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Volumn 128, Issue C, 2014, Pages 103-137

Epigenetics of depression

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DESIPRAMINE; DEXAMETHASONE; DOPAMINE; ESCITALOPRAM; FK 506 BINDING PROTEIN; FLUOXETINE; NEUROTROPHIN; NORADRENALIN; SEROTONIN; SEROTONIN TRANSPORTER;

EID: 84927738137     PISSN: 18771173     EISSN: 18780814     Source Type: Book Series    
DOI: 10.1016/B978-0-12-800977-2.00005-X     Document Type: Chapter
Times cited : (23)

References (144)
  • 1
    • 84873634267 scopus 로고    scopus 로고
    • American Psychiatric Association., Arlington, VA: American Psychiatric Publishing
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Arlington, VA: American Psychiatric Publishing; 2013.
    • (2013) Diagnostic and Statistical Manual of Mental Disorders. 5th Ed
  • 2
    • 84902486234 scopus 로고    scopus 로고
    • Major depressive disorder in DSM-5: Implications for clinical practice and research of changes from DSM-IV
    • Uher R, Payne JL, Pavlova B, Perlis RH. Major depressive disorder in DSM-5: implications for clinical practice and research of changes from DSM-IV. Depress Anxiety. 2013;31:459-471.
    • (2013) Depress Anxiety. , vol.31 , pp. 459-471
    • Uher, R.1    Payne, J.L.2    Pavlova, B.3    Perlis, R.H.4
  • 3
    • 84887954461 scopus 로고    scopus 로고
    • Genomics and the classification of mental illness: Focus on broader categories
    • Uher R. Genomics and the classification of mental illness: focus on broader categories. Genome Med. 2013;5:97.
    • (2013) Genome Med. , vol.5 , pp. 97
    • Uher, R.1
  • 4
    • 84887259083 scopus 로고    scopus 로고
    • Global burden of disease attributable to mental and substance use disorders: Findings from the Global Burden of Disease Study 2010
    • Whiteford HA, Degenhardt L, Rehm J, et al. Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet. 2013;382:1575-1586.
    • (2013) Lancet. , vol.382 , pp. 1575-1586
    • Whiteford, H.A.1    Degenhardt, L.2    Rehm, J.3
  • 6
    • 84875465140 scopus 로고    scopus 로고
    • The epidemiology of depression across cultures
    • Kessler RC, Bromet EJ. The epidemiology of depression across cultures. Annu Rev Public Health. 2013;34:119-138.
    • (2013) Annu Rev Public Health. , vol.34 , pp. 119-138
    • Kessler, R.C.1    Bromet, E.J.2
  • 7
    • 20344385026 scopus 로고    scopus 로고
    • Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R)
    • Kessler RC, Berglund PA, Demler O, Jin R, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Arch Gen Psychiatry. 2005;62:593-602.
    • (2005) Arch Gen Psychiatry. , vol.62 , pp. 593-602
    • Kessler, R.C.1    Berglund, P.A.2    Demler, O.3    Jin, R.4    Walters, E.E.5
  • 8
    • 79960659664 scopus 로고    scopus 로고
    • Cross-national epidemiology of DSM-IV major depressive episode
    • Bromet E, Andrade LH, Hwang I, et al. Cross-national epidemiology of DSM-IV major depressive episode. BMC Med. 2011;9:90.
    • (2011) BMC Med. , vol.9 , pp. 90
    • Bromet, E.1    Andrade, L.H.2    Hwang, I.3
  • 9
    • 33847119026 scopus 로고    scopus 로고
    • Cell adhesion molecules: Signaling functions at the synapse
    • Dalva MB, McClelland AC, Kayser MS. Cell adhesion molecules: signaling functions at the synapse. Nat Rev Neurosci. 2007;8:206-220.
    • (2007) Nat Rev Neurosci. , vol.8 , pp. 206-220
    • Dalva, M.B.1    McClelland, A.C.2    Kayser, M.S.3
  • 11
    • 68049144803 scopus 로고    scopus 로고
    • A randomized, doubleblind, placebo-controlled study of testosterone treatment in hypogonadal older men with subthreshold depression (dysthymia or minor depression)
    • Shores MM, Kivlahan DR, Sadak TI, Li EJ, Matsumoto AM. A randomized, doubleblind, placebo-controlled study of testosterone treatment in hypogonadal older men with subthreshold depression (dysthymia or minor depression). J Clin Psychiatry. 2009;70:1009-1016.
    • (2009) J Clin Psychiatry. , vol.70 , pp. 1009-1016
    • Shores, M.M.1    Kivlahan, D.R.2    Sadak, T.I.3    Li, E.J.4    Matsumoto, A.M.5
  • 12
    • 33645530757 scopus 로고    scopus 로고
    • Risk for new onset of depression during the menopausal transition: The Harvard study of moods and cycles
    • Cohen LS, Soares CN, Vitonis AF, Otto MW, Harlow BL. Risk for new onset of depression during the menopausal transition: the Harvard study of moods and cycles. Arch Gen Psychiatry. 2006;63:385-390.
    • (2006) Arch Gen Psychiatry. , vol.63 , pp. 385-390
    • Cohen, L.S.1    Soares, C.N.2    Vitonis, A.F.3    Otto, M.W.4    Harlow, B.L.5
  • 13
    • 63549121682 scopus 로고    scopus 로고
    • Examining the intersection of sex and stress in modeling neuropsychiatric disorders
    • Goel N, Bale TL. Examining the intersection of sex and stress in modeling neuropsychiatric disorders. J Neuroendocrinol. 2009;21:415-420.
    • (2009) J Neuroendocrinol. , vol.21 , pp. 415-420
    • Goel, N.1    Bale, T.L.2
  • 17
    • 0031690726 scopus 로고    scopus 로고
    • Monoamine dysfunction and the pathophysiology and treatment of depression
    • Charney DS. Monoamine dysfunction and the pathophysiology and treatment of depression. J Clin Psychiatry. 1998;14:11-14.
    • (1998) J Clin Psychiatry. , vol.14 , pp. 11-14
    • Charney, D.S.1
  • 18
    • 78349241786 scopus 로고    scopus 로고
    • Linking molecules to mood: New insight into the biology of depression
    • Krishnan V, Nestler EJ. Linking molecules to mood: new insight into the biology of depression. Am J Psychiatry. 2010;167:1305-1320.
    • (2010) Am J Psychiatry. , vol.167 , pp. 1305-1320
    • Krishnan, V.1    Nestler, E.J.2
  • 19
    • 30044433660 scopus 로고    scopus 로고
    • Evaluation of outcomes with citalopram for depression using measurement-based care in STAR∗D: Implications for clinical practice
    • Trivedi MH, Rush AJ, Wisniekski SR, et al. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR∗D: implications for clinical practice. Am J Psychiatry. 2006;163:28-40.
    • (2006) Am J Psychiatry. , vol.163 , pp. 28-40
    • Trivedi, M.H.1    Rush, A.J.2    Wisniekski, S.R.3
  • 20
    • 84885214350 scopus 로고    scopus 로고
    • Antidepressant efficacy of ketamine in treatment-resistant major depression: A two-site randomized controlled trial
    • Murrough JW, Iosifescu DV, Chang LC, et al. Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial. Am J Psychiatry. 2013;170:1134-1142.
