-
1
-
-
71449125977
-
Forcing cells to change lineages
-
Graf T, Enver T (2009) Forcing cells to change lineages. Nature 462(7273):587-594
-
(2009)
Nature
, vol.462
, Issue.7273
, pp. 587-594
-
-
Graf, T.1
Enver, T.2
-
2
-
-
79958252915
-
Chromatin connections to pluripotency and cellular reprogramming
-
Orkin SH, Hochedlinger K (2011) Chromatin connections to pluripotency and cellular reprogramming. Cell 145(6):835-850
-
(2011)
Cell
, vol.145
, Issue.6
, pp. 835-850
-
-
Orkin, S.H.1
Hochedlinger, K.2
-
3
-
-
79958175738
-
Epigenomics of human embryonic stem cells and induced pluripotent stem cells: Insights into pluripotency and implications for disease
-
Rada-Iglesias A, Wysocka J (2011) Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease. Genome Med 3(6):36
-
(2011)
Genome Med
, vol.3
, Issue.6
, pp. 36
-
-
Rada-Iglesias, A.1
Wysocka, J.2
-
4
-
-
1842411320
-
Crystal structure of the nucleosome core particle at 2.8 a resolution
-
Luger K, Mader AW, Richmond RK, Sargent DF et al (1997) Crystal structure of the nucleosome core particle at 2.8 a resolution. Nature 389(6648):251-260
-
(1997)
Nature
, vol.389
, Issue.6648
, pp. 251-260
-
-
Luger, K.1
Mader, A.W.2
Richmond, R.K.3
Sargent, D.F.4
-
5
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD (2001) Translating the histone code. Science (New York, NY) 293(5532):1074-1080
-
(2001)
Science (New York, NY
, vol.293
, Issue.5532
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
6
-
-
78650758676
-
Histone H3K27ac separates active from poised enhancers and predicts developmental state
-
Creyghton MP, Cheng AW, Welstead GG, Kooistra T et al (2010) Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc Natl Acad Sci U S A 107(50):21931-21936
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.50
, pp. 21931-21936
-
-
Creyghton, M.P.1
Cheng, A.W.2
Welstead, G.G.3
Kooistra, T.4
-
7
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen TS, Ku M, Jaffe DB, Issac B et al (2007) Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448(7153):553-560
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
Issac, B.4
-
8
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein BE, Mikkelsen TS, Xie X, Kamal M et al (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125(2):315-326
-
(2006)
Cell
, vol.125
, Issue.2
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
-
9
-
-
58049191558
-
Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
-
Cui K, Zang C, Roh TY, Schones DE et al (2009) Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell 4(1):80-93
-
(2009)
Cell Stem Cell
, vol.4
, Issue.1
, pp. 80-93
-
-
Cui, K.1
Zang, C.2
Roh, T.Y.3
Schones, D.E.4
-
10
-
-
55449105221
-
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains
-
Ku M, Koche RP, Rheinbay E, Mendenhall EM et al (2008) Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet 4(10):e1000242
-
(2008)
PLoS Genet
, vol.4
, Issue.10
-
-
Ku, M.1
Koche, R.P.2
Rheinbay, E.3
Mendenhall, E.M.4
-
11
-
-
79955583542
-
Mapping and analysis of chromatin state dynamics in nine human cell types
-
Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N et al (2011) Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473(7345): 43-49
-
(2011)
Nature
, vol.473
, Issue.7345
, pp. 43-49
-
-
Ernst, J.1
Kheradpour, P.2
Mikkelsen, T.S.3
Shoresh, N.4
-
12
-
-
80052298366
-
Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage
-
Lien WH, Guo X, Polak L, Lawton LN et al (2011) Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage. Cell Stem Cell 9(3):219-232
-
(2011)
Cell Stem Cell
, vol.9
, Issue.3
, pp. 219-232
-
-
Lien, W.H.1
Guo, X.2
Polak, L.3
Lawton, L.N.4
-
13
-
-
77955172885
-
Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors
-
Adli M, Zhu J, Bernstein BE (2010) Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors. Nat Methods 7(8):615-618
-
(2010)
Nat Methods
, vol.7
, Issue.8
, pp. 615-618
-
-
Adli, M.1
Zhu, J.2
Bernstein, B.E.3
-
14
-
-
33646870495
-
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
-
Bracken AP, Dietrich N, Pasini D, Hansen KH et al (2006) Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 20(9):1123-1136
-
(2006)
Genes Dev
, vol.20
, Issue.9
, pp. 1123-1136
-
-
Bracken, A.P.1
Dietrich, N.2
Pasini, D.3
Hansen, K.H.4
-
15
-
-
51649129596
-
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
-
Mohn F, Weber M, Rebhan M, Roloff TC et al (2008) Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell 30(6):755-766
-
(2008)
Mol Cell
, vol.30
, Issue.6
, pp. 755-766
-
-
Mohn, F.1
Weber, M.2
Rebhan, M.3
Roloff, T.C.4
-
16
-
-
62249133709
-
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
-
Guttman M, Amit I, Garber M, French C et al (2009) Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 458(7235):223-227
-
(2009)
Nature
, vol.458
, Issue.7235
, pp. 223-227
-
-
Guttman, M.1
Amit, I.2
Garber, M.3
French, C.4
-
17
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA et al (2011) A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470(7333):279-283
-
(2011)
Nature
, vol.470
, Issue.7333
, pp. 279-283
-
-
Rada-Iglesias, A.1
Bajpai, R.2
Swigut, T.3
Brugmann, S.A.4
-
18
-
-
17944380227
-
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
-
Peters AH, O'Carroll D, Scherthan H, Mechtler K et al (2001) Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107(3):323-337
-
(2001)
Cell
, vol.107
, Issue.3
, pp. 323-337
-
-
Peters, A.H.1
O'Carroll, D.2
Scherthan, H.3
Mechtler, K.4
-
19
-
-
1542314243
-
Histone H3-K9 methyltransferase ESET is essential for early development
-
Dodge JE, Kang YK, Beppu H, Lei H et al (2004) Histone H3-K9 methyltransferase ESET is essential for early development. Mol Cell Biol 24(6):2478-2486
-
(2004)
Mol Cell Biol
, vol.24
, Issue.6
, pp. 2478-2486
-
-
Dodge, J.E.1
Kang, Y.K.2
Beppu, H.3
Lei, H.4
-
20
-
-
77149144362
-
ERGassociated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage
-
Yeap LS, Hayashi K, Surani MA (2009) ERGassociated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage. Epigenetics Chromatin 2(1):12
-
(2009)
Epigenetics Chromatin
, vol.2
, Issue.1
, pp. 12
-
-
Yeap, L.S.1
Hayashi, K.2
Surani, M.A.3
-
21
-
-
70350686165
-
Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
-
Yuan P, Han J, Guo G, Orlov YL et al (2009) Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells. Genes Dev 23(21):2507-2520
-
(2009)
Genes Dev
, vol.23
, Issue.21
, pp. 2507-2520
-
-
Yuan, P.1
Han, J.2
Guo, G.3
Orlov, Y.L.4
-
22
-
-
77950862656
-
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET
-
Matsui T, Leung D, Miyashita H, Maksakova IA et al (2010) Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature 464(7290):927-931
-
(2010)
Nature
, vol.464
, Issue.7290
, pp. 927-931
-
-
Matsui, T.1
Leung, D.2
Miyashita, H.3
Maksakova, I.A.4
-
23
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
Gu TP, Guo F, Yang H, Wu HP et al (2011) The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 477:606-610
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
Guo, F.2
Yang, H.3
Wu, H.P.4
-
24
-
-
80955179571
-
Stem cells and reprogramming: Breaking the epigenetic barrier?
