Utilization of the AAVS1 safe harbor locus for hematopoietic specific transgene expression and gene knockdown in human ES cells

Stem Cell Research

Volumn 12, Issue 3, 2014, Pages 630-637

  Tiyaboonchai, Amita ^a,b   Mac, Helen ^b   Shamsedeen, Razveen ^b   Mills, Jason A ^b   Kishore, Siddarth ^b   French, Deborah L ^b   Gadue, Paul ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; LEUKOSIALIN; MICRORNA; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR PU 1; ZINC FINGER NUCLEASE; HYBRID PROTEIN;

AAVS1 LOCUS; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ERYTHROID CELL; GENE EXPRESSION; GENE INSERTION; GENE LOCUS; GENE REPRESSION; GENE SILENCING; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENE; TRANSGENE EXPRESSION; CYTOLOGY; DEVICES; EVALUATION STUDY; GENE TARGETING; GENE VECTOR; GENETIC RECOMBINATION; GENETICS; HEMATOPOIETIC STEM CELL; METABOLISM; PLURIPOTENT STEM CELL; PROCEDURES; REPORTER GENE;

ANTIGENS, CD43; EMBRYONIC STEM CELLS; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GENE TARGETING; GENES, REPORTER; GENETIC LOCI; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HEMATOPOIETIC STEM CELLS; HUMANS; PLURIPOTENT STEM CELLS; RECOMBINANT FUSION PROTEINS; RECOMBINATION, GENETIC; TRANSGENES;

EID: 84896033634     PISSN: 18735061     EISSN: 18767753     Source Type: Journal    
DOI: 10.1016/j.scr.2014.02.004     Document Type: Article

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