    • (2013) Am J Psychiatry. , vol.170 , pp. 1134-1142
    • Murrough, J.W.1    Iosifescu, D.V.2    Chang, L.C.3
  • 21
    • 0037462449 scopus 로고    scopus 로고
    • The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
    • Egan MF, Kojima M, Callicott JH, et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell. 2003;112:257-269.
    • (2003) Cell. , vol.112 , pp. 257-269
    • Egan, M.F.1    Kojima, M.2    Callicott, J.H.3
  • 22
    • 84868208976 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients
    • Laje G, Lally N, Mathews D, et al. Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients. Biol Psychiatry. 2012;72:e27-e28.
    • (2012) Biol Psychiatry. , vol.72 , pp. e27-e28
    • Laje, G.1    Lally, N.2    Mathews, D.3
  • 23
    • 37049030994 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity
    • Lipsky RH, Marini AM. Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity. Ann N Y Acad Sci. 2007;1122:130-143.
    • (2007) Ann N y Acad Sci. , vol.1122 , pp. 130-143
    • Lipsky, R.H.1    Marini, A.M.2
  • 24
    • 16844372468 scopus 로고    scopus 로고
    • Effects of tryptophan depletion on serum levels of brain-derived neurotrophic factor in unmedicated patients with remitted depression and healthy subjects
    • Neumeister A, Yuan P, Yound TA, et al. Effects of tryptophan depletion on serum levels of brain-derived neurotrophic factor in unmedicated patients with remitted depression and healthy subjects. Am J Psychiatry. 2005;162:805-807.
    • (2005) Am J Psychiatry. , vol.162 , pp. 805-807
    • Neumeister, A.1    Yuan, P.2    Yound, T.A.3
  • 25
    • 33646840434 scopus 로고    scopus 로고
    • Effects of genes and stress on the neurobiology of depression
    • Mann JJ, Currier D. Effects of genes and stress on the neurobiology of depression. Int Rev Neurobiol. 2006;73:153-189.
    • (2006) Int Rev Neurobiol. , vol.73 , pp. 153-189
    • Mann, J.J.1    Currier, D.2
  • 26
    • 84888410322 scopus 로고    scopus 로고
    • Neuroplasticity and the next wave of antidepressant strategies
    • Hayley S, Litteljohn D. Neuroplasticity and the next wave of antidepressant strategies. Front Cell Neurosci. 2013;7:218.
    • (2013) Front Cell Neurosci. , vol.7 , pp. 218
    • Hayley, S.1    Litteljohn, D.2
  • 27
    • 0038771149 scopus 로고    scopus 로고
    • Alterations of serum levels of brainderived neurotrophic factor (BDNF) in depressed patients with or without antidepressants
    • Shimizu E, Hashimoto K, Okamura N, et al. Alterations of serum levels of brainderived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry. 2003;54:70-75.
    • (2003) Biol Psychiatry. , vol.54 , pp. 70-75
    • Shimizu, E.1    Hashimoto, K.2    Okamura, N.3
  • 28
    • 84869096094 scopus 로고    scopus 로고
    • Epigenetics of the depressed brain: Role of histone acetylation and methylation
    • Sun H, Kennedy PJ, Nestler EJ. Epigenetics of the depressed brain: role of histone acetylation and methylation. Neuropsychopharmacology. 2013;38:124-137.
    • (2013) Neuropsychopharmacology. , vol.38 , pp. 124-137
    • Sun, H.1    Kennedy, P.J.2    Nestler, E.J.3
  • 29
    • 84862169503 scopus 로고    scopus 로고
    • Type i interferons impair BDNF-induced cell signaling and neurotrophic activity in differentiated human SH-SY5Y neuroblastoma cells and mouse primary cortical neurons
    • Dedoni S, Olianas MC, Ingianni A, Onali P. Type I interferons impair BDNF-induced cell signaling and neurotrophic activity in differentiated human SH-SY5Y neuroblastoma cells and mouse primary cortical neurons. J Neurochem. 2012;122:58-71.
    • (2012) J Neurochem. , vol.122 , pp. 58-71
    • Dedoni, S.1    Olianas, M.C.2    Ingianni, A.3    Onali, P.4
  • 30
    • 32444451651 scopus 로고    scopus 로고
    • Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
    • Berton O, McClung CA, Dileone RJ, et al. Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science. 2006;31:864-868.
    • (2006) Science. , vol.31 , pp. 864-868
    • Berton, O.1    McClung, C.A.2    Dileone, R.J.3
  • 31
    • 84921348554 scopus 로고    scopus 로고
    • Effects of escitalopram on serum BDNF levels in elderly patients with depression: A preliminary report
    • Martocchia A, Curto M, Scaccianoce S, et al. Effects of escitalopram on serum BDNF levels in elderly patients with depression: a preliminary report. Aging Clin Exp Res. 2014;26(4):461-464.
    • (2014) Aging Clin Exp Res. , vol.26 , Issue.4 , pp. 461-464
    • Martocchia, A.1    Curto, M.2    Scaccianoce, S.3
  • 32
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: A convergence of mechanisms
    • Pittenger C, Duman RS. Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology. 2008;33:88-109.
    • (2008) Neuropsychopharmacology. , vol.33 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 33
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan V, Nestler EJ. The molecular neurobiology of depression. Nature. 2008;455:894-902.
    • (2008) Nature. , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 34
    • 84877287517 scopus 로고    scopus 로고
    • The neural plasticity theory of depression: Assessing the roles of adult neurogenesis and PSA-NCAM within the hippocampus
    • Wainwright SR, Galea LA. The neural plasticity theory of depression: assessing the roles of adult neurogenesis and PSA-NCAM within the hippocampus. Neural Plast. 2013;2013:805497.
    • (2013) Neural Plast. , vol.2013 , pp. 805497
    • Wainwright, S.R.1    Galea, L.A.2
  • 35
    • 0033797445 scopus 로고    scopus 로고
    • The corticosteroid receptor hypothesis of depression
    • Holsboer F.The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 2000;23:477-501.
    • (2000) Neuropsychopharmacology , vol.23 , pp. 477-501
    • Holsboer, F.1
  • 36
  • 37
    • 69549131133 scopus 로고    scopus 로고
    • Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory
    • Yuen EY, Liu W, Karatsoreos IN, Feng J, McEwen BS, Yann Z. Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory. Proc Natl Acad Sci USA. 2009;106:14075-14079.
    • (2009) Proc Natl Acad Sci USA. , vol.106 , pp. 14075-14079
    • Yuen, E.Y.1    Liu, W.2    Karatsoreos, I.N.3    Feng, J.4    McEwen, B.S.5    Yann, Z.6
  • 38
    • 0029830422 scopus 로고    scopus 로고
    • The dexamethasone suppression test in patients with mood disorders
    • Crowley GT, Khatami M, Vasavada N. The dexamethasone suppression test in patients with mood disorders. J Clin Psychiatry. 1996;57:470-484.
    • (1996) J Clin Psychiatry. , vol.57 , pp. 470-484
    • Crowley, G.T.1    Khatami, M.2    Vasavada, N.3
  • 39
  • 40
    • 0018831862 scopus 로고
    • Response to dexamethasone and subtype of depression
    • Brown WA, Shuey I. Response to dexamethasone and subtype of depression. Arch Gen Psychiatry. 1980;37:747-751.