-
Ang YS, Gaspar-Maia A, Lemischka IR, Bernstein E (2011) Stem cells and reprogramming: breaking the epigenetic barrier? Trends Pharmacol Sci 32(7):394-401
-
(2011)
Trends Pharmacol Sci
, vol.32
, Issue.7
, pp. 394-401
-
-
Ang, Y.S.1
Gaspar-Maia, A.2
Lemischka, I.R.3
Bernstein, E.4
-
25
-
-
79960530899
-
Genomic imprinting: The emergence of an epigenetic paradigm
-
Ferguson-Smith AC (2011) Genomic imprinting: the emergence of an epigenetic paradigm. Nat Rev 12(8):565-575
-
(2011)
Nat Rev
, vol.12
, Issue.8
, pp. 565-575
-
-
Ferguson-Smith, A.C.1
-
26
-
-
79956306617
-
Regulation of X-chromosome inactivation by the X-inactivation centre
-
Augui S, Nora EP, Heard E (2011) Regulation of X-chromosome inactivation by the X-inactivation centre. Nat Rev 12(6):429-442
-
(2011)
Nat Rev
, vol.12
, Issue.6
, pp. 429-442
-
-
Augui, S.1
Nora, E.P.2
Heard, E.3
-
27
-
-
34547881887
-
Xist function: Bridging chromatin and stem cells
-
Wutz A (2007) Xist function: bridging chromatin and stem cells. Trends Genet 23(9):457-464
-
(2007)
Trends Genet
, vol.23
, Issue.9
, pp. 457-464
-
-
Wutz, A.1
-
28
-
-
77950223473
-
Mechanisms of trophectoderm fate specification in preimplantation mouse development
-
Sasaki H (2010) Mechanisms of trophectoderm fate specification in preimplantation mouse development. Dev Growth Differ 52(3):263-273
-
(2010)
Dev Growth Differ
, vol.52
, Issue.3
, pp. 263-273
-
-
Sasaki, H.1
-
29
-
-
74349118193
-
Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx
-
Ralston A, Cox BJ, Nishioka N, Sasaki H et al (2010) Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx. Development (Cambridge, England) 137(3):395-403
-
(2010)
Development (Cambridge, England
, vol.137
, Issue.3
, pp. 395-403
-
-
Ralston, A.1
Cox, B.J.2
Nishioka, N.3
Sasaki, H.4
-
30
-
-
28344436489
-
Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation
-
Niwa H, Toyooka Y, Shimosato D, Strumpf D et al (2005) Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation. Cell 123(5):917-929
-
(2005)
Cell
, vol.123
, Issue.5
, pp. 917-929
-
-
Niwa, H.1
Toyooka, Y.2
Shimosato, D.3
Strumpf, D.4
-
31
-
-
76549104704
-
Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation
-
Li L, Sun L, Gao F, Jiang J et al (2010) Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation. Proc Natl Acad Sci U S A 107(4):1402-1407
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.4
, pp. 1402-1407
-
-
Li, L.1
Sun, L.2
Gao, F.3
Jiang, J.4
-
32
-
-
33646527782
-
Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway
-
Chazaud C, Yamanaka Y, Pawson T, Rossant J (2006) Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev Cell 10(5):615-624
-
(2006)
Dev Cell
, vol.10
, Issue.5
, pp. 615-624
-
-
Chazaud, C.1
Yamanaka, Y.2
Pawson, T.3
Rossant, J.4
-
33
-
-
70349934958
-
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
-
Nichols J, Silva J, Roode M, Smith A (2009) Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development (Cambridge, England) 136(19):3215-3222
-
(2009)
Development (Cambridge, England
, vol.136
, Issue.19
, pp. 3215-3222
-
-
Nichols, J.1
Silva, J.2
Roode, M.3
Smith, A.4
-
34
-
-
68749110887
-
Nanog is the gateway to the pluripotent ground state
-
Silva J, Nichols J, Theunissen TW, Guo G et al (2009) Nanog is the gateway to the pluripotent ground state. Cell 138(4):722-737
-
(2009)
Cell
, vol.138
, Issue.4
, pp. 722-737
-
-
Silva, J.1
Nichols, J.2
Theunissen, T.W.3
Guo, G.4
-
35
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
Mitsui K, Tokuzawa Y, Itoh H, Segawa K et al (2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113(5):631-642
-
(2003)
Cell
, vol.113
, Issue.5
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
-
36
-
-
37549002155
-
Nanog safeguards pluripotency and mediates germline development
-
Chambers I, Silva J, Colby D, Nichols J et al (2007) Nanog safeguards pluripotency and mediates germline development. Nature 450(7173):1230-1234
-
(2007)
Nature
, vol.450
, Issue.7173
, pp. 1230-1234
-
-
Chambers, I.1
Silva, J.2
Colby, D.3
Nichols, J.4
-
37
-
-
33845985573
-
Stem cells and lineage development in the mammalian blastocyst
-
Rossant J (2007) Stem cells and lineage development in the mammalian blastocyst. Reprod Fertil Dev 19(1):111-118
-
(2007)
Reprod Fertil Dev
, vol.19
, Issue.1
, pp. 111-118
-
-
Rossant, J.1
-
38
-
-
20244381688
-
Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts
-
Kunath T, Arnaud D, Uy GD, Okamoto I et al (2005) Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts. Development (Cambridge, England) 132(7):1649-1661
-
(2005)
Development (Cambridge, England
, vol.132
, Issue.7
, pp. 1649-1661
-
-
Kunath, T.1
Arnaud, D.2
Uy, G.D.3
Okamoto, I.4
-
39
-
-
33846156141
-
F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses
-
Poueymirou WT, Auerbach W, Frendewey D, Hickey JF et al (2007) F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses. Nat Biotechnol 25(1):91-99
-
(2007)
Nat Biotechnol
, vol.25
, Issue.1
, pp. 91-99
-
-
Poueymirou, W.T.1
Auerbach, W.2
Frendewey, D.3
Hickey, J.F.4
-
40
-
-
0025245614
-
Embryonic stem cells alone are able to support fetal development in the mouse
-
Nagy A, Gocza E, Diaz EM, Prideaux VR et al (1990) Embryonic stem cells alone are able to support fetal development in the mouse. Development (Cambridge, England) 110(3):815-821
-
(1990)
Development (Cambridge, England
, vol.110
, Issue.3
, pp. 815-821
-
-
Nagy, A.1
Gocza, E.2
Diaz, E.M.3
Prideaux, V.R.4
-
41
-
-
68049097008
-
Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddington's canal
-
Hemberger M, Dean W, Reik W (2009) Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal. Nat Rev Mol Cell Biol 10(8):526-537
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.8
, pp. 526-537
-
-
Hemberger, M.1
Dean, W.2
Reik, W.3
-
42
-
-
55549119925
-
Epigenetic restriction of embryonic cell lineage fate by methylation of Elf
-
Ng RK, Dean W, Dawson C, Lucifero D et al (2008) Epigenetic restriction of embryonic cell lineage fate by methylation of Elf. Nat Cell Biol 10(11):1280-1290
-
(2008)
Nat Cell Biol
, vol.10
, Issue.11
, pp. 1280-1290
-
-
Ng, R.K.1
Dean, W.2
Dawson, C.3
Lucifero, D.4
-
43
-
-
77955759070
-
Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment
-
Alder O, Lavial F, Helness A, Brookes E et al (2011) Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment. Development (Cambridge, England) 137(15):2483-2492
-
(2011)
Development (Cambridge, England)
, vol.137
, Issue.15
, pp. 2483-2492
-
-
Alder, O.1
Lavial, F.2
Helness, A.3
Brookes, E.4
-
44
-
-
34447527158
-
Derivation of pluripotent epiblast stem cells from mammalian embryos
-
Brons IG, Smithers LE, Trotter MW, Rugg-Gunn P et al (2007) Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448(7150):191-195
-
(2007)
Nature
, vol.448
, Issue.7150
, pp. 191-195
-
-
Brons, I.G.1
Smithers, L.E.2
Trotter, M.W.3
Rugg-Gunn, P.4
-
45
-
-
34447528757
-
New cell lines from mouse epiblast share Defining features with human embryonic stem cells
-
Tesar PJ, Chenoweth JG, Brook FA, Davies TJ et al (2007) New cell lines from mouse epiblast share Defining features with human embryonic stem cells. Nature 448(7150):196-199
-
(2007)
Nature
, vol.448
, Issue.7150
, pp. 196-199
-
-
Tesar, P.J.1
Chenoweth, J.G.2
Brook, F.A.3
Davies, T.J.4
-
46
-
-
79961149681
