The Myeloid U937 Skin Sensitization Test (U-SENS) addresses the activation of dendritic cell event in the adverse outcome pathway for skin sensitization

Toxicology in Vitro

Volumn 29, Issue 5, 2015, Pages 901-916

  Piroird, Cécile ^a   Ovigne, Jean Marc ^a   Rousset, Françoise ^a   Martinozzi Teissier, Silvia ^a   Gomes, Charles ^a   Cotovio, José ^a   Alépée, Nathalie ^a  

^a L ORÉAL RECHERCHE   (France)

Author keywords

CD86 induction; Dendritic cells; MUSST; Predictivity; Skin sensitization; U SENS

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 2 AMINOPHENOL; 2 METHYL 4 ISOTHIAZOLIN 3 ONE; BENZOYL PEROXIDE; CD86 ANTIGEN; CHLORPROMAZINE; CITRAL; CITRIC ACID; DICHROMATE POTASSIUM; DIPHENCYPRONE; DODECYL GALLATE; DYE; ETHYLENEDIAMINE; FARNESOL; FRAGRANCE; FUMARIC ACID DIMETHYL ESTER; GALLIC ACID PROPYL ESTER; GLUTARALDEHYDE; GLYCEROL; GOLD CHLORIDE; ISOEUGENOL; MALEIC ACID DIETHYL ESTER; PHENYL BENZOATE; PHENYLENEDIAMINE; PRESERVATIVE; SALICYLIC ACID; SULFANILIC ACID; TETRACHLORSALAN; THIOGLYCEROL; UNCLASSIFIED DRUG; ALLERGEN;

ACCURACY; ADVERSE OUTCOME; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; BIOASSAY; CELL ACTIVATION; CELL MATURATION; CELL MOTILITY; CHEMICAL BINDING; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; CYTOTOXICITY; DENDRITIC CELL; DISEASE CLASSIFICATION; DRUG POTENCY; FALSE POSITIVE RESULT; FLOW CYTOMETRY; HAPTENATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTERMETHOD COMPARISON; LOCAL LYMPH NODE ASSAY; LYMPH NODE; LYMPHOCYTE PROLIFERATION; MICHAEL ADDITION; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PREDICTION; PREVALENCE; RECEIVER OPERATING CHARACTERISTIC; RELIABILITY; REPRODUCIBILITY; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; SKIN SENSITIZATION; SKIN SENSITIZATION TEST; T LYMPHOCYTE; U937 CELL LINE; ANIMAL; ANIMAL TESTING ALTERNATIVE; CONTACT DERMATITIS; IMMUNOLOGY; MOUSE; PROCEDURES; SKIN TEST; TOXICITY TESTING;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; ANIMALS; DENDRITIC CELLS; DERMATITIS, CONTACT; HUMANS; LOCAL LYMPH NODE ASSAY; MICE; REPRODUCIBILITY OF RESULTS; SKIN TESTS; TOXICITY TESTS; U937 CELLS;

EID: 84927918649     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2015.03.009     Document Type: Article

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