Mitotically stable association of polycomb group proteins Eed and Enx1 with the inactive X chromosome in trophoblast stem cells

Current Biology

Volumn 12, Issue 12, 2002, Pages 1016-1020

  Mak, Winifred ^a   Baxter, Jonathon ^b   Silva, Jose ^a   Newall, Alistair E ^a   Otte, Arie P ^c  

^a X Inactivation Group   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA;

EED PROTEIN, MOUSE; POLYCOMB GROUP PROTEINS; REPRESSOR PROTEIN;

ANIMAL; ARTICLE; CBA MOUSE; CELL LINE; CYTOLOGY; FEMALE; GENE EXPRESSION REGULATION; MALE; METABOLISM; MITOSIS; MOUSE; STEM CELL; TROPHOBLAST; X CHROMOSOME;

ANIMALS; CELL LINE; DOSAGE COMPENSATION, GENETIC; FEMALE; MALE; MICE; MICE, INBRED CBA; MITOSIS; REPRESSOR PROTEINS; STEM CELLS; TROPHOBLASTS; X CHROMOSOME;

EID: 0037172659     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00892-8     Document Type: Article

References (29)

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3. The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus
4. A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation
5. X-chromosome inactivation studied by injection of a single cell into the mouse blastocyst
6. Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse
7. Xist deficient mice are defective in dosage compensation but not spermatogenesis
8. Imprinted X inactivation maintained by a mouse polycomb group gene
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10. Chromatin structure analysis of the mouse Xist locus
11. Promotion of trophoblast stem cell proliferation by FGF4
12. Positional cloning of a global regulator of anterior posterior patterning in mice
13. Chraracterization of interactions between the mammalian Polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian Polycomb-group protein complexes
14. The Drosophila Polycomb-group proteins ESC and E(Z) bind directly to each other and colocalise at multiple chromosomal sites
15. Xist RNA exhibits a banded localization on the inactive X chromosome and is excluded from autosomal material in cis
16. Transcriptional repression mediated by the human Polycomb-Group protein EED involves histone deacetylation
17. The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3
18. The Polycomb Group protein EED interacts with YY1 and both proteins induce neural tissue in Xenopus embryos
19. Establishment of Polycomb silencing requires a transient interaction between PC and ESC
20. Stabilization of chromatin structure by PCR1 a Polycomb complex
21. X inactivation in marsupials and montremes
22. Regulation of chromatin structure by site-specific histone H3 methyltransferases
23. SET domain-containing protein G9a is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3
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26. Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation
27. Histone H3 Lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation
28. RING1 is associated with the Polycomb-group protein complex and acts as a transcriptional repressor
29. Xist yeast artificial chromosome transgenes function as X-inactivation centers only in multicopy arrays and not as single copies