-
1
-
-
28944449341
-
Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets
-
COI: 1:CAS:528:DC%2BD2MXhtlWqu7%2FL, PID: 16310802
-
Arnould S, Chames P, Perez C, Lacroix E, Duclert A, Epinat JC, Stricher F, Petit AS, Patin A, Guillier S, Rolland S, Prieto J, Blanco FJ, Bravo J, Montoya G, Serrano L, Duchateau P, Paques F (2006) Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets. J Mol Biol 355(3):443–458. doi:10.1016/j.jmb.2005.10.065
-
(2006)
J Mol Biol
, vol.355
, Issue.3
, pp. 443-458
-
-
Arnould, S.1
Chames, P.2
Perez, C.3
Lacroix, E.4
Duclert, A.5
Epinat, J.C.6
Stricher, F.7
Petit, A.S.8
Patin, A.9
Guillier, S.10
Rolland, S.11
Prieto, J.12
Blanco, F.J.13
Bravo, J.14
Montoya, G.15
Serrano, L.16
Duchateau, P.17
Paques, F.18
-
2
-
-
78650432023
-
The I-CreI meganuclease and its engineered derivatives: applications from cell modification to gene therapy
-
COI: 1:CAS:528:DC%2BC3cXhsF2rsbzI
-
Arnould S, Delenda C, Grizot S, Desseaux C, Paques F, Silva GH, Smith J (2011) The I-CreI meganuclease and its engineered derivatives: applications from cell modification to gene therapy. Protein Eng Des Sel PEDS 24(1–2):27–31. doi:10.1093/protein/gzq083
-
(2011)
Protein Eng Des Sel PEDS
, vol.24
, Issue.1-2
, pp. 27-31
-
-
Arnould, S.1
Delenda, C.2
Grizot, S.3
Desseaux, C.4
Paques, F.5
Silva, G.H.6
Smith, J.7
-
3
-
-
80755187812
-
CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation
-
COI: 1:CAS:528:DC%2BC3MXhs1ahtrrN, PID: 22060043
-
Bhaya D, Davison M, Barrangou R (2011) CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation. Annu Rev Genet 45:273–297. doi:10.1146/annurev-genet-110410-132430
-
(2011)
Annu Rev Genet
, vol.45
, pp. 273-297
-
-
Bhaya, D.1
Davison, M.2
Barrangou, R.3
-
4
-
-
0036021389
-
Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BD38XmsF2ru7c%3D, PID: 12136019
-
Bibikova M, Golic M, Golic KG, Carroll D (2002) Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases. Genetics 161(3):1169–1175
-
(2002)
Genetics
, vol.161
, Issue.3
, pp. 1169-1175
-
-
Bibikova, M.1
Golic, M.2
Golic, K.G.3
Carroll, D.4
-
5
-
-
77956126894
-
Xanthomonas AvrBs3 family-type III effectors: discovery and function
-
COI: 1:CAS:528:DC%2BC3cXht1Wgt7zN, PID: 19400638
-
Boch J, Bonas U (2010) Xanthomonas AvrBs3 family-type III effectors: discovery and function. Annu Rev Phytopathol 48:419–436. doi:10.1146/annurev-phyto-080508-081936
-
(2010)
Annu Rev Phytopathol
, vol.48
, pp. 419-436
-
-
Boch, J.1
Bonas, U.2
-
6
-
-
72149110399
-
Breaking the code of DNA binding specificity of TAL-type III effectors
-
COI: 1:CAS:528:DC%2BD1MXhsFensbnL, PID: 19933107
-
Boch J, Scholze H, Schornack S, Landgraf A, Hahn S, Kay S, Lahaye T, Nickstadt A, Bonas U (2009) Breaking the code of DNA binding specificity of TAL-type III effectors. Science 326(5959):1509–1512. doi:10.1126/science.1178811
-
(2009)
Science
, vol.326
, Issue.5959
, pp. 1509-1512
-
-
Boch, J.1
Scholze, H.2
Schornack, S.3
Landgraf, A.4
Hahn, S.5
Kay, S.6
Lahaye, T.7
Nickstadt, A.8
Bonas, U.9
-
7
-
-
78549267889
-
Targeted genome modification in mice using zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BC3cXhsFOnt7rI, PID: 20628038
-
Carbery ID, Ji D, Harrington A, Brown V, Weinstein EJ, Liaw L, Cui X (2010) Targeted genome modification in mice using zinc-finger nucleases. Genetics 186(2):451–459. doi:10.1534/genetics.110.117002
-
(2010)
Genetics
, vol.186
, Issue.2
, pp. 451-459
-
-
Carbery, I.D.1
Ji, D.2
Harrington, A.3
Brown, V.4
Weinstein, E.J.5
Liaw, L.6
Cui, X.7
-
8
-
-
84867911474
-
Efficient TALEN-mediated gene knockout in livestock
-
COI: 1:CAS:528:DC%2BC38XhvVSltL3K, PID: 23027955
-
Carlson DF, Tan W, Lillico SG, Stverakova D, Proudfoot C, Christian M, Voytas DF, Long CR, Whitelaw CB, Fahrenkrug SC (2012) Efficient TALEN-mediated gene knockout in livestock. Proc Natl Acad Sci USA 109(43):17382–17387. doi:10.1073/pnas.1211446109
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.43
, pp. 17382-17387
-
-
Carlson, D.F.1
Tan, W.2
Lillico, S.G.3
Stverakova, D.4
Proudfoot, C.5
Christian, M.6
Voytas, D.F.7
Long, C.R.8
Whitelaw, C.B.9
Fahrenkrug, S.C.10
-
9
-
-
45749145124
-
Zinc-finger nucleases: the next generation emerges
-
COI: 1:CAS:528:DC%2BD1cXns1eiu78%3D, PID: 18545224
-
Cathomen T, Joung JK (2008) Zinc-finger nucleases: the next generation emerges. Mol Ther 16(7):1200–1207. doi:10.1038/mt.2008.114
-
(2008)
Mol Ther
, vol.16
, Issue.7
, pp. 1200-1207
-
-
Cathomen, T.1
Joung, J.K.2
-
10
-
-
79960064013
-
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
-
COI: 1:CAS:528:DC%2BC3MXoslOgtLo%3D, PID: 21493687
-
Cermak T, Doyle EL, Christian M, Wang L, Zhang Y, Schmidt C, Baller JA, Somia NV, Bogdanove AJ, Voytas DF (2011) Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Res 39(12):e82. doi:10.1093/nar/gkr218
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.12
, pp. e82
-
-
Cermak, T.1
Doyle, E.L.2
Christian, M.3
Wang, L.4
Zhang, Y.5
Schmidt, C.6
Baller, J.A.7
Somia, N.V.8
Bogdanove, A.J.9
Voytas, D.F.10
-
11
-
-
0035883706
-
Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility
-
COI: 1:CAS:528:DC%2BD3MXot1eku74%3D, PID: 11557808
-
Chevalier BS, Stoddard BL (2001) Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility. Nucleic Acids Res 29(18):3757–3774
-
(2001)
Nucleic Acids Res
, vol.29
, Issue.18
, pp. 3757-3774
-
-
Chevalier, B.S.1
Stoddard, B.L.2
-
12
-
-
0028919608
-
Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae
-
COI: 1:CAS:528:DyaK2MXksFWjtrw%3D, PID: 7891691
-
Choulika A, Perrin A, Dujon B, Nicolas JF (1995) Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae. Mol Cell Biol 15(4):1968–1973
-
(1995)
Mol Cell Biol
, vol.15
, Issue.4
, pp. 1968-1973
-
-
Choulika, A.1
Perrin, A.2
Dujon, B.3
Nicolas, J.F.4
-
13
-
-
78951479577
-
Targeting DNA double-strand breaks with TAL effector nucleases
-
COI: 1:CAS:528:DC%2BC3cXhsFOnt7jP, PID: 20660643
-
Christian M, Cermak T, Doyle E, Schmidt C, Zhang F, Hummel A, Bogdanove A, Voytas D (2010) Targeting DNA double-strand breaks with TAL effector nucleases. Genetics 186(2):757–761
-
(2010)
Genetics
, vol.186
, Issue.2
, pp. 757-761
-
-
Christian, M.1
Cermak, T.2
Doyle, E.3
Schmidt, C.4
Zhang, F.5
Hummel, A.6
Bogdanove, A.7
Voytas, D.8
-
14
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
COI: 1:CAS:528:DC%2BC3sXit1ygtb8%3D, PID: 23287718
-
Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F (2013) Multiplex genome engineering using CRISPR/Cas systems. Science 339(6121):819–823. doi:10.1126/science.1231143
-
(2013)
Science
, vol.339
, Issue.6121
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
Zhang, F.11
-
15
-
-
79952107552
-
The immense potential of xenotransplantation in surgery
-
PID: 21059418
-
Cooper DK, Ayares D (2011) The immense potential of xenotransplantation in surgery. Int J Surg 9(2):122–129. doi:10.1016/j.ijsu.2010.11.002
-
(2011)
Int J Surg
, vol.9
, Issue.2
, pp. 122-129
-
-
Cooper, D.K.1
Ayares, D.2
-
16
-
-
78651322138
-
Targeted integration in rat and mouse embryos with zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BC3cXhsFGgtrbN, PID: 21151125
-
Cui X, Ji D, Fisher DA, Wu Y, Briner DM, Weinstein EJ (2011) Targeted integration in rat and mouse embryos with zinc-finger nucleases. Nat Biotechnol 29(1):64–67. doi:10.1038/nbt.1731
-
(2011)
Nat Biotechnol
, vol.29
, Issue.1
, pp. 64-67
-
-
Cui, X.1
Ji, D.2
Fisher, D.A.3
Wu, Y.4
