-
1
-
-
33747816812
-
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
-
Mandell JG, BarbasIII CF: Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases. Nucleic Acids Res 2006, 34: W516-523. 10.1093/nar/gkl209
-
(2006)
Nucleic Acids Res
, vol.34
, pp. W516-W523
-
-
Mandell, J.G.1
Barbas, C.F.2
-
2
-
-
84934438162
-
TAL Effector Nuclease (TALEN) Engineering
-
Li T, Yang B: TAL Effector Nuclease (TALEN) Engineering. Methods Mol Biol 2013, 978: 63-72. 10.1007/978-1-62703-293-3_5
-
(2013)
Methods Mol Biol
, vol.978
, pp. 63-72
-
-
Li, T.1
Yang, B.2
-
3
-
-
78951479577
-
Targeting DNA double-strand breaks with TAL effector nucleases
-
Christian M, Cermak T, Doyle EL, Schmidt C, Zhang F, Hummel A, Bogdanove AJ, Voytas DF: Targeting DNA double-strand breaks with TAL effector nucleases. Genetics 2010, 186: 757-761. 10.1534/genetics.110.120717
-
(2010)
Genetics
, vol.186
, pp. 757-761
-
-
Christian, M.1
Cermak, T.2
Doyle, E.L.3
Schmidt, C.4
Zhang, F.5
Hummel, A.6
Bogdanove, A.J.7
Voytas, D.F.8
-
4
-
-
79960095536
-
Concise review: putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells
-
Collin J, Lako M: Concise review: putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells. Stem Cells 2011, 29: 1021-1033. 10.1002/stem.658
-
(2011)
Stem Cells
, vol.29
, pp. 1021-1033
-
-
Collin, J.1
Lako, M.2
-
5
-
-
67649170378
-
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells
-
Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L: Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell 2009, 5: 97-110. 10.1016/j.stem.2009.05.023
-
(2009)
Cell Stem Cell
, vol.5
, pp. 97-110
-
-
Zou, J.1
Maeder, M.L.2
Mali, P.3
Pruett-Miller, S.M.4
Thibodeau-Beganny, S.5
Chou, B.K.6
Chen, G.7
Ye, Z.8
Park, I.H.9
Daley, G.Q.10
Porteus, M.H.11
Joung, J.K.12
Cheng, L.13
-
6
-
-
79960836456
-
Genetic engineering of human pluripotent cells using TALE nucleases
-
Hockemeyer D, Wang HY, Kiani S, Lai CS, Gao Q, Cassady JP, Cost GJ, Zhang L, Santiago Y, Miller JC, Zeitler B, Cherone JM, Meng XD, Hinkley SJ, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R: Genetic engineering of human pluripotent cells using TALE nucleases. Nat Biotechnol 2011, 29: 731-734. 10.1038/nbt.1927
-
(2011)
Nat Biotechnol
, vol.29
, pp. 731-734
-
-
Hockemeyer, D.1
Wang, H.Y.2
Kiani, S.3
Lai, C.S.4
Gao, Q.5
Cassady, J.P.6
Cost, G.J.7
Zhang, L.8
Santiago, Y.9
Miller, J.C.10
Zeitler, B.11
Cherone, J.M.12
Meng, X.D.13
Hinkley, S.J.14
Rebar, E.J.15
Gregory, P.D.16
Urnov, F.D.17
Jaenisch, R.18
-
7
-
-
84873733109
-
A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models
-
Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, Schinzel RT, Xia F, Tang A, Xia Y, Figueroa E, Wann A, Ahfeldt T, Daheron L, Zhang F, Rubin LL, Peng LF, Chung RT, Musunuru K, Cowan CA: A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models. Cell Stem Cell 2013, 12: 238-251. 10.1016/j.stem.2012.11.011
-
(2013)
Cell Stem Cell
, vol.12
, pp. 238-251
-
-
Ding, Q.1
Lee, Y.K.2
Schaefer, E.A.3
Peters, D.T.4
Veres, A.5
Kim, K.6
Kuperwasser, N.7
Motola, D.L.8
Meissner, T.B.9
Hendriks, W.T.10
Trevisan, M.11
Gupta, R.M.12
Moisan, A.13
Banks, E.14
Friesen, M.15
Schinzel, R.T.16
Xia, F.17
Tang, A.18
Xia, Y.19
Figueroa, E.20
Wann, A.21
Ahfeldt, T.22
Daheron, L.23
Zhang, F.24
Rubin, L.L.25
Peng, L.F.26
Chung, R.T.27
Musunuru, K.28
Cowan, C.A.29
more..