-
BRACHYURY and CDX2 mediate BMPinduced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages
-
Bernardo AS, Faial T, Gardner L, Niakan KK et al (2011) BRACHYURY and CDX2 mediate BMPinduced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages. Cell Stem Cell 9(2):144-155
-
(2011)
Cell Stem Cell
, vol.9
, Issue.2
, pp. 144-155
-
-
Bernardo, A.S.1
Faial, T.2
Gardner, L.3
Niakan, K.K.4
-
47
-
-
80052475509
-
Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
-
ten Berge D, Kurek D, Blauwkamp T, Koole W et al (2011) Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells. Nat Cell Biol 13(9):1070-1075
-
(2011)
Nat Cell Biol
, vol.13
, Issue.9
, pp. 1070-1075
-
-
Ten Berge, D.1
Kurek, D.2
Blauwkamp, T.3
Koole, W.4
-
48
-
-
66049136895
-
Klf4 reverts developmentally programmed restriction of ground state pluripotency
-
Guo G, Yang J, Nichols J, Hall JS et al (2009) Klf4 reverts developmentally programmed restriction of ground state pluripotency. Development (Cambridge, England) 136(7):1063-1069
-
(2009)
Development (Cambridge, England
, vol.136
, Issue.7
, pp. 1063-1069
-
-
Guo, G.1
Yang, J.2
Nichols, J.3
Hall, J.S.4
-
49
-
-
66049117813
-
Naive and primed pluripotent states
-
Nichols J, Smith A (2009) Naive and primed pluripotent states. Cell Stem Cell 4(6):487-492
-
(2009)
Cell Stem Cell
, vol.4
, Issue.6
, pp. 487-492
-
-
Nichols, J.1
Smith, A.2
-
50
-
-
77952699848
-
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs
-
Hanna J, Cheng AW, Saha K, Kim J et al (2010) Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs. Proc Natl Acad Sci U S A 107(20):9222-9227
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.20
, pp. 9222-9227
-
-
Hanna, J.1
Cheng, A.W.2
Saha, K.3
Kim, J.4
-
51
-
-
77952732489
-
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations
-
Lengner CJ, Gimelbrant AA, Erwin JA, Cheng AW et al (2010) Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell 141(5):872-883
-
(2010)
Cell
, vol.141
, Issue.5
, pp. 872-883
-
-
Lengner, C.J.1
Gimelbrant, A.A.2
Erwin, J.A.3
Cheng, A.W.4
-
52
-
-
78149500053
-
Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages
-
Han DW, Tapia N, Joo JY, Greber B et al (2010) Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages. Cell 143(4):617-627
-
(2010)
Cell
, vol.143
, Issue.4
, pp. 617-627
-
-
Han, D.W.1
Tapia, N.2
Joo, J.Y.3
Greber, B.4
-
53
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
Boyer LA, Plath K, Zeitlinger J, Brambrink T et al (2006) Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441(7091):349-353
-
(2006)
Nature
, vol.441
, Issue.7091
, pp. 349-353
-
-
Boyer, L.A.1
Plath, K.2
Zeitlinger, J.3
Brambrink, T.4
-
54
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A, Mikkelsen TS, Gu H, Wernig M et al (2008) Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454(7205):766-770
-
(2008)
Nature
, vol.454
, Issue.7205
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
Wernig, M.4
-
55
-
-
79955948324
-
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
-
Xu Y, Wu F, Tan L, Kong L et al (2011) Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol Cell 42(4):451-464
-
(2011)
Mol Cell
, vol.42
, Issue.4
, pp. 451-464
-
-
Xu, Y.1
Wu, F.2
Tan, L.3
Kong, L.4
-
56
-
-
78751590899
-
Silencing chromatin: Comparing modes and mechanisms
-
Beisel C, Paro R (2011) Silencing chromatin: comparing modes and mechanisms. Nat Rev 12(2):123-135
-
(2011)
Nat Rev
, vol.12
, Issue.2
, pp. 123-135
-
-
Beisel, C.1
Paro, R.2
-
57
-
-
77954676296
-
Origin of the polycomb repressive complex 2 and gene silencing by an E(z) homolog in the unicellular alga Chlamydomonas
-
Shaver S, Casas-Mollano JA, Cerny RL, Cerutti H (2010) Origin of the polycomb repressive complex 2 and gene silencing by an E(z) homolog in the unicellular alga Chlamydomonas. Epigenetics 5(4):301-312
-
(2010)
Epigenetics
, vol.5
, Issue.4
, pp. 301-312
-
-
Shaver, S.1
Casas-Mollano, J.A.2
Cerny, R.L.3
Cerutti, H.4
-
58
-
-
7744228427
-
Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation
-
de Napoles M, Mermoud JE, Wakao R, Tang YA et al (2004) Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev Cell 7(5):663-676
-
(2004)
Dev Cell
, vol.7
, Issue.5
, pp. 663-676
-
-
De Napoles, M.1
Mermoud, J.E.2
Wakao, R.3
Tang, Y.A.4
-
59
-
-
11144237618
-
Ring1bmediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation
-
Fang J, Chen T, Chadwick B, Li E et al (2004) Ring1bmediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation. J Biol Chem 279(51):52812-52815
-
(2004)
J Biol Chem
, vol.279
, Issue.51
, pp. 52812-52815
-
-
Fang, J.1
Chen, T.2
Chadwick, B.3
Li, E.4
-
60
-
-
0036830642
-
Role of histone H3 lysine 27 methylation in Polycomb-group silencing
-
Cao R, Wang L, Wang H, Xia L et al (2002) Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science (New York, NY) 298(5595): 1039-1043
-
(2002)
Science (New York, NY
, vol.298
, Issue.5595
, pp. 1039-1043
-
-
Cao, R.1
Wang, L.2
Wang, H.3
Xia, L.4
-
61
-
-
36749089980
-
Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells
-
Stock JK, Giadrossi S, Casanova M, Brookes E et al (2007) Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells. Nat Cell Biol 9(12):1428-1435
-
(2007)
Nat Cell Biol
, vol.9
, Issue.12
, pp. 1428-1435
-
-
Stock, J.K.1
Giadrossi, S.2
Casanova, M.3
Et Al., B.E.4
-
62
-
-
33847084602
-
Genome regulation by polycomb and trithorax proteins
-
Schuettengruber B, Chourrout D, Vervoort M, Leblanc B et al (2007) Genome regulation by polycomb and trithorax proteins. Cell 128(4):735-745
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 735-745
-
-
Schuettengruber, B.1
Chourrout, D.2
Vervoort, M.3
Leblanc, B.4
-
63
-
-
77956919550
-
Polycomb group protein displacement and gene activation through MSKdependent H3K27me3S28 phosphorylation
-
Gehani SS, Agrawal-Singh S, Dietrich N, Christophersen NS et al (2010) Polycomb group protein displacement and gene activation through MSKdependent H3K27me3S28 phosphorylation. Mol Cell 39(6):886-900
-
(2010)
Mol Cell
, vol.39
, Issue.6
, pp. 886-900
-
-
Gehani, S.S.1
Agrawal-Singh, S.2
Dietrich, N.3
Christophersen, N.S.4
-
64
-
-
77951428293
-
UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis
-
Seenundun S, Rampalli S, Liu QC, Aziz A et al (2010) UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis. EMBO J 29(8):1401-1411
-
(2010)
EMBO J
, vol.29
, Issue.8
, pp. 1401-1411
-
-
Seenundun, S.1
Rampalli, S.2
Liu, Q.C.3
Aziz, A.4
-
65
-
-
77952429798
-
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
-
Scheuermann JC, de Ayala Alonso AG, Oktaba K, Ly-Hartig N et al (2010) Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB. Nature 465(7295):243-247
-
(2010)
Nature
, vol.465
, Issue.7295
, pp. 243-247
-
-
Scheuermann, J.C.1
De Ayala Alonso, A.G.2
Oktaba, K.3
Ly-Hartig, N.4
-
66
-
-
78650816023
-
Transcriptional activation of polycomb-repressed genes by ZRF
-
Richly H, Rocha-Viegas L, Ribeiro JD, Demajo S et al (2010) Transcriptional activation of polycomb-repressed genes by ZRF. Nature 468(7327):1124-1128
-
(2010)
Nature
, vol.468
, Issue.7327
, pp. 1124-1128
-
-
Richly, H.1
Rocha-Viegas, L.2
Ribeiro, J.D.3
Demajo, S.4
-
67
-
-
42649100978
-
SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation
-