Briner, D.M.5
Weinstein, E.J.6
-
17
-
-
3242877122
-
Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1
-
COI: 1:CAS:528:DC%2BD2cXmvVGqt7o%3D, PID: 15242397
-
De P, Rodgers KK (2004) Putting the pieces together: identification and characterization of structural domains in the V(D)J recombination protein RAG1. Immunol Rev 200:70–82. doi:10.1111/j.0105-2896.2004.00154.x
-
(2004)
Immunol Rev
, vol.200
, pp. 70-82
-
-
De, P.1
Rodgers, K.K.2
-
18
-
-
0346244098
-
The mechanisms of immune diversification and their disorders
-
PID: 14647478
-
de Villartay JP, Fischer A, Durandy A (2003) The mechanisms of immune diversification and their disorders. Nat Rev Immunol 3(12):962–972. doi:10.1038/nri1247
-
(2003)
Nat Rev Immunol
, vol.3
, Issue.12
, pp. 962-972
-
-
de Villartay, J.P.1
Fischer, A.2
Durandy, A.3
-
19
-
-
79961202364
-
Move over ZFNs
-
Defrancesco L (2011) Move over ZFNs. Nat Biotechnol 29(8):681–684
-
(2011)
Nat Biotechnol
, vol.29
, Issue.8
, pp. 681-684
-
-
Defrancesco, L.1
-
20
-
-
0026753186
-
Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus
-
COI: 1:CAS:528:DyaK38Xlt1GmtL8%3D, PID: 1321331
-
Deng C, Capecchi MR (1992) Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Mol Cell Biol 12(8):3365–3371
-
(1992)
Mol Cell Biol
, vol.12
, Issue.8
, pp. 3365-3371
-
-
Deng, C.1
Capecchi, M.R.2
-
21
-
-
0031863007
-
Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells
-
COI: 1:CAS:528:DyaK1cXkt1Wjsb4%3D, PID: 9632791
-
Donoho G, Jasin M, Berg P (1998) Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells. Mol Cell Biol 18(7):4070–4078
-
(1998)
Mol Cell Biol
, vol.18
, Issue.7
, pp. 4070-4078
-
-
Donoho, G.1
Jasin, M.2
Berg, P.3
-
22
-
-
33644507991
-
Directed evolution and substrate specificity profile of homing endonuclease I-SceI
-
COI: 1:CAS:528:DC%2BD28Xoslyjsg%3D%3D, PID: 16478204
-
Doyon JB, Pattanayak V, Meyer CB, Liu DR (2006) Directed evolution and substrate specificity profile of homing endonuclease I-SceI. J Am Chem Soc 128(7):2477–2484. doi:10.1021/ja057519l
-
(2006)
J Am Chem Soc
, vol.128
, Issue.7
, pp. 2477-2484
-
-
Doyon, J.B.1
Pattanayak, V.2
Meyer, C.B.3
Liu, D.R.4
-
23
-
-
44949155482
-
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BD1cXmvVCis7g%3D, PID: 18500334
-
Doyon Y, McCammon JM, Miller JC, Faraji F, Ngo C, Katibah GE, Amora R, Hocking TD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Amacher SL (2008) Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases. Nat Biotechnol 26(6):702–708. doi:10.1038/nbt1409
-
(2008)
Nat Biotechnol
, vol.26
, Issue.6
, pp. 702-708
-
-
Doyon, Y.1
McCammon, J.M.2
Miller, J.C.3
Faraji, F.4
Ngo, C.5
Katibah, G.E.6
Amora, R.7
Hocking, T.D.8
Zhang, L.9
Rebar, E.J.10
Gregory, P.D.11
Urnov, F.D.12
Amacher, S.L.13
-
24
-
-
77953023690
-
Transient cold shock enhances zinc-finger nuclease-mediated gene disruption
-
COI: 1:CAS:528:DC%2BC3cXlsVyhs70%3D, PID: 20436476
-
Doyon Y, Choi VM, Xia DF, Vo TD, Gregory PD, Holmes MC (2010) Transient cold shock enhances zinc-finger nuclease-mediated gene disruption. Nat Methods 7(6):459–460
-
(2010)
Nat Methods
, vol.7
, Issue.6
, pp. 459-460
-
-
Doyon, Y.1
Choi, V.M.2
Xia, D.F.3
Vo, T.D.4
Gregory, P.D.5
Holmes, M.C.6
-
25
-
-
0038268049
-
A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells
-
COI: 1:CAS:528:DC%2BD3sXkt1Wqsrw%3D, PID: 12771221
-
Epinat JC, Arnould S, Chames P, Rochaix P, Desfontaines D, Puzin C, Patin A, Zanghellini A, Paques F, Lacroix E (2003) A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells. Nucleic Acids Res 31(11):2952–2962
-
(2003)
Nucleic Acids Res
, vol.31
, Issue.11
, pp. 2952-2962
-
-
Epinat, J.C.1
Arnould, S.2
Chames, P.3
Rochaix, P.4
Desfontaines, D.5
Puzin, C.6
Patin, A.7
Zanghellini, A.8
Paques, F.9
Lacroix, E.10
-
26
-
-
43449100659
-
A system for the construction of targeted unmarked gene deletions in the genus Burkholderia
-
COI: 1:CAS:528:DC%2BD1cXnvVWku78%3D, PID: 18341581
-
Flannagan RS, Linn T, Valvano MA (2008) A system for the construction of targeted unmarked gene deletions in the genus Burkholderia. Environ Microbiol 10(6):1652–1660. doi:10.1111/j.1462-2920.2008.01576.x
-
(2008)
Environ Microbiol
, vol.10
, Issue.6
, pp. 1652-1660
-
-
Flannagan, R.S.1
Linn, T.2
Valvano, M.A.3
-
27
-
-
79958695683
-
Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases
-
COI: 1:CAS:528:DC%2BC3MXnvVOht7c%3D, PID: 21695153
-
Flisikowska T, Thorey IS, Offner S, Ros F, Lifke V, Zeitler B, Rottmann O, Vincent A, Zhang L, Jenkins S, Niersbach H, Kind AJ, Gregory PD, Schnieke AE, Platzer J (2011) Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases. PLoS ONE 6(6):e21045. doi:10.1371/journal.pone.0021045
-
(2011)
PLoS ONE
, vol.6
, Issue.6
, pp. e21045
-
-
Flisikowska, T.1
Thorey, I.S.2
Offner, S.3
Ros, F.4
Lifke, V.5
Zeitler, B.6
Rottmann, O.7
Vincent, A.8
Zhang, L.9
Jenkins, S.10
Niersbach, H.11
Kind, A.J.12
Gregory, P.D.13
Schnieke, A.E.14
Platzer, J.15
-
28
-
-
84867185165
-
A porcine model of familial adenomatous polyposis
-
COI: 1:CAS:528:DC%2BC38XhsFGjsLzN, PID: 22864254
-
Flisikowska T, Merkl C, Landmann M, Eser S, Rezaei N, Cui X, Kurome M, Zakhartchenko V, Kessler B, Wieland H, Rottmann O, Schmid RM, Schneider G, Kind A, Wolf E, Saur D, Schnieke A (2012) A porcine model of familial adenomatous polyposis. Gastroenterology 143(5):1173–1175. doi:10.1053/j.gastro.2012.07.110
-
(2012)
Gastroenterology
, vol.143
, Issue.5
, pp. 1173-1175
-
-
Flisikowska, T.1
Merkl, C.2
Landmann, M.3
Eser, S.4
Rezaei, N.5
Cui, X.6
Kurome, M.7
Zakhartchenko, V.8
Kessler, B.9
Wieland, H.10
Rottmann, O.11
Schmid, R.M.12
Schneider, G.13
Kind, A.14
Wolf, E.15
Saur, D.16
Schnieke, A.17
-
29
-
-
84893618608
-
Genetically modified pigs to model human diseases
-
PID: 24234401
-
Flisikowska T, Kind A, Schnieke A (2014) Genetically modified pigs to model human diseases. J Appl Genet 55(1):53–64. doi:10.1007/s13353-013-0182-9
-
(2014)
J Appl Genet
, vol.55
, Issue.1
, pp. 53-64
-
-
Flisikowska, T.1
Kind, A.2
Schnieke, A.3
-
30
-
-
84896929630
-
Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
-
COI: 1:CAS:528:DC%2BC2cXht1yru78%3D, PID: 24463574
-
Fu Y, Sander JD, Reyon D, Cascio VM, Joung JK (2014) Improving CRISPR-Cas nuclease specificity using truncated guide RNAs. Nat Biotechnol 32(3):279–284. doi:10.1038/nbt.2808
-
(2014)
Nat Biotechnol
, vol.32
, Issue.3
, pp. 279-284
-
-
Fu, Y.1
Sander, J.D.2
Reyon, D.3
Cascio, V.M.4
Joung, J.K.5
-
31
-
-
67749106611
-
Knockout rats via embryo microinjection of zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BD1MXovVChtrY%3D, PID: 19628861
-
Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, Jenkins SS, Wood A, Cui X, Meng X, Vincent A, Lam S, Michalkiewicz M, Schilling R, Foeckler J, Kalloway S, Weiler H, Menoret S, Anegon I, Davis GD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jacob HJ, Buelow R (2009) Knockout rats via embryo microinjection of zinc-finger nucleases. Science 325(5939):433. doi:10.1126/science.1172447
-
(2009)
Science
, vol.325
, Issue.5939
, pp. 433
-
-
Geurts, A.M.1
Cost, G.J.2
Freyvert, Y.3
Zeitler, B.4
Miller, J.C.5
Choi, V.M.6
Jenkins, S.S.7
Wood, A.8
Cui, X.9
Meng, X.10
Vincent, A.11
Lam, S.12
Michalkiewicz, M.13
Schilling, R.14
Foeckler, J.15
Kalloway, S.16
Weiler, H.17
Menoret, S.18
Anegon, I.19
Davis, G.D.20
Zhang, L.21
Rebar, E.J.22
Gregory, P.D.23
Urnov, F.D.24
Jacob, H.J.25
Buelow, R.26
more..