-
8
-
-
0038745599
-
Progress and problems with the use of viral vectors for gene therapy
-
Thomas CE, Ehrhardt A, Kay MA: Progress and problems with the use of viral vectors for gene therapy. Nat Rev Genet 2003, 4: 346-358. 10.1038/nrg1066
-
(2003)
Nat Rev Genet
, vol.4
, pp. 346-358
-
-
Thomas, C.E.1
Ehrhardt, A.2
Kay, M.A.3
-
9
-
-
42049095153
-
Cell-penetrating peptides: from molecular mechanisms to therapeutics
-
Morris MC, Deshayes S, Heitz F, Divita G: Cell-penetrating peptides: from molecular mechanisms to therapeutics. Biol Cell 2008, 100: 201-217. 10.1042/BC20070116
-
(2008)
Biol Cell
, vol.100
, pp. 201-217
-
-
Morris, M.C.1
Deshayes, S.2
Heitz, F.3
Divita, G.4
-
10
-
-
41149118540
-
TAT opens the door
-
Vyas PM, Payne RM: TAT opens the door. Mol Ther 2008, 16: 647-648. 10.1038/mt.2008.24
-
(2008)
Mol Ther
, vol.16
, pp. 647-648
-
-
Vyas, P.M.1
Payne, R.M.2
-
11
-
-
77958150472
-
Happy birthday cell penetrating peptides: already 20 years
-
Brasseur R, Divita G: Happy birthday cell penetrating peptides: already 20 years. Biochim Biophys Acta 2010, 1798: 2177-2181. 10.1016/j.bbamem.2010.09.001
-
(2010)
Biochim Biophys Acta
, vol.1798
, pp. 2177-2181
-
-
Brasseur, R.1
Divita, G.2
-
12
-
-
79952074339
-
CCR5: From Natural Resistance to a New Anti-HIV Strategy
-
Lopalco L: CCR5: From Natural Resistance to a New Anti-HIV Strategy. Viruses 2010, 2: 574-600. 10.3390/v2020574
-
(2010)
Viruses
, vol.2
, pp. 574-600
-
-
Lopalco, L.1
-
13
-
-
60549090253
-
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
-
Hutter G, Nowak D, Mossner M, Ganepola S, Mussig A, Allers K, Schneider T, Hofmann J, Kucherer C, Blau O, Blau IW, Hofmann WK, Thiel E: Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med 2009, 360: 692-698. 10.1056/NEJMoa0802905
-
(2009)
N Engl J Med
, vol.360
, pp. 692-698
-
-
Hutter, G.1
Nowak, D.2
Mossner, M.3
Ganepola, S.4
Mussig, A.5
Allers, K.6
Schneider, T.7
Hofmann, J.8
Kucherer, C.9
Blau, O.10
Blau, I.W.11
Hofmann, W.K.12
Thiel, E.13
-
14
-
-
79953117041
-
Evidence for the cure of HIV infection by CCR5Delta32/Delta32 stem cell transplantation
-
Allers K, Hutter G, Hofmann J, Loddenkemper C, Rieger K, Thiel E, Schneider T: Evidence for the cure of HIV infection by CCR5Delta32/Delta32 stem cell transplantation. Blood 2011, 117: 2791-2799. 10.1182/blood-2010-09-309591
-
(2011)
Blood
, vol.117
, pp. 2791-2799