    • (1980) Arch Gen Psychiatry. , vol.37 , pp. 747-751
    • Brown, W.A.1    Shuey, I.2
  • 41
    • 0029830422 scopus 로고    scopus 로고
    • The dexamethasone suppression test in patients with mood disorders
    • Rush AJ, Giles DE, Schlesser MA, et al. The dexamethasone suppression test in patients with mood disorders. J Clin Psychiatry. 1996;57:470-484.
    • (1996) J Clin Psychiatry. , vol.57 , pp. 470-484
    • Rush, A.J.1    Giles, D.E.2    Schlesser, M.A.3
  • 42
    • 84875276637 scopus 로고    scopus 로고
    • Associations between cognitive performance and cortisol reaction to the DEX/CRH test in patients recovered from depression
    • Behnken A, Bellingrath S, Symanczik JP, et al. Associations between cognitive performance and cortisol reaction to the DEX/CRH test in patients recovered from depression. Psychoneuroendocrinology. 2013;38:447-454.
    • (2013) Psychoneuroendocrinology. , vol.38 , pp. 447-454
    • Behnken, A.1    Bellingrath, S.2    Symanczik, J.P.3
  • 43
    • 0030614486 scopus 로고    scopus 로고
    • Decreased hypothalamic-pituitary-adrenal axis sensitivity to cortisol feedback inhibition in human aging
    • Wilkinson CW, Peskind ER, Raskind MA. Decreased hypothalamic-pituitary-adrenal axis sensitivity to cortisol feedback inhibition in human aging. Neuroendocrinology. 1997;65:79-90.
    • (1997) Neuroendocrinology. , vol.65 , pp. 79-90
    • Wilkinson, C.W.1    Peskind, E.R.2    Raskind, M.A.3
  • 44
    • 0029821816 scopus 로고    scopus 로고
    • Dexamethasone suppression test: Corticosteroid receptors regulation in mononuclear leukocytes in young and aged subjects
    • [accessed December, 2013]
    • Zovato S, Simoncini M, Gottardo C, et al. Dexamethasone suppression test: corticosteroid receptors regulation in mononuclear leukocytes in young and aged subjects. Aging. 1996;8:360-364. http://www.who.int/mediacentre/factsheets/fs369/en/[accessed December, 2013].
    • (1996) Aging. , vol.8 , pp. 360-364
    • Zovato, S.1    Simoncini, M.2    Gottardo, C.3
  • 45
    • 33847654714 scopus 로고    scopus 로고
    • Hippocampal volume reduction and HPAsystem activity in major depression
    • Colla M, Kronenberg G, Deuschle M, et al. Hippocampal volume reduction and HPAsystem activity in major depression. J Psychiatr Res. 2007;41:553-560.
    • (2007) J Psychiatr Res. , vol.41 , pp. 553-560
    • Colla, M.1    Kronenberg, G.2    Deuschle, M.3
  • 46
    • 54149102607 scopus 로고    scopus 로고
    • Posterior hippocampal volumes are associated with remission rates in patients with major depressive disorder
    • MacQueen GM, Yucel K, Taylor VH, Macdonald K, Joffe R. Posterior hippocampal volumes are associated with remission rates in patients with major depressive disorder. Biol Psychiatry. 2008;64:880-883.
    • (2008) Biol Psychiatry. , vol.64 , pp. 880-883
    • Macqueen, G.M.1    Yucel, K.2    Taylor, V.H.3    Macdonald, K.4    Joffe, R.5
  • 47
    • 50249084453 scopus 로고    scopus 로고
    • Brain structural and functional abnormalities in mood disorders: Implications for neurocircuitry models of depression
    • Drevets WC, Price JL, Furey ML. Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. Brain Struct Funct. 2008;213:93-118.
    • (2008) Brain Struct Funct. , vol.213 , pp. 93-118
    • Drevets, W.C.1    Price, J.L.2    Furey, M.L.3
  • 48
    • 0033800486 scopus 로고    scopus 로고
    • Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders
    • Sapolsky RM. Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch Gen Psychiatry. 2000;57:925-935.
    • (2000) Arch Gen Psychiatry. , vol.57 , pp. 925-935
    • Sapolsky, R.M.1
  • 49
    • 84873523115 scopus 로고    scopus 로고
    • How does the brain deal with cumulative stress? A review with focus on developmental stress, HPA axis function and hippocampal structure in humans
    • Frodl T, O'Keane V. How does the brain deal with cumulative stress? A review with focus on developmental stress, HPA axis function and hippocampal structure in humans. Neurobiol Dis. 2013;52:24-37.
    • (2013) Neurobiol Dis. , vol.52 , pp. 24-37
    • Frodl, T.1    O'Keane, V.2
  • 50
    • 0030450928 scopus 로고    scopus 로고
    • A prospective study of psychiatric and psychological aspects of Cushing's syndrome
    • Kelly WF, Kelly MJ, Faragher B. A prospective study of psychiatric and psychological aspects of Cushing's syndrome. Clin Endocrinol (Oxf ). 1996;45:715-720.
    • (1996) Clin Endocrinol (Oxf ). , vol.45 , pp. 715-720
    • Kelly, W.F.1    Kelly, M.J.2    Faragher, B.3
  • 51
    • 84866178460 scopus 로고    scopus 로고
    • Long-term cognitive impairments and attention deficits in patients with Cushing's disease and cortisol-producing adrenal adenoma in remission
    • Ragnarsson O, Berglund P, Eder DN, Hohannsson G. Long-term cognitive impairments and attention deficits in patients with Cushing's disease and cortisol-producing adrenal adenoma in remission. J Clin Endocrinol Metab. 2012;97:E1640-E1648.
    • (2012) J Clin Endocrinol Metab. , vol.97 , pp. E1640-E1648
    • Ragnarsson, O.1    Berglund, P.2    Eder, D.N.3    Hohannsson, G.4
  • 52
    • 34250206674 scopus 로고    scopus 로고
    • Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression-A potential biomarker?
    • Ising M, Horstmann S, Kloiber S, et al. Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression-a potential biomarker? Biol Psychiatry. 2007;62:47-54.
    • (2007) Biol Psychiatry. , vol.62 , pp. 47-54
    • Ising, M.1    Horstmann, S.2    Kloiber, S.3
  • 53
    • 80052050190 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis buffers stress responses and depressive behaviour
    • Snyder JS, Soumier A, Brewer M, Pickel J, Cameron HA. Adult hippocampal neurogenesis buffers stress responses and depressive behaviour. Nature. 2011;476:458-461.
    • (2011) Nature. , vol.476 , pp. 458-461
    • Snyder, J.S.1    Soumier, A.2    Brewer, M.3    Pickel, J.4    Cameron, H.A.5
  • 54
    • 0036126742 scopus 로고    scopus 로고
    • The chronic psychosocial stress paradigm in male tree shrews: Evaluation of a novel animal model for depressive disorders
    • Van Kampen M, Kramer M, Hiemke C, Flügge G, Fuchs E. The chronic psychosocial stress paradigm in male tree shrews: evaluation of a novel animal model for depressive disorders. Stress. 2002;5:37-46.