-
32
-
-
58249090930
-
Recent advances in meganuclease-and transposon-mediated transgenesis of medaka and zebrafish
-
COI: 1:CAS:528:DC%2BD1cXhtl2gtb%2FN
-
Grabher C, Wittbrodt J (2008) Recent advances in meganuclease-and transposon-mediated transgenesis of medaka and zebrafish. Methods Mol Biol (Clifton, NJ) 461:521–539. doi:10.1007/978-1-60327-483-8_36
-
(2008)
Methods Mol Biol (Clifton, NJ)
, vol.461
, pp. 521-539
-
-
Grabher, C.1
Wittbrodt, J.2
-
33
-
-
70349407359
-
Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease
-
COI: 1:CAS:528:DC%2BD1MXht1Oqs7zL, PID: 19584299
-
Grizot S, Smith J, Daboussi F, Prieto J, Redondo P, Merino N, Villate M, Thomas S, Lemaire L, Montoya G, Blanco FJ, Paques F, Duchateau P (2009) Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease. Nucleic Acids Res 37(16):5405–5419. doi:10.1093/nar/gkp548
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.16
, pp. 5405-5419
-
-
Grizot, S.1
Smith, J.2
Daboussi, F.3
Prieto, J.4
Redondo, P.5
Merino, N.6
Villate, M.7
Thomas, S.8
Lemaire, L.9
Montoya, G.10
Blanco, F.J.11
Paques, F.12
Duchateau, P.13
-
34
-
-
84902210542
-
Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification
-
Guilinger JP, Thompson DB, Liu DR (2014) Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification. Nat Biotechnol. doi:10.1038/nbt.2909
-
(2014)
Nat Biotechnol
-
-
Guilinger, J.P.1
Thompson, D.B.2
Liu, D.R.3
-
35
-
-
84897594300
-
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system
-
COI: 1:CAS:528:DC%2BC2cXhsl2gsLk%3D, PID: 24481528
-
Hai T, Teng F, Guo R, Li W, Zhou Q (2014) One-step generation of knockout pigs by zygote injection of CRISPR/Cas system. Cell Res 24(3):372–375. doi:10.1038/cr.2014.11
-
(2014)
Cell Res
, vol.24
, Issue.3
, pp. 372-375
-
-
Hai, T.1
Teng, F.2
Guo, R.3
Li, W.4
Zhou, Q.5
-
36
-
-
79961079857
-
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BC3MXpsFyku7o%3D, PID: 21730124
-
Hauschild J, Petersen B, Santiago Y, Queisser AL, Carnwath JW, Lucas-Hahn A, Zhang L, Meng X, Gregory PD, Schwinzer R, Cost GJ, Niemann H (2011) Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases. Proc Natl Acad Sci USA 108(29):12013–12017. doi:10.1073/pnas.1106422108
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.29
, pp. 12013-12017
-
-
Hauschild, J.1
Petersen, B.2
Santiago, Y.3
Queisser, A.L.4
Carnwath, J.W.5
Lucas-Hahn, A.6
Zhang, L.7
Meng, X.8
Gregory, P.D.9
Schwinzer, R.10
Cost, G.J.11
Niemann, H.12
-
37
-
-
84881147545
-
Gene knockout and knockin by zinc-finger nucleases: current status and perspectives
-
COI: 1:CAS:528:DC%2BC3sXhtFKlu77M, PID: 23161061
-
Hauschild-Quintern J, Petersen B, Cost GJ, Niemann H (2013a) Gene knockout and knockin by zinc-finger nucleases: current status and perspectives. Cell Mol Life Sci 70(16):2969–2983. doi:10.1007/s00018-012-1204-1
-
(2013)
Cell Mol Life Sci
, vol.70
, Issue.16
, pp. 2969-2983
-
-
Hauschild-Quintern, J.1
Petersen, B.2
Cost, G.J.3
Niemann, H.4
-
38
-
-
84871398668
-
Gender non-specific efficacy of ZFN mediated gene targeting in pigs
-
COI: 1:CAS:528:DC%2BC38XhvVCqsLbF, PID: 22972477
-
Hauschild-Quintern J, Petersen B, Queisser AL, Lucas-Hahn A, Schwinzer R, Niemann H (2013b) Gender non-specific efficacy of ZFN mediated gene targeting in pigs. Transgenic Res 22(1):1–3. doi:10.1007/s11248-012-9647-6
-
(2013)
Transgenic Res
, vol.22
, Issue.1
-
-
Hauschild-Quintern, J.1
Petersen, B.2
Queisser, A.L.3
Lucas-Hahn, A.4
Schwinzer, R.5
Niemann, H.6
-
39
-
-
79960836456
-
Genetic engineering of human pluripotent cells using TALE nucleases
-
COI: 1:CAS:528:DC%2BC3MXos1Srs7o%3D, PID: 21738127
-
Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, Cassady JP, Cost GJ, Zhang L, Santiago Y, Miller JC, Zeitler B, Cherone JM, Meng X, Hinkley SJ, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R (2011) Genetic engineering of human pluripotent cells using TALE nucleases. Nat Biotechnol 29(8):731–734. doi:10.1038/nbt.1927
-
(2011)
Nat Biotechnol
, vol.29
, Issue.8
, pp. 731-734
-
-
Hockemeyer, D.1
Wang, H.2
Kiani, S.3
Lai, C.S.4
Gao, Q.5
Cassady, J.P.6
Cost, G.J.7
Zhang, L.8
Santiago, Y.9
Miller, J.C.10
Zeitler, B.11
Cherone, J.M.12
Meng, X.13
Hinkley, S.J.14
Rebar, E.J.15
Gregory, P.D.16
Urnov, F.D.17
Jaenisch, R.18
-
40
-
-
71749093470
-
Utilization of an unstable plasmid and the I-SceI endonuclease to generate routine markerless deletion mutants in Francisella tularensis
-
COI: 1:CAS:528:DC%2BD1MXhsFyksbvN, PID: 19879904
-
Horzempa J, Shanks RM, Brown MJ, Russo BC, O’Dee DM, Nau GJ (2010) Utilization of an unstable plasmid and the I-SceI endonuclease to generate routine markerless deletion mutants in Francisella tularensis. J Microbiol Methods 80(1):106–108. doi:10.1016/j.mimet.2009.10.013
-
(2010)
J Microbiol Methods
, vol.80
, Issue.1
, pp. 106-108
-
-
Horzempa, J.1
Shanks, R.M.2
Brown, M.J.3
Russo, B.C.4
O’Dee, D.M.5
Nau, G.J.6
-
41
-
-
79961185942
-
Heritable gene targeting in zebrafish using customized TALENs
-
PID: 21822242
-
Huang P, Xiao A, Zhou M, Zhu Z, Lin S, Zhang B (2011) Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol 29(8):699–700. doi:10.1038/nbt.1939
-
(2011)
Nat Biotechnol
, vol.29
, Issue.8
, pp. 699-700
-
-
Huang, P.1
Xiao, A.2
Zhou, M.3
Zhu, Z.4
Lin, S.5
Zhang, B.6
-
42
-
-
0022399493
-
An intron-encoded protein is active in a gene conversion process that spreads an intron into a mitochondrial gene
-
COI: 1:CAS:528:DyaL2MXkvF2mtrs%3D, PID: 3886163
-
Jacquier A, Dujon B (1985) An intron-encoded protein is active in a gene conversion process that spreads an intron into a mitochondrial gene. Cell 41(2):383–394
-
(1985)
Cell
, vol.41
, Issue.2
, pp. 383-394
-
-
Jacquier, A.1
Dujon, B.2
-
43
-
-
84876567971
-
RNA-programmed genome editing in human cells
-
PID: 23386978
-
Jinek M, East A, Cheng A, Lin S, Ma E, Doudna J (2013) RNA-programmed genome editing in human cells. Elife 2:e00471. doi:10.7554/eLife.00471
-
(2013)
Elife
, vol.2
, pp. e00471
-
-
Jinek, M.1
East, A.2
Cheng, A.3
Lin, S.4
Ma, E.5
Doudna, J.6
-
44
-
-
0030032063
-
Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain
-
COI: 1:CAS:528:DyaK28Xptl2luw%3D%3D, PID: 8577732
-
Kim YG, Cha J, Chandrasegaran S (1996) Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain. Proc Natl Acad Sci USA 93(3):1156–1160
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.3
, pp. 1156-1160
-
-
Kim, Y.G.1
Cha, J.2
Chandrasegaran, S.3
-
45
-
-
84875157258
-
A library of TAL effector nucleases spanning the human genome
-
COI: 1:CAS:528:DC%2BC3sXjtlKksbs%3D, PID: 23417094
-
Kim Y, Kweon J, Kim A, Chon JK, Yoo JY, Kim HJ, Kim S, Lee C, Jeong E, Chung E, Kim D, Lee MS, Go EM, Song HJ, Kim H, Cho N, Bang D, Kim S, Kim JS (2013) A library of TAL effector nucleases spanning the human genome. Nat Biotechnol 31(3):251–258. doi:10.1038/nbt.2517
-
(2013)
Nat Biotechnol
, vol.31
, Issue.3
, pp. 251-258
-
-
Kim, Y.1
Kweon, J.2
Kim, A.3
Chon, J.K.4
Yoo, J.Y.5
Kim, H.J.6
Kim, S.7
Lee, C.8
Jeong, E.9
Chung, E.10
Kim, D.11
Lee, M.S.12
Go, E.M.13
Song, H.J.14
Kim, H.15
Cho, N.16
Bang, D.17
Kim, S.18
Kim, J.S.19
-
46
-
-
84877857083
-
Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set
-
COI: 1:CAS:528:DC%2BC3sXhtFKktLrE, PID: 23688045
-
Kurome M, Geistlinger L, Kessler B, Zakhartchenko V, Klymiuk N, Wuensch A, Richter A, Baehr A, Kraehe K, Burkhardt K, Flisikowski K, Flisikowska T, Merkl C, Landmann M, Durkovic M, Tschukes A, Kraner S, Schindelhauer D, Petri T, Kind A, Nagashima H, Schnieke A, Zimmer R, Wolf E (2013) Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set. BMC Biotechnol 13:43. doi:10.1186/1472-6750-13-43
-
(2013)
BMC Biotechnol
, vol.13
, pp. 43
-
-
Kurome, M.1
Geistlinger, L.2
Kessler, B.3
Zakhartchenko, V.4
Klymiuk, N.5
Wuensch, A.6
Richter, A.7
Baehr, A.8
Kraehe, K.9
Burkhardt, K.10
Flisikowski, K.11
Flisikowska, T.12
Merkl, C.13
Landmann, M.14
Durkovic, M.15
Tschukes, A.16
Kraner, S.17
Schindelhauer, D.18
Petri, T.19
Kind, A.20
Nagashima, H.21
Schnieke, A.22
Zimmer, R.23
Wolf, E.24
more..