-
-
Allers, K.1
Hutter, G.2
Hofmann, J.3
Loddenkemper, C.4
Rieger, K.5
Thiel, E.6
Schneider, T.7
-
15
-
-
46949095221
-
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
-
Perez EE, Wang J, Miller JC, Jouvenot Y, Kim KA, Liu O, Wang N, Lee G, Bartsevich VV, Lee YL, Guschin DY, Rupniewski I, Waite AJ, Carpenito C, Carroll RG, Orange JS, Urnov FD, Rebar EJ, Ando D, Gregory PD, Riley JL, Holmes MC, June CH: Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. Nat Biotechnol 2008, 26: 808-816. 10.1038/nbt1410
-
(2008)
Nat Biotechnol
, vol.26
, pp. 808-816
-
-
Perez, E.E.1
Wang, J.2
Miller, J.C.3
Jouvenot, Y.4
Kim, K.A.5
Liu, O.6
Wang, N.7
Lee, G.8
Bartsevich, V.V.9
Lee, Y.L.10
Guschin, D.Y.11
Rupniewski, I.12
Waite, A.J.13
Carpenito, C.14
Carroll, R.G.15
Orange, J.S.16
Urnov, F.D.17
Rebar, E.J.18
Ando, D.19
Gregory, P.D.20
Riley, J.L.21
Holmes, M.C.22
June, C.H.23
more..
-
16
-
-
78650735673
-
Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo
-
Holt N, Wang J, Kim K, Friedman G, Wang X, Taupin V, Crooks GM, Kohn DB, Gregory PD, Holmes MC, Cannon PM: Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo. Nat Biotechnol 2010, 28: 839-847. 10.1038/nbt.1663
-
(2010)
Nat Biotechnol
, vol.28
, pp. 839-847
-
-
Holt, N.1
Wang, J.2
Kim, K.3
Friedman, G.4
Wang, X.5
Taupin, V.6
Crooks, G.M.7
Kohn, D.B.8
Gregory, P.D.9
Holmes, M.C.10
Cannon, P.M.11
-
17
-
-
78549290274
-
The use of cell-delivered gene therapy for the treatment of HIV/AIDS
-
Symonds GP, Johnstone HA, Millington ML, Boyd MP, Burke BP, Breton LR: The use of cell-delivered gene therapy for the treatment of HIV/AIDS. Immunol Res 2010, 48: 84-98. 10.1007/s12026-010-8169-7
-
(2010)
Immunol Res
, vol.48
, pp. 84-98
-
-
Symonds, G.P.1
Johnstone, H.A.2
Millington, M.L.3
Boyd, M.P.4
Burke, B.P.5
Breton, L.R.6
-
18
-
-
79954617023
-
HIV: HIV hides in haematopoietic stem cells
-
Huddleston JE: HIV: HIV hides in haematopoietic stem cells. Nat Rev Microbiol 2011, 9: 311. 10.1038/nrmicro2564
-
(2011)
Nat Rev Microbiol
, vol.9
, pp. 311
-
-
Huddleston, J.E.1
-
19
-
-
84863116293
-
Generation of CD34+ Cells from CCR5-disrupted Human Embryonic and Induced Pluripotent Stem Cells
-
Yao Y, Nashun B, Zhou T, Qin L, Zhao S, Xu J, Esteban MA, Chen X: Generation of CD34+ Cells from CCR5-disrupted Human Embryonic and Induced Pluripotent Stem Cells. Hum Gene Ther 2011, 23: 238-242.
