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Volumn 7, Issue 4, 2015, Pages 1578-1598

Eradication of HIV-1 from the macrophage reservoir: An uncertain goal?

Author keywords

CART; HIV 1; Latency; Macrophage; Reservoirs

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

EID: 84928952324     PISSN: 19994915     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v7041578     Document Type: Review
Times cited : (74)

References (158)
  • 1
    • 84904438190 scopus 로고    scopus 로고
    • HIV infection: Epidemiology, pathogenesis, treatment, and prevention
    • Maartens, G.; Celum, C.; Lewin, S.R. HIV infection: Epidemiology, pathogenesis, treatment, and prevention. Lancet 2014, 384, 258-271.
    • (2014) Lancet , vol.384 , pp. 258-271
    • Maartens, G.1    Celum, C.2    Lewin, S.R.3
  • 2
    • 84886782112 scopus 로고    scopus 로고
    • An integrated overview of HIV-1 latency
    • Ruelas, D.S.; Greene, W.C. An integrated overview of HIV-1 latency. Cell 2013, 155, 519-529.
    • (2013) Cell , vol.155 , pp. 519-529
    • Ruelas, D.S.1    Greene, W.C.2
  • 6
    • 84907348191 scopus 로고    scopus 로고
    • Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013
    • Murray, C.J.; Ortblad, K.F.; Guinovart, C.; Lim, S.S.; Wolock, T.M.; Roberts, D.A.; Dansereau, E.A.; Graetz, N.; Barber, R.M.; Brown, J.C., et al. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet 2014, 384, 1005-1070.
    • (2014) Lancet , vol.384 , pp. 1005-1070
    • Murray, C.J.1    Ortblad, K.F.2    Guinovart, C.3    Lim, S.S.4    Wolock, T.M.5    Roberts, D.A.6    Dansereau, E.A.7    Graetz, N.8    Barber, R.M.9    Brown, J.C.10
  • 7
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators
    • Palella, F.J., Jr.; Delaney, K.M.; Moorman, A.C.; Loveless, M.O.; Fuhrer, J.; Satten, G.A.; Aschman, D.J.; Holmberg, S.D. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N. Engl. J. Med. 1998, 338, 853-860.
    • (1998) N. Engl. J. Med , vol.338 , pp. 853-860
    • Palella, F.J.1    Delaney, K.M.2    Moorman, A.C.3    Loveless, M.O.4    Fuhrer, J.5    Satten, G.A.6    Aschman, D.J.7    Holmberg, S.D.8
  • 8
    • 84897965706 scopus 로고    scopus 로고
    • Cure research: Advances and prospects
    • Passaes, C.P.; Saez-Cirion, A. HIV cure research: Advances and prospects. Virology 2014, 454, 340-352.
    • (2014) Virology , vol.454 , pp. 340-352
    • Passaes, C.P.1    Saez-Cirion, A.2
  • 11
    • 84905570028 scopus 로고    scopus 로고
    • HIV: Early treatment may not be early enough
    • Deng, K.; Siliciano, R.F. HIV: Early treatment may not be early enough. Nature 2014, 512, 35-36.
    • (2014) Nature , vol.512 , pp. 35-36
    • Deng, K.1    Siliciano, R.F.2
  • 14
    • 84891827613 scopus 로고    scopus 로고
    • Emerging strategies to deplete the HIV reservoir
    • Archin, N.M.; Margolis, D.M. Emerging strategies to deplete the HIV reservoir. Curr. Opin. Infect. Dis. 2014, 27, 29-35.
    • (2014) Curr. Opin. Infect. Dis , vol.27 , pp. 29-35
    • Archin, N.M.1    Margolis, D.M.2
  • 15
    • 84879437402 scopus 로고    scopus 로고
    • HIV-1 transcription and latency: An update
    • Van Lint, C.; Bouchat, S.; Marcello, A. HIV-1 transcription and latency: An update. Retrovirology 2013, 10, e67.
    • (2013) Retrovirology , vol.10 , pp. 67
    • Van Lint, C.1    Bouchat, S.2    Marcello, A.3
  • 16
    • 70350148394 scopus 로고    scopus 로고
    • Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs
    • Coiras, M.; Lopez-Huertas, M.R.; Perez-Olmeda, M.; Alcami, J. Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs. Nat. Rev. Microbiol. 2009, 7, 798-812.
    • (2009) Nat. Rev. Microbiol , vol.7 , pp. 798-812
    • Coiras, M.1    Lopez-Huertas, M.R.2    Perez-Olmeda, M.3    Alcami, J.4
  • 17
    • 84886790685 scopus 로고    scopus 로고
    • The end of AIDS: HIV infection as a chronic disease
    • Deeks, S.G.; Lewin, S.R.; Havlir, D.V. The end of AIDS: HIV infection as a chronic disease. Lancet 2013, 382, 1525-1533.
    • (2013) Lancet , vol.382 , pp. 1525-1533
    • Deeks, S.G.1    Lewin, S.R.2    Havlir, D.V.3
  • 18
    • 84897440149 scopus 로고    scopus 로고
    • Long-lived reservoirs of HIV-1
    • Zaikos, T.D.; Collins, K.L. Long-lived reservoirs of HIV-1. Trends Microbiol. 2014, 22, 173-175.
    • (2014) Trends Microbiol , vol.22 , pp. 173-175
    • Zaikos, T.D.1    Collins, K.L.2
  • 19
    • 84918502862 scopus 로고    scopus 로고
    • Changes in HIV reservoirs during long-term antiretroviral therapy
    • Hong, F.F.; Mellors, J.W. Changes in HIV reservoirs during long-term antiretroviral therapy. Curr. Opin. HIV AIDS 2015, 10, 43-48.
    • (2015) Curr. Opin. HIV AIDS , vol.10 , pp. 43-48
    • Hong, F.F.1    Mellors, J.W.2
  • 21
    • 53849134844 scopus 로고    scopus 로고
    • Cellular reservoirs of HIV-1 and their role in viral persistence
    • Alexaki, A.; Liu, Y.; Wigdahl, B. Cellular reservoirs of HIV-1 and their role in viral persistence. Curr. HIV Res. 2008, 6, 388-400.
    • (2008) Curr. HIV Res , vol.6 , pp. 388-400
    • Alexaki, A.1    Liu, Y.2    Wigdahl, B.3
  • 22
    • 84918595374 scopus 로고    scopus 로고
    • How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs
    • Ananworanich, J.; Dube, K.; Chomont, N. How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs? Curr. Opin. HIV AIDS 2015, 10, 18-28.
    • (2015) Curr. Opin. HIV AIDS , vol.10 , pp. 18-28
    • Ananworanich, J.1    Dube, K.2    Chomont, N.3
  • 23
    • 84873825163 scopus 로고    scopus 로고
    • Molecular understanding of HIV-1 latency
    • Abbas, W.; Herbein, G. Molecular understanding of HIV-1 latency. Adv. Virol. 2012, 9, e574967.
    • (2012) Adv. Virol , vol.9
    • Abbas, W.1    Herbein, G.2
  • 24
    • 84902967486 scopus 로고    scopus 로고
    • Opening fronts in HIV vaccine development: Targeting reservoirs to clear and cure
    • Siliciano, R.F. Opening fronts in HIV vaccine development: Targeting reservoirs to clear and cure. Nat. Med. 2014, 20, 480-481.
    • (2014) Nat. Med , vol.20 , pp. 480-481
    • Siliciano, R.F.1
  • 25
    • 73249136755 scopus 로고    scopus 로고
    • Molecular control of HIV-1 postintegration latency: Implications for the development of new therapeutic strategies
    • Colin, L.; van Lint, C. Molecular control of HIV-1 postintegration latency: Implications for the development of new therapeutic strategies. Retrovirology 2009, 6, e111.
