Targeted transgene insertion into the AAVS1 locus driven by baculoviral vector-mediated zinc finger nuclease expression in human-induced pluripotent stem cells

Journal of Gene Medicine

Volumn 15, Issue 10, 2013, Pages 384-395

  Tay, Felix Chang ^a   Tan, Wee Kiat ^a   Goh, Sal Lee ^a   Ramachandra, Chrishan J A ^a,b   Lau, Cia Hin ^a   Zhu, Haibao ^a   Chen, Can ^a   Du, Shouhui ^a   Phang, Rui Zhe ^a   Shahbazi, Mohammad ^a,b   Fan, Weimin ^c   Wang, Shu ^a,b,c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Baculoviral transduction; Cassette exchange; Homologous recombination; IPS cells; Zinc finger nuclease

Indexed keywords

BACULOVIRUS VECTOR; CRE RECOMBINASE; ENHANCED GREEN FLUORESCENT PROTEIN; PROTEIN; PROTEIN AAVS1; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE;

AAVS1 GENE; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; DNA TEMPLATE; EMBRYO; EMBRYOID BODY; GENE; GENE CASSETTE; GENE INSERTION; GENE LOCUS; GENE TARGETING; HUMAN; HUMAN CELL; LOXP SITE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOUTHERN BLOTTING; TRANSGENE;

BACULOVIRAL TRANSDUCTION; CASSETTE EXCHANGE; HOMOLOGOUS RECOMBINATION; IPS CELLS; ZINC FINGER NUCLEASE;

BACULOVIRIDAE; ENDONUCLEASES; GENE EXPRESSION; GENE ORDER; GENES, REPORTER; GENETIC LOCI; GENETIC VECTORS; HOMOLOGOUS RECOMBINATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MUTAGENESIS, INSERTIONAL; TRANSGENES; ZINC FINGERS;

EID: 84885920900     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.2745     Document Type: Article

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