Blewitt ME, Gendrel AV, Pang Z, Sparrow DB et al (2008) SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation. Nat Genet 40(5):663-669
-
(2008)
Nat Genet
, vol.40
, Issue.5
, pp. 663-669
-
-
Blewitt, M.E.1
Gendrel, A.V.2
Pang, Z.3
Sparrow, D.B.4
-
68
-
-
0034665756
-
X inactivation in the mouse embryo deficient for Dnmt1: Distinct effect of hypomethylation on imprinted and random X inactivation
-
Sado T, Fenner MH, Tan SS, Tam P et al (2000) X inactivation in the mouse embryo deficient for Dnmt1: distinct effect of hypomethylation on imprinted and random X inactivation. Dev Biol 225(2):294-303
-
(2000)
Dev Biol
, vol.225
, Issue.2
, pp. 294-303
-
-
Sado, T.1
Fenner, M.H.2
Tan, S.S.3
Tam, P.4
-
69
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, Pastor WA et al (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (New York, NY) 324(5929):930-935
-
(2009)
Science (New York, NY
, vol.324
, Issue.5929
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
-
70
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams K, Christensen J, Pedersen MT, Johansen JV et al (2011) TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473(7347):343-348
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 343-348
-
-
Williams, K.1
Christensen, J.2
Pedersen, M.T.3
Johansen, J.V.4
-
71
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor WA, Pape UJ, Huang Y, Henderson HR et al (2011) Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 473(7347):394-397
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
Henderson, H.R.4
-
72
-
-
79956292024
-
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
-
Wu H, D'Alessio AC, Ito S, Xia K et al (2011) Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 473(7347):389-393
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 389-393
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Xia, K.4
-
73
-
-
34250729138
-
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
-
Rinn JL, Kertesz M, Wang JK, Squazzo SL et al (2007) Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 129(7):1311-1323
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1311-1323
-
-
Rinn, J.L.1
Kertesz, M.2
Wang, J.K.3
Squazzo, S.L.4
-
74
-
-
19344375746
-
A chromosomal memory triggered by Xist regulates histone methylation in X inactivation
-
Kohlmaier A, Savarese F, Lachner M, Martens J et al (2004) A chromosomal memory triggered by Xist regulates histone methylation in X inactivation. PLoS Biol 2(7):E171
-
(2004)
PLoS Biol
, vol.2
, Issue.7
-
-
Kohlmaier, A.1
Savarese, F.2
Lachner, M.3
Martens, J.4
-
75
-
-
0037172659
-
Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells
-
Mak W, Baxter J, Silva J, Newall AE et al (2002) Mitotically stable association of polycomb group proteins eed and enx1 with the inactive x chromosome in trophoblast stem cells. Curr Biol 12(12):1016-1020
-
(2002)
Curr Biol
, vol.12
, Issue.12
, pp. 1016-1020
-
-
Mak, W.1
Baxter, J.2
Silva, J.3
Newall, A.E.4
-
76
-
-
0242668706
-
Role of histone H3 lysine 27 methylation in X inactivation
-
Plath K, Fang J, Mlynarczyk-Evans SK, Cao R et al (2003) Role of histone H3 lysine 27 methylation in X inactivation. Science (New York, NY) 300(5616):131-135
-
(2003)
Science (New York, NY
, vol.300
, Issue.5616
, pp. 131-135
-
-
Plath, K.1
Fang, J.2
Mlynarczyk-Evans, S.K.3
Cao, R.4
-
77
-
-
67650921949
-
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
-
Khalil AM, Guttman M, Huarte M, Garber M et al (2009) Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl Acad Sci U S A 106(28):11667-11672
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.28
, pp. 11667-11672
-
-
Khalil, A.M.1
Guttman, M.2
Huarte, M.3
Garber, M.4
-
78
-
-
80052869283
-
LincRNAs act in the circuitry controlling pluripotency and differentiation
-
Guttman M, Donaghey J, Carey BW, Garber M et al (2011) lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature 477(7364):295-300
-
(2011)
Nature
, vol.477
, Issue.7364
, pp. 295-300
-
-
Guttman, M.1
Donaghey, J.2
Carey, B.W.3
Garber, M.4
-
79
-
-
33749177531
-
Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation
-
Savarese F, Flahndorfer K, Jaenisch R, Busslinger M et al (2006) Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation. Mol Cell Biol 26(19):7167-7177
-
(2006)
Mol Cell Biol
, vol.26
, Issue.19
, pp. 7167-7177
-
-
Savarese, F.1
Flahndorfer, K.2
Jaenisch, R.3
Busslinger, M.4
-
80
-
-
64549153094
-
SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells
-
Agrelo R, Souabni A, Novatchkova M, Haslinger C et al (2009) SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells. Dev Cell 16(4):507-516
-
(2009)
Dev Cell
, vol.16
, Issue.4
, pp. 507-516
-
-
Agrelo, R.1
Souabni, A.2
Novatchkova, M.3
Haslinger, C.4
-
81
-
-
33750465872
-
SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes
-
Cai S, Lee CC, Kohwi-Shigematsu T (2006) SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. Nat Genet 38(11):1278-1288
-
(2006)
Nat Genet
, vol.38
, Issue.11
, pp. 1278-1288
-
-
Cai, S.1
Lee, C.C.2
Kohwi-Shigematsu, T.3
-
82
-
-
0034161939
-
The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development
-
Alvarez JD, Yasui DH, Niida H, Joh T et al (2000) The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development. Genes Dev 14(5):521-535
-
(2000)
Genes Dev
, vol.14
, Issue.5
, pp. 521-535
-
-
Alvarez, J.D.1
Yasui, D.H.2
Niida, H.3
Joh, T.4
-
83
-
-
77953679543
-
ConteXt of change-X inactivation and disease
-
Agrelo R, Wutz A (2010) ConteXt of change-X inactivation and disease. EMBO Mol Med 2(1):6-15
-
(2010)
EMBO Mol Med
, vol.2
, Issue.1
, pp. 6-15
-
-
Agrelo, R.1
Wutz, A.2
-
84
-
-
79956326274
-
Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas
-
Xu CR, Cole PA, Meyers DJ, Kormish J et al (2011) Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas. Science (New York, NY) 332(6032):963-966
-
(2011)
Science (New York, NY)
, vol.332
, Issue.6032
, pp. 963-966
-
-
Xu, C.R.1
Cole, P.A.2
Meyers, D.J.3
Kormish, J.4
-
85
-
-
77952966500
-
Derepression of Polycomb targets during pancreatic organogenesis allows insulinproducing beta-cells to adopt a neural gene activity program
-
van Arensbergen J, Garcia-Hurtado J, Moran I, Maestro MA et al (2011) Derepression of Polycomb targets during pancreatic organogenesis allows insulinproducing beta-cells to adopt a neural gene activity program. Genome Res 20(6):722-732
-
(2011)
Genome Res
, vol.20
, Issue.6
, pp. 722-732
-
-
Van Arensbergen, J.1
Garcia-Hurtado, J.2
Moran, I.3
Maestro, M.A.4
-
86
-
-
79959349283
-
Genome-wide remodeling of the epigenetic landscape during myogenic differentiation
-
Asp P, Blum R, Vethantham V, Parisi F et al (2011) Genome-wide remodeling of the epigenetic landscape during myogenic differentiation. Proc Natl Acad Sci U S A 108(22):E149-E158
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.22
-
-
Asp, P.1
Blum, R.2
Vethantham, V.3
Parisi, F.4
-
87
-
-
64849086360
-
SATB1: The convergence of carcinogenesis and chromatin conformation
-
Mai JC, Ellenbogen RG (2008) SATB1: the convergence of carcinogenesis and chromatin conformation. Neurosurgery 63(2):N6
-
(2008)
Neurosurgery
, vol.63
, Issue.2
-
-
Mai, J.C.1
Ellenbogen, R.G.2
-
88
-
-
44949163006
-
A new path to the cancer epigenome
-
Richon VM (2008) A new path to the cancer epigenome. Nat Biotechnol 26(6):655-656
-
(2008)
Nat Biotechnol