-
47
-
-
78651270582
-
TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
-
PID: 20699274
-
Li T, Huang S, Jiang WZ, Wright D, Spalding MH, Weeks DP, Yang B (2011a) TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain. Nucleic Acids Res 39(1):359–372. doi:10.1093/nar/gkq704
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.1
, pp. 359-372
-
-
Li, T.1
Huang, S.2
Jiang, W.Z.3
Wright, D.4
Spalding, M.H.5
Weeks, D.P.6
Yang, B.7
-
48
-
-
79960034141
-
Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes
-
COI: 1:CAS:528:DC%2BC3MXhtVeiu7%2FP, PID: 21459844
-
Li T, Huang S, Zhao X, Wright DA, Carpenter S, Spalding MH, Weeks DP, Yang B (2011b) Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes. Nucleic Acids Res 39(14):6315–6325. doi:10.1093/nar/gkr188
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.14
, pp. 6315-6325
-
-
Li, T.1
Huang, S.2
Zhao, X.3
Wright, D.A.4
Carpenter, S.5
Spalding, M.H.6
Weeks, D.P.7
Yang, B.8
-
49
-
-
84922755847
-
Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selection
-
Li P, Estrada JL, Burlak C, Montgomery J, Butler JR, Santos RM, Wang ZY, Paris LL, Blankenship RL, Downey SM, Tector M, Tector AJ (2014) Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selection. Xenotransplantation. doi:10.1111/xen.12131
-
(2014)
Xenotransplantation
-
-
Li, P.1
Estrada, J.L.2
Burlak, C.3
Montgomery, J.4
Butler, J.R.5
Santos, R.M.6
Wang, Z.Y.7
Paris, L.L.8
Blankenship, R.L.9
Downey, S.M.10
Tector, M.11
Tector, A.J.12
-
50
-
-
84892942429
-
Live pigs produced from genome edited zygotes
-
PID: 24108318
-
Lillico SG, Proudfoot C, Carlson DF, Stverakova D, Neil C, Blain C, King TJ, Ritchie WA, Tan W, Mileham AJ, McLaren DG, Fahrenkrug SC, Whitelaw CB (2013) Live pigs produced from genome edited zygotes. Sci Rep 3:2847. doi:10.1038/srep02847
-
(2013)
Sci Rep
, vol.3
, pp. 2847
-
-
Lillico, S.G.1
Proudfoot, C.2
Carlson, D.F.3
Stverakova, D.4
Neil, C.5
Blain, C.6
King, T.J.7
Ritchie, W.A.8
Tan, W.9
Mileham, A.J.10
McLaren, D.G.11
Fahrenkrug, S.C.12
Whitelaw, C.B.13
-
51
-
-
84886931066
-
Zinc-finger nickase-mediated insertion of the lysostaphin gene into the beta-casein locus in cloned cows
-
PID: 24121612
-
Liu X, Wang Y, Guo W, Chang B, Liu J, Guo Z, Quan F, Zhang Y (2013) Zinc-finger nickase-mediated insertion of the lysostaphin gene into the beta-casein locus in cloned cows. Nat Commun 4:2565. doi:10.1038/ncomms3565
-
(2013)
Nat Commun
, vol.4
, pp. 2565
-
-
Liu, X.1
Wang, Y.2
Guo, W.3
Chang, B.4
Liu, J.5
Guo, Z.6
Quan, F.7
Zhang, Y.8
-
52
-
-
70349254331
-
Generation of transgenic frogs
-
COI: 1:CAS:528:DC%2BC3cXhvVKgtb8%3D
-
Loeber J, Pan FC, Pieler T (2009) Generation of transgenic frogs. Methods Mol Biol Clifton NJ 561:65–72. doi:10.1007/978-1-60327-019-9_4
-
(2009)
Methods Mol Biol (Clifton NJ
, vol.561
, pp. 65-72
-
-
Loeber, J.1
Pan, F.C.2
Pieler, T.3
-
53
-
-
84860889144
-
Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Gottingen fibroblasts with slightly different target sequences
-
COI: 1:CAS:528:DC%2BC38Xms12gt7c%3D, PID: 22020980
-
Luo Y, Bolund L, Sorensen CB (2012) Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Gottingen fibroblasts with slightly different target sequences. Transgenic Res 21(3):671–676. doi:10.1007/s11248-011-9563-1
-
(2012)
Transgenic Res
, vol.21
, Issue.3
, pp. 671-676
-
-
Luo, Y.1
Bolund, L.2
Sorensen, C.B.3
-
54
-
-
49649118775
-
Methods for homologous recombination in Drosophila
-
COI: 1:CAS:528:DC%2BD1cXmtF2jt70%3D
-
Maggert KA, Gong WJ, Golic KG (2008) Methods for homologous recombination in Drosophila. Methods Mol Biol (Clifton NJ) 420:155–174. doi:10.1007/978-1-59745-583-1_9
-
(2008)
Methods Mol Biol (Clifton NJ)
, vol.420
, pp. 155-174
-
-
Maggert, K.A.1
Gong, W.J.2
Golic, K.G.3
-
55
-
-
79952302385
-
De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
-
COI: 1:CAS:528:DC%2BC3MXitFelu74%3D, PID: 21262818
-
Mahfouz MM, Li L, Shamimuzzaman M, Wibowo A, Fang X, Zhu JK (2011) De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks. Proc Natl Acad Sci USA 108(6):2623–2628. doi:10.1073/pnas.1019533108
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.6
, pp. 2623-2628
-
-
Mahfouz, M.M.1
Li, L.2
Shamimuzzaman, M.3
Wibowo, A.4
Fang, X.5
Zhu, J.K.6
-
56
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
COI: 1:CAS:528:DC%2BC3sXit1ygtb0%3D, PID: 23287722
-
Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM (2013) RNA-guided human genome engineering via Cas9. Science 339(6121):823–826. doi:10.1126/science.1232033
-
(2013)
Science
, vol.339
, Issue.6121
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
57
-
-
44949162060
-
Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BD1cXmvVCju7o%3D, PID: 18500337
-
Meng X, Noyes MB, Zhu LJ, Lawson ND, Wolfe SA (2008) Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases. Nat Biotechnol 26(6):695–701. doi:10.1038/nbt1398
-
(2008)
Nat Biotechnol
, vol.26
, Issue.6
, pp. 695-701
-
-
Meng, X.1
Noyes, M.B.2
Zhu, L.J.3
Lawson, N.D.4
Wolfe, S.A.5
-
58
-
-
84873467162
-
Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases
-
COI: 1:CAS:528:DC%2BC3sXit1Skurc%3D, PID: 23150522
-
Menoret S, Fontaniere S, Jantz D, Tesson L, Thinard R, Remy S, Usal C, Ouisse LH, Fraichard A, Anegon I (2013) Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases. FASEB J 27(2):703–711. doi:10.1096/fj.12-219907
-
(2013)
FASEB J
, vol.27
, Issue.2
, pp. 703-711
-
-
Menoret, S.1
Fontaniere, S.2
Jantz, D.3
Tesson, L.4
Thinard, R.5
Remy, S.6
Usal, C.7
Ouisse, L.H.8
Fraichard, A.9
Anegon, I.10
-
59
-
-
0141916932
-
A general model for genetic recombination
-
COI: 1:CAS:528:DyaE2MXhtVOksro%3D, PID: 1054510
-
Meselson MS, Radding CM (1975) A general model for genetic recombination. Proc Natl Acad Sci USA 72(1):358–361
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, Issue.1
, pp. 358-361
-
-
Meselson, M.S.1
Radding, C.M.2
-
60
-
-
77957005768
-
Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BC3cXhtFSmt7vP, PID: 20686113
-
Meyer M, de Angelis MH, Wurst W, Kuhn R (2010) Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases. Proc Natl Acad Sci USA 107(34):15022–15026. doi:10.1073/pnas.1009424107
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.34
, pp. 15022-15026
-
-
Meyer, M.1
de Angelis, M.H.2
Wurst, W.3
Kuhn, R.4
-
61
-
-
0033031162
-
MPTP-induced Parkinsonism in minipigs: a behavioral, biochemical, and histological study
-
COI: 1:CAS:528:DyaK1MXitVSrtLk%3D, PID: 10192277
-
Mikkelsen M, Moller A, Jensen LH, Pedersen A, Harajehi JB, Pakkenberg H (1999) MPTP-induced Parkinsonism in minipigs: a behavioral, biochemical, and histological study. Neurotoxicol Teratol 21(2):169–175
-
(1999)
Neurotoxicol Teratol
, vol.21
, Issue.2
, pp. 169-175
-
-
Mikkelsen, M.1
Moller, A.2
