Mononuclear phagocyte accumulation in visceral tissue in HIV encephalitis: Evidence for increased monocyte/macrophage trafficking and altered differentiation

Current HIV Research

Volumn 12, Issue 3, 2014, Pages 201-212

  Fischer, Tracy ^a   Wyatt, Christina M ^b   D'Agati, Vivette D ^c   Croul, Sidney ^a,d   McCourt, Laura ^a   Morgello, Susan ^b   Rappaport, Jay ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c New York Presbyterian Columbia University Medical Center   (United States)

^d UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Cd16; Cns; Co morbidity; Hiv; Hivan; Macrophage; Pyelonephritis

Indexed keywords

CD14 ANTIGEN; CD16 ANTIGEN; CD68 ANTIGEN; GAG PROTEIN; KI 67 ANTIGEN; LEUKOCYTE ANTIGEN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; COMORBIDITY; CONTROLLED STUDY; FOCAL GLOMERULOSCLEROSIS; HIV ASSOCIATED DEMENTIA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY; LYMPH NODE; MACROPHAGE; MONOCYTE; MONONUCLEAR PHAGOCYTE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN; VIRUS ENCEPHALITIS; VISCERA; ADULT; FEMALE; IMMUNOLOGY; LIVER; MALE; MICROSCOPY; MIDDLE AGED; PATHOLOGY;

ADULT; AIDS DEMENTIA COMPLEX; ANTIGENS, CD; FEMALE; HIV CORE PROTEIN P24; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; KIDNEY; LIVER; LYMPH NODES; MACROPHAGES; MALE; MICROSCOPY; MIDDLE AGED; MONOCYTES; SPLEEN;

EID: 84906215746     PISSN: 1570162X     EISSN: 18734251     Source Type: Journal    
DOI: 10.2174/1570162X12666140713165141     Document Type: Article

References (36)