    • (2009) Retrovirology , vol.6
    • Colin, L.1    Van Lint, C.2
  • 26
    • 84899154430 scopus 로고    scopus 로고
    • HIV-1 latency in monocytes/macrophages
    • Kumar, A.; Abbas, W.; Herbein, G. HIV-1 latency in monocytes/macrophages. Viruses 2014, 6, 1837-1860.
    • (2014) Viruses , vol.6 , pp. 1837-1860
    • Kumar, A.1    Abbas, W.2    Herbein, G.3
  • 27
    • 33644540503 scopus 로고    scopus 로고
    • Latency: The hidden HIV-1 challenge
    • Marcello, A. Latency: The hidden HIV-1 challenge. Retrovirology 2006, 3, e7.
    • (2006) Retrovirology , vol.3
    • Marcello, A.1
  • 29
    • 0025008853 scopus 로고
    • High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients
    • Pang, S.; Koyanagi, Y.; Miles, S.; Wiley, C.; Vinters, H.V.; Chen, I.S. High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients. Nature 1990, 343, 85-89.
    • (1990) Nature , vol.343 , pp. 85-89
    • Pang, S.1    Koyanagi, Y.2    Miles, S.3    Wiley, C.4    Vinters, H.V.5    Chen, I.S.6
  • 30
    • 39449110192 scopus 로고    scopus 로고
    • Human macrophages support persistent transcription from unintegrated HIV-1 DNA
    • Kelly, J.; Beddall, M.H.; Yu, D.; Iyer, S.R.; Marsh, J.W.; Wu, Y. Human macrophages support persistent transcription from unintegrated HIV-1 DNA. Virology 2008, 372, 300-312.
    • (2008) Virology , vol.372 , pp. 300-312
    • Kelly, J.1    Beddall, M.H.2    Yu, D.3    Iyer, S.R.4    Marsh, J.W.5    Wu, Y.6
  • 31
    • 77249123298 scopus 로고    scopus 로고
    • Mechanisms of HIV latency: An emerging picture of complexity
    • Margolis, D.M. Mechanisms of HIV latency: An emerging picture of complexity. Curr. HIV/ AIDS Rep. 2010, 7, 37-43.
    • (2010) Curr. HIV/ AIDS Rep , vol.7 , pp. 37-43
    • Margolis, D.M.1
  • 34
    • 84885057631 scopus 로고    scopus 로고
    • Non-coding RNAs: Novel players in chromatin-regulation during viral latency
    • Eilebrecht, S.; Schwartz, C.; Rohr, O. Non-coding RNAs: Novel players in chromatin-regulation during viral latency. Curr. Opin. Virol. 2013, 3, 387-393.
    • (2013) Curr. Opin. Virol , vol.3 , pp. 387-393
    • Eilebrecht, S.1    Schwartz, C.2    Rohr, O.3
  • 35
    • 84856476640 scopus 로고    scopus 로고
    • Mechanisms of HIV-1 latency post HAART treatment area
    • Al-Harthi, L.; Kashanchi, F. Mechanisms of HIV-1 latency post HAART treatment area. Curr. HIV Res. 2011, 9, 552-553.
    • (2011) Curr. HIV Res , vol.9 , pp. 552-553
    • Al-Harthi, L.1    Kashanchi, F.2
  • 37
    • 77950676781 scopus 로고    scopus 로고
    • Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage
    • Le Douce, V.; Herbein, G.; Rohr, O.; Schwartz, C. Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage. Retrovirology 2010, 7, e32.
    • (2010) Retrovirology , vol.7 , pp. 32
    • Le Douce, V.1    Herbein, G.2    Rohr, O.3    Schwartz, C.4
  • 38
    • 0347320927 scopus 로고    scopus 로고
    • Macrophage HIV-1 infection and the gastrointestinal tract reservoir
    • Smith, P.D.; Meng, G.; Salazar-Gonzalez, J.F.; Shaw, G.M. Macrophage HIV-1 infection and the gastrointestinal tract reservoir. J. Leukoc. Biol. 2003, 74, 642-649.
    • (2003) J. Leukoc. Biol , vol.74 , pp. 642-649
    • Smith, P.D.1    Meng, G.2    Salazar-Gonzalez, J.F.3    Shaw, G.M.4
  • 41
    • 84893829335 scopus 로고    scopus 로고
    • TNF and TNF receptor superfamily members in HIV infection: New cellular targets for therapy?
    • Kumar, A.; Abbas, W.; Herbein, G. TNF and TNF receptor superfamily members in HIV infection: New cellular targets for therapy? Mediators Inflamm. 2013, 2013, e484378.
    • (2013) Mediators Inflamm , vol.2013
    • Kumar, A.1    Abbas, W.2    Herbein, G.3
  • 42
    • 84927734923 scopus 로고    scopus 로고
    • The importance of monocytes and macrophages in HIV pathogenesis, treatment, and cure
    • Campbell, J.H.; Hearps, A.C.; Martin, G.E.; Williams, K.C.; Crowe, S.M. The importance of monocytes and macrophages in HIV pathogenesis, treatment, and cure. AIDS 2014, 28, 2175-2187.
    • (2014) AIDS , vol.28 , pp. 2175-2187
    • Campbell, J.H.1    Hearps, A.C.2    Martin, G.E.3    Williams, K.C.4    Crowe, S.M.5
  • 44
    • 84928948602 scopus 로고    scopus 로고
    • The macrophage: A therapeutic target in HIV-1 infection
    • Kumar, A.; Herbein, G. The macrophage: A therapeutic target in HIV-1 infection. Mol. Cell. Ther. 2014, 2, e10.
    • (2014) Mol. Cell. Ther , vol.2
    • Kumar, A.1    Herbein, G.2
  • 45
    • 0036138852 scopus 로고    scopus 로고
    • Evidence for human immunodeficiency virus type 1 replication in vivo in CD14+ monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy
    • Zhu, T.; Muthui, D.; Holte, S.; Nickle, D.; Feng, F.; Brodie, S.; Hwangbo, Y.; Mullins, J.I.; Corey, L. Evidence for human immunodeficiency virus type 1 replication in vivo in CD14+ monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy. J. Virol. 2002, 76, 707-716.
    • (2002) J. Virol , vol.76 , pp. 707-716
    • Zhu, T.1    Muthui, D.2    Holte, S.3    Nickle, D.4    Feng, F.5    Brodie, S.6    Hwangbo, Y.7    Mullins, J.I.8    Corey, L.9
  • 46
    • 0034144463 scopus 로고    scopus 로고
    • Detection of infectious HIV in circulating monocytes from patients on prolonged highly active antiretroviral therapy
    • Lambotte, O.; Taoufik, Y.; de Goer, M.G.; Wallon, C.; Goujard, C.; Delfraissy, J.F. Detection of infectious HIV in circulating monocytes from patients on prolonged highly active antiretroviral therapy. J. Acquir. Immune Defic. Syndr. 2000, 23, 114-119.
    • (2000) J. Acquir. Immune Defic. Syndr , vol.23 , pp. 114-119
    • Lambotte, O.1    Taoufik, Y.2    De Goer, M.G.3    Wallon, C.4    Goujard, C.5    Delfraissy, J.F.6
  • 47
    • 0026064198 scopus 로고
    • Latent HIV-1 infection in enriched populations of blood monocytes and T cells from seropositive patients
    • McElrath, M.J.; Steinman, R.M.; Cohn, Z.A. Latent HIV-1 infection in enriched populations of blood monocytes and T cells from seropositive patients. J. Clin. Invest. 1991, 87, 27-30.
    • (1991) J. Clin. Invest , vol.87 , pp. 27-30
    • McElrath, M.J.1    Steinman, R.M.2    Cohn, Z.A.3
  • 48
    • 33646184547 scopus 로고    scopus 로고
    • HAART-persistent HIV-1 latent reservoirs: Their origin, mechanisms of stability and potential strategies for eradication
    • Kulkosky, J.; Bray, S. HAART-persistent HIV-1 latent reservoirs: Their origin, mechanisms of stability and potential strategies for eradication. Curr. HIV Res.2006, 4, 199-208.