Jensen, L.H.3
Pedersen, A.4
Harajehi, J.B.5
Pakkenberg, H.6
-
62
-
-
0040215628
-
Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes
-
COI: 1:CAS:528:DyaL2MXltlKgs78%3D, PID: 4040853
-
Miller J, McLachlan AD, Klug A (1985) Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J 4(6):1609–1614
-
(1985)
EMBO J
, vol.4
, Issue.6
, pp. 1609-1614
-
-
Miller, J.1
McLachlan, A.D.2
Klug, A.3
-
63
-
-
79551685675
-
A TALE nuclease architecture for efficient genome editing
-
COI: 1:CAS:528:DC%2BC3cXhs1WisrvI, PID: 21179091
-
Miller JC, Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, Zhang HS, Holmes MC, Zhang L, Gregory PD, Rebar EJ (2011) A TALE nuclease architecture for efficient genome editing. Nat Biotechnol 29(2):143–148. doi:10.1038/nbt.1755
-
(2011)
Nat Biotechnol
, vol.29
, Issue.2
, pp. 143-148
-
-
Miller, J.C.1
Tan, S.2
Qiao, G.3
Barlow, K.A.4
Wang, J.5
Xia, D.F.6
Meng, X.7
Paschon, D.E.8
Leung, E.9
Hinkley, S.J.10
Dulay, G.P.11
Hua, K.L.12
Ankoudinova, I.13
Cost, G.J.14
Urnov, F.D.15
Zhang, H.S.16
Holmes, M.C.17
Zhang, L.18
Gregory, P.D.19
Rebar, E.J.20
more..
-
64
-
-
33847682924
-
Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases
-
COI: 1:CAS:528:DC%2BD2sXjtVWls74%3D, PID: 17360608
-
Moehle EA, Rock JM, Lee YL, Jouvenot Y, DeKelver RC, Gregory PD, Urnov FD, Holmes MC (2007) Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases. Proc Natl Acad Sci USA 104(9):3055–3060. doi:10.1073/pnas.0611478104
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.9
, pp. 3055-3060
-
-
Moehle, E.A.1
Rock, J.M.2
Lee, Y.L.3
Jouvenot, Y.4
DeKelver, R.C.5
Gregory, P.D.6
Urnov, F.D.7
Holmes, M.C.8
-
65
-
-
72149090954
-
A simple cipher governs DNA recognition by TAL effectors
-
COI: 1:CAS:528:DC%2BD1MXhsFensbjP, PID: 19933106
-
Moscou MJ, Bogdanove AJ (2009) A simple cipher governs DNA recognition by TAL effectors. Science 326(5959):1501. doi:10.1126/science.1178817
-
(2009)
Science
, vol.326
, Issue.5959
, pp. 1501
-
-
Moscou, M.J.1
Bogdanove, A.J.2
-
66
-
-
77955126358
-
Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology
-
PID: 20530528
-
Orlando SJ, Santiago Y, DeKelver RC, Freyvert Y, Boydston EA, Moehle EA, Choi VM, Gopalan SM, Lou JF, Li J, Miller JC, Holmes MC, Gregory PD, Urnov FD, Cost GJ (2010) Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology. Nucleic Acids Res 38(15):e152. doi:10.1093/nar/gkq512
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.15
, pp. e152
-
-
Orlando, S.J.1
Santiago, Y.2
DeKelver, R.C.3
Freyvert, Y.4
Boydston, E.A.5
Moehle, E.A.6
Choi, V.M.7
Gopalan, S.M.8
Lou, J.F.9
Li, J.10
Miller, J.C.11
Holmes, M.C.12
Gregory, P.D.13
Urnov, F.D.14
Cost, G.J.15
-
67
-
-
34047130851
-
I-Ssp6803I: the first homing endonuclease from the PD-(D/E)XK superfamily exhibits an unusual mode of DNA recognition
-
COI: 1:CAS:528:DC%2BD2sXkt1Ghsbg%3D, PID: 17242028
-
Orlowski J, Boniecki M, Bujnicki JM (2007) I-Ssp6803I: the first homing endonuclease from the PD-(D/E)XK superfamily exhibits an unusual mode of DNA recognition. Bioinformatics 23(5):527–530. doi:10.1093/bioinformatics/btm007
-
(2007)
Bioinformatics
, vol.23
, Issue.5
, pp. 527-530
-
-
Orlowski, J.1
Boniecki, M.2
Bujnicki, J.M.3
-
68
-
-
0034923498
-
Design and selection of novel Cys2His2 zinc finger proteins
-
COI: 1:CAS:528:DC%2BD3MXlsVeht7g%3D, PID: 11395410
-
Pabo CO, Peisach E, Grant RA (2001) Design and selection of novel Cys2His2 zinc finger proteins. Annu Rev Biochem 70:313–340. doi:10.1146/annurev.biochem.70.1.313
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 313-340
-
-
Pabo, C.O.1
Peisach, E.2
Grant, R.A.3
-
69
-
-
79958082248
-
Species-specific variation in RELA underlies differences in NF-κB activity: a potential role in African swine fever pathogenesis
-
COI: 1:CAS:528:DC%2BC3MXntFKqs78%3D, PID: 21450812
-
Palgrave CJ, Gilmour L, Lowden CS, Lillico SG, Mellencamp MA, Whitelaw CB (2011) Species-specific variation in RELA underlies differences in NF-κB activity: a potential role in African swine fever pathogenesis. J Virol 85(12):6008–6014. doi:10.1128/JVI.00331-11
-
(2011)
J Virol
, vol.85
, Issue.12
, pp. 6008-6014
-
-
Palgrave, C.J.1
Gilmour, L.2
Lowden, C.S.3
Lillico, S.G.4
Mellencamp, M.A.5
Whitelaw, C.B.6
-
70
-
-
0025773296
-
Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A
-
COI: 1:CAS:528:DyaK3MXisVeisbY%3D, PID: 2028256
-
Pavletich NP, Pabo CO (1991) Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A. Science 252(5007):809–817
-
(1991)
Science
, vol.252
, Issue.5007
, pp. 809-817
-
-
Pavletich, N.P.1
Pabo, C.O.2
-
71
-
-
51349092848
-
Development and validation of a highly efficient protocol of porcine somatic cloning using preovulatory embryo transfer in peripubertal gilts
-
COI: 1:CAS:528:DC%2BD1cXhtVOmu7%2FL, PID: 18729768
-
Petersen B, Lucas-Hahn A, Oropeza M, Hornen N, Lemme E, Hassel P, Queisser AL, Niemann H (2008) Development and validation of a highly efficient protocol of porcine somatic cloning using preovulatory embryo transfer in peripubertal gilts. Cloning Stem Cells 10(3):355–362. doi:10.1089/clo.2008.0026
-
(2008)
Cloning Stem Cells
, vol.10
, Issue.3
, pp. 355-362
-
-
Petersen, B.1
Lucas-Hahn, A.2
Oropeza, M.3
Hornen, N.4
Lemme, E.5
Hassel, P.6
Queisser, A.L.7
Niemann, H.8
-
72
-
-
0345504146
-
Markerless gene replacement in Escherichia coli stimulated by a double-strand break in the chromosome
-
COI: 1:CAS:528:DyaK1MXns1ykurY%3D, PID: 10536150
-
Posfai G, Kolisnychenko V, Bereczki Z, Blattner FR (1999) Markerless gene replacement in Escherichia coli stimulated by a double-strand break in the chromosome. Nucleic Acids Res 27(22):4409–4415
-
(1999)
Nucleic Acids Res
, vol.27
, Issue.22
, pp. 4409-4415
-
-
Posfai, G.1
Kolisnychenko, V.2
Bereczki, Z.3
Blattner, F.R.4
-
73
-
-
84919951002
-
Genome edited sheep and cattle
-
COI: 1:CAS:528:DC%2BC2cXhsFSgsLrF, PID: 25204701
-
Proudfoot C, Carlson DF, Huddart R, Long CR, Pryor JH, King TJ, Lillico SG, Mileham AJ, McLaren DG, Whitelaw CB, Fahrenkrug SC (2015) Genome edited sheep and cattle. Transgenic Res 24(1):147–153. doi:10.1007/s11248-014-9832-x
-
(2015)
Transgenic Res
, vol.24
, Issue.1
, pp. 147-153
-
-
Proudfoot, C.1
Carlson, D.F.2
Huddart, R.3
Long, C.R.4
Pryor, J.H.5
King, T.J.6
Lillico, S.G.7
Mileham, A.J.8
McLaren, D.G.9
Whitelaw, C.B.10
Fahrenkrug, S.C.11
-
74
-
-
0032618491
-
Use of I-Sce I to induce DNA double-strand breaks in Nicotiana
-
COI: 1:CAS:528:DyaK1MXkvFensbg%3D
-
Puchta H (1999) Use of I-Sce I to induce DNA double-strand breaks in Nicotiana. Methods Mol Biol (Clifton, NJ) 113:447–451. doi:10.1385/1-59259-675-4:447
-
(1999)
Methods Mol Biol (Clifton, NJ)
, vol.113
, pp. 447-451
-
-
Puchta, H.1
-
75
-
-
0036007685
-
Gene replacement by homologous recombination in plants
-