    • (2002) Stress. , vol.5 , pp. 37-46
    • Van Kampen, M.1    Kramer, M.2    Hiemke, C.3    Flügge, G.4    Fuchs, E.5
  • 55
    • 0035985675 scopus 로고    scopus 로고
    • Social stress in tree shrews: Effects on physiology, brain function, and behavior of subordinate individuals
    • Fuchs E, Flügge G. Social stress in tree shrews: effects on physiology, brain function, and behavior of subordinate individuals. Pharmacol Biochem Behav. 2002;7:247-258.
    • (2002) Pharmacol Biochem Behav. , vol.7 , pp. 247-258
    • Fuchs, E.1    Flügge, G.2
  • 56
    • 15944393798 scopus 로고    scopus 로고
    • American Psychiatric Association, Arlington, Virginia: American Psychiatric Association [accessed December, 2013]
    • American Psychiatric Association. APA Practice Guideline for the Treatment of Patients with Major Depressive Disorder. 3rd ed. Arlington, Virginia: American Psychiatric Association; 2013. http://www.psychiatryonline.com/pracGuide/pracGuideTopic-7.aspx [accessed December, 2013].
    • (2013) APA Practice Guideline for the Treatment of Patients with Major Depressive Disorder. 3rd Ed
  • 57
    • 33751338530 scopus 로고    scopus 로고
    • Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR∗D report
    • Rush AJ, Trivedi MH, Wisniewski SR, et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR∗D report. Am J Psychiatry. 2006;163:1905-1917.
    • (2006) Am J Psychiatry. , vol.163 , pp. 1905-1917
    • Rush, A.J.1    Trivedi, M.H.2    Wisniewski, S.R.3
  • 58
    • 84865854959 scopus 로고    scopus 로고
    • Onset, time course and trajectories of improvement with antidepressants
    • Lam RW. Onset, time course and trajectories of improvement with antidepressants. Eur Neuropsychopharmacol. 2012;22(Suppl. 3):S492-S498.
    • (2012) Eur Neuropsychopharmacol. , vol.22 , pp. S492-S498
    • Lam, R.W.1
  • 59
    • 84867709301 scopus 로고    scopus 로고
    • Epigenetics, depression and antidepressant treatment
    • Menke A, Klengel T, Binder EB. Epigenetics, depression and antidepressant treatment. Curr Pharm Des. 2012;18:5879-5889.
    • (2012) Curr Pharm Des. , vol.18 , pp. 5879-5889
    • Menke, A.1    Klengel, T.2    Binder, E.B.3
  • 61
    • 67849098089 scopus 로고    scopus 로고
    • Vulnerability to depression: What is the role of stress genes in gene x environment interaction?
    • El Hage W, Powell JF, Surguladze SA. Vulnerability to depression: what is the role of stress genes in gene x environment interaction? Psychol Med. 2009;39: 1407-1411.
    • (2009) Psychol Med. , vol.39 , pp. 1407-1411
    • El Hage, W.1    Powell, J.F.2    Surguladze, S.A.3
  • 62
    • 0042528720 scopus 로고    scopus 로고
    • Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
    • Santarelli L, Saxe M, Gross C, et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science. 2003;301:805-809.
    • (2003) Science. , vol.301 , pp. 805-809
    • Santarelli, L.1    Saxe, M.2    Gross, C.3
  • 63
    • 67349216843 scopus 로고    scopus 로고
    • The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling
    • Bessa JM, Ferreira D, Melo I, et al. The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling. Mol Psychiatry. 2009;14:764-773.
    • (2009) Mol Psychiatry. , vol.14 , pp. 764-773
    • Bessa, J.M.1    Ferreira, D.2    Melo, I.3
  • 64
    • 84865208083 scopus 로고    scopus 로고
    • Is neurogenesis relevant in depression and in the mechanism of antidepressant drug action? A critical review
    • Tang SW, Helmeste D, Leonard B. Is neurogenesis relevant in depression and in the mechanism of antidepressant drug action? A critical review. World J Biol Psychiatry. 2012;13:402-412.
    • (2012) World J Biol Psychiatry. , vol.13 , pp. 402-412
    • Tang, S.W.1    Helmeste, D.2    Leonard, B.3
  • 65
    • 34247856025 scopus 로고    scopus 로고
    • Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates
    • Perera TD, Coplan JD, Lisanby SH, et al. Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates. J Neurosci. 2007;27:4894-4901.
    • (2007) J Neurosci. , vol.27 , pp. 4894-4901
    • Perera, T.D.1    Coplan, J.D.2    Lisanby, S.H.3
  • 67
    • 77049099103 scopus 로고    scopus 로고
    • The genetics of major depression: Moving beyond the monoamine hypothesis
    • Shyn SI, Hamilton SP. The genetics of major depression: moving beyond the monoamine hypothesis. Psychiatr Clin North Am. 2010;33:125-140.
    • (2010) Psychiatr Clin North Am. , vol.33 , pp. 125-140
    • Shyn, S.I.1    Hamilton, S.P.2
  • 68
    • 79151475816 scopus 로고    scopus 로고
    • Novel loci for major depression identified by genomewide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies
    • Shyn SI, Shi J, Kraft JB, et al. Novel loci for major depression identified by genomewide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies. Mol Psychiatry. 2011;16:202-215.
    • (2011) Mol Psychiatry. , vol.16 , pp. 202-215
    • Shyn, S.I.1    Shi, J.2    Kraft, J.B.3
  • 70
    • 33646072813 scopus 로고    scopus 로고
    • Gain-of-function genotypes are linked to obsessivecompulsive disorder
    • Hu X, Lipsky RH, Zhu G, et al. Gain-of-function genotypes are linked to obsessivecompulsive disorder. Am J Hum Genet. 2006;78:815-826.
    • (2006) Am J Hum Genet. , vol.78 , pp. 815-826
    • Hu, X.1    Lipsky, R.H.2    Zhu, G.3
  • 71
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • Lesch KP, Bengel D, Heils A, et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science. 1996;2(74): 1527-1531.
    • (1996) Science. , vol.2 , Issue.74 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3
  • 72
    • 33745726353 scopus 로고    scopus 로고
    • The genetics of depression: A review
    • Levinson DF. The genetics of depression: a review. Biol Psychiatry. 2006;60:84-92.
    • (2006) Biol Psychiatry. , vol.60 , pp. 84-92
    • Levinson, D.F.1
  • 73
    • 34347374871 scopus 로고    scopus 로고
    • Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression
    • Hu X-Z, Rush AJ, Charney D, et al. Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. Arch Gen Psychiatry. 2007;64:783-792.
    • (2007) Arch Gen Psychiatry. , vol.64 , pp. 783-792
    • Hu, X.-Z.1    Rush, A.J.2    Charney, D.3
  • 74
    • 33646062299 scopus 로고    scopus 로고
    • Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment
    • McMahon FJ, Buervenich S, Charney D, et al. Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment. Am J Hum Genet. 2006;78:804-814.
    • (2006) Am J Hum Genet. , vol.78 , pp. 804-814
    • McMahon, F.J.1    Buervenich, S.2    Charney, D.3
  • 76
    • 79952033418 scopus 로고    scopus 로고
    • The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: Evidence of genetic moderation
    • Karg K, Burmeister M, Shedden K, Sen S. The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. Arch Gen Psychiatry. 2011;68:444-454.
