Young men with low birthweight exhibit decreased plasticity of genome-wide muscle DNA methylation by high-fat overfeeding

Diabetologia

Volumn 57, Issue 6, 2014, Pages 1154-1158

  Jacobsen, Stine C ^a,b,c   Gillberg, Linn ^a,b   Bork Jensen, Jette ^a,b,c   Ribel Madsen, Rasmus ^b,c   Lara, Ester ^d   Calvanese, Vincenzo ^d   Ling, Charlotte ^e   Fernandez, Agustin F ^f   Fraga, Mario F ^d,f   Poulsen, Pernille ^c   Brøns, Charlotte ^a,b,c   Vaag, Allan ^a,b,c  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c STENO DIABETES CENTER   (Denmark)

^d CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^e LUND UNIVERSITY   (Sweden)

^f DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

DNA methylation; Epigenetics; High fat overfeeding; Insulin resistance; Low birthweight; Skeletal muscle; Type 2 diabetes

Indexed keywords

DNA; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B;

ADULT; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; GENOME ANALYSIS; HUMAN; LIPID DIET; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OVERNUTRITION; PHENOTYPIC PLASTICITY; PRIORITY JOURNAL; PROMOTER REGION; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; SKELETAL MUSCLE; GENETIC EPIGENESIS; GENETICS; INSULIN RESISTANCE; METABOLISM; PHYSIOLOGY; YOUNG ADULT;

ADULT; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EPIGENESIS, GENETIC; HUMANS; INFANT, LOW BIRTH WEIGHT; INSULIN RESISTANCE; MALE; MUSCLE, SKELETAL; YOUNG ADULT;

EID: 84901188568     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3198-8     Document Type: Article

References (10)

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