    • (2006) Curr. HIV Res , vol.4 , pp. 199-208
    • Kulkosky, J.1    Bray, S.2
  • 49
    • 84928958835 scopus 로고    scopus 로고
    • Healthy HIV-1-infected individuals on highly active antiretroviral therapy harbor HIV-1 in their alveolar macrophages
    • Cribbs, S.K.; Lennox, J.; Caliendo, A.M.; Brown, L.A.; Guidot, D.M. Healthy HIV-1-infected individuals on highly active antiretroviral therapy harbor HIV-1 in their alveolar macrophages. AIDS Res. Hum. Retrovirus. 2015, 31, 64-70.
    • (2015) AIDS Res. Hum. Retrovirus , vol.31 , pp. 64-70
    • Cribbs, S.K.1    Lennox, J.2    Caliendo, A.M.3    Brown, L.A.4    Guidot, D.M.5
  • 50
    • 0029414974 scopus 로고
    • CD14lowCD16high: A cytokine-producing monocyte subset which expands during human immunodeficiency virus infection
    • Thieblemont, N.; Weiss, L.; Sadeghi, H.M.; Estcourt, C.; Haeffner-Cavaillon, N. CD14lowCD16high: A cytokine-producing monocyte subset which expands during human immunodeficiency virus infection. Eur. J. Immunol. 1995, 25, 3418-3424.
    • (1995) Eur. J. Immunol , vol.25 , pp. 3418-3424
    • Thieblemont, N.1    Weiss, L.2    Sadeghi, H.M.3    Estcourt, C.4    Haeffner-Cavaillon, N.5
  • 51
    • 0035808518 scopus 로고    scopus 로고
    • Monocytes harbour replication-competent non-latent HIV-1 in patients on highly active antiretroviral therapy
    • Sonza, S.; Mutimer, H.P.; Oelrichs, R.; Jardine, D.; Harvey, K.; Dunne, A.; Purcell, D.F.; Birch, C.; Crowe, S.M. Monocytes harbour replication-competent non-latent HIV-1 in patients on highly active antiretroviral therapy. AIDS 2001, 15, 17-22.
    • (2001) AIDS , vol.15 , pp. 17-22
    • Sonza, S.1    Mutimer, H.P.2    Oelrichs, R.3    Jardine, D.4    Harvey, K.5    Dunne, A.6    Purcell, D.F.7    Birch, C.8    Crowe, S.M.9
  • 54
    • 77950588818 scopus 로고    scopus 로고
    • Editorial: Monocyte subpopulations and lentiviral infection
    • Crowe, S.M.; Ziegler-Heitbrock, L. Editorial: Monocyte subpopulations and lentiviral infection. J. Leukoc. Biol. 2010, 87, 541-543.
    • (2010) J. Leukoc. Biol , vol.87 , pp. 541-543
    • Crowe, S.M.1    Ziegler-Heitbrock, L.2
  • 55
    • 84876452768 scopus 로고    scopus 로고
    • Selective expansion of pro-inflammatory chemokine CCL2-loaded CD14+CD16+ monocytes subset in HIV-infected therapy naive individuals
    • Ansari, A.W.; Meyer-Olson, D.; Schmidt, R.E. Selective expansion of pro-inflammatory chemokine CCL2-loaded CD14+CD16+ monocytes subset in HIV-infected therapy naive individuals. J. Clin. Immunol. 2013, 33, 302-306.
    • (2013) J. Clin. Immunol , vol.33 , pp. 302-306
    • Ansari, A.W.1    Meyer-Olson, D.2    Schmidt, R.E.3
  • 56
    • 82255186886 scopus 로고    scopus 로고
    • CCL2: A potential prognostic marker and target of anti-inflammatory strategy in HIV/AIDS pathogenesis
    • Ansari, A.W.; Heiken, H.; Meyer-Olson, D.; Schmidt, R.E. CCL2: A potential prognostic marker and target of anti-inflammatory strategy in HIV/AIDS pathogenesis. Eur. J. Immunol. 2011, 41, 3412-3418.
    • (2011) Eur. J. Immunol , vol.41 , pp. 3412-3418
    • Ansari, A.W.1    Heiken, H.2    Meyer-Olson, D.3    Schmidt, R.E.4
  • 57
    • 15144361055 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication
    • Cinque, P.; Vago, L.; Mengozzi, M.; Torri, V.; Ceresa, D.; Vicenzi, E.; Transidico, P.; Vagani, A.; Sozzani, S.; Mantovani, A., et al. Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication. AIDS 1998, 12, 1327-1332.
    • (1998) AIDS , vol.12 , pp. 1327-1332
    • Cinque, P.1    Vago, L.2    Mengozzi, M.3    Torri, V.4    Ceresa, D.5    Vicenzi, E.6    Transidico, P.7    Vagani, A.8    Sozzani, S.9    Mantovani, A.10
  • 58
    • 0033638895 scopus 로고    scopus 로고
    • Divergent regulation of HIV-1 replication in PBMC of infected individuals by CC chemokines: Suppression by RANTES, MIP-1alpha, and MCP-3, and enhancement by MCP-1
    • Vicenzi, E.; Alfano, M.; Ghezzi, S.; Gatti, A.; Veglia, F.; Lazzarin, A.; Sozzani, S.; Mantovani, A.; Poli, G. Divergent regulation of HIV-1 replication in PBMC of infected individuals by CC chemokines: Suppression by RANTES, MIP-1alpha, and MCP-3, and enhancement by MCP-1. J. Leukoc. Biol. 2000, 68, 405-412.
    • (2000) J. Leukoc. Biol , vol.68 , pp. 405-412
    • Vicenzi, E.1    Alfano, M.2    Ghezzi, S.3    Gatti, A.4    Veglia, F.5    Lazzarin, A.6    Sozzani, S.7    Mantovani, A.8    Poli, G.9
  • 59
    • 70349436101 scopus 로고    scopus 로고
    • Determination of hepatitis C virus-infected monocyte lineage reservoirs in individuals with or without HIV coinfection
    • Coquillard, G.; Patterson, B.K. Determination of hepatitis C virus-infected monocyte lineage reservoirs in individuals with or without HIV coinfection. J. Infect. Dis. 2009, 200, 947-954.
    • (2009) J. Infect. Dis , vol.200 , pp. 947-954
    • Coquillard, G.1    Patterson, B.K.2
  • 60
    • 84900993010 scopus 로고    scopus 로고
    • Cellular activation and intracellular HCV load in peripheral blood monocytes isolated from HCV monoinfected and HIV-HCV coinfected patients
    • Dichamp, I.; Abbas, W.; Kumar, A.; di Martino, V.; Herbein, G. Cellular activation and intracellular HCV load in peripheral blood monocytes isolated from HCV monoinfected and HIV-HCV coinfected patients. PLOS ONE 2014, 9, e96907.
    • (2014) PLOS ONE , vol.9
    • Dichamp, I.1    Abbas, W.2    Kumar, A.3    Di Martino, V.4    Herbein, G.5
  • 61
    • 84908653357 scopus 로고    scopus 로고
    • M1 and M2 macrophages: The chicken and the egg of immunity
    • Mills, C.D.; Ley, K. M1 and M2 macrophages: The chicken and the egg of immunity. J. Innate Immun. 2014, 6, 716-726.
    • (2014) J. Innate Immun , vol.6 , pp. 716-726
    • Mills, C.D.1    Ley, K.2
  • 62
    • 84925283886 scopus 로고    scopus 로고
    • The chemotaxis of M1 and M2 macrophages is regulated by different chemokines
    • Xuan, W.; Qu, Q.; Zheng, B.; Xiong, S.; Fan, G.H. The chemotaxis of M1 and M2 macrophages is regulated by different chemokines. J. Leukoc. Biol. 2015, 97, 61-69.