    • (2011) Arch Gen Psychiatry. , vol.68 , pp. 444-454
    • Karg, K.1    Burmeister, M.2    Shedden, K.3    Sen, S.4
  • 77
    • 84927773335 scopus 로고    scopus 로고
    • Differential responsiveness of the serotonin transporter gene in pharmacologic treatment of adult depression: Potential for understanding epigenetic-genetic interactions
    • July 17-22
    • Hu X, Tian F, Ecklund JM, Lipsky RH. Differential responsiveness of the serotonin transporter gene in pharmacologic treatment of adult depression: potential for understanding epigenetic-genetic interactions. In: Gordon Research Conference, Human Genetics and Genomics July 17-22; 2011.
    • (2011) Gordon Research Conference, Human Genetics and Genomics
    • Hu, X.1    Tian, F.2    Ecklund, J.M.3    Lipsky, R.H.4
  • 78
    • 42249087793 scopus 로고    scopus 로고
    • Estimation of significance thresholds for genomewide association scans
    • Dudbridge F, Gusnanto A. Estimation of significance thresholds for genomewide association scans. Genet Epidemiol. 2008;32:227-234.
    • (2008) Genet Epidemiol. , vol.32 , pp. 227-234
    • Dudbridge, F.1    Gusnanto, A.2
  • 79
    • 84879892380 scopus 로고    scopus 로고
    • A mega-analysis of genome-wide association studies for major depressive disorder
    • Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium
    • Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Ripke S, Wray NR, et al. A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry. 2013;18:497-511.
    • (2013) Mol Psychiatry. , vol.18 , pp. 497-511
    • Ripke, S.1    Wray, N.R.2
  • 81
    • 84857371055 scopus 로고    scopus 로고
    • Genetic variation in the calcium/calmodulin-dependent protein kinase (CaMK) pathway is associated with antidepressant response in females
    • Shi Y, Yuan Y, Xu Z, et al. Genetic variation in the calcium/calmodulin-dependent protein kinase (CaMK) pathway is associated with antidepressant response in females. J Affect Disord. 2012;136:558-566.
    • (2012) J Affect Disord. , vol.136 , pp. 558-566
    • Shi, Y.1    Yuan, Y.2    Xu, Z.3
  • 82
    • 84870837641 scopus 로고    scopus 로고
    • ABCB1 polymorphism predicts escitalopram dose needed for remission in major depression
    • Singh AB, Bousman CA, Ng CH, Byron K, Berk M. ABCB1 polymorphism predicts escitalopram dose needed for remission in major depression. Transl Psychiatry. 2012;2: e198.
    • (2012) Transl Psychiatry. , vol.2 , pp. e198
    • Singh, A.B.1    Bousman, C.A.2    Ng, C.H.3    Byron, K.4    Berk, M.5
  • 83
    • 79961126893 scopus 로고    scopus 로고
    • Genome-wide association studies of antidepressant outcome: A brief review
    • Laje G, McMahon FJ. Genome-wide association studies of antidepressant outcome: a brief review. Prog Neuropsychopharmacol Biol Psychiatry. 2011;35:1553-1557.
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry. , vol.35 , pp. 1553-1557
    • Laje, G.1    McMahon, F.J.2
  • 84
    • 71649105262 scopus 로고    scopus 로고
    • A genomewide association study of citalopram response in major depressive disorder
    • Garriock HA, Kraft JB, Shyn SI, et al. A genomewide association study of citalopram response in major depressive disorder. Biol Psychiatry. 2010;167:133-138.
    • (2010) Biol Psychiatry. , vol.167 , pp. 133-138
    • Garriock, H.A.1    Kraft, J.B.2    Shyn, S.I.3
  • 85
    • 69949184308 scopus 로고    scopus 로고
    • A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    • Ising M, Lucae S, Binder EB, et al. A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Arch Gen Psychiatry. 2009;66:966-975.
    • (2009) Arch Gen Psychiatry. , vol.66 , pp. 966-975
    • Ising, M.1    Lucae, S.2    Binder, E.B.3
  • 86
    • 77951779878 scopus 로고    scopus 로고
    • Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    • Uher R, Perroud N, Ng MY, et al. Genome-wide pharmacogenetics of antidepressant response in the GENDEP project. Am J Psychiatry. 2010;167:555-564.
    • (2010) Am J Psychiatry. , vol.167 , pp. 555-564
    • Uher, R.1    Perroud, N.2    Ng, M.Y.3
  • 87
    • 33847257284 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients
    • Serretti A, Kato M, De Ronchi D, Kinoshita T. Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients. Mol Psychiatry. 2007;12(3):247-257.
    • (2007) Mol Psychiatry. , vol.12 , Issue.3 , pp. 247-257
    • Serretti, A.1    Kato, M.2    De Ronchi, D.3    Kinoshita, T.4
  • 88
    • 77956170298 scopus 로고    scopus 로고
    • Antidepressant response and the serotonin transporter gene-linked polymorphic region
    • Taylor MJ, Sen S, Bhagwagar Z. Antidepressant response and the serotonin transporter gene-linked polymorphic region. Biol Psychiatry. 2010;68:536-543.
    • (2010) Biol Psychiatry. , vol.68 , pp. 536-543
    • Taylor, M.J.1    Sen, S.2    Bhagwagar, Z.3
  • 89
    • 84857236103 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy
    • Porcelli S, Fabbri C, Serretti A. Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy. Eur Neuropsychopharmacol. 2012;22(4):239-258.
    • (2012) Eur Neuropsychopharmacol. , vol.22 , Issue.4 , pp. 239-258
    • Porcelli, S.1    Fabbri, C.2    Serretti, A.3
  • 90
    • 9644252785 scopus 로고    scopus 로고
    • Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment
    • Binder EB, Salyakina D, Lichtner P, et al. Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nat Genet. 2004;36:1319-1325.
    • (2004) Nat Genet. , vol.36 , pp. 1319-1325
    • Binder, E.B.1    Salyakina, D.2    Lichtner, P.3
  • 91
    • 70350731477 scopus 로고    scopus 로고
    • The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders
    • Binder EB. The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology. 2009;34(Suppl. 1):S186-S195.
    • (2009) Psychoneuroendocrinology. , vol.34 , pp. S186-S195
    • Binder, E.B.1
  • 92
    • 44349188699 scopus 로고    scopus 로고
    • The FKBP5-gene in depression and treatment response-an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR∗D) Cohort
    • Lekman M, Laje G, Charney D, et al. The FKBP5-gene in depression and treatment response-an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR∗D) Cohort. Biol Psychiatry. 2008;63:1103-1110.
    • (2008) Biol Psychiatry. , vol.63 , pp. 1103-1110
    • Lekman, M.1    Laje, G.2    Charney, D.3
  • 93
    • 84871717397 scopus 로고    scopus 로고
    • Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions
    • Klengel T, Mehta D, Anacker C, et al. Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci. 2013;16:33-41.
    • (2013) Nat Neurosci. , vol.16 , pp. 33-41
    • Klengel, T.1    Mehta, D.2    Anacker, C.3
  • 94
    • 0033810465 scopus 로고    scopus 로고
    • Genetic epidemiology of major depression: Review and meta-analysis
    • Sullivan PF, Neale MC, Kendler KS. Genetic epidemiology of major depression: review and meta-analysis. Am J Psychiatry. 2000;157:1552-1562.
