Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs

Age

Volumn 36, Issue 3, 2014, Pages 1523-1540

  Steegenga, Wilma T ^a   Boekschoten, Mark V ^a   Lute, Carolien ^a   Hooiveld, Guido J ^a   De Groot, Philip J ^a   Morris, Tiffany J ^b   Teschendorff, Andrew E ^b   Butcher, Lee M ^b   Beck, Stephan ^b   Müller, Michael ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

DNA methylation; Epigenetic biomarkers of aging; Epigenetics; Gene expression; Molecular aging; PBMCs

Indexed keywords

CELL PROTEIN; DNA; GENOMIC DNA; PIRINIXIC ACID; PROTEIN ELOVL2; PROTEIN FHL2; PROTEIN KLF14; PROTEIN PENK; RNA; UNCLASSIFIED DRUG;

ADULT; AGED; AGING; ARTICLE; BIOINFORMATICS; CARCINOGENESIS; CELL CULTURE; CELL ISOLATION; CONTROLLED STUDY; CPG ISLAND; CYTOLOGY; DEVELOPMENT; DNA METHYLATION; EPIGENETICS; FEASIBILITY STUDY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INDUCTION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC EPIGENESIS; GENETICS; GENOME ANALYSIS; HUMAN; HUMAN CELL; HUMAN GENOME; MALE; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; TRANSIENT EXPRESSION;

ADULT; AGED; AGING; CELLS, CULTURED; CYTOLOGY; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETICS; GENOME, HUMAN; HEALTHY VOLUNTEERS; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; METABOLISM; MIDDLE AGED; RNA;

EID: 84905379002     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-014-9648-x     Document Type: Article

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