, vol.26
, Issue.6
, pp. 655-656
-
-
Richon, V.M.1
-
89
-
-
64549147462
-
SAT in silence
-
Brockdorff N (2009) SAT in silence. Dev Cell 16(4):483-484
-
(2009)
Dev Cell
, vol.16
, Issue.4
, pp. 483-484
-
-
Brockdorff, N.1
-
90
-
-
74549136925
-
Cancer progenitors and epigenetic contexts: An Xisting connection
-
Agrelo R, Wutz A (2009) Cancer progenitors and epigenetic contexts: an Xisting connection. Epigenetics 4(8):568-570
-
(2009)
Epigenetics
, vol.4
, Issue.8
, pp. 568-570
-
-
Agrelo, R.1
Wutz, A.2
-
91
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69(6):915-926
-
(1992)
Cell
, vol.69
, Issue.6
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
92
-
-
0035937404
-
Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene
-
Howell CY, Bestor TH, Ding F, Latham KE et al (2001) Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene. Cell 104(6):829-838
-
(2001)
Cell
, vol.104
, Issue.6
, pp. 829-838
-
-
Howell, C.Y.1
Bestor, T.H.2
Ding, F.3
Latham, K.E.4
-
93
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99(3):247-257
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
94
-
-
0035930660
-
Dnmt3L and the establishment of maternal genomic imprints
-
Bourc'his D, Xu GL, Lin CS, Bollman B et al (2001) Dnmt3L and the establishment of maternal genomic imprints. Science (New York, NY) 294(5551): 2536-2539
-
(2001)
Science (New York, NY
, vol.294
, Issue.5551
, pp. 2536-2539
-
-
Bourc'His, D.1
Xu, G.L.2
Lin, C.S.3
Bollman, B.4
-
95
-
-
36849072573
-
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
-
Sharif J, Muto M, Takebayashi S, Suetake I et al (2007) The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 450(7171):908-912
-
(2007)
Nature
, vol.450
, Issue.7171
, pp. 908-912
-
-
Sharif, J.1
Muto, M.2
Takebayashi, S.3
Suetake, I.4
-
96
-
-
77957824513
-
DNA methylation is dispensable for the growth and survival of the extraembryonic lineages
-
Sakaue M, Ohta H, Kumaki Y, Oda M et al (2010) DNA methylation is dispensable for the growth and survival of the extraembryonic lineages. Curr Biol 20(16):1452-1457
-
(2010)
Curr Biol
, vol.20
, Issue.16
, pp. 1452-1457
-
-
Sakaue, M.1
Ohta, H.2
Kumaki, Y.3
Oda, M.4
-
97
-
-
79961139741
-
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development
-
Dawlaty MM, Ganz K, Powell BE, Hu YC et al (2011) Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell 9(2):166-175
-
(2011)
Cell Stem Cell
, vol.9
, Issue.2
, pp. 166-175
-
-
Dawlaty, M.M.1
Ganz, K.2
Powell, B.E.3
Hu, Y.C.4
-
98
-
-
80052284526
-
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
-
Ko M, Bandukwala HS, An J, Lamperti ED et al (2011) Ten-Eleven- Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proc Natl Acad Sci U S A 108(35):14566-14571
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.35
, pp. 14566-14571
-
-
Ko, M.1
Bandukwala, H.S.2
An, J.3
Lamperti, E.D.4
-
99
-
-
80052285127
-
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
-
Li Z, Cai X, Cai CL, Wang J et al (2011) Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies. Blood 118(17):4509-4518
-
(2011)
Blood
, vol.118
, Issue.17
, pp. 4509-4518
-
-
Li, Z.1
Cai, X.2
Cai, C.L.3
Wang, J.4
-
100
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O et al (2011) Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 20(1):11-24
-
(2011)
Cancer Cell
, vol.20
, Issue.1
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
Abdel-Wahab, O.4
-
101
-
-
79960062301
-
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
-
Quivoron C, Couronne L, Della Valle V, Lopez CK et al (2011) TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 20(1):25-38
-
(2011)
Cancer Cell
, vol.20
, Issue.1
, pp. 25-38
-
-
Quivoron, C.1
Couronne, L.2
Della Valle, V.3
Lopez, C.K.4
-
102
-
-
79951810964
-
Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability
-
Cortazar D, Kunz C, Selfridge J, Lettieri T et al (2011) Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability. Nature 470(7334):419-423
-
(2011)
Nature
, vol.470
, Issue.7334
, pp. 419-423
-
-
Cortazar, D.1
Kunz, C.2
Selfridge, J.3
Lettieri, T.4
-
103
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino S, Xu J, Sannai M, Moore R et al (2011) Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 146(1):67-79
-
(2011)
Cell
, vol.146
, Issue.1
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
Moore, R.4
-
104
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He YF, Li BZ, Li Z, Liu P et al (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science (New York, NY) 333(6047):1303-1307
-
(2011)
Science (New York, NY)
, vol.333
, Issue.6047
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
-
105
-
-
0034977239
-
The polycomb-group gene Ezh2 is required for early mouse development
-
O'Carroll D, Erhardt S, Pagani M, Barton SC et al (2001) The polycomb-group gene Ezh2 is required for early mouse development. Mol Cell Biol 21(13): 4330-4336
-
(2001)
Mol Cell Biol
, vol.21
, Issue.13
, pp. 4330-4336
-
-
O'Carroll, D.1
Erhardt, S.2
Pagani, M.3
Barton, S.C.4
-
106
-
-
8144230178
-
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
-
Pasini D, Bracken AP, Jensen MR, Lazzerini Denchi E et al (2004) Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J 23(20):4061-4071
-
(2004)
EMBO J
, vol.23
, Issue.20
, pp. 4061-4071
-
-
Pasini, D.1
Bracken, A.P.2
Jensen, M.R.3
Lazzerini Denchi, E.4
-
107
-
-
0030593898
-
Positional cloning of a global regulator of anteriorposterior patterning in mice
-
Schumacher A, Faust C, Magnuson T (1996) Positional cloning of a global regulator of anteriorposterior patterning in mice. Nature 384(6610):648
-
(1996)
Nature
, vol.384
, Issue.6610
, pp. 648
-
-
Schumacher, A.1
Faust, C.2
Magnuson, T.3
-
108
-
-
0345269795
-
Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition
-
Voncken JW, Roelen BA, Roefs M, de Vries S et al (2003) Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition. Proc Natl Acad Sci U S A 100(5):2468-2473
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.5
, pp. 2468-2473
-
-
Voncken, J.W.1
Roelen, B.A.2
Roefs, M.3
De Vries, S.4
-
109
-
-
0037099413
-
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis
-
Tachibana M, Sugimoto K, Nozaki M, Ueda J et al (2002) G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev 16(14):1779-1791
-
(2002)
Genes Dev
, vol.16
, Issue.14
, pp. 1779-1791
-
-
Tachibana, M.1
Sugimoto, K.2
Nozaki, M.3
Ueda, J.4
-
110
-
-
54349095323
-
G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription
-
Tachibana M, Matsumura Y, Fukuda M, Kimura H et al (2008) G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription. EMBO J 27(20):2681-2690
-
(2008)
EMBO J
, vol.27
, Issue.20
, pp. 2681-2690
-
-
Tachibana, M.1
Matsumura, Y.2
Fukuda, M.3
Kimura, H.4
-
111
-
-
0034934749
-
Imprinted X inactivation maintained by a mouse Polycomb group gene
-
Wang J, Mager J, Chen Y, Schneider E et al (2001) Imprinted X inactivation maintained by a mouse Polycomb group gene. Nat Genet 28(4):371-375
-
(2001)
Nat Genet
, vol.28
, Issue.4
, pp. 371-375
-
-
Wang, J.1
Mager, J.2
Chen, Y.3
Schneider, E.4
-
112
-
-
48649091905
-
Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency
-
Chamberlain SJ, Yee D, Magnuson T (2008) Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency. Stem Cells (Dayton, OH) 26(6):1496-1505