    • (2000) Am J Psychiatry. , vol.157 , pp. 1552-1562
    • Sullivan, P.F.1    Neale, M.C.2    Kendler, K.S.3
  • 95
    • 35748949251 scopus 로고    scopus 로고
    • What predicts psychological resilience after disaster? the role of demographics, resources, and life stress
    • Bonanno GA, Galea S, Bucciarelli A, Vlahov D. What predicts psychological resilience after disaster? The role of demographics, resources, and life stress. J Consult Clin Psychol. 2007;7:671-682.
    • (2007) J Consult Clin Psychol. , vol.7 , pp. 671-682
    • Bonanno, G.A.1    Galea, S.2    Bucciarelli, A.3    Vlahov, D.4
  • 96
    • 84886725397 scopus 로고    scopus 로고
    • Depression, anxiety and loss of resilience after multiple traumas: An illustration of a mediated moderation model of sensitization in a group of children who survived the Nazi Holocaust
    • Fossion P, Leys C, Kempenaers C, Braun S, Verbanck P, Linkowski P. Depression, anxiety and loss of resilience after multiple traumas: an illustration of a mediated moderation model of sensitization in a group of children who survived the Nazi Holocaust. J Affect Disord. 2013;151:973-979.
    • (2013) J Affect Disord. , vol.151 , pp. 973-979
    • Fossion, P.1    Leys, C.2    Kempenaers, C.3    Braun, S.4    Verbanck, P.5    Linkowski, P.6
  • 97
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
    • Caspi A, Sugden K, Moffitt TE, et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science. 2003;18:386-389.
    • (2003) Science. , vol.18 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3
  • 98
    • 67649206975 scopus 로고    scopus 로고
    • Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: A meta-analysis
    • Risch N, Herrell R, Lehner T, et al. Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA. 2009;301:2462-2471.
    • (2009) JAMA. , vol.301 , pp. 2462-2471
    • Risch, N.1    Herrell, R.2    Lehner, T.3
  • 99
  • 100
    • 23044514669 scopus 로고    scopus 로고
    • Epigenetic differences arise during the lifetime of monozygotic twins
    • Fraga MF, Ballestar E, Paz MF, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA. 2005;102:10604-10609.
    • (2005) Proc Natl Acad Sci USA. , vol.102 , pp. 10604-10609
    • Fraga, M.F.1    Ballestar, E.2    Paz, M.F.3
  • 101
    • 33947653784 scopus 로고    scopus 로고
    • Mood is indirectly related to serotonin, norepinephrine, and dopamine levels in humans: A meta-analysis of monoamine depletion studies
    • Ruhe HG, Mason NS, Schene AH. Mood is indirectly related to serotonin, norepinephrine, and dopamine levels in humans: a meta-analysis of monoamine depletion studies. Mol Psychiatry. 2007;12:331-359.
    • (2007) Mol Psychiatry. , vol.12 , pp. 331-359
    • Ruhe, H.G.1    Mason, N.S.2    Schene, A.H.3
  • 102
    • 0026781307 scopus 로고
    • Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons
    • Watanabe Y, Gould E, McEwen BS. Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. Brain Res. 1992;588:341-345.
    • (1992) Brain Res. , vol.588 , pp. 341-345
    • Watanabe, Y.1    Gould, E.2    McEwen, B.S.3
  • 103
    • 0242332183 scopus 로고    scopus 로고
    • Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
    • Chen WG, Chang Q, Lin Y, et al. Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science. 2003;302:885-889.
    • (2003) Science. , vol.302 , pp. 885-889
    • Chen, W.G.1    Chang, Q.2    Lin, Y.3
  • 104
    • 0034742675 scopus 로고    scopus 로고
    • Nuclear factor kappaB is a critical determinant in N-methyl-D-aspartate receptor-mediated neuroprotection
    • Lipsky RH, Xu K, Zhu D, et al. Nuclear factor kappaB is a critical determinant in N-methyl-D-aspartate receptor-mediated neuroprotection. J Neurochem. 2001;78: 254-264.
    • (2001) J Neurochem. , vol.78 , pp. 254-264
    • Lipsky, R.H.1    Xu, K.2    Zhu, D.3
  • 105
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
    • Martinowich K, Hattor I, Wu H, et al. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science. 2003;302:890-893.
    • (2003) Science. , vol.302 , pp. 890-893
    • Martinowich, K.1    Hattor, I.2    Wu, H.3
  • 106
    • 0028228152 scopus 로고
    • Developmental regulation of brainderived neurotrophic factor messenger RNAs transcribed from different promoters in the rat brain
    • Timmusk T, Belluardo N, Persson H, Metsis M. Developmental regulation of brainderived neurotrophic factor messenger RNAs transcribed from different promoters in the rat brain. Neuroscience. 1994;60:287-291.
    • (1994) Neuroscience. , vol.60 , pp. 287-291
    • Timmusk, T.1    Belluardo, N.2    Persson, H.3    Metsis, M.4
  • 107
    • 65249155356 scopus 로고    scopus 로고
    • Human BDNF isoforms are differentially expressed in cocaine addicts and are sorted to the regulated secretory pathway independent of the Met66 substitution
    • Jiang X, Zhou J, Mash DC, Marini AM, Lipsky RH. Human BDNF isoforms are differentially expressed in cocaine addicts and are sorted to the regulated secretory pathway independent of the Met66 substitution. Neuromol Med. 2009;11:1-12.
    • (2009) Neuromol Med. , vol.11 , pp. 1-12
    • Jiang, X.1    Zhou, J.2    Mash, D.C.3    Marini, A.M.4    Lipsky, R.H.5
  • 108
    • 31144467231 scopus 로고    scopus 로고
    • Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine
    • Liu QR, Lu L, Zhu XG, Gong JP, Shaham Y, Uhl GR. Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine. Brain Res. 2006;1067:1-12.
    • (2006) Brain Res. , vol.1067 , pp. 1-12
    • Liu, Q.R.1    Lu, L.2    Zhu, X.G.3    Gong, J.P.4    Shaham, Y.5    Uhl, G.R.6
  • 109
    • 3042700000 scopus 로고    scopus 로고
    • Role of brain-derived neurotrophic factor and NF-kappaB in neuronal plasticity and survival: From genes to phenotype
    • Marini AM, Jiang X, Wu X, et al. Role of brain-derived neurotrophic factor and NF-kappaB in neuronal plasticity and survival: from genes to phenotype. Restor Neurol Neurosci. 2004;22:121-130.
    • (2004) Restor Neurol Neurosci. , vol.22 , pp. 121-130
    • Marini, A.M.1    Jiang, X.2    Wu, X.3
  • 110
    • 84894303609 scopus 로고    scopus 로고
    • Epigenetic mechanisms regulating learning and long-term memory
    • Lipsky RH. Epigenetic mechanisms regulating learning and long-term memory. Int J Dev Neurosci. 2013;31:353-358.
    • (2013) Int J Dev Neurosci. , vol.31 , pp. 353-358
    • Lipsky, R.H.1
  • 111
    • 63449085750 scopus 로고    scopus 로고
    • Lasting epigenetic influence of early-life adversity on the BDNF gene
    • Roth TL, Lubin FD, Funk AJ, Sweatt JD. Lasting epigenetic influence of early-life adversity on the BDNF gene. Biol Psychiatry. 2009;65:760-769.
