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doi: 10.1093/infdis/jit308. This interesting paper pointed out that the pool of cellular HIV-1 reservoirs in the gut may be different from that observed in peripheral blood, and highlighted the existence of non-CD4(+) T leukocytes as a new potential target of HIV infection. These results are important in order to set up effective therapeutic strategies aimed at achieving HIV cure
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NIAID HIV Vaccine Trials Network: Comprehensive assessment of HIV target cells in the distal human gut suggests increasing HIV susceptibility toward the anus
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on behalf of This study highlights a different distribution of macrophages between the colum and the rectum suggesting that these 2 gut tracts could act as distinct anatomical compartments
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This interesting study highlights the IL-7 capability in promoting HIV-1 replication in cervico-vaginal tissue. This has strong implication in sexual transmission of HIV-1 infection
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