    • (2015) J. Leukoc. Biol , vol.97 , pp. 61-69
    • Xuan, W.1    Qu, Q.2    Zheng, B.3    Xiong, S.4    Fan, G.H.5
  • 64
    • 77950659445 scopus 로고    scopus 로고
    • The macrophage in HIV-1 infection: From activation to deactivation?
    • Herbein, G.; Varin, A. The macrophage in HIV-1 infection: From activation to deactivation? Retrovirology 2010, 7, e33.
    • (2010) Retrovirology , vol.7
    • Herbein, G.1    Varin, A.2
  • 65
    • 85191983349 scopus 로고    scopus 로고
    • From monocytes to M1/M2 macrophages: Phenotypical versus functional differentiation
    • Italiani, P.; Boraschi, D. From monocytes to M1/M2 macrophages: Phenotypical versus functional differentiation. Front. Immunol. 2014, 5, e514.
    • (2014) Front. Immunol , vol.5
    • Italiani, P.1    Boraschi, D.2
  • 66
    • 39049155167 scopus 로고    scopus 로고
    • Is HIV infection a TNF receptor signalling-driven disease?
    • Herbein, G.; Khan, K.A. Is HIV infection a TNF receptor signalling-driven disease? Trends Immunol. 2008, 29, 61-67.
    • (2008) Trends Immunol , vol.29 , pp. 61-67
    • Herbein, G.1    Khan, K.A.2
  • 67
    • 0027340164 scopus 로고
    • A TH1-->TH2 switch is a critical step in the etiology of HIV infection. Immunol
    • Clerici, M.; Shearer, G.M. A TH1-->TH2 switch is a critical step in the etiology of HIV infection. Immunol. Today 1993, 14, 107-111.
    • (1993) Today , vol.14 , pp. 107-111
    • Clerici, M.1    Shearer, G.M.2
  • 68
    • 0347951393 scopus 로고    scopus 로고
    • The contribution of monocyte infection and trafficking to viral persistence, and maintenance of the viral reservoir in HIV infection
    • Crowe, S.; Zhu, T.; Muller, W.A. The contribution of monocyte infection and trafficking to viral persistence, and maintenance of the viral reservoir in HIV infection. J. Leukoc. Biol. 2003, 74, 635-641.
    • (2003) J. Leukoc. Biol , vol.74 , pp. 635-641
    • Crowe, S.1    Zhu, T.2    Muller, W.A.3
  • 69
    • 0036735168 scopus 로고    scopus 로고
    • HIV-1 in peripheral blood monocytes: An underrated viral source
    • Zhu, T. HIV-1 in peripheral blood monocytes: An underrated viral source. J. Antimicrob. Chemother. 2002, 50, 309-311.
    • (2002) J. Antimicrob. Chemother , vol.50 , pp. 309-311
    • Zhu, T.1
  • 70
    • 0036029868 scopus 로고    scopus 로고
    • The role of monocytes and macrophages in the pathogenesis of HIV-1 infection
    • Kedzierska, K.; Crowe, S.M. The role of monocytes and macrophages in the pathogenesis of HIV-1 infection. Curr. Med. Chem. 2002, 9, 1893-1903.
    • (2002) Curr. Med. Chem , vol.9 , pp. 1893-1903
    • Kedzierska, K.1    Crowe, S.M.2
  • 71
    • 84939945950 scopus 로고    scopus 로고
    • Role of myeloid cells in HIV-1-host interplay
    • Stevenson, M. Role of myeloid cells in HIV-1-host interplay. J. Neurovirol. 2014, doi:10.1007/s13365-014-0281-3.
    • (2014) J. Neurovirol
    • Stevenson, M.1
  • 72
    • 80053965899 scopus 로고    scopus 로고
    • Circulating monocytes are not a major reservoir of HIV-1 in elite suppressors
    • Spivak, A.M.; Salgado, M.; Rabi, S.A.; O’Connell, K.A.; Blankson, J.N. Circulating monocytes are not a major reservoir of HIV-1 in elite suppressors. J. Virol. 2011, 85, 10399-10403.
    • (2011) J. Virol , vol.85 , pp. 10399-10403
    • Spivak, A.M.1    Salgado, M.2    Rabi, S.A.3    O’Connell, K.A.4    Blankson, J.N.5
  • 73
    • 0026070668 scopus 로고
    • Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture
    • Schuitemaker, H.; Kootstra, N.A.; de Goede, R.E.; de Wolf, F.; Miedema, F.; Tersmette, M. Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture. J. Virol. 1991, 65, 356-363.
    • (1991) J. Virol , vol.65 , pp. 356-363
    • Schuitemaker, H.1    Kootstra, N.A.2    De Goede, R.E.3    De Wolf, F.4    Miedema, F.5    Tersmette, M.6
  • 75
    • 84944282429 scopus 로고
    • Virus isolation from and identification of HTLV-III/LAV-producing cells in brain tissue from a patient with AIDS
    • Gartner, S.; Markovits, P.; Markovitz, D.M.; Betts, R.F.; Popovic, M. Virus isolation from and identification of HTLV-III/LAV-producing cells in brain tissue from a patient with AIDS. JAMA 1986, 256, 2365-2371.
    • (1986) JAMA , vol.256 , pp. 2365-2371
    • Gartner, S.1    Markovits, P.2    Markovitz, D.M.3    Betts, R.F.4    Popovic, M.5
  • 76
    • 0023214674 scopus 로고
    • Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms
    • Koyanagi, Y.; Miles, S.; Mitsuyasu, R.T.; Merrill, J.E.; Vinters, H.V.; Chen, I.S. Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 1987, 236, 819-822.
    • (1987) Science , vol.236 , pp. 819-822
    • Koyanagi, Y.1    Miles, S.2    Mitsuyasu, R.T.3    Merrill, J.E.4    Vinters, H.V.5    Chen, I.S.6
  • 77
    • 33750439469 scopus 로고    scopus 로고
    • Continued evolution of HIV-1 circulating in blood monocytes with antiretroviral therapy: Genetic analysis of HIV-1 in monocytes and CD4+ T cells of patients with discontinued therapy
    • Llewellyn, N.; Zioni, R.; Zhu, H.; Andrus, T.; Xu, Y.; Corey, L.; Zhu, T. Continued evolution of HIV-1 circulating in blood monocytes with antiretroviral therapy: Genetic analysis of HIV-1 in monocytes and CD4+ T cells of patients with discontinued therapy. J. Leukoc. Biol. 2006, 80, 1118-1126.
    • (2006) J. Leukoc. Biol , vol.80 , pp. 1118-1126
    • Llewellyn, N.1    Zioni, R.2    Zhu, H.3    Andrus, T.4    Xu, Y.5    Corey, L.6    Zhu, T.7
  • 78
    • 3242732993 scopus 로고    scopus 로고
    • Zhu, T. Compartmentalization of human immunodeficiency virus type 1 between blood monocytes and CD4+ T cells during infection
    • Fulcher, J.A.; Hwangbo, Y.; Zioni, R.; Nickle, D.; Lin, X.; Heath, L.; Mullins, J.I.; Corey, L.; Zhu, T. Compartmentalization of human immunodeficiency virus type 1 between blood monocytes and CD4+ T cells during infection. J. Virol. 2004, 78, 7883-7893.
    • (2004) J. Virol , vol.78 , pp. 7883-7893
    • Fulcher, J.A.1    Hwangbo, Y.2    Zioni, R.3    Nickle, D.4    Lin, X.5    Heath, L.6    Mullins, J.I.7    Corey, L.8
  • 80
    • 77950585606 scopus 로고    scopus 로고
    • HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications
    • Valcour, V.G.; Shiramizu, B.T.; Shikuma, C.M. HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications. J. Leukoc. Biol. 2010, 87, 621-626.