    • (2009) Biol Psychiatry. , vol.65 , pp. 760-769
    • Roth, T.L.1    Lubin, F.D.2    Funk, A.J.3    Sweatt, J.D.4
  • 112
    • 41549107883 scopus 로고    scopus 로고
    • Genderrelated urocortin 1 and brain-derived neurotrophic factor expression in the adult human midbrain of suicide victims with depression
    • Kozicz T, Tilburg-Ouwens D, Faludi G, Palkovits M, Roubos E. Genderrelated urocortin 1 and brain-derived neurotrophic factor expression in the adult human midbrain of suicide victims with depression. Neuroscience. 2008;152: 1015-1023.
    • (2008) Neuroscience. , vol.152 , pp. 1015-1023
    • Kozicz, T.1    Tilburg-Ouwens, D.2    Faludi, G.3    Palkovits, M.4    Roubos, E.5
  • 113
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • Chen B, Dowlatshahi D, MacQueen GM, Wang JF, Young LT. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry. 2001;50:260-265.
    • (2001) Biol Psychiatry. , vol.50 , pp. 260-265
    • Chen, B.1    Dowlatshahi, D.2    Macqueen, G.M.3    Wang, J.F.4    Young, L.T.5
  • 114
    • 84868540518 scopus 로고    scopus 로고
    • Synaptic mechanisms underlying rapid antidepressant action of ketamine
    • Kavalali ET, Monteggia LM. Synaptic mechanisms underlying rapid antidepressant action of ketamine. Am J Psychiatry. 2012;169:1150-1156.
    • (2012) Am J Psychiatry. , vol.169 , pp. 1150-1156
    • Kavalali, E.T.1    Monteggia, L.M.2
  • 115
    • 84873743622 scopus 로고    scopus 로고
    • Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: Modulation by antidepressant treatment
    • Guiddotti G, Calabrese F, Anacker C, Racagni G, Pariante CM, Riva MA. Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: modulation by antidepressant treatment. Neuropsychopharmacology. 2013;38:616-627.
    • (2013) Neuropsychopharmacology. , vol.38 , pp. 616-627
    • Guiddotti, G.1    Calabrese, F.2    Anacker, C.3    Racagni, G.4    Pariante, C.M.5    Riva, M.A.6
  • 116
    • 3042589127 scopus 로고    scopus 로고
    • Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures
    • Tsankova NM, Kumar A, Nestler EJ. Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J Neurosci. 2004;24:5603-5610.
    • (2004) J Neurosci. , vol.24 , pp. 5603-5610
    • Tsankova, N.M.1    Kumar, A.2    Nestler, E.J.3
  • 117
    • 33645357786 scopus 로고    scopus 로고
    • Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action
    • Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci. 2006;9:519-525.
    • (2006) Nat Neurosci. , vol.9 , pp. 519-525
    • Tsankova, N.M.1    Berton, O.2    Renthal, W.3    Kumar, A.4    Neve, R.L.5    Nestler, E.J.6
  • 118
    • 57749181777 scopus 로고    scopus 로고
    • Long-lasting behavioural and molecular alterations induced by early postnatal fluoxetine exposure are restored by chronic fluoxetine treatment in adult mice
    • Karpova NN, Lindolm J, Prunnsild P, Timmusk T, Castren E. Long-lasting behavioural and molecular alterations induced by early postnatal fluoxetine exposure are restored by chronic fluoxetine treatment in adult mice. Eur Neuropsychopharmacol. 2009;19:97-108.
    • (2009) Eur Neuropsychopharmacol. , vol.19 , pp. 97-108
    • Karpova, N.N.1    Lindolm, J.2    Prunnsild, P.3    Timmusk, T.4    Castren, E.5
  • 119
    • 62449271516 scopus 로고    scopus 로고
    • The role of L-methylfolate in depressive disorders
    • Farah A. The role of L-methylfolate in depressive disorders. CNS Spectr. 2009;14:2-7.
    • (2009) CNS Spectr. , vol.14 , pp. 2-7
    • Farah, A.1
  • 120
    • 84876278080 scopus 로고    scopus 로고
    • Methylation-dependent and -independent genomic targeting principles of the MBD protein family
    • Baubec T, Ivánek R, Lienert F, Schübeler D. Methylation-dependent and -independent genomic targeting principles of the MBD protein family. Cell. 2013;153:480-492.
    • (2013) Cell. , vol.153 , pp. 480-492
    • Baubec, T.1    Ivánek, R.2    Lienert, F.3    Schübeler, D.4
  • 121
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • Chahrour M, Jung SY, Shaw C, et al. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science. 2008;320:1224-1229.
    • (2008) Science. , vol.320 , pp. 1224-1229
    • Chahrour, M.1    Jung, S.Y.2    Shaw, C.3
  • 122
    • 31444434393 scopus 로고    scopus 로고
    • The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression
    • Chang Q, Khare G, Dani V, Nelson S, Jaenisch R. The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression. Neuron. 2006;49:341-348.
    • (2006) Neuron. , vol.49 , pp. 341-348
    • Chang, Q.1    Khare, G.2    Dani, V.3    Nelson, S.4    Jaenisch, R.5
  • 123
    • 79960310830 scopus 로고    scopus 로고
    • Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample
    • Uddin M, Koenen KC, Aiello AE, Wildman DE, de los Santos R, Galea S. Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample. Psychol Med. 2011;41:997-1007.
    • (2011) Psychol Med. , vol.41 , pp. 997-1007
    • Uddin, M.1    Koenen, K.C.2    Aiello, A.E.3    Wildman, D.E.4    De Los Santos, R.5    Galea, S.6
  • 124
    • 64649095655 scopus 로고    scopus 로고
    • Depression and immunity: Inflammation and depressive symptoms in multiple sclerosis
    • Gold SM, Irwin MR. Depression and immunity: inflammation and depressive symptoms in multiple sclerosis. Immunol Allergy Clin North Am. 2009;29:309-320.
    • (2009) Immunol Allergy Clin North Am. , vol.29 , pp. 309-320
    • Gold, S.M.1    Irwin, M.R.2
  • 125
    • 63449122724 scopus 로고    scopus 로고
    • Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression
    • Miller AH, Maletic V, Raison CL. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol Psychiatry. 2009;65:732-741.
    • (2009) Biol Psychiatry. , vol.65 , pp. 732-741
    • Miller, A.H.1    Maletic, V.2    Raison, C.L.3
  • 126
    • 84871768667 scopus 로고    scopus 로고
    • Genome-wide DNA methylation scan in major depressive disorder
    • Sabunciyan S, Aryee MJ, Irizarry RA, et al. Genome-wide DNA methylation scan in major depressive disorder. PLoS One. 2012;7:e34451.
    • (2012) PLoS One. , vol.7 , pp. e34451
    • Sabunciyan, S.1    Aryee, M.J.2    Irizarry, R.A.3
  • 127
    • 84903278704 scopus 로고    scopus 로고
    • Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness
    • Kohen R, Dobra A, Tracy JH, Haugen E. Transcriptome profiling of human hippocampus dentate gyrus granule cells in mental illness. Transl Psychiatry. 2014;4:e366.
