Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals

Toxicology in Vitro

Volumn 25, Issue 6, 2011, Pages 1162-1168

  Bauch, Caroline ^a,b   Kolle, Susanne N ^a   Fabian, Eric ^a   Pachel, Christina ^a,c   Ramirez, Tzutzuy ^a   Wiench, Benjamin ^a,d   Wruck, Christoph J ^b   Ravenzwaay, Bennard van ^a   Landsiedel, Robert ^a  

^a BASF SE   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Alternative methods; EU cosmetic directive; In vitro; Prediction model; Skin sensitization

Indexed keywords

CD86 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1;

ACCURACY; ANALYTIC METHOD; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL STRAIN; CONTROLLED STUDY; DENDRITIC CELL ACTIVATION ASSAY; DIRECT PEPTIDE REACTIVITY ASSAY; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERMETHOD COMPARISON; LOCAL LYMPH NODE ASSAY; PEPTIDE ANALYSIS; PERFORMANCE MEASUREMENT SYSTEM; REPORTER GENE; SENSITIVITY AND SPECIFICITY; SKIN SENSITIZATION; STANDARD; VALIDATION STUDY;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; ANTIOXIDANTS; CELL LINE; DENDRITIC CELLS; DERMATITIS, ALLERGIC CONTACT; HUMANS; PEPTIDES; REPRODUCIBILITY OF RESULTS; RESPONSE ELEMENTS; SENSITIVITY AND SPECIFICITY; SKIN IRRITANCY TESTS;

ANIMALIA;

EID: 79960928365     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.05.030     Document Type: Article

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