메뉴 건너뛰기




Volumn 410, Issue 6830, 2001, Pages 834-838

HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; ENZYME INHIBITION; TISSUE; VIRUSES;

EID: 0035848864     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35071111     Document Type: Article
Times cited : (297)

References (30)
  • 2
    • 0029034517 scopus 로고
    • Analysis of apoptosis in lymph nodes or HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden
    • (1995) J. Immunol. , vol.154 , pp. 5555-5566
    • Muro-Cacho, C.A.1    Pantaleo, G.2    Fauci, A.S.3
  • 3
    • 0028912254 scopus 로고
    • Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes
    • (1995) Nature Med. , vol.1 , pp. 129-134
    • Finkel, T.H.1
  • 4
    • 0030744349 scopus 로고    scopus 로고
    • Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells
    • (1997) J. Exp. Med. , vol.186 , pp. 7-16
    • Xu, X.N.1
  • 5
    • 0033519235 scopus 로고    scopus 로고
    • Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain
    • (1999) J. Exp. Med. , vol.189 , pp. 1489-1496
    • Xu, X.N.1
  • 7
    • 0028265466 scopus 로고
    • High expression of APO-1 (CD95) on T lymphocytes from human immunodeficiency virus-1-infected children
    • (1994) Blood , vol.83 , pp. 3101-3103
    • Debatin, K.M.1
  • 9
    • 0031049287 scopus 로고    scopus 로고
    • - lymphocyte depletion and human immunodeficiency virus replication
    • (1997) Blood , vol.89 , pp. 1357-1363
    • Sloand, E.M.1
  • 11
    • 14444281569 scopus 로고    scopus 로고
    • Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
    • (1997) Science , vol.275 , pp. 90-94
    • Ichijo, H.1
  • 12
    • 0032158987 scopus 로고    scopus 로고
    • ASK1 is essential for JNK/SAPK activation by TRAF2
    • (1998) Mol. Cell , vol.2 , pp. 389-395
    • Nishitoh, H.1
  • 13
    • 0031019006 scopus 로고    scopus 로고
    • + T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor
    • (1997) J. Exp. Med. , vol.185 , pp. 55-64
    • Badley, A.D.1
  • 14
    • 0032505065 scopus 로고    scopus 로고
    • + T cells is mediated by macrophages through interaction of HIV gpI20 with chemokine receptor CXCR4
    • (1998) Nature , vol.395 , pp. 189-194
    • Herbein, G.1
  • 16
    • 0029655757 scopus 로고    scopus 로고
    • Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes
    • (1996) J. Virol. , vol.70 , pp. 199-206
    • Badley, A.D.1
  • 17
    • 0032080283 scopus 로고    scopus 로고
    • Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
    • (1998) EMBO J. , vol.17 , pp. 2596-2606
    • Saitoh, M.1
  • 21
    • 0033013962 scopus 로고    scopus 로고
    • Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking
    • (1999) J. Virol. , vol.73 , pp. 1964-1973
    • Mangasarian, A.1    Piguet, V.2    Wang, J.K.3    Chen, Y.L.4    Trono, D.5
  • 23
    • 0032488027 scopus 로고    scopus 로고
    • A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor
    • (1998) Curr. Biol. , vol.8 , pp. 1235-1238
    • Bresnahan, P.A.1
  • 26
    • 0025743306 scopus 로고
    • Importance of the nef gene for maintenance of high virus loads and for development of AIDS
    • (1991) Cell , vol.65 , pp. 651-662
    • Kestler, H.W.1
  • 27
    • 0033104495 scopus 로고    scopus 로고
    • Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
    • (1999) EMBO J. , vol.18 , pp. 1223-1234
    • Asada, M.1
  • 30
    • 0033578923 scopus 로고    scopus 로고
    • Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector
    • (1999) Science , vol.285 , pp. 1920-1923
    • Orth, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.