Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

Biochemistry

Volumn 42, Issue 7, 2003, Pages 2137-2148

  Segal, David J ^a,b   Beerli, Roger R ^c   Blancafort, Pilar ^a   Dreier, Birgit ^d   Effertz, Karin ^a   Huber, Adrian ^a   Koksch, Beate ^e   Lund, Caren V ^a   Magnenat, Laurent ^a   Valente, David ^a   Barbas III, Carlos F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c CYTOS BIOTECHNOLOGY AG   (Switzerland)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DNA; GENES; ZINC;

PROTEIN LENGTH;

PROTEINS;

DNA BINDING PROTEIN; ZINC FINGER PROTEIN;

ARTICLE; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE TARGETING; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN SYNTHESIS;

DNA; DNA-BINDING PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; OLIGONUCLEOTIDES; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; REPETITIVE SEQUENCES, AMINO ACID; TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 0344839044     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026806o     Document Type: Article

References (49)

1. Beerli, R. R., and Barbas, C. F., III (2002) Nat. Biotech. 20, 135-141.
2. Segal, D., and Barbas, C. F., III (2001) Curr. Opin. Biotech. 12, 632-637.
3. Segal, D. J., and Barbas, C. F., III (2000) Curr. Opin. Chem. Biol. 4, 34-39.
4. Beerli, R. R., Dreier, B., and Barbas, C. F., III (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 1495-1500.
5. Liu, P. Q., Rebar, E. J., Zhang, L., Liu, Q., Jamieson, A. C., Liang, Y., Qi, H., Li, P. X., Chen, B., and Mendel, M. C., et al. (2001) J. Biol. Chem. 276, 11323-11334.
6. Zhang, L., Spratt, S. K., Liu, Q., Johnstone, B., Qi, H., Raschke, E. E., Jamieson, A. C., Rebar, E. J., Wolffe, A. P., and Case, C. C. (2000) J. Biol. Chem. 275, 33850-33860.
7. Guan, X., Stege, J., Kim, M., Dahmani, Z., Fan, N., Heifetz, P., Barbas, C. F., III, and Briggs, S. P. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 13296-13301.
8. Ordiz, M. I., Barbas, C. F., III, and Beachy, R. N. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 13290-13295.
9. Xu, L., Zerby, D., Huang, Y., Ji, H., Nyanguile, O. F., de los Angeles, J. E., and Kadan, M. J. (2001) Mol. Ther. 3, 262-273.
10. Bibikova, M., Golic, M., Golic, K. G., and Carroll, D. (2002) Genetics 161, 1169-75.
11. Holmes-Son, M. L., Appa, R. S., and Chow, S. A. (2001) Adv. Genet. 43, 33-69.
12. Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) Science 291, 1304-1351.
13. Pabo, C. O., and Nekludova, L. (2000) J. Mol. Biol. 301, 597-624.
14. Elrod-Erickson, M., Rould, M. A., Nekludova, L., and Pabo, C. O. (1996) Structure 4, 1171-1180.
15. Pavletich, N. P., and Pabo, C. O. (1991) Science 252, 809-817.
16. Narayan, V. A., Kriwacki, R. W., and Caradonna, J. P. (1997) J. Biol. Chem. 272, 7801-7809.
17. Dreier, B., Beerli, R. R., Segal, D. J., Flippin, J. D., and Barbas III, C. F. (2001) J. Biol. Chem. 276, 29466-29478.
18. Dreier, B., Segal, D. J., and Barbas, C. F., III (2000) J. Mol. Biol. 303, 489-502.
19. Segal, D. J., Dreier, B., Beerli, R. R., and Barbas, C. F., III (1999) Proc. Natl. Acad. Sci. U S A 96, 2758-2763.
20. Beerli, R. R., Segal, D. J., Dreier, B., and Barbas, C. F., III (1998) Proc. Natl. Acad. Sci. U S A 95, 14628-14633.
21. Liu, Q., Segal, D. J., Ghiara, J. B., and Barbas, C. F., III (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 5525-5530.
22. Desjarlais, J. R., and Berg, J. M. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 2256-2260.
23. Isalan, M., Choo, Y., and Klug, A. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 5617-5621.
24. Jamieson, A. C., Wang, H., and Kim, S.-H. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 12834-12839.
25. Wolfe, S. A., Grant, R. A., Elrod-Erickson, M., and Pabo, C. O. (2001) Struture 9, 717-723.
26. Pabo, C. O., Peisach, E., and Grant, R. A. (2001) Annu. Rev. Biochem. 70, 313-340.
27. Wuttke, D. S., Foster, M. P., Case, D. A., Gottesfeld, J. M., and Wright, P. E. (1997) J. Mol. Biol. 273, 183-206.
28. Jamieson, A. C., Kim, S.-H., and Wells, J. A. (1994) Biochemistry 33, 5689-5695.
29. Isalan, M., Klug, A., and Choo, Y. (2001) Nat. Biotechnol. 19, 656-660.
30. Greisman, H. A., and Pabo, C. O. (1997) Science 275, 657-661.
31. Wright, W. E., Binder, M., and Funk, W. (1991) Mol. Cell. Biol. 11, 4104-4110.
32. Swirnoff, A. H., and Milbrandt, J. (1995) Mol. Cell. Biol. 15, 2275-2287.
33. Thiesen, H. J., and Bach, C. (1990) Nucleic Acids Res. 18, 3203-3209.
34. Shi, Y., and Berg, J. M. (1995) Chem. Biol. 2, 83-89.
35. Nagaoka, N., Shiraishi, Y., and Sugiura, Y. (2001) Nucleic Acids Res. 29, 4920-4929.
36. Corbi, N., Libri, V., Fanciulli, M., and Passananti, C. (1998) Biochem. Biophys. Res. Commun. 253, 686-692.
37. Corbi, N., Perez, M., Maione, R., and Passananti, C. (1997) FEBS Lett. 417, 71-74.
38. Desjarlais, J. R., and Berg, J. M. (1992) Proteins: Struct., Funct., Genet. 12, 101-104.
39. Wolfe, S. A., Greisman, H. A., Ramm, E. I., and Pabo, C. O. (1999) J. Mol. Biol. 285, 1917-1934.
40. Liu, Q., Xia, Z., Zhong, X., and Case, C. C. (2002) J. Biol. Chem. 277, 3850-3856.
41. Corbi, N., Libri, V., Fanciulli, M., Tinsley, J. M., Davies, K. E., and Passananti, C. (2000) Gene Ther. 7, 1076-1083.
42. Choo, Y. (1998) Nucleic Acids Res. 26, 554-557.
43. Kim, C. A., and Berg, J. M. (1995) J. Mol. Biol. 252, 1-5.
44. Nagaoka, M., Shiraishi, Y., Uno, Y., Nomura, W., and Sugiura, Y. (2002) Biochemistry 41, 8819-8825.
45. Laity, J. H., Dyson, H. J., and Wright, P. E. (2000) J. Mol. Biol. 295, 719-727.
46. Kim, C. A., and Berg, J. M. (1996) Nat. Struct. Biol. 3, 940-945.
47. Kim, J. S., and Pabo, C. O. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 2812-2817.
48. Moore, M., Klug, A., and Choo, Y. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 1437-1441.
49. Nagaoka, M., Nomura, W., Shiraishi, Y., and Sugiura, Y. (2001) Biochem. Biophys. Res. Commun. 282, 1001-1007.