-
(2008)
Stem Cells (Dayton, OH
, vol.26
, Issue.6
, pp. 1496-1505
-
-
Chamberlain, S.J.1
Yee, D.2
Magnuson, T.3
-
113
-
-
34447508437
-
Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells
-
Leeb M, Wutz A (2007) Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells. J Cell Biol 178(2):219-229
-
(2007)
J Cell Biol
, vol.178
, Issue.2
, pp. 219-229
-
-
Leeb, M.1
Wutz, A.2
-
114
-
-
33746407708
-
Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
-
Schoeftner S, Sengupta AK, Kubicek S, Mechtler K et al (2006) Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing. EMBO J 25(13):3110-3122
-
(2006)
EMBO J
, vol.25
, Issue.13
, pp. 3110-3122
-
-
Schoeftner, S.1
Sengupta, A.K.2
Kubicek, S.3
Mechtler, K.4
-
115
-
-
76149142791
-
Polycomb complexes act redundantly to repress genomic repeats and genes
-
Leeb M, Pasini D, Novatchkova M, Jaritz M et al (2010) Polycomb complexes act redundantly to repress genomic repeats and genes. Genes Dev 24(3):265-276
-
(2010)
Genes Dev
, vol.24
, Issue.3
, pp. 265-276
-
-
Leeb, M.1
Pasini, D.2
Novatchkova, M.3
Jaritz, M.4
-
116
-
-
55949124844
-
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency
-
Shen X, Liu Y, Hsu YJ, Fujiwara Y et al (2008) EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol Cell 32(4):491-502
-
(2008)
Mol Cell
, vol.32
, Issue.4
, pp. 491-502
-
-
Shen, X.1
Liu, Y.2
Hsu, Y.J.3
Fujiwara, Y.4
-
117
-
-
79952220410
-
EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
-
Ezhkova E, Lien WH, Stokes N, Pasolli HA et al (2011) EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev 25(5):485-498
-
(2011)
Genes Dev
, vol.25
, Issue.5
, pp. 485-498
-
-
Ezhkova, E.1
Lien, W.H.2
Stokes, N.3
Pasolli, H.A.4
-
118
-
-
77951871731
-
The JARID2-PRC2 duality
-
Herz HM, Shilatifard A (2010) The JARID2-PRC2 duality. Genes Dev 24(9):857-861
-
(2010)
Genes Dev
, vol.24
, Issue.9
, pp. 857-861
-
-
Herz, H.M.1
Shilatifard, A.2
-
119
-
-
76749083433
-
Jarid2 and PRC2, partners in regulating gene expression
-
Li G, Margueron R, Ku M, Chambon P et al (2010) Jarid2 and PRC2, partners in regulating gene expression. Genes Dev 24(4):368-380
-
(2010)
Genes Dev
, vol.24
, Issue.4
, pp. 368-380
-
-
Li, G.1
Margueron, R.2
Ku, M.3
Chambon, P.4
-
120
-
-
77953120646
-
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators
-
Landeira D, Sauer S, Poot R, Dvorkina M et al (2010) Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators. Nat Cell Biol 12(6):618-624
-
(2010)
Nat Cell Biol
, vol.12
, Issue.6
, pp. 618-624
-
-
Landeira, D.1
Sauer, S.2
Poot, R.3
Dvorkina, M.4
-
121
-
-
77949414371
-
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells
-
Pasini D, Cloos PA, Walfridsson J, Olsson L et al (2010) JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells. Nature 464(7286):306-310
-
(2010)
Nature
, vol.464
, Issue.7286
, pp. 306-310
-
-
Pasini, D.1
Cloos, P.A.2
Walfridsson, J.3
Olsson, L.4
-
122
-
-
72249119297
-
Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells
-
Peng JC, Valouev A, Swigut T, Zhang J et al (2009) Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell 139(7):1290-1302
-
(2009)
Cell
, vol.139
, Issue.7
, pp. 1290-1302
-
-
Peng, J.C.1
Valouev, A.2
Swigut, T.3
Zhang, J.4
-
123
-
-
72249104107
-
Jumonji modulates polycomb activity and selfrenewal versus differentiation of stem cells
-
Shen X, Kim W, Fujiwara Y, Simon MD et al (2009) Jumonji modulates polycomb activity and selfrenewal versus differentiation of stem cells. Cell 139(7):1303-1314
-
(2009)
Cell
, vol.139
, Issue.7
, pp. 1303-1314
-
-
Shen, X.1
Kim, W.2
Fujiwara, Y.3
Simon, M.D.4
-
124
-
-
78751537712
-
Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes
-
Li X, Isono K, Yamada D, Endo TA et al (2010) Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes. Mol Cell Biol 31(2):351-364
-
(2010)
Mol Cell Biol
, vol.31
, Issue.2
, pp. 351-364
-
-
Li, X.1
Isono, K.2
Yamada, D.3
Endo, T.A.4
-
125
-
-
79955441928
-
Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells
-
Casanova M, Preissner T, Cerase A, Poot R et al (2011) Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells. Development (Cambridge, England) 138(8):1471-1482
-
(2011)
Development (Cambridge, England)
, vol.138
, Issue.8
, pp. 1471-1482
-
-
Casanova, M.1
Preissner, T.2
Cerase, A.3
Poot, R.4
-
126
-
-
77951947926
-
Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination
-
Eskeland R, Leeb M, Grimes GR, Kress C et al (2010) Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell 38(3):452-464
-
(2010)
Mol Cell
, vol.38
, Issue.3
, pp. 452-464
-
-
Eskeland, R.1
Leeb, M.2
Grimes, G.R.3
Kress, C.4
-
127
-
-
22344449361
-
Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
-
Molofsky AV, He S, Bydon M, Morrison SJ et al (2005) Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev 19(12):1432-1437
-
(2005)
Genes Dev
, vol.19
, Issue.12
, pp. 1432-1437
-
-
Molofsky, A.V.1
He, S.2
Bydon, M.3
Morrison, S.J.4
-
128
-
-
43249127096
-
Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity
-
Majewski IJ, Blewitt ME, de Graaf CA, McManus EJ et al (2008) Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity. PLoS Biol 6(4):e93
-
(2008)
PLoS Biol
, vol.6
, Issue.4
-
-
Majewski, I.J.1
Blewitt, M.E.2
De Graaf, C.A.3
McManus, E.J.4
-
129
-
-
10344258563
-
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1
-
Iwama A, Oguro H, Negishi M, Kato Y et al (2004) Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity 21(6):843-851
-
(2004)
Immunity
, vol.21
, Issue.6
, pp. 843-851
-
-
Iwama, A.1
Oguro, H.2
Negishi, M.3
Kato, Y.4
-
130
-
-
80054041585
-
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
-
Tian H, Biehs B, Warming S, Leong KG et al (2011) A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature 478(7368): 255-259
-
(2011)
Nature
, vol.478
, Issue.7368
, pp. 255-259
-
-
Tian, H.1
Biehs, B.2
Warming, S.3
Leong, K.G.4
-
131
-
-
80052261506
-
Jarid2 regulates mouse epidermal stem cell activation and differentiation
-
Mejetta S, Morey L, Pascual G, Kuebler B et al (2011) Jarid2 regulates mouse epidermal stem cell activation and differentiation. EMBO J 30(17):3635-3646
-
(2011)
EMBO J
, vol.30
, Issue.17
, pp. 3635-3646
-
-
Mejetta, S.1
Morey, L.2
Pascual, G.3
Kuebler, B.4
-
132
-
-
80052300618
-
Regulation of human epidermal stem cell proliferation and senescence requires polycomb-dependent and -independent functions of Cbx
-
Luis NM, Morey L, Mejetta S, Pascual G et al (2011) Regulation of human epidermal stem cell proliferation and senescence requires polycomb-dependent and -independent functions of Cbx. Cell Stem Cell 9(3):233-246
-
(2011)
Cell Stem Cell
, vol.9
, Issue.3
, pp. 233-246
-
-
Luis, N.M.1
Morey, L.2
Mejetta, S.3
Pascual, G.4
-
133
-
-
79955459714
-
Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells
-
Juan AH, Derfoul A, Feng X, Ryall JG et al (2011) Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells. Genes Dev 25(8):789-794
-
(2011)
Genes Dev
, vol.25
, Issue.8
, pp. 789-794
-
-
Juan, A.H.1
Derfoul, A.2
Feng, X.3
Ryall, J.G.4
-
134
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16(1):6-21
-
(2002)
Genes Dev
, vol.16
, Issue.1
, pp. 6-21
-
-
Bird, A.1
-
135
-
-
33745270104
-
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1
-