1. Glass JD, Fedor H, Wesselingh SL, McArthur JC. Immunocytochemical uantitation of human immunodeficiency virus in the brain: correlations with dementia. Ann Neurol 38(5): 755-62. (1995).
2. Pulliam L, Gascon R, Stubblebine M, McGuire D, McGrath MS. Unique monocyte subset in patients with AIDS dementia. Lancet 349(9053): 692-5. (1997).
3. Fischer-Smith T, Tedaldi EM, Rappaport J. CD163/CD16 coexpression by circulating monocytes/macrophages in HIV: potential biomarkers for HIV infection and AIDS progression. AIDS Res Hum Retroviruses 24(3): 417-21. (2008).
4. Fischer-Smith T, Croul S, Sverstiuk AE, et al. CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection. J Neurovirol 7(6): 528-41. (2001).
5. Fischer-Smith T, Croul S, Adeniyi A, et al. Macrophage/microglial accumulation and proliferating cell nuclear antigen expression in the central nervous system in human immunodeficiency virus encephalopathy. The American journal of pathology 164(6): 2089-99. (2004).
6. Scherberich JE, Nockher WA. Blood monocyte phenotypes and soluble endotoxin receptor CD14 in systemic inflammatory diseases and patients with chronic renal failure. Nephrol Dial Transplant 15(5): 574-8. (2000).
7. Morgello S, GelmanBB, Kozlowski PB, et al. The National NeuroAIDS Tissue Consortium: a new paradigm in brain banking with an emphasis on infectious disease. Neuropathol Appl Neurobiol 27(4): 326-35. (2001).
8. Al-Shatti T, Barr AE, Safadi FF, Amin M, Barbe MF. Increase in inflammatory cytokines in median nerves in a rat model of repetitive motion injury. J Neuroimmunol 167(1-2): 13-22. (2005).
9. Lin EY, Nguyen AV, Russell RG, Pollard JW. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 193(6): 727-40. (2001).
10. Campbell IK, Rich MJ, Bischof RJ, Hamilton JA. The colonystimulating factors and collagen-induced arthritis: exacerbation of disease by M-CSF and G-CSF and requirement for endogenous MCSF. J Leukoc Biol 68(1): 144-50. (2000).
11. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW, Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112(12): 1796-808. (2003).
12. Patsouris D, Li PP, Thapar D, Chapman J, Olefsky JM, Neels JG. Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metab 8(4): 301-9. (2008).
13. Suzumura A. Neuron-microglia interaction in neuroinflammation. Curr Protein Pept Sci 14(1): 16-20. (2013).
14. Fischer-Smith T, Bell C, Croul S, Lewis M, Rappaport J. Monocyte/macrophage trafficking in acquired immunodeficiency syndrome encephalitis: lessons from human and nonhuman primate studies. J Neurovirol 14(4): 318-26. (2008).
15. Sandler NG, Wand H, Roque A, et al. Plasma levels of soluble CD14 independently predict mortality in HIV infection. J Infect Dis 203(6): 780-90. (2011).
16. Lyons JL, Uno H, Ancuta P, et al. Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection. J Acquir Immune Defic Syndr 57(5): 371-9. (2011).
17. Hailman E, Vasselon T, Kelley M, et al. Stimulation of macrophages and neutrophils by complexes of lipopolysaccharide and soluble CD14. J Immunol 156(11): 4384-90. (1996).
18. Tsoukas CM, Bernard NF, Abrahamowicz M, et al. Effect of splenectomy on slowing human immunodeficiency virus disease progression. Arch Surg 133(1): 25-31. (1998).
19. Bernard NF, Chernoff DN, Tsoukas CM. Effect of splenectomy on T-cell subsets and plasma HIV viral titers in HIV-infected patients. J Hum Virol 1(5): 338-45. (1998).
20. Yang Y, Gubler MC, Beaufils H. Dysregulation of podocyte phenotype in idiopathic collapsing glomerulopathy and HIVassociated nephropathy. Nephron 91(3): 416-23. (2002).
21. Schwartz MM, Korbet SM, Rydell J, Borok R, Genchi R. Primary focal segmental glomerular sclerosis in adults: prognostic value of histologic variants. Am J Kidney Dis 25(6): 845-52. (1995).
22. Barisoni L, Mokrzycki M, Sablay L, Nagata M, Yamase H, Mundel P. Podocyte cell cycle regulation and proliferation in collapsing glomerulopathies. Kidney Int 58(1): 137-43. (2000).
23. Shankland SJ, Eitner F, Hudkins KL, Goodpaster T, D'Agati V, Alpers CE. Differential expression of cyclin-dependent kinase inhibitors in human glomerular disease: role in podocyte proliferation and maturation. Kidney Int 58(2): 674-83. (2000).
24. Tanji N, Ross MD, Tanji K, et al. Detection and localization of HIV-1 DNA in renal tissues by in situ polymerase chain reaction. Histology and histopathology 21(4): 393-401. (2006).
25. Winston JA, Bruggeman LA, Ross MD, et al. Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection. N Engl J Med 344(26): 1979-84.(2001).
26. Adih WK, Selik RM, Xiaohong H. Trends in Diseases Reported on US Death Certificates That Mentioned HIV Infection, 1996-2006. J Int Assoc Physicians AIDS Care (Chic) 10(1): 5-11. (2011).
27. D'Agati V, Appel GB. Renal pathology of human immunodeficiency virus infection. Semin Nephrol 18(4): 406-21. (1998).
28. Cohen AH, Nast CC. HIV-associated nephropathy. A unique combined glomerular, tubular, and interstitial lesion. Mod Pathol 1(2): 87-97. (1988).
29. Wyatt CM, Morgello S, Katz-Malamed R, et al. The spectrum of kidney disease in patients with AIDS in the era of antiretroviral therapy. Kidney Int 75(4): 428-34. (2009).
30. D'Agati V, Suh JI, Carbone L, Cheng JT, Appel G. Pathology of HIV-associated nephropathy: a detailed morphologic and comparative study. Kidney Int 35(6): 1358-70. (1989).
31. Duffield JS. Macrophages and immunologic inflammation of the kidney. Semin Nephrol 30(3): 234-54. (2010).
32. Milazzo L, Menzaghi B, Corvasce S, et al. Safety of statin therapy in HIV/hepatitis C virus-coinfected patients. J Acquir Immune Defic Syndr 46(2): 258-60. (2007).
33. McCutchan JA, Wu JW, Robertson K, et al. HIV suppression by HAART preserves cognitive function in advanced, immunereconstituted AIDS patients. Aids 21(9): 1109-17. (2007).
34. Szczech LA. Monitoring HIV patients' kidney function in clinical practice. What is known about kidney disease in other clinical contexts can help guide HIV care providers in monitoring kidney function in their patients. J Watch AIDS Clin Care 21(11): 92-4. (2009).
35. Agins B, Bacon O, Balano K, et al. Guide for HIV/AIDS Clinical Care. (Ed: HHS). Washington, D.C.; p. 611 (2011).
36. Walker JA, Sulciner ML, Nowicki KD, Miller AD, Burdo TH, Williams KC. Elevated Numbers of CD163 Macrophages in Hearts of Simian Immunodeficiency Virus-Infected Monkeys Correlate with Cardiac Pathology and Fibrosis. AIDS Res Hum Retroviruses 2014).