    • (2010) J. Leukoc. Biol , vol.87 , pp. 621-626
    • Valcour, V.G.1    Shiramizu, B.T.2    Shikuma, C.M.3
  • 81
    • 27144448038 scopus 로고    scopus 로고
    • Human herpesvirus 8 enhances human immunodeficiency virus replication in acutely infected cells and induces reactivation in latently infected cells
    • Caselli, E.; Galvan, M.; Cassai, E.; Caruso, A.; Sighinolfi, L.; di Luca, D. Human herpesvirus 8 enhances human immunodeficiency virus replication in acutely infected cells and induces reactivation in latently infected cells. Blood 2005, 106, 2790-2797.
    • (2005) Blood , vol.106 , pp. 2790-2797
    • Caselli, E.1    Galvan, M.2    Cassai, E.3    Caruso, A.4    Sighinolfi, L.5    Di Luca, D.6
  • 82
    • 0030860537 scopus 로고    scopus 로고
    • Macrophages as a source of HIV during opportunistic infections
    • Orenstein, J.M.; Fox, C.; Wahl, S.M. Macrophages as a source of HIV during opportunistic infections. Science 1997, 276, 1857-1861.
    • (1997) Science , vol.276 , pp. 1857-1861
    • Orenstein, J.M.1    Fox, C.2    Wahl, S.M.3
  • 83
    • 34147187122 scopus 로고    scopus 로고
    • Efficient induction of HIV-1 replication in latently infected cells through contact with CD4+ T cells: Involvement of NF-kappaB activation
    • Qi, X.; Koya, Y.; Saitoh, T.; Saitoh, Y.; Shimizu, S.; Ohba, K.; Yamamoto, N.; Yamaoka, S.; Yamamoto, N. Efficient induction of HIV-1 replication in latently infected cells through contact with CD4+ T cells: Involvement of NF-kappaB activation. Virology 2007, 361, 325-334.
    • (2007) Virology , vol.361 , pp. 325-334
    • Qi, X.1    Koya, Y.2    Saitoh, T.3    Saitoh, Y.4    Shimizu, S.5    Ohba, K.6    Yamamoto, N.7    Yamaoka, S.8    Yamamoto, N.9
  • 85
    • 84926177380 scopus 로고    scopus 로고
    • Macrophages: Capturing HIV-infected T cells
    • Kugelberg, E. Macrophages: Capturing HIV-infected T cells. Nat. Rev. Immunol. 2015, 15, 2-3.
    • (2015) Nat. Rev. Immunol , vol.15 , pp. 2-3
    • Kugelberg, E.1
  • 86
    • 53849093455 scopus 로고    scopus 로고
    • Cell biology of HIV-1 infection of macrophages
    • Carter, C.A.; Ehrlich, L.S. Cell biology of HIV-1 infection of macrophages. Annu. Rev. Microbiol. 2008, 62, 425-443.
    • (2008) Annu. Rev. Microbiol , vol.62 , pp. 425-443
    • Carter, C.A.1    Ehrlich, L.S.2
  • 87
    • 29144494827 scopus 로고    scopus 로고
    • Regulation of neural cell survival by HIV-1 infection
    • Jones, G.; Power, C. Regulation of neural cell survival by HIV-1 infection. Neurobiol. Dis. 2006, 21, 1-17.
    • (2006) Neurobiol. Dis , vol.21 , pp. 1-17
    • Jones, G.1    Power, C.2
  • 88
    • 84904392112 scopus 로고    scopus 로고
    • Macrophages, immunity, and metabolic disease
    • McNelis, J.C.; Olefsky, J.M. Macrophages, immunity, and metabolic disease. Immunity 2014, 41, 36-48.
    • (2014) Immunity , vol.41 , pp. 36-48
    • McNelis, J.C.1    Olefsky, J.M.2
  • 89
    • 67649253072 scopus 로고    scopus 로고
    • HIV interactions with monocytes and dendritic cells: Viral latency and reservoirs
    • Coleman, C.M.; Wu, L. HIV interactions with monocytes and dendritic cells: Viral latency and reservoirs. Retrovirology 2009, 6, e51.
    • (2009) Retrovirology , vol.6
    • Coleman, C.M.1    Wu, L.2
  • 90
    • 84906215746 scopus 로고    scopus 로고
    • Mononuclear phagocyte accumulation in visceral tissue in HIV encephalitis: Evidence for increased monocyte/macrophage trafficking and altered differentiation
    • Fischer, T.; Wyatt, C.M.; D’Agati, V.D.; Croul, S.; McCourt, L.; Morgello, S.; Rappaport, J. Mononuclear phagocyte accumulation in visceral tissue in HIV encephalitis: Evidence for increased monocyte/macrophage trafficking and altered differentiation. Curr. HIV Res. 2014, 12, 201-212.
    • (2014) Curr. HIV Res , vol.12 , pp. 201-212
    • Fischer, T.1    Wyatt, C.M.2    D’Agati, V.D.3    Croul, S.4    McCourt, L.5    Morgello, S.6    Rappaport, J.7
  • 91
    • 84905673995 scopus 로고    scopus 로고
    • Brain inflammation is a common feature of HIV-infected patients without HIV encephalitis or productive brain infection
    • Tavazzi, E.; Morrison, D.; Sullivan, P.; Morgello, S.; Fischer, T. Brain inflammation is a common feature of HIV-infected patients without HIV encephalitis or productive brain infection. Curr. HIV Res. 2014, 12, 97-110.
    • (2014) Curr. HIV Res , vol.12 , pp. 97-110
    • Tavazzi, E.1    Morrison, D.2    Sullivan, P.3    Morgello, S.4    Fischer, T.5
  • 92
    • 33646860539 scopus 로고    scopus 로고
    • HIV-1 infection downregulates nuclear telomerase activity on lymphoblastoic cells without affecting the enzymatic components at the transcriptional level. AIDS Res. Hum
    • Reynoso, R.; Minces, L.; Salomon, H.; Quarleri, J. HIV-1 infection downregulates nuclear telomerase activity on lymphoblastoic cells without affecting the enzymatic components at the transcriptional level. AIDS Res. Hum. Retrovirus. 2006, 22, 425-429.
    • (2006) Retrovirus , vol.22 , pp. 425-429
    • Reynoso, R.1    Minces, L.2    Salomon, H.3    Quarleri, J.4
  • 93
    • 34147095386 scopus 로고    scopus 로고
    • Telomerase activity, hTERT expression, and phosphorylation are downregulated in CD4+ T lymphocytes infected with human immunodeficiency virus type 1 (HIV-1)
    • Franzese, O.; Adamo, R.; Pollicita, M.; Comandini, A.; Laudisi, A.; Perno, C.F.; Aquaro, S.; Bonmassar, E. Telomerase activity, hTERT expression, and phosphorylation are downregulated in CD4+ T lymphocytes infected with human immunodeficiency virus type 1 (HIV-1). J. Med. Virol. 2007, 79, 639-646.
    • (2007) J. Med. Virol , vol.79 , pp. 639-646
    • Franzese, O.1    Adamo, R.2    Pollicita, M.3    Comandini, A.4    Laudisi, A.5    Perno, C.F.6    Aquaro, S.7    Bonmassar, E.8
  • 95
    • 55749102699 scopus 로고    scopus 로고
    • Telomerase activity of HIV-1-specific CD8+ T cells: Constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors
    • Lichterfeld, M.; Mou, D.; Cung, T.D.; Williams, KL.; Waring, M.T.; Huang, J.; Pereyra, F.; Trocha, A.; Freeman, G.J.; Rosenberg, E.S., et al. Telomerase activity of HIV-1-specific CD8+ T cells: Constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors. Blood 2008, 112, 3679-3687.