-
(2011)
Hum Gene Ther
, vol.23
, pp. 238-242
-
-
Yao, Y.1
Nashun, B.2
Zhou, T.3
Qin, L.4
Zhao, S.5
Xu, J.6
Esteban, M.A.7
Chen, X.8
-
20
-
-
11144356610
-
Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation
-
Wang Z, Troilo PJ, Wang X, Griffiths TG, Pacchione SJ, Barnum AB, Harper LB, Pauley CJ, Niu Z, Denisova L, Follmer TT, Rizzuto G, Ciliberto G, Fattori E, Monica NL, Manam S, Ledwith BJ: Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation. Gene Ther 2004, 11: 711-721. 10.1038/sj.gt.3302213
-
(2004)
Gene Ther
, vol.11
, pp. 711-721
-
-
Wang, Z.1
Troilo, P.J.2
Wang, X.3
Griffiths, T.G.4
Pacchione, S.J.5
Barnum, A.B.6
Harper, L.B.7
Pauley, C.J.8
Niu, Z.9
Denisova, L.10
Follmer, T.T.11
Rizzuto, G.12
Ciliberto, G.13
Fattori, E.14
Monica, N.L.15
Manam, S.16
Ledwith, B.J.17
-
21
-
-
78149470105
-
A novel concept in antiangiogenic and antitumoral therapy: multitarget destabilization of short-lived mRNAs by the zinc finger protein ZFP36L1
-
Planel S, Salomon A, Jalinot P, Feige JJ, Cherradi N: A novel concept in antiangiogenic and antitumoral therapy: multitarget destabilization of short-lived mRNAs by the zinc finger protein ZFP36L1. Oncogene 2010, 29: 5989-6003. 10.1038/onc.2010.341
-
(2010)
Oncogene
, vol.29
, pp. 5989-6003
-
-
Planel, S.1
Salomon, A.2
Jalinot, P.3
Feige, J.J.4
Cherradi, N.5
-
22
-
-
77956561675
-
CPP-ZFN: a potential DNA-targeting anti-malarial drug
-
Nain V, Sahi S, Verma A: CPP-ZFN: a potential DNA-targeting anti-malarial drug. Malar J 2010, 9: 258. 10.1186/1475-2875-9-258
-
(2010)
Malar J
, vol.9
, pp. 258
-
-
Nain, V.1
Sahi, S.2
Verma, A.3
-
23
-
-
84864439768
-
Targeted gene knockout by direct delivery of zinc-finger nuclease proteins
-
Gaj T, Guo J, Kato Y, Sirk SJ, Barbas III CF: Targeted gene knockout by direct delivery of zinc-finger nuclease proteins. Nat Methods 2012, 9: 805-807. 10.1038/nmeth.2030
-
(2012)
Nat Methods
, vol.9
, pp. 805-807
-
-
Gaj, T.1
Guo, J.2
Kato, Y.3
Sirk, S.J.4
Barbas, C.F.5
-
24
-
-
84875298381
-
A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly
-
Chen S, Oikonomou G, Chiu CN, Niles BJ, Liu J, Lee DA, Antoshechkin I, Prober DA: A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly. Nucleic Acids Res 2013, 41: 2769-2778. 10.1093/nar/gks1356
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 2769-2778
-
-
Chen, S.1
Oikonomou, G.2
Chiu, C.N.3
Niles, B.J.4
Liu, J.5
Lee, D.A.6
Antoshechkin, I.7
Prober, D.A.8
-
25
-
-
84861348512
-
Efficient and specific modifications of the Drosophila genome by means of an easy TALEN strategy
-
Liu J, Li C, Yu Z, Huang P, Wu H, Wei C, Zhu N, Shen Y, Chen Y, Zhang B, Deng WM, Jiao R: Efficient and specific modifications of the Drosophila genome by means of an easy TALEN strategy. J Genet Genomics 2012, 39: 209-215. 10.1016/j.jgg.2012.04.003
-
(2012)
J Genet Genomics
, vol.39
, pp. 209-215
-
-