    • (2014) Transl Psychiatry. , vol.4 , pp. e366
    • Kohen, R.1    Dobra, A.2    Tracy, J.H.3    Haugen, E.4
  • 128
    • 65249157050 scopus 로고    scopus 로고
    • Epigenetics, DNA methylation, and chromatin modifying drugs
    • Szyf M. Epigenetics, DNA methylation, and chromatin modifying drugs. Annu Rev Pharmacol Toxicol. 2009;49:243-263.
    • (2009) Annu Rev Pharmacol Toxicol. , vol.49 , pp. 243-263
    • Szyf, M.1
  • 129
    • 84875700729 scopus 로고    scopus 로고
    • A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression
    • Guintivano J, Aryee MJ, Kaminsky ZA. A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression. Epigenetics. 2013;8:290-302.
    • (2013) Epigenetics. , vol.8 , pp. 290-302
    • Guintivano, J.1    Aryee, M.J.2    Kaminsky, Z.A.3
  • 130
    • 36749052947 scopus 로고    scopus 로고
    • DNA methylation signatures within the human brain
    • Ladd-Acosta C, Pevsner J, Sabunciyan S, et al. DNA methylation signatures within the human brain. Am J Hum Genet. 2007;81:1304-1315.
    • (2007) Am J Hum Genet. , vol.81 , pp. 1304-1315
    • Ladd-Acosta, C.1    Pevsner, J.2    Sabunciyan, S.3
  • 133
    • 84863380672 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants
    • Yu H, Wang DD, Wang Y, Liu T, Lee FS, Chen ZY. Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants. J Neurosci. 2012;32:4092-4101.
    • (2012) J Neurosci. , vol.32 , pp. 4092-4101
    • Yu, H.1    Wang, D.D.2    Wang, Y.3    Liu, T.4    Lee, F.S.5    Chen, Z.Y.6
  • 134
    • 84858667364 scopus 로고    scopus 로고
    • Altered maternal micronutrients (folic acid, vitamin B(12)) and omega 3 fatty acids through oxidative stress may reduce neurotrophic factors in preterm pregnancy
    • Dhobale M, Joshi S. Altered maternal micronutrients (folic acid, vitamin B(12)) and omega 3 fatty acids through oxidative stress may reduce neurotrophic factors in preterm pregnancy. J Matern Fetal Neonatal Med. 2012;25:317-323.
    • (2012) J Matern Fetal Neonatal Med. , vol.25 , pp. 317-323
    • Dhobale, M.1    Joshi, S.2
  • 135
    • 84895963153 scopus 로고    scopus 로고
    • Maternal exposure to fluoxetine during gestation and lactation affects the DNA methylation programming of rat's offspring: Modulation by folic acid supplementation
    • Toffoli LV, Rodrigues Jr GM, Oliveira JF, et al. Maternal exposure to fluoxetine during gestation and lactation affects the DNA methylation programming of rat's offspring: modulation by folic acid supplementation. Behav Brain Res. 2014;265: 142-147.
    • (2014) Behav Brain Res. , vol.265 , pp. 142-147
    • Toffoli, L.V.1    Rodrigues, G.M.2    Oliveira, J.F.3
  • 136
    • 72749125429 scopus 로고    scopus 로고
    • Folate in depression: Efficacy, safety, differences in formulations, and clinical issues
    • Fava M, Mischoulon D. Folate in depression: efficacy, safety, differences in formulations, and clinical issues. J Clin Psychiatry. 2009;70:12-17.
    • (2009) J Clin Psychiatry. , vol.70 , pp. 12-17
    • Fava, M.1    Mischoulon, D.2
  • 138
    • 84903377818 scopus 로고    scopus 로고
    • Effect of adjunctive L-methylfolate 15 mg among inadequate responders to SSRIs in depressed patients who were stratified by biomarker levels and genotype: Results from a randomized clinical trial
    • Papakostas GI, Shelton RC, Zajecka JM, et al. Effect of adjunctive L-methylfolate 15 mg among inadequate responders to SSRIs in depressed patients who were stratified by biomarker levels and genotype: results from a randomized clinical trial. J Clin Psychiatry. 2014;75:855-863.
    • (2014) J Clin Psychiatry. , vol.75 , pp. 855-863
    • Papakostas, G.I.1    Shelton, R.C.2    Zajecka, J.M.3
  • 139
    • 84878662972 scopus 로고    scopus 로고
    • S-Adenosyl-L-methionine augmentation in patients with stage II treatment-resistant major depressive disorder: An open label, fixed dose, single-blind study
    • De Berardis D, Marini S, Serroni N, et al. S-Adenosyl-L-methionine augmentation in patients with stage II treatment-resistant major depressive disorder: an open label, fixed dose, single-blind study. ScientificWorldJournal. 2013;2013:204649.
    • (2013) ScientificWorldJournal. , vol.2013 , pp. 204649
    • De Berardis, D.1    Marini, S.2    Serroni, N.3
  • 140
    • 77955360283 scopus 로고    scopus 로고
    • S-Adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: A double-blind, randomized clinical trial
    • Papakostas GI, Mischoulon D, Shyu I, Alpert JE, Fava M. S-Adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial. Am J Psychiatry. 2010;167:942-948.
    • (2010) Am J Psychiatry. , vol.167 , pp. 942-948
    • Papakostas, G.I.1    Mischoulon, D.2    Shyu, I.3    Alpert, J.E.4    Fava, M.5
  • 141
    • 84899797176 scopus 로고    scopus 로고
    • S-Adenosyl methionine (SAMe) versus escitalopram and placebo in major depression RCT: Efficacy and effects of histamine and carnitine as moderators of response
    • Sarris J, Papakostas GI, Vitolo O, Fava M, Mischoulon D. S-Adenosyl methionine (SAMe) versus escitalopram and placebo in major depression RCT: efficacy and effects of histamine and carnitine as moderators of response. J Affect Disord. 2014;164:76-81.
    • (2014) J Affect Disord. , vol.164 , pp. 76-81
    • Sarris, J.1    Papakostas, G.I.2    Vitolo, O.3    Fava, M.4    Mischoulon, D.5
  • 142
    • 72749083114 scopus 로고    scopus 로고
    • Evidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder
    • Papakostas GI. Evidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder. J Clin Psychiatry. 2009;70(Suppl. 5):18-22.
    • (2009) J Clin Psychiatry. , vol.70 , pp. 18-22
    • Papakostas, G.I.1
  • 143
    • 84871842069 scopus 로고    scopus 로고
    • Folates and S-adenosylmethionine for major depressive disorder
    • Papakostas GI, Cassiello CF, Iovieno N. Folates and S-adenosylmethionine for major depressive disorder. Can J Psychiatry. 2012;57:406-413.
    • (2012) Can J Psychiatry. , vol.57 , pp. 406-413
    • Papakostas, G.I.1    Cassiello, C.F.2    Iovieno, N.3
  • 144
    • 84867713876 scopus 로고    scopus 로고
    • Mü ller DJ. Genetics and personalized medicine in antidepressant treatment
    • Gvozdic K, Brandl EJ, Taylor DL, Mü ller DJ. Genetics and personalized medicine in antidepressant treatment. Curr Pharm Des. 2012;18:5853-5878.
    • (2012) Curr Pharm Des. , vol.18 , pp. 5853-5878
    • Gvozdic, K.1    Brandl, E.J.2    Taylor, D.L.3


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