    • (2008) Blood , vol.112 , pp. 3679-3687
    • Lichterfeld, M.1    Mou, D.2    Cung, T.D.3    Williams, K.L.4    Waring, M.T.5    Huang, J.6    Pereyra, F.7    Trocha, A.8    Freeman, G.J.9    Rosenberg, E.S.10
  • 96
    • 84890115573 scopus 로고    scopus 로고
    • Increased in vitro glial fibrillary acidic protein expression, telomerase activity, and telomere length after productive human immunodeficiency virus-1 infection in murine astrocytes
    • Ojeda, D.; Lopez-Costa, J.J.; Sede, M.; López, E.M.; Berria, M.I.; Quarleri, J. Increased in vitro glial fibrillary acidic protein expression, telomerase activity, and telomere length after productive human immunodeficiency virus-1 infection in murine astrocytes. J. Neurosci. Res. 2014, 92, 267-274.
    • (2014) J. Neurosci. Res , vol.92 , pp. 267-274
    • Ojeda, D.1    Lopez-Costa, J.J.2    Sede, M.3    López, E.M.4    Berria, M.I.5    Quarleri, J.6
  • 97
    • 84901265703 scopus 로고    scopus 로고
    • M-CSF inhibits anti-HIV-1 activity of IL-32, but they enhance M2-like phenotypes of macrophages
    • Osman, A.; Bhuyan, F.; Hashimoto, M.; Nasser, H.; Maekawa, T.; Suzu, S. M-CSF inhibits anti-HIV-1 activity of IL-32, but they enhance M2-like phenotypes of macrophages. J. Immunol. 2014, 192, 5083-5089.
    • (2014) J. Immunol , vol.192 , pp. 5083-5089
    • Osman, A.1    Bhuyan, F.2    Hashimoto, M.3    Nasser, H.4    Maekawa, T.5    Suzu, S.6
  • 98
    • 0038342442 scopus 로고    scopus 로고
    • HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection
    • Swingler, S.; Brichacek, B.; Jacque, J.M.; Ulich, C.; Zhou, J.; Stevenson, M. HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection. Nature 2003, 424, 213-219.
    • (2003) Nature , vol.424 , pp. 213-219
    • Swingler, S.1    Brichacek, B.2    Jacque, J.M.3    Ulich, C.4    Zhou, J.5    Stevenson, M.6
  • 99
    • 0035848864 scopus 로고    scopus 로고
    • HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell
    • Geleziunas, R.; Xu, W.; Takeda, K.; Ichijo, H.; Greene, W.C. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 2001, 410, 834-838.
    • (2001) Nature , vol.410 , pp. 834-838
    • Geleziunas, R.1    Xu, W.2    Takeda, K.3    Ichijo, H.4    Greene, W.C.5
  • 100
    • 0034541177 scopus 로고    scopus 로고
    • Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: Role for Nef and immune activation in viral persistence
    • Mahlknecht, U.; Deng, C.; Lu, M.C.; Greenough, T.C.; Sullivan, J.L.; O’Brien, W.A.; Herbein, G. Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: Role for Nef and immune activation in viral persistence. J. Immunol. 2000, 165, 6437-6446.
    • (2000) J. Immunol , vol.165 , pp. 6437-6446
    • Mahlknecht, U.1    Deng, C.2    Lu, M.C.3    Greenough, T.C.4    Sullivan, J.L.5    O’Brien, W.A.6    Herbein, G.7
  • 101
    • 0027497028 scopus 로고
    • Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals
    • Oyaizu, N.; McCloskey, T.W.; Coronesi, M.; Chirmule, N.; Kalyanaraman, V.S.; Pahwa, S. Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals. Blood 1993, 82, 3392-3400.
    • (1993) Blood , vol.82 , pp. 3392-3400
    • Oyaizu, N.1    McCcloskey, T.W.2    Coronesi, M.3    Chirmule, N.4    Kalyanaraman, V.S.5    Pahwa, S.6
  • 102
    • 0029655757 scopus 로고    scopus 로고
    • Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes
    • Badley, A.D.; McElhinny, J.A.; Leibson, P.J.; Lynch, D.H.; Alderson, M.R.; Paya, C.V. Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes. J. Virol. 1996, 70, 199-206.
    • (1996) J. Virol , vol.70 , pp. 199-206
    • Badley, A.D.1    McElhinny, J.A.2    Leibson, P.J.3    Lynch, D.H.4    Alderson, M.R.5    Paya, C.V.6
  • 103
    • 0031019006 scopus 로고    scopus 로고
    • Macrophage-dependent apoptosis of CD4+ T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor
    • Badley, A.D.; Dockrell, D.; Simpson, M.; Schut, R.; Lynch, D.H.; Leibson, P.; Paya, C.V. Macrophage-dependent apoptosis of CD4+ T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor. J. Exp. Med. 1997, 185, 55-64.
    • (1997) J. Exp. Med , vol.185 , pp. 55-64
    • Badley, A.D.1    Dockrell, D.2    Simpson, M.3    Schut, R.4    Lynch, D.H.5    Leibson, P.6    Paya, C.V.7
  • 105
  • 106
    • 0023696096 scopus 로고
    • Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome
    • Lahdevirta, J.; Maury, C.P.; Teppo, A.M.; Repo, H. Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome. Am. J. Med. 1988, 85, 289-291.
    • (1988) Am. J. Med , vol.85 , pp. 289-291
    • Lahdevirta, J.1    Maury, C.P.2    Teppo, A.M.3    Repo, H.4
  • 107
    • 0038618970 scopus 로고    scopus 로고
    • Monocytes treated with human immunodeficiency virus Tat kill uninfected CD4+ cells by a tumor necrosis factor-related apoptosis-induced ligand-mediated mechanism
    • Yang, Y.; Tikhonov, I.; Ruckwardt, T.J.; Djavani, M.; Zapata, J.C.; Pauza, C.D.; Salvato, M.S. Monocytes treated with human immunodeficiency virus Tat kill uninfected CD4+ cells by a tumor necrosis factor-related apoptosis-induced ligand-mediated mechanism. J. Virol. 2003, 77, 6700-6708.
    • (2003) J. Virol , vol.77 , pp. 6700-6708
    • Yang, Y.1    Tikhonov, I.2    Ruckwardt, T.J.3    Djavani, M.4    Zapata, J.C.5    Pauza, C.D.6    Salvato, M.S.7
  • 108
    • 0032505065 scopus 로고    scopus 로고
    • Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4
    • Herbein, G.; Mahlknecht, U.; Batliwalla, F.; Gregersen, P.; Pappas, T.; Butler, J.; O’Brien, W.A.; Verdin, E. Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4. Nature 1998, 395, 189-194.
    • (1998) Nature , vol.395 , pp. 189-194
    • Herbein, G.1    Mahlknecht, U.2    Batliwalla, F.3    Gregersen, P.4    Pappas, T.5    Butler, J.6    O’Brien, W.A.7    Verdin, E.8
  • 109
    • 0026706196 scopus 로고
    • Human immunodeficiency virus-infected monocyte-derived macrophages express surface gp120 and fuse with CD4 lymphoid cells in vitro: A possible mechanism of T lymphocyte depletion in vivo
    • Crowe, S.M.; Mills, J.; Elbeik, T.; Lifson, J.D.; Kosek, J.; Marshall, J.A.; Engleman, E.G.; McGrath, M.S. Human immunodeficiency virus-infected monocyte-derived macrophages express surface gp120 and fuse with CD4 lymphoid cells in vitro: A possible mechanism of T lymphocyte depletion in vivo. Clin. Immunol. Immunopathol. 1992, 5, 143-151.
    • (1992) Clin. Immunol. Immunopathol , vol.5 , pp. 143-151
    • Crowe, S.M.1    Mills, J.2    Elbeik, T.3    Lifson, J.D.4    Kosek, J.5    Marshall, J.A.6    Engleman, E.G.7    McGrath, M.S.8
  • 110
    • 0025090578 scopus 로고
    • Full-length recombinant CD4 and recombinant gp120 inhibit fusion between HIV infected macrophages and uninfected CD4-expressing T-lymphoblastoid cells
    • Crowe, S.M.; Mills, J.; Kirihara, J.; Boothman, J.; Marshall, J.A.; McGrath, M.S. Full-length recombinant CD4 and recombinant gp120 inhibit fusion between HIV infected macrophages and uninfected CD4-expressing T-lymphoblastoid cells. AIDS Res. Hum. Retrovirus. 1990, 6, 1031-1037.
