery plaques with high echogenicity in nondiabetic individuals: the Tromso Study. Circulation. 2004; 110(4):466-470.
9. Selvin E, Steffes MW, Zhu H, Matsushita K, Wagenknecht L, Pankow J, Coresh J, Brancati FL. Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N Engl J Med. 2010;362(9):800-811.
10. Park S, Barrett-Connor E, Wingard DL, Shan J, Edelstein S. GHb is a better predictor of cardiovascular disease than fasting or postchallenge plasma glucose in women without diabetes: the Rancho Bernardo Study. Diabetes Care. 1996;1(5):450-456.
11. de Vegt F, Dekker JM, Ruhe HG, et al. Hyperglycemia is associated with all-cause and cardiovascular mortality in the Hoorn population: the Hoorn study. Diabetologia. 1999;42(8):926-931.
12. Pradhan AD, Rifai N, Buring JE, Ridker PM. Hemoglobin A1c predicts diabetes but not cardiovascular disease in nondiabetic women. Am J Med. 2007;120(8):720-727.
13. Meigs JB, Nathan DM, D'Agostino RB, Wilson PWF. Fasting and postchallenge glycemia and cardiovascular risk: the Framingham Offspring Study. Diabetes Care. 2002;25(10):1845-1850.
14. Lenfant C, Chobanian AV, Jones DW, Roccella EJ; Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Seventh report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7): resetting the hypertension sails. Hypertension. 2003;41(6):1178-1179.
15. Nelson DE, Powell-Griner E, Town M, Kovar MG. A comparison of national estimates from the National Health Interview Survey and the Behavioral Risk Factor Surveillance System. Am J Public Health. 2003;93(8):1335-1341.
16. Greene T, Bourgoignie JJ, Habwe V, et al. Baseline characteristics in the Modification of Diet in Renal Disease Study. J Am Soc Nephrol. 1993;4(5):1221-1236.
17. Sianos G, Morel MA, Kappetein AP, et al. The SYNTAX score: an angiographic tool grading the complexity of coronary artery disease. Eurointervention. 2005;1(2):219-227.
18. Sarwar N, Gao P, Seshasai SR, et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 2010;375(9733):2215-2222.
19. Stratton IM, Adler AI, Neil HA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ. 2000;321(7258):405-412.
20. Selvin E, Marinopoulos S, Berkenblit G, et al. Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitus. Ann Intern Med. 2004;141(6):421-431.
21. Chowdhury TA, Lasker SS. Elevated glycated hemoglobin in non-diabetic patients is associated with an increased mortality in myocardial infarction. Postgrad Med J. 1998;74(874):480-481.
22. Vitelli LL, Shahar E, Heiss G, et al. Glycosylated hemoglobin level and carotid intimal-medial thickening in nondiabetic individuals: the Atherosclerosis Risk in Communities Study. Diabetes Care. 1997;20(9):1454-1458.
23. Sander D, Schulze-Horn C, Bickel H, Gnahn H, Bartels E, Conrad B. Combined effects of hemoglobin A1c and C-reactive protein on the progression of subclinical carotid atherosclerosis: the INVADE study. Stroke. 2006;37(2): 351-357.
24. Rubin J, Matsushita K, Ballantyne CM, Hoogeveen R, Coresh J, Selvin E. Chronic hyperglycemia and subclinical myocardial injury. J Am Coll Cardiol. 2012;59(5):484-489.
25. The DECODE Study Group. Is the current definition for diabetes relevant to mortality risk from all causes and cardiovascular and noncardiovascular diseases? Diabetes Care. 2003;26(3): 688-696.
26. Khaw KT, Wareham N, Bingham S, Luben R, Welch A, Day N. Association of hemoglobin A1c with cardiovascular disease and mortality in adults: the European prospective investigation into cancer in Norfolk. Ann Intern Med. 2004; 141(6):413-420.
27. Kaneto H, Katakami N, Matsuhisa M, Matsouka T. Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis. Mediators Inflamm. 2010;2010:453892.
28. Brownlee M. Lilly Lecture 1993: glycation and diabetic complications. Diabetes. 1994;43(6):836-841.
29. Aronson D, Rayfield EJ. How hyperglycemia promotes atherosclerosis: molecular mechanisms. Cardiovasc Diabetol. 2002;1:1.
30. Magnuson EA, Farkouh ME, Fuster V, et al. Cost-effectiveness of percutaneous coronary intervention with drug eluting stents versus bypass surgery for patients with diabetes and multivessel coronary artery disease: results from the FREEDOM trial. Circulation. 2013;127(7):820-831.
31. Hosomi N, Noma T, Ohyama H, Takahashi T, Kohno M. Vascular proliferation and transforming growth factor-beta expression in pre- and early stage of diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats. Atherosclerosis. 2002;162(1): 69-76.
32. Sarwar N, Aspelund T, Eiriksdottir G, et al. Markers of dysglycaemia and risk of coronary heart disease in people without diabetes: Reykjavik prospective study and systematic review. PLoS Med. 2010;7(5):e1000278.
33. O'Keefe JH, Bell DS. Postprandial hyperglycemia/hyperlipidemia (postprandial dysmetabolism) is a cardiovascular risk factor. Am J Cardiol. 2007;100(5):899-904.
34. Hu BF. Prevention of diabetes and cardiovascular disease among prediabetic individuals: lifestyle versus drug interventions. Eur J Cardiovasc Prev Rehabil. 2011;18(6):810-812.
35. Mellbin GL, Anselmino M, Lars R. Diabetes, prediabetes and cardiovascular risk. Eur J Cardiovasc Prev Rehabil. 2010;17(1): s9-s14.
36. Hage C, Lundman P, Rydén L, Mellbin L. Fasting glucose, HbA1c, or oral glucose tolerance testing for the detection of glucose abnormalities in patients with acute coronary syndromes. Eur J Prev Cardiol. 2013;20(4):549-554.