Tsumura A, Hayakawa T, Kumaki Y, Takebayashi S et al (2006) Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells 11(7):805-814
-
(2006)
Dnmt3a and Dnmt3b. Genes Cells
, vol.11
, Issue.7
, pp. 805-814
-
-
Tsumura, A.1
Hayakawa, T.2
Kumaki, Y.3
Takebayashi, S.4
-
136
-
-
34648833002
-
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
-
Bostick M, Kim JK, Esteve PO, Clark A et al (2007) UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science (New York, NY) 317(5845):1760-1764
-
(2007)
Science (New York, NY
, vol.317
, Issue.5845
, pp. 1760-1764
-
-
Bostick, M.1
Kim, J.K.2
Esteve, P.O.3
Clark, A.4
-
137
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz G, Branco MR, Seisenberger S, Santos F et al (2011) Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473(7347):398-402
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
Santos, F.4
-
138
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito S, D'Alessio AC, Taranova OV, Hong K et al (2010) Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466(7310):1129-1133
-
(2010)
Nature
, vol.466
, Issue.7310
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
-
139
-
-
79952763586
-
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
-
Iqbal K, Jin SG, Pfeifer GP, Szabo PE (2011) Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc Natl Acad Sci U S A 108(9):3642-3647
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.9
, pp. 3642-3647
-
-
Iqbal, K.1
Jin, S.G.2
Pfeifer, G.P.3
Szabo, P.E.4
-
140
-
-
80052476744
-
Molecular biology. Demystifying DNA demethylation
-
Nabel CS, Kohli RM (2011) Molecular biology. Demystifying DNA demethylation. Science (New York, NY) 333(6047):1229-1230
-
(2011)
Science (New York, NY)
, vol.333
, Issue.6047
, pp. 1229-1230
-
-
Nabel, C.S.1
Kohli, R.M.2
-
142
-
-
77149138834
-
KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation
-
Lohmann F, Loureiro J, Su H, Fang Q et al (2010) KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation. Stem Cells (Dayton, OH) 28(2):201-212
-
(2010)
Stem Cells (Dayton, OH)
, vol.28
, Issue.2
, pp. 201-212
-
-
Lohmann, F.1
Loureiro, J.2
Su, H.3
Fang, Q.4
-
143
-
-
34247333474
-
Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells
-
Kaji K, Nichols J, Hendrich B (2007) Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development (Cambridge, England) 134(6):1123-1132
-
(2007)
Development (Cambridge, England
, vol.134
, Issue.6
, pp. 1123-1132
-
-
Kaji, K.1
Nichols, J.2
Hendrich, B.3
-
144
-
-
33644764030
-
The NuRD component Mbd3 is required for pluripotency of embryonic stem cells
-
Kaji K, Caballero IM, MacLeod R, Nichols J et al (2006) The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nat Cell Biol 8(3):285-292
-
(2006)
Nat Cell Biol
, vol.8
, Issue.3
, pp. 285-292
-
-
Kaji, K.1
Caballero, I.M.2
Macleod, R.3
Nichols, J.4
-
145
-
-
0042310137
-
Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development
-
Erhardt S, Su IH, Schneider R, Barton S et al (2003) Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development (Cambridge, England) 130(18):4235-4248
-
(2003)
Development (Cambridge, England
, vol.130
, Issue.18
, pp. 4235-4248
-
-
Erhardt, S.1
Su, I.H.2
Schneider, R.3
Barton, S.4
-
146
-
-
79960926264
-
Dynamic CpG island methylation landscape in oocytes and preimplantation embryos
-
Smallwood SA, Tomizawa S, Krueger F, Ruf N et al (2011) Dynamic CpG island methylation landscape in oocytes and preimplantation embryos. Nat Genet 43(8):811-814
-
(2011)
Nat Genet
, vol.43
, Issue.8
, pp. 811-814
-
-
Smallwood, S.A.1
Tomizawa, S.2
Krueger, F.3
Ruf, N.4
-
147
-
-
58149506281
-
Transcription is required for establishment of germline methylation marks at imprinted genes
-
Chotalia M, Smallwood SA, Ruf N, Dawson C et al (2009) Transcription is required for establishment of germline methylation marks at imprinted genes. Genes Dev 23(1):105-117
-
(2009)
Genes Dev
, vol.23
, Issue.1
, pp. 105-117
-
-
Chotalia, M.1
Smallwood, S.A.2
Ruf, N.3
Dawson, C.4
-
148
-
-
70349272130
-
KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints
-
Ciccone DN, Su H, Hevi S, Gay F et al (2009) KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature 461(7262):415-418
-
(2009)
Nature
, vol.461
, Issue.7262
, pp. 415-418
-
-
Ciccone, D.N.1
Su, H.2
Hevi, S.3
Gay, F.4
-
149
-
-
33846783261
-
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase
-
Kubicek S, O'Sullivan RJ, August EM, Hickey ER et al (2007) Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol Cell 25(3):473-481
-
(2007)
Mol Cell
, vol.25
, Issue.3
, pp. 473-481
-
-
Kubicek, S.1
O'Sullivan, R.J.2
August, E.M.3
Hickey, E.R.4
-
150
-
-
78650968882
-
Stable transmission of reversible modifications: Maintenance of epigenetic information through the cell cycle
-
Blomen VA, Boonstra J (2011) Stable transmission of reversible modifications: maintenance of epigenetic information through the cell cycle. Cell Mol Life Sci 68(1):27-44
-
(2011)
Cell Mol Life Sci
, vol.68
, Issue.1
, pp. 27-44
-
-
Blomen, V.A.1
Boonstra, J.2
-
151
-
-
33750501629
-
The Polycomb-associated protein Rybp is a ubiquitin binding protein
-
Arrigoni R, Alam SL, Wamstad JA, Bardwell VJ et al (2006) The Polycomb-associated protein Rybp is a ubiquitin binding protein. FEBS Lett 580(26): 6233-6241
-
(2006)
FEBS Lett
, vol.580
, Issue.26
, pp. 6233-6241
-
-
Arrigoni, R.1
Alam, S.L.2
Wamstad, J.A.3
Bardwell, V.J.4
-
152
-
-
0344223442
-
RYBP a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY
-
Garcia E, Marcos-Gutierrez C, del Mar LM, Moreno JC et al (1999) RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY. EMBO J 18(12):3404-3418
-
(1999)
EMBO J
, vol.18
, Issue.12
, pp. 3404-3418
-
-
Garcia, E.1
Marcos-Gutierrez, C.2
Del Mar, L.M.3
Moreno, J.C.4
-
153
-
-
55549103314
-
A model for transmission of the H3K27me3 epigenetic mark
-
Hansen KH, Bracken AP, Pasini D, Dietrich N et al (2008) A model for transmission of the H3K27me3 epigenetic mark. Nat Cell Biol 10(11):1291-1300
-
(2008)
Nat Cell Biol
, vol.10
, Issue.11
, pp. 1291-1300
-
-
Hansen, K.H.1
Bracken, A.P.2
Pasini, D.3
Dietrich, N.4
-
154
-
-
70349952171
-
Role of the polycomb protein EED in the propagation of repressive histone marks
-
Margueron R, Justin N, Ohno K, Sharpe ML et al (2009) Role of the polycomb protein EED in the propagation of repressive histone marks. Nature 461(7265):762-767
-
(2009)
Nature
, vol.461
, Issue.7265
, pp. 762-767
-
-
Margueron, R.1
Justin, N.2
Ohno, K.3
Sharpe, M.L.4
-
155
-
-
0043127085
-
Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains
-
Fischle W, Wang Y, Jacobs SA, Kim Y et al (2003) Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev 17(15): 1870-1881
-
(2003)
Genes Dev
, vol.17
, Issue.15
, pp. 1870-1881
-
-
Fischle, W.1
Wang, Y.2
Jacobs, S.A.3
Kim, Y.4
-
156
-
-
80051679799
-
Long noncoding RNA, polycomb, and the ghosts haunting INK4b-ARFINK4a expression
-
Aguilo F, Zhou MM, Walsh MJ (2011) Long noncoding RNA, polycomb, and the ghosts haunting INK4b-ARFINK4a expression. Cancer Res 71(16):5365-5369
-
(2011)
Cancer Res
, vol.71
, Issue.16
, pp. 5365-5369
-
-
Aguilo, F.1
Zhou, M.M.2
Walsh, M.J.3
-
157
-
-
79960805226
-
DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response
-
Loughery JE, Dunne PD, O'Neill KM, Meehan RR et al (2011) DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response. Hum Mol Genet 20(16): 3241-3255