    • (1990) AIDS Res. Hum. Retrovirus , vol.6 , pp. 1031-1037
    • Crowe, S.M.1    Mills, J.2    Kirihara, J.3    Boothman, J.4    Marshall, J.A.5    McGrath, M.S.6
  • 111
    • 84897997290 scopus 로고    scopus 로고
    • Efficient transfer of HIV-1 in trans and in cis from Langerhans dendritic cells and macrophages to autologous T lymphocytes
    • Peressin, M.; Proust, A.; Schmidt, S.; Su, B.; Lambotin, M.; Biedma, M.E.; Laumond, G.; Decoville, T.; Holl, V.; Moog, C. Efficient transfer of HIV-1 in trans and in cis from Langerhans dendritic cells and macrophages to autologous T lymphocytes. AIDS 2014, 28, 667-677.
    • (2014) AIDS , vol.28 , pp. 667-677
    • Peressin, M.1    Proust, A.2    Schmidt, S.3    Su, B.4    Lambotin, M.5    Biedma, M.E.6    Laumond, G.7    Decoville, T.8    Holl, V.9    Moog, C.10
  • 113
    • 0347951396 scopus 로고    scopus 로고
    • Monocyte/macrophage-derived CC chemokines and their modulation by HIV-1 and cytokines: A complex network of interactions influencing viral replication and AIDS pathogenesis
    • Fantuzzi, L.; Belardelli, F.; Gessani, S. Monocyte/macrophage-derived CC chemokines and their modulation by HIV-1 and cytokines: A complex network of interactions influencing viral replication and AIDS pathogenesis. J. Leukoc. Biol. 2003, 74, 719-725.
    • (2003) J. Leukoc. Biol , vol.74 , pp. 719-725
    • Fantuzzi, L.1    Belardelli, F.2    Gessani, S.3
  • 114
    • 0033559757 scopus 로고    scopus 로고
    • Human immunodeficiency virus replication induces monocyte chemotactic protein-1 in human macrophages and U937 promonocytic cells
    • Mengozzi, M.; de Filippi, C.; Transidico, P. Biswas, P.; Cota, M.; Ghezzi, S.; Vicenzi, E.; Mantovani, A.; Sozzani, S.; Poli, G. Human immunodeficiency virus replication induces monocyte chemotactic protein-1 in human macrophages and U937 promonocytic cells. Blood 1999, 93, 1851-1857.
    • (1999) Blood , vol.93 , pp. 1851-1857
    • Mengozzi, M.1    De Filippi, C.2    Transidico, P.3    Biswas, P.4    Cota, M.5    Ghezzi, S.6    Vicenzi, E.7    Mantovani, A.8    Sozzani, S.9    Poli, G.10
  • 117
    • 84906545516 scopus 로고    scopus 로고
    • HIV-1 Nef induces CCL5 production in astrocytes through p38-MAPK and PI3K/Akt pathway and utilizes NF-kB, CEBP and AP-1 transcription factors
    • Liu, X.; Shah, A.; Gangwani, M.R.; Silverstein, P.S.; Fu, M.; Kumar, A. HIV-1 Nef induces CCL5 production in astrocytes through p38-MAPK and PI3K/Akt pathway and utilizes NF-kB, CEBP and AP-1 transcription factors. Sci. Rep. 2014, 4, 4450.
    • (2014) Sci. Rep , vol.4 , pp. 4450
    • Liu, X.1    Shah, A.2    Gangwani, M.R.3    Silverstein, P.S.4    Fu, M.5    Kumar, A.6
  • 120
    • 0031848314 scopus 로고    scopus 로고
    • Relative potency of protease inhibitors in monocytes/macrophages acutely and chronically infected with human immunodeficiency virus
    • Perno, C.F.; Newcomb, F.M.; Davis, D.A.; Aquaro, S.; Humphrey, R.W.; Caliò, R.; Yarchoan, R. Relative potency of protease inhibitors in monocytes/macrophages acutely and chronically infected with human immunodeficiency virus. J. Infect. Dis. 1998, 178, 413-422.
    • (1998) J. Infect. Dis , vol.178 , pp. 413-422
    • Perno, C.F.1    Newcomb, F.M.2    Davis, D.A.3    Aquaro, S.4    Humphrey, R.W.5    Caliò, R.6    Yarchoan, R.7
  • 124
    • 0032518290 scopus 로고    scopus 로고
    • The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
    • Kim, R.B.; Fromm, M.F.; Wandel, C.; Leake, B.; Wood, A.J.; Roden, D.M.; Wilkinson, G.R. The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J. Clin. Invest. 1998, 101, 289-294.
    • (1998) J. Clin. Invest , vol.101 , pp. 289-294
    • Kim, R.B.1    Fromm, M.F.2    Wandel, C.3    Leake, B.4    Wood, A.J.5    Roden, D.M.6    Wilkinson, G.R.7
  • 126
    • 84896690200 scopus 로고    scopus 로고
    • Role of P-glycoprotein in the distribution of the HIV protease inhibitor atazanavir in the brain and male genital tract
    • Robillard, K.R.; Chan, G.N.; Zhang, G.; la Porte, C.; Cameron, W.; Bendayan, R. Role of P-glycoprotein in the distribution of the HIV protease inhibitor atazanavir in the brain and male genital tract. Antimicrob. Agents Chemother. 2014, 58, 1713-1722.
    • (2014) Antimicrob. Agents Chemother , vol.58 , pp. 1713-1722
    • Robillard, K.R.1    Chan, G.N.2    Zhang, G.3    La Porte, C.4    Cameron, W.5    Bendayan, R.6
  • 127
    • 0031788927 scopus 로고    scopus 로고
    • Fridland, A. Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters
    • Srinivas, R.V.; Middlemas, D.; Flynn, P.; Fridland, A. Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters. Antimicrob. Agents Chemother. 1998, 42, 3157-3162.
    • (1998) Antimicrob. Agents Chemother , vol.42 , pp. 3157-3162
    • Srinivas, R.V.1    Middlemas, D.2    Flynn, P.3
  • 129
    • 0034121122 scopus 로고    scopus 로고
    • Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes
    • Choo, E.F.; Leake, B.; Wandel, C.; Imamura, H.; Wood, A.J.; Wilkinson, G.R.; Kim, R.B. Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes. Drug Metab. Dispos. 2000, 28, 655-660.
    • (2000) Drug Metab. Dispos , vol.28 , pp. 655-660
    • Choo, E.F.1    Leake, B.2    Wandel, C.3    Imamura, H.4    Wood, A.J.5    Wilkinson, G.R.6    Kim, R.B.7
  • 130
    • 84872811617 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein by HIV protease inhibitors increases intracellular accumulation of berberine in murine and human macrophages
    • Zha, W.; Wang, G.; Xu, W.; Liu, X.; Wang, Y.; Zha, B.S.; Shi, J.; Zhao, Q.; Gerk, P.M.; Studer, E., et al. Inhibition of P-glycoprotein by HIV protease inhibitors increases intracellular accumulation of berberine in murine and human macrophages. PLOS ONE 2013, 8, e54349.