COI: 1:CAS:528:DC%2BD38Xht1Kqtro%3D, PID: 11860208
-
Puchta H (2002) Gene replacement by homologous recombination in plants. Plant Mol Biol 48(1–2):173–182
-
(2002)
Plant Mol Biol
, vol.48
, Issue.1-2
, pp. 173-182
-
-
Puchta, H.1
-
76
-
-
0020349256
-
Homologous pairing and strand exchange in genetic recombination
-
COI: 1:CAS:528:DyaL3sXkslOlsg%3D%3D, PID: 6297377
-
Radding CM (1982) Homologous pairing and strand exchange in genetic recombination. Annu Rev Genet 16:405–437. doi:10.1146/annurev.ge.16.120182.002201
-
(1982)
Annu Rev Genet
, vol.16
, pp. 405-437
-
-
Radding, C.M.1
-
77
-
-
76249113998
-
A muscle-specific transgenic reporter line of the sea anemone, Nematostella vectensis
-
COI: 1:CAS:528:DC%2BC3cXnsFCnsQ%3D%3D, PID: 20018670
-
Renfer E, Amon-Hassenzahl A, Steinmetz PR, Technau U (2010) A muscle-specific transgenic reporter line of the sea anemone, Nematostella vectensis. Proc Natl Acad Sci USA 107(1):104–108. doi:10.1073/pnas.0909148107
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.1
, pp. 104-108
-
-
Renfer, E.1
Amon-Hassenzahl, A.2
Steinmetz, P.R.3
Technau, U.4
-
78
-
-
52949154301
-
Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs
-
COI: 1:CAS:528:DC%2BD1cXhtFCrtLrP, PID: 18818360
-
Rogers CS, Stoltz DA, Meyerholz DK, Ostedgaard LS, Rokhlina T, Taft PJ, Rogan MP, Pezzulo AA, Karp PH, Itani OA, Kabel AC, Wohlford-Lenane CL, Davis GJ, Hanfland RA, Smith TL, Samuel M, Wax D, Murphy CN, Rieke A, Whitworth K, Uc A, Starner TD, Brogden KA, Shilyansky J, McCray PB Jr, Zabner J, Prather RS, Welsh MJ (2008) Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science 321(5897):1837–1841. doi:10.1126/science.1163600
-
(2008)
Science
, vol.321
, Issue.5897
, pp. 1837-1841
-
-
Rogers, C.S.1
Stoltz, D.A.2
Meyerholz, D.K.3
Ostedgaard, L.S.4
Rokhlina, T.5
Taft, P.J.6
Rogan, M.P.7
Pezzulo, A.A.8
Karp, P.H.9
Itani, O.A.10
Kabel, A.C.11
Wohlford-Lenane, C.L.12
Davis, G.J.13
Hanfland, R.A.14
Smith, T.L.15
Samuel, M.16
Wax, D.17
Murphy, C.N.18
Rieke, A.19
Whitworth, K.20
Uc, A.21
Starner, T.D.22
Brogden, K.A.23
Shilyansky, J.24
McCray, P.B.25
Zabner, J.26
Prather, R.S.27
Welsh, M.J.28
more..
-
79
-
-
33750209424
-
Homing endonuclease I-CreI derivatives with novel DNA target specificities
-
COI: 1:CAS:528:DC%2BD28XhtFeisb7L, PID: 16971456
-
Rosen LE, Morrison HA, Masri S, Brown MJ, Springstubb B, Sussman D, Stoddard BL, Seligman LM (2006) Homing endonuclease I-CreI derivatives with novel DNA target specificities. Nucleic Acids Res 34(17):4791–4800. doi:10.1093/nar/gkl645
-
(2006)
Nucleic Acids Res
, vol.34
, Issue.17
, pp. 4791-4800
-
-
Rosen, L.E.1
Morrison, H.A.2
Masri, S.3
Brown, M.J.4
Springstubb, B.5
Sussman, D.6
Stoddard, B.L.7
Seligman, L.M.8
-
80
-
-
0028237305
-
Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells
-
COI: 1:CAS:528:DyaK2cXkslCksL0%3D, PID: 8016116
-
Rouet P, Smih F, Jasin M (1994a) Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. Proc Natl Acad Sci USA 91(13):6064–6068
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.13
, pp. 6064-6068
-
-
Rouet, P.1
Smih, F.2
Jasin, M.3
-
81
-
-
0028061666
-
Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease
-
COI: 1:CAS:528:DyaK2MXisVWgtL4%3D, PID: 7969147
-
Rouet P, Smih F, Jasin M (1994b) Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol Cell Biol 14(12):8096–8106
-
(1994)
Mol Cell Biol
, vol.14
, Issue.12
, pp. 8096-8106
-
-
Rouet, P.1
Smih, F.2
Jasin, M.3
-
82
-
-
79961192836
-
Targeted gene disruption in somatic zebrafish cells using engineered TALENs
-
COI: 1:CAS:528:DC%2BC3MXpvVOlsrc%3D, PID: 21822241
-
Sander JD, Cade L, Khayter C, Reyon D, Peterson RT, Joung JK, Yeh JR (2011) Targeted gene disruption in somatic zebrafish cells using engineered TALENs. Nat Biotechnol 29(8):697–698. doi:10.1038/nbt.1934
-
(2011)
Nat Biotechnol
, vol.29
, Issue.8
, pp. 697-698
-
-
Sander, J.D.1
Cade, L.2
Khayter, C.3
Reyon, D.4
Peterson, R.T.5
Joung, J.K.6
Yeh, J.R.7
-
83
-
-
0036714153
-
Mutations altering the cleavage specificity of a homing endonuclease
-
COI: 1:CAS:528:DC%2BD38Xms1Klt7c%3D, PID: 12202772
-
Seligman LM, Chisholm KM, Chevalier BS, Chadsey MS, Edwards ST, Savage JH, Veillet AL (2002) Mutations altering the cleavage specificity of a homing endonuclease. Nucleic Acids Res 30(17):3870–3879
-
(2002)
Nucleic Acids Res
, vol.30
, Issue.17
, pp. 3870-3879
-
-
Seligman, L.M.1
Chisholm, K.M.2
Chevalier, B.S.3
Chadsey, M.S.4
Edwards, S.T.5
Savage, J.H.6
Veillet, A.L.7
-
84
-
-
84897954175
-
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
-
COI: 1:CAS:528:DC%2BC2cXjtlyls7g%3D, PID: 24584192
-
Shen B, Zhang W, Zhang J, Zhou J, Wang J, Chen L, Wang L, Hodgkins A, Iyer V, Huang X, Skarnes WC (2014) Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects. Nat Methods 11(4):399–402. doi:10.1038/nmeth.2857
-
(2014)
Nat Methods
, vol.11
, Issue.4
, pp. 399-402
-
-
Shen, B.1
Zhang, W.2
Zhang, J.3
Zhou, J.4
Wang, J.5
Chen, L.6
Wang, L.7
Hodgkins, A.8
Iyer, V.9
Huang, X.10
Skarnes, W.C.11
-
85
-
-
0036016441
-
Efficient repair of genomic double-strand breaks by homologous recombination between directly repeated sequences in the plant genome
-
COI: 1:CAS:528:DC%2BD38XksVGqtrg%3D, PID: 12034901
-
Siebert R, Puchta H (2002) Efficient repair of genomic double-strand breaks by homologous recombination between directly repeated sequences in the plant genome. Plant Cell 14(5):1121–1131
-
(2002)
Plant Cell
, vol.14
, Issue.5
, pp. 1121-1131
-
-
Siebert, R.1
Puchta, H.2
-
86
-
-
79951694132
-
Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy
-
COI: 1:CAS:528:DC%2BC3MXjtFaiu7s%3D, PID: 21182466
-
Silva G, Poirot L, Galetto R, Smith J, Montoya G, Duchateau P, Paques F (2011) Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy. Curr Gene Ther 11(1):11–27
-
(2011)
Curr Gene Ther
, vol.11
, Issue.1
, pp. 11-27
-
-
Silva, G.1
Poirot, L.2
Galetto, R.3
Smith, J.4
Montoya, G.5
Duchateau, P.6
Paques, F.7
-
87
-
-
0029598505
-
Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells
-
COI: 1:CAS:528:DyaK28XlsVCksQ%3D%3D, PID: 8559659
-
Smih F, Rouet P, Romanienko PJ, Jasin M (1995) Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells. Nucleic Acids Res 23(24):5012–5019
-
(1995)
Nucleic Acids Res
, vol.23
, Issue.24
, pp. 5012-5019
-
-
Smih, F.1
Rouet, P.2
Romanienko, P.J.3
Jasin, M.4
-
88
-
-
0034283804
-
Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains
-
COI: 1:CAS:528:DC%2BD3cXmvVSntrc%3D, PID: 10954606
-
Smith J, Bibikova M, Whitby FG, Reddy AR, Chandrasegaran S, Carroll D (2000) Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains. Nucleic Acids Res 28(17):3361–3369
-
(2000)
Nucleic Acids Res
, vol.28
, Issue.17
, pp. 3361-3369
-
-
Smith, J.1
Bibikova, M.2
Whitby, F.G.3
Reddy, A.R.4
Chandrasegaran, S.5