Liu, J.1
Li, C.2
Yu, Z.3
Huang, P.4
Wu, H.5
Wei, C.6
Zhu, N.7
Shen, Y.8
Chen, Y.9
Zhang, B.10
Deng, W.M.11
Jiao, R.12
-
26
-
-
79960064013
-
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
-
Cermak T, Doyle EL, Christian M, Wang L, Zhang Y, Schmidt C, Baller JA, Somia NV, Bogdanove AJ, Voytas DF: Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Res 2011, 39: e82. 10.1093/nar/gkr218
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Cermak, T.1
Doyle, E.L.2
Christian, M.3
Wang, L.4
Zhang, Y.5
Schmidt, C.6
Baller, J.A.7
Somia, N.V.8
Bogdanove, A.J.9
Voytas, D.F.10
-
27
-
-
84860747716
-
FLASH assembly of TALENs for high-throughput genome editing
-
Reyon D, Tsai SQ, Khayter C, Foden JA, Sander JD, Joung JK: FLASH assembly of TALENs for high-throughput genome editing. Nat Biotechnol 2012, 30: 460-465. 10.1038/nbt.2170
-
(2012)
Nat Biotechnol
, vol.30
, pp. 460-465
-
-
Reyon, D.1
Tsai, S.Q.2
Khayter, C.3
Foden, J.A.4
Sander, J.D.5
Joung, J.K.6
-
28
-
-
77953023690
-
Transient cold shock enhances zinc-finger nuclease-mediated gene disruption
-
Doyon Y, Choi VM, Xia DF, Vo TD, Gregory PD, Holmes MC: Transient cold shock enhances zinc-finger nuclease-mediated gene disruption. Nat Methods 2010, 7: 459-460. 10.1038/nmeth.1456
-
(2010)
Nat Methods
, vol.7
, pp. 459-460
-
-
Doyon, Y.1
Choi, V.M.2
Xia, D.F.3
Vo, T.D.4
Gregory, P.D.5
Holmes, M.C.6
-
29
-
-
79551685675
-
A TALE nuclease architecture for efficient genome editing
-
Miller JC, Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, Zhang HS, Holmes MC, Zhang L, Gregory PD, Rebar EJ: A TALE nuclease architecture for efficient genome editing. Nat Biotechnol 2011, 29: 143-148. 10.1038/nbt.1755
-
(2011)
Nat Biotechnol
, vol.29
, pp. 143-148
-
-
Miller, J.C.1
Tan, S.2
Qiao, G.3
Barlow, K.A.4
Wang, J.5
Xia, D.F.6
Meng, X.7
Paschon, D.E.8
Leung, E.9
Hinkley, S.J.10
Dulay, G.P.11
Hua, K.L.12
Ankoudinova, I.13
Cost, G.J.14
Urnov, F.D.15
Zhang, H.S.16
Holmes, M.C.17
Zhang, L.18
Gregory, P.D.19
Rebar, E.J.20
more..
-
30
-
-
59149103100
-
A toolbox and procedural notes for characterizing novel zinc finger nucleases for genome editing in plant cells
-
Tovkach A, Zeevi V, Tzfira T: A toolbox and procedural notes for characterizing novel zinc finger nucleases for genome editing in plant cells. Plant J 2009, 57: 747-757. 10.1111/j.1365-313X.2008.03718.x
-
(2009)
Plant J
, vol.57
, pp. 747-757
-
-
Tovkach, A.1
Zeevi, V.2
Tzfira, T.3
-
31
-
-
77957754251
-
A rapid and general assay for monitoring endogenous gene modification
-
Guschin DY, Waite AJ, Katibah GE, Miller JC, Holmes MC, Rebar EJ: A rapid and general assay for monitoring endogenous gene modification. Methods Mol Biol 2010, 649: 247-256. 10.1007/978-1-60761-753-2_15
-
(2010)
Methods Mol Biol
, vol.649
, pp. 247-256
-
-
Guschin, D.Y.1
Waite, A.J.2
Katibah, G.E.3
Miller, J.C.4
Holmes, M.C.5
Rebar, E.J.6
|