    • (2013) PLOS ONE , vol.8
    • Zha, W.1    Wang, G.2    Xu, W.3    Liu, X.4    Wang, Y.5    Zha, B.S.6    Shi, J.7    Zhao, Q.8    Gerk, P.M.9    Studer, E.10
  • 131
    • 0035895214 scopus 로고    scopus 로고
    • Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans
    • Igarashi, T.; Brown, C.R.; Endo, Y.; Buckler-White, A.; Plishka, R.; Bischofberger, N.; Hirsch, V.; Martin, M.A. Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans. Proc. Natl. Acad. Sci. USA 2001, 98, 658-663.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 658-663
    • Igarashi, T.1    Brown, C.R.2    Endo, Y.3    Buckler-White, A.4    Plishka, R.5    Bischofberger, N.6    Hirsch, V.7    Martin, M.A.8
  • 132
    • 79960319717 scopus 로고    scopus 로고
    • Single mutations in HIV integrase confer high-level resistance to raltegravir in primary human macrophages
    • Marsden, M.D.; Avancena, P.; Kitchen, C.M.; Hubbard, T.; Zack, J.A. Single mutations in HIV integrase confer high-level resistance to raltegravir in primary human macrophages. Antimicrob. Agents Chemother. 2011, 55, 3696-3702.
    • (2011) Antimicrob. Agents Chemother , vol.55 , pp. 3696-3702
    • Marsden, M.D.1    Avancena, P.2    Kitchen, C.M.3    Hubbard, T.4    Zack, J.A.5
  • 134
    • 73549107210 scopus 로고    scopus 로고
    • Novel approaches to inhibiting HIV-1 replication
    • Adamson, C.S.; Freed, E.O. Novel approaches to inhibiting HIV-1 replication. Antiviral Res. 2010, 85, 119-141.
    • (2010) Antiviral Res , vol.85 , pp. 119-141
    • Adamson, C.S.1    Freed, E.O.2
  • 136
    • 84862777555 scopus 로고    scopus 로고
    • SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
    • Lahouassa, H.; Daddacha, W.; Hofmann, H.; Ayinde, D.; Logue, E.C.; Dragin, L.; Bloch, N.; Maudet, C.; Bertrand, M.; Gramberg, T., et al. SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates. Nat. Immunol. 2012, 13, 223-228.
    • (2012) Nat. Immunol , vol.13 , pp. 223-228
    • Lahouassa, H.1    Daddacha, W.2    Hofmann, H.3    Ayinde, D.4    Logue, E.C.5    Dragin, L.6    Bloch, N.7    Maudet, C.8    Bertrand, M.9    Gramberg, T.10
  • 137
    • 84920901203 scopus 로고    scopus 로고
    • Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance
    • Kyei, G.B.; Cheng, X.; Ramani, R.; Ratner, L. Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance. Cell Host Microbe 2015, 17, 98-106.
    • (2015) Cell Host Microbe , vol.17 , pp. 98-106
    • Kyei, G.B.1    Cheng, X.2    Ramani, R.3    Ratner, L.4
  • 139
    • 0037043699 scopus 로고    scopus 로고
    • Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
    • Sheehy, A.M.; Gaddis, N.C.; Choi, J.D.; Malim, M.H. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 2002, 418, 646-650.
    • (2002) Nature , vol.418 , pp. 646-650
    • Sheehy, A.M.1    Gaddis, N.C.2    Choi, J.D.3    Malim, M.H.4
  • 140
    • 31944438580 scopus 로고    scopus 로고
    • Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1 activity
    • Peng, G.; Lei, K.J.; Jin, W.; Greenwell-Wild, T.; Wahl, S.M. Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1 activity. J. Exp. Med. 2006, 203, 41-46.
    • (2006) J. Exp. Med , vol.203 , pp. 41-46
    • Peng, G.1    Lei, K.J.2    Jin, W.3    Greenwell-Wild, T.4    Wahl, S.M.5
  • 143
    • 84872672203 scopus 로고    scopus 로고
    • Novel factors interfering with human immunodeficiency virus-type 1 replication in vivo and in vitro
    • Vicenzi, E.; Poli, G. Novel factors interfering with human immunodeficiency virus-type 1 replication in vivo and in vitro. Tissue Antigens 2013, 81, 61-71.
    • (2013) Tissue Antigens , vol.81 , pp. 61-71
    • Vicenzi, E.1    Poli, G.2
  • 144
    • 38549095979 scopus 로고    scopus 로고
    • Tetherin inhibits retrovirus release and isantagonized by HIV-1 Vpu
    • Neil, S.J.; Zang, T.; Bieniasz, P.D. Tetherin inhibits retrovirus release and isantagonized by HIV-1 Vpu. Nature 2008, 451, 425-430.
    • (2008) Nature , vol.451 , pp. 425-430
    • Neil, S.J.1    Zang, T.2    Bieniasz, P.D.3
  • 145
  • 146
    • 1542288934 scopus 로고    scopus 로고
    • The cytoplasmic body component TRIM5a restricts HIV-1infection in old world monkeys
    • Stremlau, M.; Owens, C.M.; Perron, M.J.; Kiessling, M.; Autissier, P.; Sodroski, J. The cytoplasmic body component TRIM5a restricts HIV-1infection in old world monkeys. Nature 2004, 427, 848-853.
    • (2004) Nature , vol.427 , pp. 848-853
    • Stremlau, M.1    Owens, C.M.2    Perron, M.J.3    Kiessling, M.4    Autissier, P.5    Sodroski, J.6
  • 149
    • 33745363486 scopus 로고    scopus 로고
    • HIV integration site selection: Targeting in macrophages and the effects of different routes of viral entry
    • Barr, S.D.; Ciuffi, A.; Leipzig, J.; Shinn, P.; Ecker, J.R.; Bushman, F.D. HIV integration site selection: Targeting in macrophages and the effects of different routes of viral entry. Mol. Ther. 2006, 14, 218-225.
    • (2006) Mol. Ther , vol.14 , pp. 218-225
    • Barr, S.D.1    Ciuffi, A.2    Leipzig, J.3    Shinn, P.4    Ecker, J.R.5    Bushman, F.D.6
  • 150
    • 21744440917 scopus 로고    scopus 로고
    • Preferential HIV-1 integration sites in macrophages and HIV-associated malignancies
    • Killebrew, D.A.; Troelstrup, D.; Shiramizu, B. Preferential HIV-1 integration sites in macrophages and HIV-associated malignancies. Cell. Mol. Biol. 2004, 50, OL581-OL589.
    • (2004) Cell. Mol. Biol , vol.50
    • Killebrew, D.A.1    Troelstrup, D.2    Shiramizu, B.3
  • 151
    • 45749157597 scopus 로고    scopus 로고
    • Characterization of the early steps of infection of primary blood monocytes by human immunodeficiency virus type 1
    • Arfi, V.; Riviere, L.; Jarrosson-Wuilleme, L.; Goujon, C.; Rigal, D.; Darlix, J.L.; Cimarelli, A. Characterization of the early steps of infection of primary blood monocytes by human immunodeficiency virus type 1. J. Virol. 2008, 82, 6557-6565.
    • (2008) J. Virol , vol.82 , pp. 6557-6565
    • Arfi, V.1    Riviere, L.2    Jarrosson-Wuilleme, L.3    Goujon, C.4    Rigal, D.5    Darlix, J.L.6    Cimarelli, A.7
  • 156
    • 84866885992 scopus 로고    scopus 로고
    • Macrophages and their relevance in human immunodeficiency virus type 1 infection
    • Koppensteiner, H.; Brack-Werner, R.; Schindler, M. Macrophages and their relevance in human immunodeficiency virus type 1 infection. Retrovirology 2012, 9, e82.
    • (2012) Retrovirology , vol.9
    • Koppensteiner, H.1    Brack-Werner, R.2    Schindler, M.3
  • 157
    • 0028643585 scopus 로고
    • Interleukin 10 inhibits initial reverse transcription of human immunodeficiency virus type 1 and mediates a virostatic latent state in primary blood-derived human macrophages in vitro
    • Montaner, L.J.; Griffin, P.; Gordon, S. Interleukin 10 inhibits initial reverse transcription of human immunodeficiency virus type 1 and mediates a virostatic latent state in primary blood-derived human macrophages in vitro. J. Gen. Virol. 1994, 75, 3393-3400.
    • (1994) J. Gen. Virol , vol.75 , pp. 3393-3400
    • Montaner, L.J.1    Griffin, P.2    Gordon, S.3


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