Carroll, D.6
-
89
-
-
33845914020
-
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences
-
PID: 17130168
-
Smith J, Grizot S, Arnould S, Duclert A, Epinat JC, Chames P, Prieto J, Redondo P, Blanco FJ, Bravo J, Montoya G, Paques F, Duchateau P (2006) A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences. Nucleic Acids Res 34(22):e149. doi:10.1093/nar/gkl720
-
(2006)
Nucleic Acids Res
, vol.34
, Issue.22
, pp. e149
-
-
Smith, J.1
Grizot, S.2
Arnould, S.3
Duclert, A.4
Epinat, J.C.5
Chames, P.6
Prieto, J.7
Redondo, P.8
Blanco, F.J.9
Bravo, J.10
Montoya, G.11
Paques, F.12
Duchateau, P.13
-
90
-
-
4143097044
-
Isolation and characterization of new homing endonuclease specificities at individual target site positions
-
COI: 1:CAS:528:DC%2BD2cXmslegsL0%3D, PID: 15313605
-
Sussman D, Chadsey M, Fauce S, Engel A, Bruett A, Monnat R Jr, Stoddard BL, Seligman LM (2004) Isolation and characterization of new homing endonuclease specificities at individual target site positions. J Mol Biol 342(1):31–41. doi:10.1016/j.jmb.2004.07.031
-
(2004)
J Mol Biol
, vol.342
, Issue.1
, pp. 31-41
-
-
Sussman, D.1
Chadsey, M.2
Fauce, S.3
Engel, A.4
Bruett, A.5
Monnat, R.6
Stoddard, B.L.7
Seligman, L.M.8
-
91
-
-
34447323568
-
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BD2sXnsFaru74%3D, PID: 17603476
-
Szczepek M, Brondani V, Buchel J, Serrano L, Segal DJ, Cathomen T (2007) Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. Nat Biotechnol 25(7):786–793. doi:10.1038/nbt1317
-
(2007)
Nat Biotechnol
, vol.25
, Issue.7
, pp. 786-793
-
-
Szczepek, M.1
Brondani, V.2
Buchel, J.3
Serrano, L.4
Segal, D.J.5
Cathomen, T.6
-
92
-
-
34249035232
-
In vivo construction of transgenes in Drosophila
-
COI: 1:CAS:528:DC%2BD2sXmsFylsbs%3D, PID: 17179096
-
Takeuchi H, Georgiev O, Fetchko M, Kappeler M, Schaffner W, Egli D (2007) In vivo construction of transgenes in Drosophila. Genetics 175(4):2019–2028. doi:10.1534/genetics.106.065920
-
(2007)
Genetics
, vol.175
, Issue.4
, pp. 2019-2028
-
-
Takeuchi, H.1
Georgiev, O.2
Fetchko, M.3
Kappeler, M.4
Schaffner, W.5
Egli, D.6
-
93
-
-
84885358161
-
Efficient nonmeiotic allele introgression in livestock using custom endonucleases
-
COI: 1:CAS:528:DC%2BC3sXhs1Kju7%2FL, PID: 24014591
-
Tan W, Carlson DF, Lancto CA, Garbe JR, Webster DA, Hackett PB, Fahrenkrug SC (2013) Efficient nonmeiotic allele introgression in livestock using custom endonucleases. Proc Natl Acad Sci USA 110(41):16526–16531. doi:10.1073/pnas.1310478110
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.41
, pp. 16526-16531
-
-
Tan, W.1
Carlson, D.F.2
Lancto, C.A.3
Garbe, J.R.4
Webster, D.A.5
Hackett, P.B.6
Fahrenkrug, S.C.7
-
94
-
-
79959319829
-
CRISPR-based adaptive immune systems
-
COI: 1:CAS:528:DC%2BC3MXns12kurs%3D, PID: 21531607
-
Terns MP, Terns RM (2011) CRISPR-based adaptive immune systems. Curr Opin Microbiol 14(3):321–327. doi:10.1016/j.mib.2011.03.005
-
(2011)
Curr Opin Microbiol
, vol.14
, Issue.3
, pp. 321-327
-
-
Terns, M.P.1
Terns, R.M.2
-
95
-
-
79961196358
-
Knockout rats generated by embryo microinjection of TALENs
-
COI: 1:CAS:528:DC%2BC3MXpvVOlurY%3D, PID: 21822240
-
Tesson L, Usal C, Menoret S, Leung E, Niles BJ, Remy S, Santiago Y, Vincent AI, Meng X, Zhang L, Gregory PD, Anegon I, Cost GJ (2011) Knockout rats generated by embryo microinjection of TALENs. Nat Biotechnol 29(8):695–696. doi:10.1038/nbt.1940
-
(2011)
Nat Biotechnol
, vol.29
, Issue.8
, pp. 695-696
-
-
Tesson, L.1
Usal, C.2
Menoret, S.3
Leung, E.4
Niles, B.J.5
Remy, S.6
Santiago, Y.7
Vincent, A.I.8
Meng, X.9
Zhang, L.10
Gregory, P.D.11
Anegon, I.12
Cost, G.J.13
-
96
-
-
84902204289
-
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
-
COI: 1:CAS:528:DC%2BC2cXmvV2ntbk%3D, PID: 24770325
-
Tsai SQ, Wyvekens N, Khayter C, Foden JA, Thapar V, Reyon D, Goodwin MJ, Aryee MJ, Joung JK (2014) Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing. Nat Biotechnol 32(6):569–576. doi:10.1038/nbt.2908
-
(2014)
Nat Biotechnol
, vol.32
, Issue.6
, pp. 569-576
-
-
Tsai, S.Q.1
Wyvekens, N.2
Khayter, C.3
Foden, J.A.4
Thapar, V.5
Reyon, D.6
Goodwin, M.J.7
Aryee, M.J.8
Joung, J.K.9
-
97
-
-
18944373328
-
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BD2MXks1OgtLk%3D, PID: 15806097
-
Urnov FD, Miller JC, Lee YL, Beausejour CM, Rock JM, Augustus S, Jamieson AC, Porteus MH, Gregory PD, Holmes MC (2005) Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 435(7042):646–651. doi:10.1038/nature03556
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 646-651
-
-
Urnov, F.D.1
Miller, J.C.2
Lee, Y.L.3
Beausejour, C.M.4
Rock, J.M.5
Augustus, S.6
Jamieson, A.C.7
Porteus, M.H.8
Gregory, P.D.9
Holmes, M.C.10
-
98
-
-
84255167154
-
Coronary microvascular dysfunction in a porcine model of early atherosclerosis and diabetes
-
PID: 21984550
-
van den Heuvel M, Sorop O, Koopmans SJ, Dekker R, de Vries R, van Beusekom HM, Eringa EC, Duncker DJ, Danser AH, van der Giessen WJ (2012) Coronary microvascular dysfunction in a porcine model of early atherosclerosis and diabetes. Am J Physiol Heart Circ Physiol 302(1):H85–H94. doi:10.1152/ajpheart.00311.2011
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
, Issue.1
, pp. H85-H94
-
-
van den Heuvel, M.1
Sorop, O.2
Koopmans, S.J.3
Dekker, R.4
de Vries, R.5
van Beusekom, H.M.6
Eringa, E.C.7
Duncker, D.J.8
Danser, A.H.9
van der Giessen, W.J.10
-
99
-
-
0035902445
-
Manipulating the mammalian genome by homologous recombination
-
COI: 1:CAS:528:DC%2BD3MXls1Wis7o%3D, PID: 11459982
-
Vasquez KM, Marburger K, Intody Z, Wilson JH (2001) Manipulating the mammalian genome by homologous recombination. Proc Natl Acad Sci USA 98(15):8403–8410. doi:10.1073/pnas.111009698
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.15
, pp. 8403-8410
-
-
Vasquez, K.M.1
Marburger, K.2
Intody, Z.3
Wilson, J.H.4
-
100
-
-
72149111192
-
Plant science. DNA binding made easy
-
COI: 1:CAS:528:DC%2BD1MXhsFyit7%2FO, PID: 20007890
-
Voytas DF, Joung JK (2009) Plant science. DNA binding made easy. Science 326(5959):1491–1492. doi:10.1126/science.1183604
-
(2009)
Science
, vol.326
, Issue.5959
, pp. 1491-1492
-
-
Voytas, D.F.1
Joung, J.K.2
-
101
-
-
84861984839
-
Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme
-
PID: 22434427
-
Wang J, Friedman G, Doyon Y, Wang NS, Li CJ, Miller JC, Hua KL, Yan JJ, Babiarz JE, Gregory PD, Holmes MC (2012) Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme. Genome Res 22(7):1316–1326. doi:10.1101/gr.122879.111
-
(2012)
Genome Res
, vol.22
, Issue.7
, pp. 1316-1326
-
-
Wang, J.1
Friedman, G.2
Doyon, Y.3
Wang, N.S.4
Li, C.J.5
Miller, J.C.6
Hua, K.L.7
Yan, J.J.8
Babiarz, J.E.9
Gregory, P.D.10
Holmes, M.C.11
-
102
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