-
(2011)
Hum Mol Genet
, vol.20
, Issue.16
, pp. 3241-3255
-
-
Loughery, J.E.1
Dunne, P.D.2
O'Neill, K.M.3
Meehan, R.R.4
-
158
-
-
79960484375
-
Gene silencing in X-chromosome inactivation: Advances in understanding facultative heterochromatin formation
-
Wutz A (2011) Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation. Nat Rev 12(8):542-553
-
(2011)
Nat Rev
, vol.12
, Issue.8
, pp. 542-553
-
-
Wutz, A.1
-
159
-
-
33746076412
-
A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced
-
Chaumeil J, Le Baccon P, Wutz A, Heard E (2006) A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced. Genes Dev 20(16):2223-2237
-
(2006)
Genes Dev
, vol.20
, Issue.16
, pp. 2223-2237
-
-
Chaumeil, J.1
Le Baccon, P.2
Wutz, A.3
Heard, E.4
-
160
-
-
77950354829
-
The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation
-
Pullirsch D, Hartel R, Kishimoto H, Leeb M et al (2010) The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation. Development (Cambridge, England) 137(6):935-943
-
(2010)
Development (Cambridge, England)
, vol.137
, Issue.6
, pp. 935-943
-
-
Pullirsch, D.1
Hartel, R.2
Kishimoto, H.3
Leeb, M.4
-
161
-
-
0032805149
-
Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation
-
Csankovszki G, Panning B, Bates B, Pehrson JR et al (1999) Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation. Nat Genet 22(4):323-324
-
(1999)
Nat Genet
, vol.22
, Issue.4
, pp. 323-324
-
-
Csankovszki, G.1
Panning, B.2
Bates, B.3
Pehrson, J.R.4
-
162
-
-
77952425747
-
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
-
Stadtfeld M, Apostolou E, Akutsu H, Fukuda A et al (2010) Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature 465(7295):175-181
-
(2010)
Nature
, vol.465
, Issue.7295
, pp. 175-181
-
-
Stadtfeld, M.1
Apostolou, E.2
Akutsu, H.3
Fukuda, A.4
-
163
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
Kim K, Doi A, Wen B, Ng K et al (2010) Epigenetic memory in induced pluripotent stem cells. Nature 467(7313):285-290
-
(2010)
Nature
, vol.467
, Issue.7313
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen, B.3
Ng, K.4
-
164
-
-
79959992876
-
Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells
-
Bar-Nur O, Russ HA, Efrat S, Benvenisty N (2011) Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells. Cell Stem Cell 9(1):17-23
-
(2011)
Cell Stem Cell
, vol.9
, Issue.1
, pp. 17-23
-
-
Bar-Nur, O.1
Russ, H.A.2
Efrat, S.3
Benvenisty, N.4
-
165
-
-
72849144528
-
Clone-and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells
-
Pick M, Stelzer Y, Bar-Nur O, Mayshar Y et al (2009) Clone-and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells. Stem Cells (Dayton, OH) 27(11):2686-2690
-
(2009)
Stem Cells (Dayton, OH
, vol.27
, Issue.11
, pp. 2686-2690
-
-
Pick, M.1
Stelzer, Y.2
Bar-Nur, O.3
Mayshar, Y.4
-
166
-
-
85027958626
-
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
-
Ohi Y, Qin H, Hong C, Blouin L et al (2011) Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells. Nat Cell Biol 13(5):541-549
-
(2011)
Nat Cell Biol
, vol.13
, Issue.5
, pp. 541-549
-
-
Ohi, Y.1
Qin, H.2
Hong, C.3
Blouin, L.4
-
167
-
-
79961133928
-
Unexpected X chromosome skewing during culture and reprogramming of human somatic cells can be alleviated by exogenous telomerase
-
Pomp O, Dreesen O, Leong DF, Meller-Pomp O et al (2011) Unexpected X chromosome skewing during culture and reprogramming of human somatic cells can be alleviated by exogenous telomerase. Cell Stem Cell 9(2):156-165
-
(2011)
Cell Stem Cell
, vol.9
, Issue.2
, pp. 156-165
-
-
Pomp, O.1
Dreesen, O.2
Leong, D.F.3
Meller-Pomp, O.4
-
168
-
-
77956222202
-
Female human iPSCs retain an inactive X chromosome
-
Tchieu J, Kuoy E, Chin MH, Trinh H et al (2010) Female human iPSCs retain an inactive X chromosome. Cell Stem Cell 7(3):329-342
-
(2010)
Cell Stem Cell
, vol.7
, Issue.3
, pp. 329-342
-
-
Tchieu, J.1
Kuoy, E.2
Chin, M.H.3
Trinh, H.4
-
169
-
-
80053900492
-
Direct lineage conversion of terminally differentiated hepatocytes to functional neurons
-
Marro S, Pang ZP, Yang N, Tsai MC et al (2011) Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Cell Stem Cell 9(4):374-382
-
(2011)
Cell Stem Cell
, vol.9
, Issue.4
, pp. 374-382
-
-
Marro, S.1
Pang, Z.P.2
Yang, N.3
Tsai, M.C.4
-
170
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y et al (2010) Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463(7284): 1035-1041
-
(2010)
Nature
, vol.463
, Issue.7284
, pp. 1035-1041
-
-
Vierbuchen, T.1
Ostermeier, A.2
Pang, Z.P.3
Kokubu, Y.4
-
171
-
-
77953096509
-
Adult cell fate reprogramming: Converting liver to pancreas
-
Meivar-Levy I, Ferber S (2010) Adult cell fate reprogramming: converting liver to pancreas. Methods Mol Biol (Clifton, NJ) 636:251-283
-
(2010)
Methods Mol Biol (Clifton, NJ
, vol.636
, pp. 251-283
-
-
Meivar-Levy, I.1
Ferber, S.2
-
172
-
-
79956318370
-
De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state
-
Pawlak M, Jaenisch R (2011) De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state. Genes Dev 25(10):1035-1040
-
(2011)
Genes Dev
, vol.25
, Issue.10
, pp. 1035-1040
-
-
Pawlak, M.1
Jaenisch, R.2
-
173
-
-
77953086963
-
ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency
-
Pereira CF, Piccolo FM, Tsubouchi T, Sauer S et al (2010) ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency. Cell Stem Cell 6(6):547-556
-
(2010)
Cell Stem Cell
, vol.6
, Issue.6
, pp. 547-556
-
-
Pereira, C.F.1
Piccolo, F.M.2
Tsubouchi, T.3
Sauer, S.4
-
174
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan M, Luo H, Lee S, Jin F et al (2011) Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 146(6): 1016-1028
-
(2011)
Cell
, vol.146
, Issue.6
, pp. 1016-1028
-
-
Tan, M.1
Luo, H.2
Lee, S.3
Jin, F.4
-
175
-
-
80054718001
-
Chromatin: A haul of new histone modifications
-
Muers M (2011) Chromatin: a haul of new histone modifications. Nat Rev 12(11):744
-
(2011)
Nat Rev
, vol.12
, Issue.11
, pp. 744
-
-
Muers, M.1
-
176
-
-
28844475262
-
Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin
-
Hirota T, Lipp JJ, Toh BH, Peters JM (2005) Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin. Nature 438(7071):1176-1180
-
(2005)
Nature
, vol.438
, Issue.7071
, pp. 1176-1180
-
-
Hirota, T.1
Lipp, J.J.2
Toh, B.H.3
Peters, J.M.4
-
177
-
-
28844477653
-
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation
-
Fischle W, Tseng BS, Dormann HL, Ueberheide BM et al (2005) Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature 438(7071):1116-1122
-
(2005)
Nature
, vol.438
, Issue.7071
, pp. 1116-1122
-
-
Fischle, W.1
Tseng, B.S.2
Dormann, H.L.3
Ueberheide, B.M.4
-
178
-
-
80054097425
-
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
-
Inoue A, Zhang Y (2011) Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science (New York, NY) 334(6053):194
-
(2011)
Science (New York, NY)
, vol.334
, Issue.6053
, pp. 194
-
-
Inoue, A.1
Zhang, Y.2
-
179
-
-
74049165069
-
Ontogeny of haematopoiesis: Recent advances and open questions
-
Ottersbach K, Smith A, Wood A, Gottgens B (2011) Ontogeny of haematopoiesis: recent advances and open questions. Br J Haematol 148(3):343-355
-
(2011)
Br J Haematol
, vol.148
, Issue.3
, pp. 343-355
-
-
Ottersbach, K.1
Smith, A.2
Wood, A.3
Gottgens, B.4
|