COI: 1:CAS:528:DC%2BC3sXmvF2nt7w%3D, PID: 23643243
-
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R (2013) One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153(4):910–918. doi:10.1016/j.cell.2013.04.025
-
(2013)
Cell
, vol.153
, Issue.4
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
103
-
-
78049251841
-
Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases
-
COI: 1:CAS:528:DC%2BC3cXhtlKrsLfK, PID: 20875794
-
Watanabe M, Umeyama K, Matsunari H, Takayanagi S, Haruyama E, Nakano K, Fujiwara T, Ikezawa Y, Nakauchi H, Nagashima H (2010) Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases. Biochem Biophys Res Commun 402(1):14–18
-
(2010)
Biochem Biophys Res Commun
, vol.402
, Issue.1
, pp. 14-18
-
-
Watanabe, M.1
Umeyama, K.2
Matsunari, H.3
Takayanagi, S.4
Haruyama, E.5
Nakano, K.6
Fujiwara, T.7
Ikezawa, Y.8
Nakauchi, H.9
Nagashima, H.10
-
104
-
-
84885151931
-
Generation of interleukin-2 receptor gamma gene knockout pigs from somatic cells genetically modified by zinc finger nuclease-encoding mRNA
-
COI: 1:CAS:528:DC%2BC3sXhs1egs7%2FK, PID: 24130776
-
Watanabe M, Nakano K, Matsunari H, Matsuda T, Maehara M, Kanai T, Kobayashi M, Matsumura Y, Sakai R, Kuramoto M, Hayashida G, Asano Y, Takayanagi S, Arai Y, Umeyama K, Nagaya M, Hanazono Y, Nagashima H (2013) Generation of interleukin-2 receptor gamma gene knockout pigs from somatic cells genetically modified by zinc finger nuclease-encoding mRNA. PLoS ONE 8(10):e76478. doi:10.1371/journal.pone.0076478
-
(2013)
PLoS ONE
, vol.8
, Issue.10
, pp. e76478
-
-
Watanabe, M.1
Nakano, K.2
Matsunari, H.3
Matsuda, T.4
Maehara, M.5
Kanai, T.6
Kobayashi, M.7
Matsumura, Y.8
Sakai, R.9
Kuramoto, M.10
Hayashida, G.11
Asano, Y.12
Takayanagi, S.13
Arai, Y.14
Umeyama, K.15
Nagaya, M.16
Hanazono, Y.17
Nagashima, H.18
-
105
-
-
84921602939
-
Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos
-
PID: 25100712
-
Whitworth KM, Lee K, Benne JA, Beaton BP, Spate LD, Murphy SL, Samuel MS, Mao J, O’Gorman C, Walters EM, Murphy CN, Driver J, Mileham A, McLaren D, Wells KD, Prather RS (2014a) Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos. Biol Reprod 91(3):78. doi:10.1095/biolreprod.114.121723
-
(2014)
Biol Reprod
, vol.91
, Issue.3
, pp. 78
-
-
Whitworth, K.M.1
Lee, K.2
Benne, J.A.3
Beaton, B.P.4
Spate, L.D.5
Murphy, S.L.6
Samuel, M.S.7
Mao, J.8
O’Gorman, C.9
Walters, E.M.10
Murphy, C.N.11
Driver, J.12
Mileham, A.13
McLaren, D.14
Wells, K.D.15
Prather, R.S.16
-
106
-
-
84921602939
-
Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos
-
PID: 25100712
-
Whitworth KM, Lee K, Benne JA, Beaton BP, Spate LD, Murphy SL, Samuel MS, Mao J, O’Gorman C, Walters EM, Murphy CN, Driver JP, Mileham A, McLaren D, Wells KD, Prather RS (2014b) Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos. Biol Reprod. doi:10.1095/biolreprod.114.121723
-
(2014)
Biol Reprod
-
-
Whitworth, K.M.1
Lee, K.2
Benne, J.A.3
Beaton, B.P.4
Spate, L.D.5
Murphy, S.L.6
Samuel, M.S.7
Mao, J.8
O’Gorman, C.9
Walters, E.M.10
Murphy, C.N.11
Driver, J.P.12
Mileham, A.13
McLaren, D.14
Wells, K.D.15
Prather, R.S.16
-
107
-
-
84858052771
-
Zinc finger nucleases to create custom-designed modifications in the swine (Sus scrofa) genome
-
PID: 22038991
-
Whyte JJ, Prather RS (2011) Zinc finger nucleases to create custom-designed modifications in the swine (Sus scrofa) genome. J Anim Sci. doi:10.2527/jas.2011-4546
-
(2011)
J Anim Sci
-
-
Whyte, J.J.1
Prather, R.S.2
-
108
-
-
79251529218
-
Gene targeting with zinc finger nucleases to produce cloned eGFP knockout pigs
-
COI: 1:CAS:528:DC%2BC3MXpvV2lsw%3D%3D, PID: 21268178
-
Whyte JJ, Zhao J, Wells KD, Samuel MS, Whitworth KM, Walters EM, Laughlin MH, Prather RS (2011) Gene targeting with zinc finger nucleases to produce cloned eGFP knockout pigs. Mol Reprod Dev 78(1):2. doi:10.1002/mrd.21271
-
(2011)
Mol Reprod Dev
, vol.78
, Issue.1
, pp. 2
-
-
Whyte, J.J.1
Zhao, J.2
Wells, K.D.3
Samuel, M.S.4
Whitworth, K.M.5
Walters, E.M.6
Laughlin, M.H.7
Prather, R.S.8
-
109
-
-
84857097177
-
RNA-guided genetic silencing systems in bacteria and archaea
-
COI: 1:CAS:528:DC%2BC38Xit12jur4%3D, PID: 22337052
-
Wiedenheft B, Sternberg SH, Doudna JA (2012) RNA-guided genetic silencing systems in bacteria and archaea. Nature 482(7385):331–338. doi:10.1038/nature10886
-
(2012)
Nature
, vol.482
, Issue.7385
, pp. 331-338
-
-
Wiedenheft, B.1
Sternberg, S.H.2
Doudna, J.A.3
-
110
-
-
34848885878
-
Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos
-
COI: 1:CAS:528:DC%2BD2sXhtFWiu7fP, PID: 17726053
-
Windbichler N, Papathanos PA, Catteruccia F, Ranson H, Burt A, Crisanti A (2007) Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos. Nucleic Acids Res 35(17):5922–5933. doi:10.1093/nar/gkm632
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.17
, pp. 5922-5933
-
-
Windbichler, N.1
Papathanos, P.A.2
Catteruccia, F.3
Ranson, H.4
Burt, A.5
Crisanti, A.6
-
111
-
-
85027921901
-
Generation of PPARgamma mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning
-
Yang D, Yang H, Li W, Zhao B, Ouyang Z, Liu Z, Zhao Y, Fan N, Song J, Tian J, Li F, Zhang J, Chang L, Pei D, Chen YE, Lai L (2011) Generation of PPARgamma mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning. Cell Res. doi:10.1038/cr.2011.70
-
(2011)
Cell Res
-
-
Yang, D.1
Yang, H.2
Li, W.3
Zhao, B.4
Ouyang, Z.5
Liu, Z.6
Zhao, Y.7
Fan, N.8
Song, J.9
Tian, J.10
Li, F.11
Zhang, J.12
Chang, L.13
Pei, D.14
Chen, Y.E.15
Lai, L.16
-
112
-
-
84884289608
-
One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering
-
COI: 1:CAS:528:DC%2BC3sXhtlGqtr%2FN, PID: 23992847
-
Yang H, Wang H, Shivalila CS, Cheng AW, Shi L, Jaenisch R (2013) One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering. Cell 154(6):1370–1379. doi:10.1016/j.cell.2013.08.022
-
(2013)
Cell
, vol.154
, Issue.6
, pp. 1370-1379
-
-
Yang, H.1
Wang, H.2
Shivalila, C.S.3
Cheng, A.W.4
Shi, L.5
Jaenisch, R.6
-
113
-
-
49249139249
-
Rapid and efficient construction of markerless deletions in the Escherichia coli genome
-
PID: 18567910
-
Yu BJ, Kang KH, Lee JH, Sung BH, Kim MS, Kim SC (2008) Rapid and efficient construction of markerless deletions in the Escherichia coli genome. Nucleic Acids Res 36(14):e84. doi:10.1093/nar/gkn359
-
(2008)
Nucleic Acids Res
, vol.36
, Issue.14
, pp. e84
-
-
Yu, B.J.1
Kang, K.H.2
Lee, J.H.3
Sung, B.H.4
Kim, M.S.5
Kim, S.C.6
-
114
-
-
80555150663
-
Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle
-
COI: 1:CAS:528:DC%2BC3MXhsVags7%2FF, PID: 21912434
-
Yu S, Luo J, Song Z, Ding F, Dai Y, Li N (2011) Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle. Cell Res 21(11):1638–1640. doi:10.1038/cr.2011.153
-
(2011)
Cell Res
, vol.21
, Issue.11
, pp. 1638-1640
-
-
Yu, S.1
Luo, J.2
Song, Z.3
Ding, F.4
Dai, Y.5
Li, N.6
|